Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour

Neuropharmacology

Volumn 115, Issue , 2017, Pages 128-138

  Wood, Christian M ^a   Nicolas, Celine S ^a   Choi, Sun Lim ^a   Roman, Erika ^b   Nylander, Ingrid ^b   Fernandez Teruel, Alberto ^c   Kiianmaa, Kalervo ^d   Bienkowski, Przemyslaw ^e   de Jong, Trynke R ^f   Colombo, Giancarlo ^g   Chastagnier, Denis ^h   Wafford, Keith A ⁱ   Collingridge, Graham L ^a   Wildt, Sheryl J ^j   Conway Campbell, Becky L ^k   Robinson, Emma S J ^a   Lodge, David ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UPPSALA UNIVERSITY   (Sweden)

^c INSTITUT DE NEUROCIÈNCIES   (Spain)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^f UNIVERSITY OF REGENSBURG   (Germany)

^g CNR   (Italy)

^h Janvier Labs   (France)

ⁱ ELI LILLY AND COMPANY   (United States)

^j Department of Bioanalytical Services   (United States)

^k UNIVERSITY OF BRISTOL   (United Kingdom)

more..

Author keywords

Alcohol preference; Anxiety; Emotionality; Grm2 mutation; Han Wistar rats; Metabotropic glutamate receptor; mGlu2; Selectively bred rats; Wistar rats

Indexed keywords

CYSTEINE; METABOTROPIC RECEPTOR 2; CYSTINE; METABOTROPIC RECEPTOR;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONTROLLED STUDY; EMOTION; EMOTIONALITY; EXON; GENE MUTATION; GENOTYPE; GRM2 GENE; HIGH RISK BEHAVIOR; IMPULSIVENESS; NONHUMAN; POINT MUTATION; PREVALENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVIEW; STOP CODON; ANIMAL; DEFICIENCY; DRINKING BEHAVIOR; GENETICS; HIPPOCAMPUS; KNOCKOUT MOUSE; MUTATION; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; PSYCHOLOGY; SPECIES DIFFERENCE; WISTAR RAT;

ALCOHOL DRINKING; ANIMALS; CYSTINE; EMOTIONS; HIPPOCAMPUS; MICE, KNOCKOUT; MUTATION; ORGAN CULTURE TECHNIQUES; PREVALENCE; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RISK-TAKING; SPECIES SPECIFICITY;

EID: 84962768292     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2016.03.020     Document Type: Review

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