Combination of small molecule prodrug and nanodrug delivery: Amphiphilic drug-drug conjugate for cancer therapy

Journal of the American Chemical Society

Volumn 136, Issue 33, 2014, Pages 11748-11756

  Huang, Ping ^a   Wang, Dali ^a   Su, Yue ^a   Huang, Wei ^a   Zhou, Yongfeng ^a   Cui, Daxiang ^a   Zhu, Xinyuan ^a   Yan, Deyue ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DELIVERY; DRUG PRODUCTS; ESTERIFICATION; ESTERS; HYDROPHILICITY; HYDROPHOBICITY; IRIDIUM; NANOPARTICLES; TUMORS;

ANTICANCER ACTIVITIES; ANTICANCER DRUG; CELLULAR INTERNALIZATION; CELLULAR UPTAKE; DRUG DELIVERY SYSTEM; HYDROPHILIC AND HYDROPHOBIC; MULTIDRUG RESISTANCE; SMALL MOLECULES;

ONCOLOGY;

AMPHOPHILE; CHLORAMBUCIL; IRINOTECAN; NANOPARTICLE; PRODRUG; IRIDIUM; MOLECULAR LIBRARY; ORGANOMETALLIC COMPOUND; SURFACTANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER THERAPY; CELL TRANSPORT; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; HUMAN; HUMAN CELL; HYDROLYSIS; INTERNALIZATION; NONHUMAN; RAT; ADMINISTRATION AND DOSAGE; ANIMAL; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF 7 CELL LINE; MOLECULAR LIBRARY; MOUSE; MULTIDRUG RESISTANCE; NUDE MOUSE; PATHOLOGY; PHARMACOLOGY; PROCEDURES; SYNTHESIS;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; CHLORAMBUCIL; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; IRIDIUM; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF-7 CELLS; MICE; MICE, NUDE; MOLECULAR STRUCTURE; NANOPARTICLES; ORGANOMETALLIC COMPOUNDS; PRODRUGS; RATS; SMALL MOLECULE LIBRARIES; SURFACE-ACTIVE AGENTS;

EID: 84906351138     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja505212y     Document Type: Article

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