Prodrugs forming high drug loading multifunctional nanocapsules for intracellular cancer drug delivery

Journal of the American Chemical Society

Volumn 132, Issue 12, 2010, Pages 4259-4265

  Shen, Youqing ^a,b   Jin, Erlei ^b   Zhang, Bo ^b   Murphy, Caitlin J ^c   Sui, Meihua ^a   Zhao, Jian ^a   Wang, Jinqiang ^a   Tang, Jianbin ^a   Fan, Maohong ^b   Van Kirk, Edward ^c   Murdoch, William J ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF WYOMING   (United States)

^c UNIVERSITY OF WYOMING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTICANCER DRUG; AQUEOUS SOLUTIONS; BURST RELEASE; CANCER CELLS; CANCER DRUG; CARRIER MATERIAL; DOXORUBICIN; DRUG LOADING; DRUG MOLECULES; HIGH LOADINGS; IN-VITRO; INERT MATERIALS; NANOCARRIERS; NANOMEDICINES; NEW CONCEPT; OLIGOMER CHAINS; PRODRUGS; WATER SOLUBLE DRUGS;

CHARGE TRAPPING; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; HOT CARRIERS; NANOCAPSULES; PHOSPHOLIPIDS;

LOADING;

AMPHOPHILE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DOXORUBICIN; DRUG CARRIER; ETHYLENE GLYCOL; LIPOSOME; NANOCAPSULE; NANOCARRIER; OLIGOMER; PHOSPHOLIPID; PRODRUG; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULE; MOUSE; NANOFABRICATION; NONHUMAN; PRODUCTIVITY; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; NANOCAPSULES; NEOPLASMS; PRODRUGS;

EID: 77950248056     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja909475m     Document Type: Article

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