A small molecule nanodrug consisting of amphiphilic targeting ligand-chemotherapy drug conjugate for targeted cancer therapy

Journal of Controlled Release

Volumn 230, Issue , 2016, Pages 34-44

  Mou, Quanbing ^a   Ma, Yuan ^a   Zhu, Xinyuan ^a   Yan, Deyue ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Amphiphilic self assembly; Cancer therapy; Small molecule nanodrugs; Targeted delivery

Indexed keywords

CARDIOVASCULAR SYSTEM; CHEMOTHERAPY; DISEASES; LIGANDS; MOLECULES; NANOPARTICLES; ONCOLOGY; SELF ASSEMBLY;

AMPHIPHILICS; BATCH-TO-BATCH VARIATIONS; CANCER THERAPY; NANODRUGS; TARGETED CANCER THERAPY; TARGETED DELIVERY; TARGETED DELIVERY SYSTEMS; WELL-DEFINED STRUCTURES;

DRUG THERAPY;

DOXORUBICIN; HYDRAZONE DERIVATIVE; LACTOSE; NANOCARRIER; NANOPARTICLE; ANTINEOPLASTIC ANTIBIOTIC; BETA-GLUCONO-1,5-LACTONE; DISACCHARIDE; GLUCONIC ACID; LACTOBIONIC ACID; LACTONE; LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CIRCULATION TIME; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; RAT; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; HUMAN; KIDNEY; LIVER; METABOLISM; NEOPLASM; NUDE MOUSE; PATHOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DISACCHARIDES; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; GLUCONATES; HUMANS; KIDNEY; LACTONES; LIGANDS; LIVER; MALE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; NEOPLASMS; RATS, SPRAGUE-DAWLEY; TUMOR BURDEN;

EID: 84962711928     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.03.037     Document Type: Article

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