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Volumn 17, Issue 11, 2012, Pages 13357-13367

α-lipoic acid reduces hypertension and increases baroreflex sensitivity in renovascular hypertensive rats

Author keywords

2K1C; Blood pressure; Lipoic acid; Parasympathetic; Reactive oxygen species; Sympathetic

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; THIOCTIC ACID;

EID: 84870203851     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules171113357     Document Type: Article
Times cited : (29)

References (50)
  • 1
    • 2642644904 scopus 로고
    • Multienzyme complexes
    • Reed, L. Multienzyme complexes. Acc. Chem. Res. 1974, 7, 40-46.
    • (1974) Acc. Chem. Res. , vol.7 , pp. 40-46
    • Reed, L.1
  • 2
    • 69949104384 scopus 로고    scopus 로고
    • Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
    • Shay, K.P.; Moreau, R.F.; Smith, E.J.; Smith, A.R.; Hagen, T.M. Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential. Biochim. Biophys. Acta 2009, 1790, 1149-1160.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 1149-1160
    • Shay, K.P.1    Moreau, R.F.2    Smith, E.J.3    Smith, A.R.4    Hagen, T.M.5
  • 3
    • 0035919531 scopus 로고    scopus 로고
    • Effects of α-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats
    • Takaoka, M.; Kobayashi, Y.; Yuba, M.; Ohkita, M.; Matsumura, Y. Effects of α-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats. Eur. J. Pharm. 2001, 424, 121-129.
    • (2001) Eur. J. Pharm. , vol.424 , pp. 121-129
    • Takaoka, M.1    Kobayashi, Y.2    Yuba, M.3    Ohkita, M.4    Matsumura, Y.5
  • 4
    • 0037707713 scopus 로고    scopus 로고
    • Effects of α-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats
    • Maritim, A.C.; Sanders, R.A.; Watkins, J.B. Effects of α-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. J. Nutr. Biochem. 2003, 14, 288-294.
    • (2003) J. Nutr. Biochem. , vol.14 , pp. 288-294
    • Maritim, A.C.1    Sanders, R.A.2    Watkins, J.B.3
  • 5
    • 0030768236 scopus 로고    scopus 로고
    • The pharmacology of the antioxidant lipoic acid
    • Biewenga, G.P.; Haenen, G.R.M.; Bast, A. The pharmacology of the antioxidant lipoic acid. Gen. Pharm. 1997, 29, 315-331.
    • (1997) Gen. Pharm. , vol.29 , pp. 315-331
    • Biewenga, G.P.1    Haenen, G.R.M.2    Bast, A.3
  • 6
    • 75149165328 scopus 로고    scopus 로고
    • Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: A placebo-controlled randomized trial
    • Heinisch, B.B.; Francesconi, M.; Mittermayer, F.; Schaller, G.; Gouya, G.; Wolzt, M.; Pleiner, J. Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: A placebo-controlled randomized trial. Eur. J. Clin. Investig. 2010, 40, 148-154.
    • (2010) Eur. J. Clin. Investig. , vol.40 , pp. 148-154
    • Heinisch, B.B.1    Francesconi, M.2    Mittermayer, F.3    Schaller, G.4    Gouya, G.5    Wolzt, M.6    Pleiner, J.7
  • 7
    • 33745417783 scopus 로고    scopus 로고
    • Autonomic and respiratory responses to microinjection of L-glutamate into the commissural subnucleus of the NTS in the working heart-brainstem preparation of the rat
    • Braga, V.A.; Antunes, V.R.; Machado, B.H. Autonomic and respiratory responses to microinjection of L-glutamate into the commissural subnucleus of the NTS in the working heart-brainstem preparation of the rat. Brain Res. 2006, 1093, 150-160.
    • (2006) Brain Res. , vol.1093 , pp. 150-160
    • Braga, V.A.1    Antunes, V.R.2    Machado, B.H.3
  • 8
    • 31444456824 scopus 로고    scopus 로고
    • Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertension
    • Simic, D.V.; Mimic-Oka, J.; Pljesa-Ercegovac, M.; Savic-Radojevic, A.; Opacic, M.; Matic, D.; Ianovic, B.; Simic, T. Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertension. J. Hum. Hypertens. 2006, 20, 149-155.
    • (2006) J. Hum. Hypertens. , vol.20 , pp. 149-155
    • Simic, D.V.1    Mimic-Oka, J.2    Pljesa-Ercegovac, M.3    Savic-Radojevic, A.4    Opacic, M.5    Matic, D.6    Ianovic, B.7    Simic, T.8
  • 9
    • 78650675859 scopus 로고    scopus 로고
    • Thiol signalling network with an eye to diabetes
    • Matteucci, E.; Giampietro, O. Thiol Signalling Network with an Eye to Diabetes. Molecules 2010, 15, 8890-8903.
    • (2010) Molecules , vol.15 , pp. 8890-8903
    • Matteucci, E.1    Giampietro, O.2
  • 11
    • 23944499810 scopus 로고    scopus 로고
    • Nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension
    • Houston, M.C. Nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension. Prog. Cardiovasc. Dis. 2005, 47, 396-449.
    • (2005) Prog. Cardiovasc. Dis. , vol.47 , pp. 396-449
    • Houston, M.C.1
  • 12
    • 77952543636 scopus 로고    scopus 로고
    • Selective ablation of AT1a receptors in rostral ventrolateral medulla (RVLM) prevents chronic angiotensin-II-dependent hypertension in part by reducing oxidant stress in this region
    • Braga, V.A.; Burmeister, M.A.; Zhou, Y.; Sharma, R.V.; Davisson, R.L. Selective ablation of AT1a receptors in rostral ventrolateral medulla (RVLM) prevents chronic angiotensin-II-dependent hypertension in part by reducing oxidant stress in this region. Hypertension 2008, 52, e36.
    • (2008) Hypertension , vol.52
    • Braga, V.A.1    Burmeister, M.A.2    Zhou, Y.3    Sharma, R.V.4    Davisson, R.L.5
  • 13
    • 78649907748 scopus 로고    scopus 로고
    • Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats
    • Botelho-Ono, M.S.; Pina, H.V.; Sousa, K.H.F.; Nunes, F.C.; Medeiros, I.A.; Braga, V.A. Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats. Auton. Neurosci. 2011, 159, 38-44.
    • (2011) Auton. Neurosci. , vol.159 , pp. 38-44
    • Botelho-Ono, M.S.1    Pina, H.V.2    Sousa, K.H.F.3    Nunes, F.C.4    Medeiros, I.A.5    Braga, V.A.6
  • 14
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling, K.K.; Minieri, C.A.; Ollerenshaw, J.D.; Alexander, R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 1994, 74, 1141-1148.
    • (1994) Circ. Res. , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 15
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NAD(P)H oxidase activation: Contribution to alterations of vasomotor tone
    • Rajagopalan, S.; Kurz, S.; Munzel, T.; Tarpey, M.; Freeman, B.A.; Griendling, K.K.; Harrison, D.G. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NAD(P)H oxidase activation: Contribution to alterations of vasomotor tone. J. Clin. Investig. 1996, 97, 1916-1923.
    • (1996) J. Clin. Investig. , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3    Tarpey, M.4    Freeman, B.A.5    Griendling, K.K.6    Harrison, D.G.7
  • 16
    • 39749191084 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2008 update
    • American Heart Association
    • American Heart Association. Heart disease and stroke statistics - 2008 update. Circulation 2008, 117, 125-146.
    • (2008) Circulation , vol.117 , pp. 125-146
  • 17
    • 0035819458 scopus 로고    scopus 로고
    • Prospects for cardiovascular research
    • Lefkowits, R.J.; Willerson, J. Prospects for cardiovascular research. JAMA 2001, 285, 581-587.
    • (2001) JAMA , vol.285 , pp. 581-587
    • Lefkowits, R.J.1    Willerson, J.2
  • 19
    • 0035460097 scopus 로고    scopus 로고
    • Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR
    • Chen, X.; Touyz, R.M.; Park, J.B.; Schiffrin, E.L. Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR. Hypertension 2001, 38, 606-611.
    • (2001) Hypertension , vol.38 , pp. 606-611
    • Chen, X.1    Touyz, R.M.2    Park, J.B.3    Schiffrin, E.L.4
  • 20
    • 0035726142 scopus 로고    scopus 로고
    • Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats
    • Hong, H.J.; Hsiao, G.; Cheng, T.H.; Yen, M.H. Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats. Hypertension 2001, 38, 1044-1048.
    • (2001) Hypertension , vol.38 , pp. 1044-1048
    • Hong, H.J.1    Hsiao, G.2    Cheng, T.H.3    Yen, M.H.4
  • 23
    • 0031915176 scopus 로고    scopus 로고
    • Baroreflex control of sympathetic nerve activity in essential and secondary hypertension
    • Grassi, G.; Cattaneo, B.M.; Seravalle, G.; Lanfranchi, A.; Mancia, G. Baroreflex control of sympathetic nerve activity in essential and secondary hypertension. Hypertension 1998, 31, 68-72.
    • (1998) Hypertension , vol.31 , pp. 68-72
    • Grassi, G.1    Cattaneo, B.M.2    Seravalle, G.3    Lanfranchi, A.4    Mancia, G.5
  • 25
    • 32644441431 scopus 로고    scopus 로고
    • Effect of chronic N-acetylcysteine treatment on the development of spontaneous hypertension
    • Pechánová, O.; Zichaj, J.; Kojsová, S.; Dobesová, Z.; Jendekovál, L.; Kunes, J. Effect of chronic N-acetylcysteine treatment on the development of spontaneous hypertension. Clin. Sci. 2006, 110, 235-242.
    • (2006) Clin. Sci. , vol.110 , pp. 235-242
    • Pechánová, O.1    Zichaj, J.2    Kojsová, S.3    Dobesová, Z.4    Jendekovál, L.5    Kunes, J.6
  • 27
    • 0024598842 scopus 로고
    • Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells
    • Berk, B.C.; Vekshtein, V.; Gordon, H.M.; Tsuda, T. Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells. Hypertension 1989, 13, 305-314.
    • (1989) Hypertension , vol.13 , pp. 305-314
    • Berk, B.C.1    Vekshtein, V.2    Gordon, H.M.3    Tsuda, T.4
  • 28
    • 0023916169 scopus 로고
    • Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
    • Geisterfer, A.A.; Peach, M.J.; Owens, G.K. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ. Res. 1988, 62, 749-756.
    • (1988) Circ. Res. , vol.62 , pp. 749-756
    • Geisterfer, A.A.1    Peach, M.J.2    Owens, G.K.3
  • 32
    • 0028175961 scopus 로고
    • Angiotensin receptor regulates cardiac hypertrophy and transforming growth factor-beta 1 expression
    • Everett, A.D.; Tufro-McReddie, A.; Fisher, A.; Gomez, R.A. Angiotensin receptor regulates cardiac hypertrophy and transforming growth factor-beta 1 expression. Hypertension 1994, 23, 587-592.
    • (1994) Hypertension , vol.23 , pp. 587-592
    • Everett, A.D.1    Tufro-McReddie, A.2    Fisher, A.3    Gomez, R.A.4
  • 33
    • 0027097869 scopus 로고
    • Mechanisms of cardiac growth. The role of the renin-angiotensin system
    • Fernandez-Alfonso, M.S.; Ganten, D.; Paul, M. Mechanisms of cardiac growth. The role of the renin-angiotensin system. Basic Res. Cardiol. 1992, 87, 173-181.
    • (1992) Basic Res. Cardiol. , vol.87 , pp. 173-181
    • Fernandez-Alfonso, M.S.1    Ganten, D.2    Paul, M.3
  • 34
    • 0028223429 scopus 로고
    • Angiotensin II alters aortic fibronectin independently of hypertension
    • Himeno, H.; Crawford, D.C.; Hosoi, M.; Chobanian, A.V.; Brecher, P. Angiotensin II alters aortic fibronectin independently of hypertension. Hypertension 1994, 23, 823-826.
    • (1994) Hypertension , vol.23 , pp. 823-826
    • Himeno, H.1    Crawford, D.C.2    Hosoi, M.3    Chobanian, A.V.4    Brecher, P.5
  • 35
    • 0028223036 scopus 로고
    • Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat
    • Crawford, D.C.; Chobanian, A.V.; Brecher, P. Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat. Circ. Res. 1994, 74, 727-739.
    • (1994) Circ. Res. , vol.74 , pp. 727-739
    • Crawford, D.C.1    Chobanian, A.V.2    Brecher, P.3
  • 36
    • 0034625073 scopus 로고    scopus 로고
    • Investigation into the sources of superoxide in human blood vessels: Angiotensin II increases superoxide production in human internal mammary arteries
    • Berry, C.; Hamilton, C.A.; Brosnan, M.J.; Magill, F.G.; Berg, G.A.; McMurray, J.J.; Dominiczak, A.F. Investigation into the sources of superoxide in human blood vessels: Angiotensin II increases superoxide production in human internal mammary arteries. Circulation 2000, 101, 2206-2212.
    • (2000) Circulation , vol.101 , pp. 2206-2212
    • Berry, C.1    Hamilton, C.A.2    Brosnan, M.J.3    Magill, F.G.4    Berg, G.A.5    McMurray, J.J.6    Dominiczak, A.F.7
  • 37
    • 3343005248 scopus 로고    scopus 로고
    • Hypertension caused by angiotensin II infusion involves increased superoxide production in the Central nervous system
    • Zimmerman, M.C.; Lazartigues, E.; Sharma, R.V.; Davisson, R.L. Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system. Circ. Res. 2004, 95, 210-216.
    • (2004) Circ. Res. , vol.95 , pp. 210-216
    • Zimmerman, M.C.1    Lazartigues, E.2    Sharma, R.V.3    Davisson, R.L.4
  • 38
    • 0042810670 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidases: Specific features, expression, and regulation
    • Lassegue, B.; Clempus, R.E. Vascular NAD(P)H oxidases: Specific features, expression, and regulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 285, 277-297.
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.285 , pp. 277-297
    • Lassegue, B.1    Clempus, R.E.2
  • 39
    • 53049093454 scopus 로고    scopus 로고
    • Role of reactive oxygen species in brainstem in neural mechanisms of hypertension
    • Hirooka, Y. Role of reactive oxygen species in brainstem in neural mechanisms of hypertension. Auton. Neurosci. 2008, 142, 20-24.
    • (2008) Auton. Neurosci. , vol.142 , pp. 20-24
    • Hirooka, Y.1
  • 40
    • 2542478969 scopus 로고    scopus 로고
    • Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men
    • Monahan, K.D.; Eskurza, I.; Seals, D.R. Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am. J. Physiol. Heart Circ. Physiol. 2004, 286, 2113-2117.
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.286 , pp. 2113-2117
    • Monahan, K.D.1    Eskurza, I.2    Seals, D.R.3
  • 41
    • 77951099337 scopus 로고    scopus 로고
    • Chronic antioxidant treatment improves arterial renovascular hypertension and oxidative stress markers in the kidney in wistar rats
    • Nishi, E.E.; Oliveira-Sales, E.B.; Bergamaschi, C.T.; Oliveira, T.G.; Boim, M.A.; Campos, R.R. Chronic antioxidant treatment improves arterial renovascular hypertension and oxidative stress markers in the kidney in Wistar rats. Am. J. Hypertens. 2010, 23, 473-480.
    • (2010) Am. J. Hypertens. , vol.23 , pp. 473-480
    • Nishi, E.E.1    Oliveira-Sales, E.B.2    Bergamaschi, C.T.3    Oliveira, T.G.4    Boim, M.A.5    Campos, R.R.6
  • 42
    • 0029797239 scopus 로고    scopus 로고
    • Oxygen-derived free radicals contribute to baroreceptor dysfunction in atherosclerotic rabbits
    • Li, Z.; Mao, H.Z.; Abboudm, F.M.; Chapleau, M.W. Oxygen-derived free radicals contribute to baroreceptor dysfunction in atherosclerotic rabbits. Circ. Res. 1996, 79, 802-811.
    • (1996) Circ. Res. , vol.79 , pp. 802-811
    • Li, Z.1    Mao, H.Z.2    Abboudm, F.M.3    Chapleau, M.W.4
  • 45
    • 48849114553 scopus 로고    scopus 로고
    • Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity
    • Shay, K.P.; Moreau, R.F.; Smith, E.J.; Smith, A.R.; Hagen, T.M. Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life 2008, 60, 362-367.
    • (2008) IUBMB Life , vol.60 , pp. 362-367
    • Shay, K.P.1    Moreau, R.F.2    Smith, E.J.3    Smith, A.R.4    Hagen, T.M.5
  • 46
    • 38949165231 scopus 로고    scopus 로고
    • NADPH oxidase CYBA polymorphisms oxidative stress and cardiovascular diseases
    • San Jose, G.; Fortuno, A.; Beloqui, O.; Diez, J.; Zalba, G. NADPH oxidase CYBA polymorphisms oxidative stress and cardiovascular diseases. Clin. Sci. (Lond.) 2008, 114, 173-182.
    • (2008) Clin. Sci. (Lond.) , vol.114 , pp. 173-182
    • San Jose, G.1    Fortuno, A.2    Beloqui, O.3    Diez, J.4    Zalba, G.5
  • 47
    • 77956497735 scopus 로고    scopus 로고
    • Beyond statin therapy: A review of the management of residual risk in diabetes mellitus
    • Judge, E.P.; Phelan, D.; O'Shea, D. Beyond statin therapy: A review of the management of residual risk in diabetes mellitus. J. R. Soc. Med. 2010, 103, 357-362.
    • (2010) J. R. Soc. Med. , vol.103 , pp. 357-362
    • Judge, E.P.1    Phelan, D.2    O'Shea, D.3
  • 49
    • 77952547838 scopus 로고    scopus 로고
    • Dietary salt enhances angiotensin-II-induced superoxide formation in the rostral ventrolateral medulla
    • Braga, V.A. Dietary salt enhances angiotensin-II-induced superoxide formation in the rostral ventrolateral medulla. Auton. Neurosci. Basic Clin. 2010, 155, 14-18.
    • (2010) Auton. Neurosci. Basic Clin. , vol.155 , pp. 14-18
    • Braga, V.A.1
  • 50
    • 57449084727 scopus 로고    scopus 로고
    • Cardiovascular responses to peripheral chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry
    • Braga, V.A.; Burmeister, M.A.; Sharma, R.V.; Davisson, R.L. Cardiovascular responses to peripheral chemoreflex activation and comparison of different methods to evaluate baroreflex gain in conscious mice using telemetry. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 295, 1168-1174.
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.295 , pp. 1168-1174
    • Braga, V.A.1    Burmeister, M.A.2    Sharma, R.V.3    Davisson, R.L.4


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