Sildenafil restores endothelial function in the apolipoprotein E knockout mouse

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Balarini, Camille M ^a   Leal, Marcos A ^b   Gomes, Isabele B S ^a   Pereira, Thiago M C ^c,d   Gava, Agata L ^a   Meyrelles, Silvana S ^a   Vasquez, Elisardo C ^a,b  

^a FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

^b Escola Superior de Ciencias da Santa Casa de Misericordia de Vitoria   (Brazil)

^c Federal Institute of Education   (Brazil)

^d UNIVERSIDADE VILA VELHA   (Brazil)

Author keywords

ApoE knockout mice; Atherosclerosis; cGMP; Endothelial dysfunction; Nitric oxide; Oxidative stress; PDE5; Sildenafil

Indexed keywords

ACETYLCHOLINE; APOCYNIN; APOLIPOPROTEIN E; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SILDENAFIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; HYPERCHOLESTEROLEMIA; MALE; MORPHOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TREATMENT DURATION; TREATMENT RESPONSE; VASODILATATION; WILD TYPE;

ACETOPHENONES; ANIMALS; APOLIPOPROTEINS E; ENDOTHELIUM, VASCULAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PIPERAZINES; PURINES; REACTIVE OXYGEN SPECIES; SULFONES;

EID: 84871739804     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-3     Document Type: Article

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