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Volumn 17, Issue 5, 2016, Pages 671-681

ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function

Author keywords

ATM; ATR; DNA damage response; PALB2 phosphorylation; RAD51

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BRCA2 PROTEIN; HISTONE H2AX; HYDROXYUREA; PALB2 PROTEIN; PROTEIN; RAD51 PROTEIN; SERINE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; ACTIN; ATR PROTEIN, HUMAN; NUCLEAR PROTEIN; PALB2 PROTEIN, HUMAN; PROTEIN BINDING; TUMOR SUPPRESSOR PROTEIN;

EID: 84962754623     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201541455     Document Type: Article
Times cited : (52)

References (43)
  • 1
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP, Bartek J, (2009) The DNA-damage response in human biology and disease. Nature 461: 1071-1078
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 2
    • 84865620494 scopus 로고    scopus 로고
    • Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
    • Thompson LH, (2012) Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography. Mutat Res 751: 158-246
    • (2012) Mutat Res , vol.751 , pp. 158-246
    • Thompson, L.H.1
  • 4
    • 84875423827 scopus 로고    scopus 로고
    • The ATM protein kinase: Regulating the cellular response to genotoxic stress, and more
    • Shiloh Y, Ziv Y, (2013) The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nat Rev Mol Cell Biol 14: 197-210
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 197-210
    • Shiloh, Y.1    Ziv, Y.2
  • 5
    • 84930379261 scopus 로고    scopus 로고
    • Exploiting replicative stress to treat cancer
    • Dobbelstein M, Sorensen CS, (2015) Exploiting replicative stress to treat cancer. Nat Rev Drug Discov 14: 405-423
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 405-423
    • Dobbelstein, M.1    Sorensen, C.S.2
  • 6
    • 84938512025 scopus 로고    scopus 로고
    • DNA damage in cancer therapeutics: A boon or a curse?
    • Khanna A, (2015) DNA damage in cancer therapeutics: a boon or a curse? Cancer Res 75: 2133-2138
    • (2015) Cancer Res , vol.75 , pp. 2133-2138
    • Khanna, A.1
  • 9
    • 84896995635 scopus 로고    scopus 로고
    • Two decades after BRCA: Setting paradigms in personalized cancer care and prevention
    • Couch FJ, Nathanson KL, Offit K, (2014) Two decades after BRCA: setting paradigms in personalized cancer care and prevention. Science 343: 1466-1470
    • (2014) Science , vol.343 , pp. 1466-1470
    • Couch, F.J.1    Nathanson, K.L.2    Offit, K.3
  • 10
    • 84930950753 scopus 로고    scopus 로고
    • Genetics of breast cancer: A topic in evolution
    • Shiovitz S, Korde LA, (2015) Genetics of breast cancer: a topic in evolution. Ann Oncol 26: 1291-1299
    • (2015) Ann Oncol , vol.26 , pp. 1291-1299
    • Shiovitz, S.1    Korde, L.A.2
  • 12
    • 66349096607 scopus 로고    scopus 로고
    • PALB2 is an integral component of the BRCA complex required for homologous recombination repair
    • Sy SM, Huen MS, Chen J, (2009) PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci USA 106: 7155-7160
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7155-7160
    • Sy, S.M.1    Huen, M.S.2    Chen, J.3
  • 13
    • 67651166786 scopus 로고    scopus 로고
    • PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2
    • Zhang F, Fan Q, Ren K, Andreassen PR, (2009) PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. Mol Cancer Res 7: 1110-1118
    • (2009) Mol Cancer Res , vol.7 , pp. 1110-1118
    • Zhang, F.1    Fan, Q.2    Ren, K.3    Andreassen, P.R.4
  • 14
    • 62549115236 scopus 로고    scopus 로고
    • PALB2 links BRCA1 and BRCA2 in the DNA-damage response
    • Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B, Yu X, (2009) PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 19: 524-529
    • (2009) Curr Biol , vol.19 , pp. 524-529
    • Zhang, F.1    Ma, J.2    Wu, J.3    Ye, L.4    Cai, H.5    Xia, B.6    Yu, X.7
  • 15
    • 79958694525 scopus 로고    scopus 로고
    • A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling
    • Cotta-Ramusino C, McDonald ER III, Hurov K, Sowa ME, Harper JW, Elledge SJ, (2011) A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Science 332: 1313-1317
    • (2011) Science , vol.332 , pp. 1313-1317
    • Cotta-Ramusino, C.1    McDonald, E.R.2    Hurov, K.3    Sowa, M.E.4    Harper, J.W.5    Elledge, S.J.6
  • 17
    • 35548978945 scopus 로고    scopus 로고
    • The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
    • Lobrich M, Jeggo PA, (2007) The impact of a negligent G2/M checkpoint on genomic instability and cancer induction. Nat Rev Cancer 7: 861-869
    • (2007) Nat Rev Cancer , vol.7 , pp. 861-869
    • Lobrich, M.1    Jeggo, P.A.2
  • 18
    • 84861526824 scopus 로고    scopus 로고
    • Checkpoint control and cancer
    • Medema RH, Macurek L, (2012) Checkpoint control and cancer. Oncogene 31: 2601-2613
    • (2012) Oncogene , vol.31 , pp. 2601-2613
    • Medema, R.H.1    Macurek, L.2
  • 19
    • 77649131406 scopus 로고    scopus 로고
    • Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
    • Moynahan ME, Jasin M, (2010) Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol 11: 196-207
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 196-207
    • Moynahan, M.E.1    Jasin, M.2
  • 20
    • 80755187806 scopus 로고    scopus 로고
    • Double-strand break end resection and repair pathway choice
    • Symington LS, Gautier J, (2011) Double-strand break end resection and repair pathway choice. Annu Rev Genet 45: 247-271
    • (2011) Annu Rev Genet , vol.45 , pp. 247-271
    • Symington, L.S.1    Gautier, J.2
  • 22
    • 35648986560 scopus 로고    scopus 로고
    • Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination
    • Takeda S, Nakamura K, Taniguchi Y, Paull TT, (2007) Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination. Mol Cell 28: 351-352
    • (2007) Mol Cell , vol.28 , pp. 351-352
    • Takeda, S.1    Nakamura, K.2    Taniguchi, Y.3    Paull, T.T.4
  • 24
    • 84905493192 scopus 로고    scopus 로고
    • End resection at double-strand breaks: Mechanism and regulation
    • a016436
    • Symington LS, (2014) End resection at double-strand breaks: mechanism and regulation. Cold Spring Harb Perspect Biol 6: a016436
    • (2014) Cold Spring Harb Perspect Biol , vol.6
    • Symington, L.S.1
  • 27
    • 77957975815 scopus 로고    scopus 로고
    • Purified human BRCA2 stimulates RAD51-mediated recombination
    • Jensen RB, Carreira A, Kowalczykowski SC, (2010) Purified human BRCA2 stimulates RAD51-mediated recombination. Nature 467: 678-683
    • (2010) Nature , vol.467 , pp. 678-683
    • Jensen, R.B.1    Carreira, A.2    Kowalczykowski, S.C.3
  • 28
    • 77957804215 scopus 로고    scopus 로고
    • Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
    • Liu J, Doty T, Gibson B, Heyer WD, (2010) Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nat Struct Mol Biol 17: 1260-1262
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 1260-1262
    • Liu, J.1    Doty, T.2    Gibson, B.3    Heyer, W.D.4
  • 33
    • 84946919323 scopus 로고    scopus 로고
    • ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response
    • Guo Y, Feng W, Sy SM, Huen MS, (2015) ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response. J Biol Chem 290: 27545-27556
    • (2015) J Biol Chem , vol.290 , pp. 27545-27556
    • Guo, Y.1    Feng, W.2    Sy, S.M.3    Huen, M.S.4
  • 35
    • 0014214159 scopus 로고
    • Studies on the acid-soluble nucleotide pool in Escherichia coli. IV. Effects of hydroxyurea
    • Neuhard J, (1967) Studies on the acid-soluble nucleotide pool in Escherichia coli. IV. Effects of hydroxyurea. Biochim Biophys Acta 145: 1-6
    • (1967) Biochim Biophys Acta , vol.145 , pp. 1-6
    • Neuhard, J.1
  • 36
    • 0014321572 scopus 로고
    • Inhibition of ribonucleoside diphosphate reductase by hydroxyurea
    • Krakoff IH, Brown NC, Reichard P, (1968) Inhibition of ribonucleoside diphosphate reductase by hydroxyurea. Cancer Res 28: 1559-1565
    • (1968) Cancer Res , vol.28 , pp. 1559-1565
    • Krakoff, I.H.1    Brown, N.C.2    Reichard, P.3
  • 37
    • 84926432359 scopus 로고    scopus 로고
    • Homologous recombination and human health: The roles of BRCA1, BRCA2, and associated proteins
    • Prakash R, Zhang Y, Feng W, Jasin M, (2015) Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins. Cold Spring Harb Perspect Biol 7: a016600
    • (2015) Cold Spring Harb Perspect Biol , vol.7 , pp. a016600
    • Prakash, R.1    Zhang, Y.2    Feng, W.3    Jasin, M.4
  • 38
    • 84867197361 scopus 로고    scopus 로고
    • From yeast to mammals: Recent advances in genetic control of homologous recombination
    • Karpenshif Y, Bernstein KA, (2012) From yeast to mammals: recent advances in genetic control of homologous recombination. DNA Repair (Amst) 11: 781-788
    • (2012) DNA Repair (Amst) , vol.11 , pp. 781-788
    • Karpenshif, Y.1    Bernstein, K.A.2
  • 39
    • 77954021548 scopus 로고    scopus 로고
    • Promotion and regulation of homologous recombination by DNA helicases
    • Colavito S, Prakash R, Sung P, (2010) Promotion and regulation of homologous recombination by DNA helicases. Methods 51: 329-335
    • (2010) Methods , vol.51 , pp. 329-335
    • Colavito, S.1    Prakash, R.2    Sung, P.3
  • 40
    • 84891014338 scopus 로고    scopus 로고
    • Double-strand break repair: 53BP1 comes into focus
    • Panier S, Boulton SJ, (2014) Double-strand break repair: 53BP1 comes into focus. Nat Rev Mol Cell Biol 15: 7-18
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 7-18
    • Panier, S.1    Boulton, S.J.2
  • 43
    • 0035893363 scopus 로고    scopus 로고
    • Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
    • Pierce AJ, Hu P, Han M, Ellis N, Jasin M, (2001) Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev 15: 3237-3242
    • (2001) Genes Dev , vol.15 , pp. 3237-3242
    • Pierce, A.J.1    Hu, P.2    Han, M.3    Ellis, N.4    Jasin, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.