-
1
-
-
0021908189
-
Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: Pronounced improvements in pharmacological properties
-
Maeda, H., Ueda, M., Morinaga, T. & Matsumoto, T. Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: pronounced improvements in pharmacological properties. J. Med. Chem. 28, 455-461 (1985).
-
(1985)
J. Med. Chem.
, vol.28
, pp. 455-461
-
-
Maeda, H.1
Ueda, M.2
Morinaga, T.3
Matsumoto, T.4
-
2
-
-
0035291191
-
Smancs and polymer-conjugated macromolecular drugs: Advantages in cancer chemotherapy
-
Maeda, H. SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Adv. Drug Deliv. Rev. 46, 169-185 (2001).
-
(2001)
Adv. Drug Deliv. Rev.
, vol.46
, pp. 169-185
-
-
Maeda, H.1
-
3
-
-
84865142752
-
Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation
-
Osada, K. et al. Bioactive polymeric metallosomes self-assembled through block copolymer-metal complexation. J. Am. Chem. Soc. 134, 13172-13175 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13172-13175
-
-
Osada, K.1
-
4
-
-
12344269847
-
Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy
-
Bae, Y. et al. Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy. Bioconjug. Chem. 16, 122-130 (2005).
-
(2005)
Bioconjug. Chem.
, vol.16
, pp. 122-130
-
-
Bae, Y.1
-
5
-
-
33745703563
-
Polymer therapeutics: Concepts and applications
-
Haag, R. & Kratz, F. Polymer therapeutics: concepts and applications. Angew. Chem. Int. Ed. 45, 1198-1215 (2006).
-
(2006)
Angew. Chem. Int. Ed.
, vol.45
, pp. 1198-1215
-
-
Haag, R.1
Kratz, F.2
-
6
-
-
67749143922
-
Expansile nanoparticles: Synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system
-
Griset, A. P. et al. Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system. J. Am. Chem. Soc. 131, 2469-2471 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 2469-2471
-
-
Griset, A.P.1
-
7
-
-
13644257605
-
Delivery platform for hydrophobic drugs: Prodrug approach combined with self-assembled multilayers
-
Thierry, B. et al. Delivery platform for hydrophobic drugs: prodrug approach combined with self-assembled multilayers. J. Am. Chem. Soc. 127, 1626-1627 (2005).
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 1626-1627
-
-
Thierry, B.1
-
8
-
-
54549097056
-
Conjugated chitosan as a novel platform for oral delivery of paclitaxel
-
Lee, E. et al. Conjugated chitosan as a novel platform for oral delivery of paclitaxel. J. Med. Chem. 51, 6442-6449 (2008).
-
(2008)
J. Med. Chem.
, vol.51
, pp. 6442-6449
-
-
Lee, E.1
-
9
-
-
72449141425
-
Heparin-paclitaxel conjugates as drug delivery system: Synthesis, self-assembly property, drug release, and antitumor activity
-
Wang, Y., Xin, D., Liu, K., Zhu, M. & Xiang, J. Heparin-paclitaxel conjugates as drug delivery system: synthesis, self-assembly property, drug release, and antitumor activity. Bioconjug. Chem. 20, 2214-2221 (2009).
-
(2009)
Bioconjug. Chem.
, vol.20
, pp. 2214-2221
-
-
Wang, Y.1
Xin, D.2
Liu, K.3
Zhu, M.4
Xiang, J.5
-
10
-
-
2942685195
-
Synthesis physico-chemical and biological characterization of a paclitaxel macromolecular prodrug
-
Cavallaro, G., Licciardi, M., Caliceti, P., Salmaso, S. & Giammona, G. Synthesis, physico-chemical and biological characterization of a paclitaxel macromolecular prodrug. Eur. J. Pharm. Biopharm. 58, 151-159 (2004).
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 151-159
-
-
Cavallaro, G.1
Licciardi, M.2
Caliceti, P.3
Salmaso, S.4
Giammona, G.5
-
11
-
-
33846490802
-
A novel polymer-paclitaxel conjugate based on amphiphilic triblock copolymer
-
Xie, Z. et al. A novel polymer-paclitaxel conjugate based on amphiphilic triblock copolymer. J. Control. Release 117, 210-216 (2007).
-
(2007)
J. Control. Release
, vol.117
, pp. 210-216
-
-
Xie, Z.1
-
12
-
-
0142119372
-
Design of environmentsensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change
-
Bae, Y., Fukushima, S., Harada, A. & Kataoka, K. Design of environmentsensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. Angew. Chem. Int. Ed. 42, 4640-4643 (2003).
-
(2003)
Angew. Chem. Int. Ed.
, vol.42
, pp. 4640-4643
-
-
Bae, Y.1
Fukushima, S.2
Harada, A.3
Kataoka, K.4
-
13
-
-
10444279209
-
Cyclodextrin-based pharmaceutics: Past, present and future
-
Davis, M. E. & Brewster, M. E. Cyclodextrin-based pharmaceutics: past, present and future. Nat. Rev. Drug Discov. 3, 1023-1035 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 1023-1035
-
-
Davis, M.E.1
Brewster, M.E.2
-
14
-
-
34548134519
-
Cyclodextrins as pharmaceutical solubilizers
-
Brewster, M. E. & Loftsson, T. Cyclodextrins as pharmaceutical solubilizers. Adv. Drug Deliv. Rev. 59, 645-666 (2007).
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
, pp. 645-666
-
-
Brewster, M.E.1
Loftsson, T.2
-
15
-
-
0029819323
-
Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization
-
Loftsson, T. & Brewster, M. E. Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization. J. Pharm. Sci. 85, 1017-1025 (1996).
-
(1996)
J. Pharm. Sci.
, vol.85
, pp. 1017-1025
-
-
Loftsson, T.1
Brewster, M.E.2
-
16
-
-
70349847279
-
Tuning the interactions in cyclodextrin polymer nanoassemblies
-
Layre, A. M., Wintgens, V., Gosselet, N. M., Dalmas, F. & Amiel, C. Tuning the interactions in cyclodextrin polymer nanoassemblies. Eur. Polym. J. 45, 3016-3026 (2009).
-
(2009)
Eur. Polym. J.
, vol.45
, pp. 3016-3026
-
-
Layre, A.M.1
Wintgens, V.2
Gosselet, N.M.3
Dalmas, F.4
Amiel, C.5
-
17
-
-
68749108024
-
Self-assembling microparticles with controllable disruption properties based on cyclodextrin interactions
-
Nielsen, A. L., Steffensen, K. & Larsen, K. L. Self-assembling microparticles with controllable disruption properties based on cyclodextrin interactions. Colloids Surf. B 73, 267-275 (2009).
-
(2009)
Colloids Surf. B
, vol.73
, pp. 267-275
-
-
Nielsen, A.L.1
Steffensen, K.2
Larsen, K.L.3
-
18
-
-
33845508580
-
Paclitaxel prodrugs: Toward smarter delivery of anticancer agents
-
Skwarczynski, M., Hayashi, Y. & Kiso, Y. Paclitaxel prodrugs: toward smarter delivery of anticancer agents. J. Med. Chem. 49, 7253-7269 (2006).
-
(2006)
J. Med. Chem.
, vol.49
, pp. 7253-7269
-
-
Skwarczynski, M.1
Hayashi, Y.2
Kiso, Y.3
-
19
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan, M. A. & Wilson, L. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4, 253-265 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
20
-
-
0034880214
-
The drawbacks and advantages of vehicle selection for drug formulation
-
Gelderblom, H., Verweij, J., Nooter, K. & Sparreboom, A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur. J. Cancer 37, 1590-1598 (2001).
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 1590-1598
-
-
Gelderblom, H.1
Verweij, J.2
Nooter, K.3
Sparreboom Cremophor A, E.L.4
-
21
-
-
0037124197
-
Preparation, characterization, molecular modelling and in vitro activity of paclitaxel-cyclodextrin complexes
-
Alcaro, S. et al. Preparation, characterization, molecular modelling and in vitro activity of paclitaxel-cyclodextrin complexes. Bioorg. Med. Chem. Lett. 12, 1637-1641 (2002).
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 1637-1641
-
-
Alcaro, S.1
-
22
-
-
0142124208
-
Inclusion complexation and solubilization of paclitaxel by bridged bis(b-cyclodextrin)s containing a tetraethylenepentaamino spacer
-
Liu, Y. et al. Inclusion complexation and solubilization of paclitaxel by bridged bis(b-cyclodextrin)s containing a tetraethylenepentaamino spacer. J. Med. Chem. 46, 4634-4637 (2003).
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4634-4637
-
-
Liu, Y.1
-
23
-
-
33751247035
-
Enhancement of water-solubility and bioactivity of paclitaxel using modified cyclodextrins
-
Hamada, H., Ishihara, K., Masuoka, N., Mikuni, K. & Nakajima, N. Enhancement of water-solubility and bioactivity of paclitaxel using modified cyclodextrins. J. Biosci. Bioeng. 102, 369-371 (2006).
-
(2006)
J. Biosci. Bioeng.
, vol.102
, pp. 369-371
-
-
Hamada, H.1
Ishihara, K.2
Masuoka, N.3
Mikuni, K.4
Nakajima, N.5
-
24
-
-
78650090366
-
Inclusion of chemotherapeutic agents in substituted b-cyclodextrin derivatives
-
Thiele, C., Auerbach, D., Jung, G. & Wenz, G. Inclusion of chemotherapeutic agents in substituted b-cyclodextrin derivatives. J. Incl. Phenom. Macrocycl. Chem. 69, 303-307 (2011).
-
(2011)
J. Incl. Phenom. Macrocycl. Chem.
, vol.69
, pp. 303-307
-
-
Thiele, C.1
Auerbach, D.2
Jung, G.3
Wenz, G.4
-
25
-
-
80052332175
-
Leading neuroblastoma cells to die by multiple premeditated attacks from a multifunctionalized nanoconstruct
-
Jiao, P. et al. Leading neuroblastoma cells to die by multiple premeditated attacks from a multifunctionalized nanoconstruct. J. Am. Chem. Soc. 113, 13918-13921 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.113
, pp. 13918-13921
-
-
Jiao, P.1
-
26
-
-
4143063646
-
Optimizing saccharide-directed molecular delivery to biological receptors: Design, synthesis, and biological evaluation of glycodendrimer- cyclodextrin conjugates
-
Benito, J. M. et al. Optimizing saccharide-directed molecular delivery to biological receptors: design, synthesis, and biological evaluation of glycodendrimer-cyclodextrin conjugates. J. Am. Chem. Soc. 126, 10355-10363 (2004).
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 10355-10363
-
-
Benito, J.M.1
-
27
-
-
0142050953
-
Taxol inclusion complexes with a cyclodextrin dimer: Possibilities to detoxify chemotherapeutics and to target drugs specifically to tumors
-
Moser, J. G., Rose, I., Wagner, B., Wieneke, T. & Vervoorts, A. Taxol inclusion complexes with a cyclodextrin dimer: possibilities to detoxify chemotherapeutics and to target drugs specifically to tumors J. Incl. Phenom. Macrocycl. Chem. 39, 13-18 (2001).
-
(2001)
J. Incl. Phenom. Macrocycl. Chem.
, vol.39
, pp. 13-18
-
-
Moser, J.G.1
Rose, I.2
Wagner, B.3
Wieneke, T.4
Vervoorts, A.5
-
28
-
-
0030642478
-
Dimeric cyclodextrin carriers with high binding affinity to porphyrinoid photosensitizers
-
Ruebner, A. et al. Dimeric cyclodextrin carriers with high binding affinity to porphyrinoid photosensitizers. J. Incl. Phenom. Mol. Recognit. Chem. 27, 69-84 (1997).
-
(1997)
J. Incl. Phenom. Mol. Recognit. Chem.
, vol.27
, pp. 69-84
-
-
Ruebner, A.1
-
29
-
-
33846880687
-
Rupturing polymeric micelles with cyclodextrins
-
Joseph, J., Dreiss, C. A. & Cosgrove, T. Rupturing polymeric micelles with cyclodextrins. Langmuir. 23, 460-466 (2007).
-
(2007)
Langmuir.
, vol.23
, pp. 460-466
-
-
Joseph, J.1
Dreiss, C.A.2
Cosgrove, T.3
-
30
-
-
77954248346
-
Self-assembled nanogel made of mannan: Synthesis and characterization
-
Ferreira, S. A., Coutinho, P. J. G. & Gama, F. M. Self-assembled nanogel made of mannan: synthesis and characterization. Langmuir. 26, 11413-11420 (2010).
-
(2010)
Langmuir.
, vol.26
, pp. 11413-11420
-
-
Ferreira, S.A.1
Coutinho, P.J.G.2
Gama, F.M.3
-
31
-
-
70349937876
-
A coarse-grained model for polyethylene oxide and polyethylene glycol: Conformation and hydrodynamics
-
Lee, H., De Vries, A. H., Marrink, S.-J. & Pastor, R. W. A coarse-grained model for polyethylene oxide and polyethylene glycol: conformation and hydrodynamics. J. Phys. Chem. B 113, 13186-13194 (2009).
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 13186-13194
-
-
Lee, H.1
De Vries, A.H.2
Marrink, S.-J.3
Pastor, R.W.4
-
32
-
-
33847730775
-
Synthesis of novel supramolecular assemblies based on hyaluronic acid derivatives bearing bivalent b-cyclodextrin and adamantane moieties
-
Charlot, A. & Auzely-Velty, R. Synthesis of novel supramolecular assemblies based on hyaluronic acid derivatives bearing bivalent b-cyclodextrin and adamantane moieties. Macromolecules 40, 1147-1158 (2007).
-
(2007)
Macromolecules
, vol.40
, pp. 1147-1158
-
-
Charlot, A.1
Auzely-Velty, R.2
-
33
-
-
38349098456
-
Novel hyaluronic acid based supramolecular assemblies stabilized by multivalent specific interactions: Rheological behavior in aqueous solution
-
Charlot, A. & Auzely-Velty, R. Novel hyaluronic acid based supramolecular assemblies stabilized by multivalent specific interactions: rheological behavior in aqueous solution. Macromolecules 40, 9555-9563 (2007).
-
(2007)
Macromolecules
, vol.40
, pp. 9555-9563
-
-
Charlot, A.1
Auzely-Velty, R.2
-
34
-
-
84863726268
-
Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction
-
Flores, M. L. et al. Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction. Breast Cancer Res. Treat. 133, 917-928 (2012).
-
(2012)
Breast Cancer Res. Treat.
, vol.133
, pp. 917-928
-
-
Flores, M.L.1
-
35
-
-
0034151778
-
Human breast carcinoma cell express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-pseudomonas exotoxin fusion protein in vitro and in vivo
-
Leland, P. et al. Human breast carcinoma cell express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-pseudomonas exotoxin fusion protein in vitro and in vivo. Mol. Med. 6, 165-178 (2000).
-
(2000)
Mol. Med.
, vol.6
, pp. 165-178
-
-
Leland, P.1
-
36
-
-
84884921607
-
Designed nanocage displaying ligand-specific peptide bunches for high affinity and biological activity
-
Jeon, J. O. et al. Designed nanocage displaying ligand-specific peptide bunches for high affinity and biological activity. ACS Nano 7, 7462-7471 (2013).
-
(2013)
ACS Nano
, vol.7
, pp. 7462-7471
-
-
Jeon, J.O.1
-
37
-
-
84862305857
-
Treating glioblastoma multiforme with selective high-dose liposomal doxorubicin chemotherapy induced by repeated focused ultrasound
-
Yang, F. Y. et al. Treating glioblastoma multiforme with selective high-dose liposomal doxorubicin chemotherapy induced by repeated focused ultrasound. Int. J. Nanomedicine 7, 965-974 (2012).
-
(2012)
Int. J. Nanomedicine
, vol.7
, pp. 965-974
-
-
Yang, F.Y.1
-
38
-
-
79953112735
-
Preclinical and clinical studies of NK012, an SN-38-incorporating polymeric micelles, which is designed based on EPR effect
-
Matsumura, Y. Preclinical and clinical studies of NK012, an SN-38-incorporating polymeric micelles, which is designed based on EPR effect. Adv. Drug Deliv. Rev. 63, 184-192 (2011).
-
(2011)
Adv. Drug Deliv. Rev.
, vol.63
, pp. 184-192
-
-
Matsumura, Y.1
-
39
-
-
0141458033
-
Synthesis of linear, b-cyclodextrin-based polymers and their camptothecin conjugates
-
Cheng, J., Khin, K. T., Jensen, G. S., Liu, A. & Davis, M. E. Synthesis of linear, b-cyclodextrin-based polymers and their camptothecin conjugates. Bioconjug. Chem. 14, 1007-1017 (2003).
-
(2003)
Bioconjug. Chem.
, vol.14
, pp. 1007-1017
-
-
Cheng, J.1
Khin, K.T.2
Jensen, G.S.3
Liu, A.4
Davis, M.E.5
-
40
-
-
70349992906
-
Design and development of IT-101, a cyclodextrin-containing polymer conjugate of camptothecin
-
Davis, M. E. Design and development of IT-101, a cyclodextrin-containing polymer conjugate of camptothecin. Adv. Drug Deliv. Rev. 61, 1189-1192 (2009).
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 1189-1192
-
-
Davis, M.E.1
-
41
-
-
0025328330
-
A convenient method for functionalization of the 2-position of cyclodextrins
-
Rong, D. & DSouza, V. T. A convenient method for functionalization of the 2-position of cyclodextrins. Tetrahedron Lett. 31, 4275-4278 (1990).
-
(1990)
Tetrahedron Lett.
, vol.31
, pp. 4275-4278
-
-
Rong, D.1
Dsouza, V.T.2
-
42
-
-
13644279577
-
Synthesis of a novel linear water-soluble b-cyclodextrin polymer
-
Renard, E., Volet, G. & Amiel, C. Synthesis of a novel linear water-soluble b-cyclodextrin polymer. Polym. Int. 54, 594-599 (2005).
-
(2005)
Polym. Int.
, vol.54
, pp. 594-599
-
-
Renard, E.1
Volet, G.2
Amiel, C.3
-
43
-
-
59749094242
-
H sensitive supramolecular assembling system between a new linear water soluble b-cyclodextrin terpolymer and an amphiphilic poly(ethylene oxide)
-
Volet, G. & Amiel, C. pH sensitive supramolecular assembling system between a new linear water soluble b-cyclodextrin terpolymer and an amphiphilic poly(ethylene oxide). Eur. Polym. J. 45, 852-862 (2009).
-
(2009)
Eur. Polym. J.
, vol.45
, pp. 852-862
-
-
Volet, G.1
Amiel, C.2
-
44
-
-
0030491443
-
Cyclodextrin sidechain polyesters-synthesis and inclusion of adamantan derivatives
-
Weickenmeier, M. & Wenz, G. Cyclodextrin sidechain polyesters-synthesis and inclusion of adamantan derivatives. Macromol. Rapid Commun. 17, 731-736 (1996).
-
(1996)
Macromol. Rapid Commun.
, vol.17
, pp. 731-736
-
-
Weickenmeier, M.1
Wenz, G.2
-
45
-
-
84864313078
-
A poly(g, L-glutamic acid)-citric acid based nanoconjugate for cisplatin delivery
-
Xiong, Y. et al. A poly(g, L-glutamic acid)-citric acid based nanoconjugate for cisplatin delivery. Biomaterials 33, 7182-7193 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 7182-7193
-
-
Xiong, Y.1
|