-
1
-
-
47049112098
-
Sildenafil augments the beneficial hemodynamic and histopathological effects of amlodipine in nitric oxide-deficient hypertensive rats: role of nitric oxide-cyclic GMP pathway
-
Aboutabl, M. E., Raafat, M., Maklad, Y. A., Kenawy, S. A., and El Din, A. G. (2008). Sildenafil augments the beneficial hemodynamic and histopathological effects of amlodipine in nitric oxide-deficient hypertensive rats: role of nitric oxide-cyclic GMP pathway. Pharmacol. Res. 57, 456-463. doi: 10.1016/j.phrs.2008.05.003.
-
(2008)
Pharmacol. Res
, vol.57
, pp. 456-463
-
-
Aboutabl, M.E.1
Raafat, M.2
Maklad, Y.A.3
Kenawy, S.A.4
El Din, A.G.5
-
2
-
-
84925933942
-
Coconut oil supplementation and physical exercise improves baroreflex sensitivity and oxidative stress in hypertensive rats
-
Alves, N. F. B., Porpino, S. K. P., Monteiro, M. M. O., Gomes, E. R. M., and Braga, V. A. (2015). Coconut oil supplementation and physical exercise improves baroreflex sensitivity and oxidative stress in hypertensive rats. Appl. Physiol. Nutr. Metab. 400, 393-400. doi: 10.1139/apnm-2014-0351.
-
(2015)
Appl. Physiol. Nutr. Metab
, vol.400
, pp. 393-400
-
-
Alves, N.F.B.1
Porpino, S.K.P.2
Monteiro, M.M.O.3
Gomes, E.R.M.4
Braga, V.A.5
-
3
-
-
84871739804
-
Sildenafil restores endothelial function in the apolipoprotein E knockout mouse
-
Balarini, C. M., Leal, M. A., Gomes, I. B. S., Pereira, T. M. C., Gava, A. L., Meyrelles, S. S., et al. (2013). Sildenafil restores endothelial function in the apolipoprotein E knockout mouse. J. Transl. Med. 11:3. doi: 10.1186/1479-5876-11-3.
-
(2013)
J. Transl. Med
, vol.11
, pp. 3
-
-
Balarini, C.M.1
Leal, M.A.2
Gomes, I.B.S.3
Pereira, T.M.C.4
Gava, A.L.5
Meyrelles, S.S.6
-
4
-
-
58149181332
-
Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction
-
Bivalacqua, T. J., Sussan, T. E., Gebska, M. A., Strong, T. D., Berkowitz, D. E., Biswal, S., et al. (2009). Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction. J. Urol. 181, 899-906. doi: 10.1016/j.juro.2008.10.062.
-
(2009)
J. Urol
, vol.181
, pp. 899-906
-
-
Bivalacqua, T.J.1
Sussan, T.E.2
Gebska, M.A.3
Strong, T.D.4
Berkowitz, D.E.5
Biswal, S.6
-
5
-
-
80052736396
-
Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration
-
Bombarda, G., Sabino, J. P. J., Silva, C. A. A., Fazan, R., Salgado, M. C. O., and Salgado, H. C. (2011). Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration. Clinics 66, 1407-1412. doi: 10.1590/S1807-59322011000800017.
-
(2011)
Clinics
, vol.66
, pp. 1407-1412
-
-
Bombarda, G.1
Sabino, J.P.J.2
Silva, C.A.A.3
Fazan, R.4
Salgado, M.C.O.5
Salgado, H.C.6
-
6
-
-
78649907748
-
Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats
-
Botelho-Ono, M. S., Pina, H. V., Sousa, K. H. F., Nunes, F. C., Medeiros, I. A., and Braga, V. A. (2011). Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats. Auton. Neurosci. 159, 38-44. doi: 10.1016/j.autneu.2010.07.025.
-
(2011)
Auton. Neurosci
, vol.159
, pp. 38-44
-
-
Botelho-Ono, M.S.1
Pina, H.V.2
Sousa, K.H.F.3
Nunes, F.C.4
Medeiros, I.A.5
Braga, V.A.6
-
7
-
-
57449084727
-
Cardiovascular responses to peripheral chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry
-
Braga, V. A., Burmeister, M. A., Sharma, R. V., and Davisson, R. L. (2008). Cardiovascular responses to peripheral chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295, R1168-R1174. doi: 10.1152/ajpregu.90375.2008.
-
(2008)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.295
, pp. R1168-R1174
-
-
Braga, V.A.1
Burmeister, M.A.2
Sharma, R.V.3
Davisson, R.L.4
-
8
-
-
80053338242
-
Angiotensin-II-induced reactive oxygen species along the SFO-PVN-RVLM pathway: implications in neurogenic hypertension
-
Braga, V. A., Medeiros, I. A., Ribeiro, T. P., França-Silva, M. S., Botelho-Ono, M. S., and Guimarães, D. D. (2011). Angiotensin-II-induced reactive oxygen species along the SFO-PVN-RVLM pathway: implications in neurogenic hypertension. Braz. J. Med. Biol. Res. 44, 871-876. doi: 10.1590/S0100-879X2011007500088.
-
(2011)
Braz. J. Med. Biol. Res
, vol.44
, pp. 871-876
-
-
Braga, V.A.1
Medeiros, I.A.2
Ribeiro, T.P.3
França-Silva, M.S.4
Botelho-Ono, M.S.5
Guimarães, D.D.6
-
9
-
-
84870186756
-
Cardiac-autonomic imbalance and baroreflex dysfunction in the renovascular angiotensin-dependent hypertensive mouse
-
Campagnaro, B. P., Gava, A. L., Meyrelles, S. S., and Vasquez, E. C. (2012). Cardiac-autonomic imbalance and baroreflex dysfunction in the renovascular angiotensin-dependent hypertensive mouse. Int. J. Hypertens. 2012:968123. doi: 10.1155/2012/968123.
-
(2012)
Int. J. Hypertens
, vol.2012
-
-
Campagnaro, B.P.1
Gava, A.L.2
Meyrelles, S.S.3
Vasquez, E.C.4
-
10
-
-
79251485685
-
The role of oxidative stress in renovascular hypertension
-
Campos, R. R., Oliveira-Sales, E. B., Nishi, E. E., Boim, M. A., Dolnikoff, M. S., and Bergamaschi, C. T. (2011). The role of oxidative stress in renovascular hypertension. Clin. Exp. Pharmacol. Physiol. 38, 144-152. doi: 10.1111/j.1440-1681.2010.05437.x.
-
(2011)
Clin. Exp. Pharmacol. Physiol
, vol.38
, pp. 144-152
-
-
Campos, R.R.1
Oliveira-Sales, E.B.2
Nishi, E.E.3
Boim, M.A.4
Dolnikoff, M.S.5
Bergamaschi, C.T.6
-
11
-
-
84877151078
-
Resistant hypertension
-
Carey, R. M. (2013). Resistant hypertension. Hypertension 61, 746-750. doi: 10.1161/HYPERTENSIONAHA.111.00601.
-
(2013)
Hypertension
, vol.61
, pp. 746-750
-
-
Carey, R.M.1
-
12
-
-
84875258011
-
Blood pressure and diabetes: vicious twins
-
Chokshi, N. P., Grossman, E., and Messerli, F. H. (2013). Blood pressure and diabetes: vicious twins. Heart 99, 577-585. doi: 10.1136/heartjnl-2012-302029.
-
(2013)
Heart
, vol.99
, pp. 577-585
-
-
Chokshi, N.P.1
Grossman, E.2
Messerli, F.H.3
-
13
-
-
84883791484
-
Angiotensin-II-derived reactive oxygen species on baroreflex sensitivity during hypertension: new perspectives
-
de Queiroz, T. M., Monteiro, M. M. O., and Braga, V. A. (2013). Angiotensin-II-derived reactive oxygen species on baroreflex sensitivity during hypertension: new perspectives. Front. Physiol. 4:105. doi: 10.3389/fphys.2013.00105.
-
(2013)
Front. Physiol
, vol.4
, pp. 105
-
-
de Queiroz, T.M.1
Monteiro, M.M.O.2
Braga, V.A.3
-
14
-
-
84908118678
-
Inhibition of phosphodiesterase 5 restores endothelial function in renovascular hypertension
-
Dias, A. T., Cintra, A. S., Frossard, J. C., Palomino, Z., Casarini, D. E., Gomes, I., et al. (2014a). Inhibition of phosphodiesterase 5 restores endothelial function in renovascular hypertension. J. Transl. Med. 12:250. doi: 10.1186/s12967-014-0250-x.
-
(2014)
J. Transl. Med
, vol.12
, pp. 250
-
-
Dias, A.T.1
Cintra, A.S.2
Frossard, J.C.3
Palomino, Z.4
Casarini, D.E.5
Gomes, I.6
-
15
-
-
84896714161
-
Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension
-
Dias, A. T., Rodrigues, B. P., Porto, M. L., Gava, A. L., Balarini, C. M., Freitas, F. P. S., et al. (2014b). Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension. J. Transl. Med. 12:35. doi: 10.1186/1479-5876-12-35.
-
(2014)
J. Transl. Med
, vol.12
, pp. 35
-
-
Dias, A.T.1
Rodrigues, B.P.2
Porto, M.L.3
Gava, A.L.4
Balarini, C.M.5
Freitas, F.P.S.6
-
16
-
-
84877753251
-
Sildenafil increases sympathetically mediated vascular tone in humans
-
Dopp, J. M., Agapitov, A. V., Sinkey, C. A., Haynes, W. G., and Phillips, B. G. (2013). Sildenafil increases sympathetically mediated vascular tone in humans. Am. J. Hypertens. 26, 762-769. doi: 10.1093/ajh/hpt018.
-
(2013)
Am. J. Hypertens
, vol.26
, pp. 762-769
-
-
Dopp, J.M.1
Agapitov, A.V.2
Sinkey, C.A.3
Haynes, W.G.4
Phillips, B.G.5
-
17
-
-
84938566208
-
Sildenafil Improves Vascular Endothelial Structure and Function in Renovascular Hypertension
-
Fahning, B., Dias, A. T., Oliveira, J. P., Gava, A. L., Porto, M. L., Gomes, I. B., et al. (2015). Sildenafil Improves Vascular Endothelial Structure and Function in Renovascular Hypertension. Curr. Pharm. Biotechnol. 16, 823-831. doi: 10.2174/1389201016666150610161330.
-
(2015)
Curr. Pharm. Biotechnol
, vol.16
, pp. 823-831
-
-
Fahning, B.1
Dias, A.T.2
Oliveira, J.P.3
Gava, A.L.4
Porto, M.L.5
Gomes, I.B.6
-
18
-
-
80054761122
-
Common secondary causes of resistant hypertension and rational for treatment
-
Faselis, C., Doumas, M., and Papademetriou, V. (2011). Common secondary causes of resistant hypertension and rational for treatment. Int. J. Hypertens. 2011:236239. doi: 10.4061/2011/236239.
-
(2011)
Int. J. Hypertens
, vol.2011
-
-
Faselis, C.1
Doumas, M.2
Papademetriou, V.3
-
19
-
-
49649127413
-
Sildenafil acts on the central nervous system increasing sympathetic activity
-
Fazan, R., Huber, D. A., Silva, C. A. A., Dias da Silva, V. J., Salgado, M. C. O., and Salgado, H. C. (2008). Sildenafil acts on the central nervous system increasing sympathetic activity. J. Appl. Physiol. 104, 1683-1689. doi: 10.1152/japplphysiol.01142.2007.
-
(2008)
J. Appl. Physiol
, vol.104
, pp. 1683-1689
-
-
Fazan, R.1
Huber, D.A.2
Silva, C.A.A.3
Dias da Silva, V.J.4
Salgado, M.C.O.5
Salgado, H.C.6
-
20
-
-
33746029051
-
Sildenafil reduces cardiovascular remodeling associated with hypertensive cardiomyopathy in NOS inhibitor-treated rats
-
Ferreira-Melo, S. E., Yugar-Toledo, J. C., Coelho, O. R., De Luca, I. M., Tanus-Santos, J. E., Hyslop, S., et al. (2006). Sildenafil reduces cardiovascular remodeling associated with hypertensive cardiomyopathy in NOS inhibitor-treated rats. Eur. J. Pharmacol. 542, 141-147. doi: 10.1016/j.ejphar.2006.04.039.
-
(2006)
Eur. J. Pharmacol
, vol.542
, pp. 141-147
-
-
Ferreira-Melo, S.E.1
Yugar-Toledo, J.C.2
Coelho, O.R.3
De Luca, I.M.4
Tanus-Santos, J.E.5
Hyslop, S.6
-
21
-
-
78651433125
-
Central antioxidant therapy inhibits parasympathetic baroreflex control in conscious rats
-
Giusti, M. F., Sato, M. A., Cardoso, L. M., Braga, V. A., and Colombari, E. (2011). Central antioxidant therapy inhibits parasympathetic baroreflex control in conscious rats. Neurosci. Lett. 489, 115-118. doi: 10.1016/j.neulet.2010.11.077.
-
(2011)
Neurosci. Lett
, vol.489
, pp. 115-118
-
-
Giusti, M.F.1
Sato, M.A.2
Cardoso, L.M.3
Braga, V.A.4
Colombari, E.5
-
22
-
-
85024286205
-
Studies on experimental hypertension. The production of persistent elevation of systolic blood pressure by means of renal ischtemia
-
Goldblatt, B. Y. H., Lynch, J., Ramon, F., Ph, D., and Summerville, W. W. (1934). Studies on experimental hypertension. The production of persistent elevation of systolic blood pressure by means of renal ischtemia. J. Exp. Med. 59, 347-379. doi: 10.1084/jem.59.3.347.
-
(1934)
J. Exp. Med
, vol.59
, pp. 347-379
-
-
Goldblatt, B.Y.H.1
Lynch, J.2
Ramon, F.3
Ph, D.4
Summerville, W.W.5
-
23
-
-
84938336300
-
The sympathetic nervous system alterations in human hypertension
-
Grassi, G., Mark, A., and Esler, M. (2015). The sympathetic nervous system alterations in human hypertension. Circ. Res. 116, 976-991. doi: 10.1161/CIRCRESAHA.116.303604.
-
(2015)
Circ. Res
, vol.116
, pp. 976-991
-
-
Grassi, G.1
Mark, A.2
Esler, M.3
-
24
-
-
84858956376
-
Scavenging of NADPH oxidase-derived superoxide anions improves depressed baroreflex sensitivity in spontaneously hypertensive rats
-
Guimarães, D., Carvalho, C., and Braga, V. A. (2012). Scavenging of NADPH oxidase-derived superoxide anions improves depressed baroreflex sensitivity in spontaneously hypertensive rats. Clin. Exp. Pharmacol. Physiol. 39, 373-378. doi: 10.1111/j.1440-1681.2012.05679.x.
-
(2012)
Clin. Exp. Pharmacol. Physiol
, vol.39
, pp. 373-378
-
-
Guimarães, D.1
Carvalho, C.2
Braga, V.A.3
-
25
-
-
84888413081
-
Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension
-
Guimarães, D. A., Rizzi, E., Ceron, C. S., Pinheiro, L. C., Gerlach, R. F., and Tanus-Santos, J. E. (2013). Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension. Redox Biol. 1, 578-585. doi: 10.1016/j.redox.2013.11.004.
-
(2013)
Redox Biol
, vol.1
, pp. 578-585
-
-
Guimarães, D.A.1
Rizzi, E.2
Ceron, C.S.3
Pinheiro, L.C.4
Gerlach, R.F.5
Tanus-Santos, J.E.6
-
26
-
-
0032151527
-
Baroreflex control of sympathetic activity in experimental hypertension
-
Irigoyen, M. C., and Krieger, E. M. (1998). Baroreflex control of sympathetic activity in experimental hypertension. Braz. J. Med. Biol. Res. 31, 1213-1220. doi: 10.1590/S0100-879X1998000900015.
-
(1998)
Braz. J. Med. Biol. Res
, vol.31
, pp. 1213-1220
-
-
Irigoyen, M.C.1
Krieger, E.M.2
-
27
-
-
84866497986
-
Oxidative stress in the brain causes hypertension via sympathoexcitation
-
Kishi, T., and Hirooka, Y. (2012). Oxidative stress in the brain causes hypertension via sympathoexcitation. Front. Physiol. 3:335. doi: 10.3389/fphys.2012.00335.
-
(2012)
Front. Physiol
, vol.3
, pp. 335
-
-
Kishi, T.1
Hirooka, Y.2
-
28
-
-
0035726144
-
Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release
-
Kishi, T., Hirooka, Y., Sakai, K., Shigematsu, H., Shimokawa, H., and Takeshita, A. (2001). Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release. Hypertension 38, 896-901.
-
(2001)
Hypertension
, vol.38
, pp. 896-901
-
-
Kishi, T.1
Hirooka, Y.2
Sakai, K.3
Shigematsu, H.4
Shimokawa, H.5
Takeshita, A.6
-
29
-
-
23244448247
-
Sildenafil inhibits the formation of superoxide and the expression of gp47phox NAD[P]H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells
-
Koupparis, A. J., Jeremy, J. Y., Muzaffar, S., Persad, R., and Shukla, N. (2005). Sildenafil inhibits the formation of superoxide and the expression of gp47phox NAD[P]H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells. BJU Int. 96, 423-427. doi: 10.1111/j.1464-410X.2005.05643.x.
-
(2005)
BJU Int
, vol.96
, pp. 423-427
-
-
Koupparis, A.J.1
Jeremy, J.Y.2
Muzaffar, S.3
Persad, R.4
Shukla, N.5
-
30
-
-
84928943415
-
Mechanisms of enhanced vasoconstriction in the mouse model of athero-sclerosis: the beneficial effects of sildenafil
-
Leal, M. A., Balarini, C. M., Dias, A. T., Porto, M. L., Gava, A. L., Pereira, T. M. C., et al. (2015). Mechanisms of enhanced vasoconstriction in the mouse model of athero-sclerosis: the beneficial effects of sildenafil. Curr. Pharm. Biotechnol. 16, 517-530. doi: 10.2174/138920101606150407113458.
-
(2015)
Curr. Pharm. Biotechnol
, vol.16
, pp. 517-530
-
-
Leal, M.A.1
Balarini, C.M.2
Dias, A.T.3
Porto, M.L.4
Gava, A.L.5
Pereira, T.M.C.6
-
31
-
-
84870231302
-
Quercetin improves baroreflex sensitivity in spontaneously hypertensive rats
-
Monteiro, M. M. O., França-Silva, M. S., Alves, N. F. B., Porpino, S. K. P., and Braga, V. A. (2012). Quercetin improves baroreflex sensitivity in spontaneously hypertensive rats. Molecules 17, 12997-13008. doi: 10.3390/molecules171112997.
-
(2012)
Molecules
, vol.17
, pp. 12997-13008
-
-
Monteiro, M.M.O.1
França-Silva, M.S.2
Alves, N.F.B.3
Porpino, S.K.P.4
Braga, V.A.5
-
32
-
-
22044435274
-
Unraveling the mystery of goldblatt hypertension
-
Navar, L. G., Zou, L., Von Thun, A., Tarng Wang, C., Imig, J. D., and Mitchell, K. D. (1998). Unraveling the mystery of goldblatt hypertension. News Physiol. Sci. 13, 170-176.
-
(1998)
News Physiol. Sci
, vol.13
, pp. 170-176
-
-
Navar, L.G.1
Zou, L.2
Von Thun, A.3
Tarng Wang, C.4
Imig, J.D.5
Mitchell, K.D.6
-
33
-
-
84878870481
-
Losartan reduces oxidative stress within the rostral ventrolateral medulla of rats with renovascular hypertension
-
Nishi, E. E., Bergamaschi, C. T., Oliveira-Sales, E. B., Simon, K. A., and Campos, R. R. (2013). Losartan reduces oxidative stress within the rostral ventrolateral medulla of rats with renovascular hypertension. Am. J. Hypertens. 26, 858-865. doi: 10.1093/ajh/hpt037.
-
(2013)
Am. J. Hypertens
, vol.26
, pp. 858-865
-
-
Nishi, E.E.1
Bergamaschi, C.T.2
Oliveira-Sales, E.B.3
Simon, K.A.4
Campos, R.R.5
-
34
-
-
77953855167
-
Vitamin C prevents DNA damage induced by renovascular hypertension in multiple organs of Wistar rats
-
Nishi, E. E., Campos, R. R., Bergamaschi, C. T., de Almeida, V. R., and Ribeiro, D. A. (2010a). Vitamin C prevents DNA damage induced by renovascular hypertension in multiple organs of Wistar rats. Hum. Exp. Toxicol. 29, 593-599. doi: 10.1177/0960327109358267.
-
(2010)
Hum. Exp. Toxicol
, vol.29
, pp. 593-599
-
-
Nishi, E.E.1
Campos, R.R.2
Bergamaschi, C.T.3
de Almeida, V.R.4
Ribeiro, D.A.5
-
35
-
-
77951099337
-
Chronic antioxidant treatment improves arterial renovascular hypertension and oxidative stress markers in the kidney in Wistar rats
-
Nishi, E. E., Oliveira-Sales, E. B., Bergamaschi, C. T., Oliveira, T. G. C., Boim, M. A., and Campos, R. R. (2010b). Chronic antioxidant treatment improves arterial renovascular hypertension and oxidative stress markers in the kidney in Wistar rats. Am. J. Hypertens. 23, 473-480. doi: 10.1038/ajh.2010.11.
-
(2010)
Am. J. Hypertens
, vol.23
, pp. 473-480
-
-
Nishi, E.E.1
Oliveira-Sales, E.B.2
Bergamaschi, C.T.3
Oliveira, T.G.C.4
Boim, M.A.5
Campos, R.R.6
-
36
-
-
84865485489
-
Different role of oxidative stress in paraventricular nucleus and rostral ventrolateral medulla in cardiovascular regulation in awake spontaneously hypertensive rats
-
Nishihara, M., Hirooka, Y., Kishi, T., and Sunagawa, K. (2012a). Different role of oxidative stress in paraventricular nucleus and rostral ventrolateral medulla in cardiovascular regulation in awake spontaneously hypertensive rats. J. Hypertens. 30, 1758-1765. doi: 10.1097/HJH.0b013e32835613d7.
-
(2012)
J. Hypertens
, vol.30
, pp. 1758-1765
-
-
Nishihara, M.1
Hirooka, Y.2
Kishi, T.3
Sunagawa, K.4
-
37
-
-
83455164986
-
Oxidative stress in the rostral ventrolateral medulla modulates excitatory and inhibitory inputs in spontaneously hypertensive rats
-
Nishihara, M., Hirooka, Y., Matsukawa, R., Kishi, T., and Sunagawa, K. (2012b). Oxidative stress in the rostral ventrolateral medulla modulates excitatory and inhibitory inputs in spontaneously hypertensive rats. J. Hypertens. 30, 97-106. doi: 10.1097/HJH.0b013e32834e1df4.
-
(2012)
J. Hypertens
, vol.30
, pp. 97-106
-
-
Nishihara, M.1
Hirooka, Y.2
Matsukawa, R.3
Kishi, T.4
Sunagawa, K.5
-
38
-
-
77956181028
-
Superoxide scavenging in the rostral ventrolateral medulla blunts the pressor response to peripheral chemoreflex activation
-
Nunes, F. C., Ribeiro, T. P., França-Silva, M. S., Medeiros, I. A., and Braga, V. A. (2010). Superoxide scavenging in the rostral ventrolateral medulla blunts the pressor response to peripheral chemoreflex activation. Brain Res. 1351, 141-149. doi: 10.1016/j.brainres.2010.07.001.
-
(2010)
Brain Res
, vol.1351
, pp. 141-149
-
-
Nunes, F.C.1
Ribeiro, T.P.2
França-Silva, M.S.3
Medeiros, I.A.4
Braga, V.A.5
-
39
-
-
33750579081
-
Effect of regular phosphodiesterase type 5 inhibition in hypertension
-
Oliver, J. J., Melville, V. P., and Webb, D. J. (2006). Effect of regular phosphodiesterase type 5 inhibition in hypertension. Hypertension 48, 622-627. doi: 10.1161/01.HYP.0000239816.13007.c9.
-
(2006)
Hypertension
, vol.48
, pp. 622-627
-
-
Oliver, J.J.1
Melville, V.P.2
Webb, D.J.3
-
40
-
-
84930171270
-
New approaches in the treatment of hypertension in metabolic diseases
-
Oparil, S., and Schmieder, R. E. (2015). New approaches in the treatment of hypertension in metabolic diseases. Circ. Res. 116, 1074-1095. doi: 10.1161/CIRCRESAHA.116.303603.
-
(2015)
Circ. Res
, vol.116
, pp. 1074-1095
-
-
Oparil, S.1
Schmieder, R.E.2
-
41
-
-
78549285356
-
An update on new oral PDE5 inhibitors for the treatment of erectile dysfunction
-
Palit, V., and Eardley, I. (2010). An update on new oral PDE5 inhibitors for the treatment of erectile dysfunction. Nat. Rev. Urol. 7, 603-609. doi: 10.1038/nrurol.2010.165.
-
(2010)
Nat. Rev. Urol
, vol.7
, pp. 603-609
-
-
Palit, V.1
Eardley, I.2
-
42
-
-
84870203851
-
a-lipoic acid reduces hypertension and increases baroreflex sensitivity in renovascular hypertensive rats
-
Queiroz, T. M., Guimarães, D. D., Mendes-Junior, L. G., and Braga, V. A. (2012). a-lipoic acid reduces hypertension and increases baroreflex sensitivity in renovascular hypertensive rats. Molecules 17, 13357-13367. doi: 10.3390/molecules171113357.
-
(2012)
Molecules
, vol.17
, pp. 13357-13367
-
-
Queiroz, T.M.1
Guimarães, D.D.2
Mendes-Junior, L.G.3
Braga, V.A.4
-
43
-
-
4644287454
-
Sildenafil: emerging cardiovascular indications
-
Raja, S. G., and Nayak, S. H. (2004). Sildenafil: emerging cardiovascular indications. Ann. Thorac. Surg. 78, 1496-1506. doi: 10.1016/j.athoracsur.2004.02.125.
-
(2004)
Ann. Thorac. Surg
, vol.78
, pp. 1496-1506
-
-
Raja, S.G.1
Nayak, S.H.2
-
44
-
-
84883070309
-
Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis
-
Rodrigues, B. P., Campagnaro, B. P., Balarini, C. M., Pereira, T. M. C., Meyrelles, S. S., and Vasquez, E. C. (2013). Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis. Lipids Health Dis. 12:128. doi: 10.1186/1476-511X-12-128.
-
(2013)
Lipids Health Dis
, vol.12
, pp. 128
-
-
Rodrigues, B.P.1
Campagnaro, B.P.2
Balarini, C.M.3
Pereira, T.M.C.4
Meyrelles, S.S.5
Vasquez, E.C.6
-
45
-
-
33847686720
-
Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat
-
Rossoni, G., Manfredi, B., De Gennaro Colonna, V., Berti, M., Guazzi, M., and Berti, F. (2007). Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat. Br. J. Pharmacol. 150, 567-576. doi: 10.1038/sj.bjp.0707131.
-
(2007)
Br. J. Pharmacol
, vol.150
, pp. 567-576
-
-
Rossoni, G.1
Manfredi, B.2
De Gennaro Colonna, V.3
Berti, M.4
Guazzi, M.5
Berti, F.6
-
46
-
-
84872617624
-
Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system
-
Santos, R. A. S., Ferreira, A. J., Verano-Braga, T., and Bader, M. (2013). Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system. J. Endocrinol. 216, R1-R17. doi: 10.1530/joe-12-0341.
-
(2013)
J. Endocrinol
, vol.216
, pp. R1-R17
-
-
Santos, R.A.S.1
Ferreira, A.J.2
Verano-Braga, T.3
Bader, M.4
-
47
-
-
40149096669
-
Improvement of vascular function by acute and chronic treatment with the PDE-5 inhibitor sildenafil in experimental diabetes mellitus
-
Schäfer, A., Fraccarollo, D., Pförtsch, S., Flierl, U., Vogt, C., Pfrang, J., et al. (2008). Improvement of vascular function by acute and chronic treatment with the PDE-5 inhibitor sildenafil in experimental diabetes mellitus. Br. J. Pharmacol. 153, 886-893. doi: 10.1038/sj.bjp.0707459.
-
(2008)
Br. J. Pharmacol
, vol.153
, pp. 886-893
-
-
Schäfer, A.1
Fraccarollo, D.2
Pförtsch, S.3
Flierl, U.4
Vogt, C.5
Pfrang, J.6
-
48
-
-
22144480608
-
Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits
-
Shukla, N., Jones, R., Persad, R., Angelini, G. D., and Jeremy, J. Y. (2005). Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits. Eur. J. Pharmacol. 517, 224-231. doi: 10.1016/j.ejphar.2005.05.012.
-
(2005)
Eur. J. Pharmacol
, vol.517
, pp. 224-231
-
-
Shukla, N.1
Jones, R.2
Persad, R.3
Angelini, G.D.4
Jeremy, J.Y.5
-
49
-
-
33745684325
-
Baroreceptor reflex sensitivity estimated by the sequence technique is reliable in rats
-
Stauss, H. M., Moffitt, J. A., Chapleau, M. W., Abboud, F. M., and Johnson, A. K. (2006). Baroreceptor reflex sensitivity estimated by the sequence technique is reliable in rats. Am. J. Physiol. Heart Circ. Physiol. 291, H482-H483. doi: 10.1152/ajpheart.00228.2006.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.291
, pp. H482-H483
-
-
Stauss, H.M.1
Moffitt, J.A.2
Chapleau, M.W.3
Abboud, F.M.4
Johnson, A.K.5
-
50
-
-
84893820369
-
Phosphodiesterase 5 attenuates the vasodilatory response in renovascular hypertension
-
Stegbauer, J., Friedrich, S., Potthoff, S. A., Broekmans, K., Cortese-Krott, M. M., Quack, I., et al. (2013). Phosphodiesterase 5 attenuates the vasodilatory response in renovascular hypertension. PLoS ONE 8:e80674. doi: 10.1371/journal.pone.0080674.
-
(2013)
PLoS ONE
, vol.8
-
-
Stegbauer, J.1
Friedrich, S.2
Potthoff, S.A.3
Broekmans, K.4
Cortese-Krott, M.M.5
Quack, I.6
-
51
-
-
65549092581
-
Acute effects of sildenafil on flowmediated dilatation and cardiovascular autonomic nerve function in type 2 diabetic patients
-
Stirban, A., Laude, D., Elghozi, J. L., Sander, D., Agelink, M. W., Hilz, M. J., et al. (2009). Acute effects of sildenafil on flowmediated dilatation and cardiovascular autonomic nerve function in type 2 diabetic patients. Diabetes Metab. Res. Rev. 25, 136-143. doi: 10.1002/dmrr.921.
-
(2009)
Diabetes Metab. Res. Rev
, vol.25
, pp. 136-143
-
-
Stirban, A.1
Laude, D.2
Elghozi, J.L.3
Sander, D.4
Agelink, M.W.5
Hilz, M.J.6
-
52
-
-
33750594768
-
Phosphodiesterase 5 inhibition to treat essential hypertension: is this the beginning of the story?
-
Taddei, S., and Ghiadoni, L. (2006). Phosphodiesterase 5 inhibition to treat essential hypertension: is this the beginning of the story? Hypertension 48, 546-548. doi: 10.1161/01.HYP.0000241985.54400.85.
-
(2006)
Hypertension
, vol.48
, pp. 546-548
-
-
Taddei, S.1
Ghiadoni, L.2
-
53
-
-
0030572496
-
Sildenafil (Viagra), a potent and selective inhibitor of type 5 cgmp phosphodiesterase with utility for the treatment of male erectile dysfunction
-
Terrett, N. K., Bell, A. S., Brown, D., and Ellis, P. (1996). Sildenafil (Viagra), a potent and selective inhibitor of type 5 cgmp phosphodiesterase with utility for the treatment of male erectile dysfunction. Bioorg. Med. Chem. Lett. 6, 1819-1824. doi: 10.1016/0960-894X(96)00323-X.
-
(1996)
Bioorg. Med. Chem. Lett
, vol.6
, pp. 1819-1824
-
-
Terrett, N.K.1
Bell, A.S.2
Brown, D.3
Ellis, P.4
-
54
-
-
4444329422
-
Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?
-
Touyz, R. M. (2004). Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? Hypertension 44, 248-252. doi: 10.1161/01.HYP.0000138070.47616.9d.
-
(2004)
Hypertension
, vol.44
, pp. 248-252
-
-
Touyz, R.M.1
-
55
-
-
84901789389
-
Resistant hypertension: a review of diagnosis and management
-
Vongpatanasin, W. (2014). Resistant hypertension: a review of diagnosis and management. JAMA 311, 2216-2224. doi: 10.1001/jama.2014.5180.
-
(2014)
JAMA
, vol.311
, pp. 2216-2224
-
-
Vongpatanasin, W.1
-
56
-
-
0033058382
-
Pharmacokinetics and metabolism of sildenafill in mouse, rat, rabbit, dog and man
-
Walker, D. K., Ackland, M. J., James, G. C., Muirhead, G. J., Rance, D. J., Wastall, P., et al. (1999). Pharmacokinetics and metabolism of sildenafill in mouse, rat, rabbit, dog and man. Xenobiotica 29, 297-310. doi: 10.1080/004982599238687.
-
(1999)
Xenobiotica
, vol.29
, pp. 297-310
-
-
Walker, D.K.1
Ackland, M.J.2
James, G.C.3
Muirhead, G.J.4
Rance, D.J.5
Wastall, P.6
-
57
-
-
84886089553
-
Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension
-
Xia, H., Sriramula, S., Chhabra, K. H., and Lazartigues, E. (2013). Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension. Circ. Res. 113, 1087-1096. doi: 10.1161/CIRCRESAHA.113.301811.
-
(2013)
Circ. Res
, vol.113
, pp. 1087-1096
-
-
Xia, H.1
Sriramula, S.2
Chhabra, K.H.3
Lazartigues, E.4
|