In vivo delivery of transcription factors with multifunctional oligonucleotides

Nature Materials

Volumn 14, Issue 7, 2015, Pages 701-706

  Lee, Kunwoo ^a,b   Rafi, Mohammad ^a   Wang, Xiaojian ^a   Aran, Kiana ^a   Feng, Xuli ^a   Lo Sterzo, Carlo ^a   Tang, Richard ^a   Lingampalli, Nithya ^a   Kim, Hyun Jin ^a   Murthy, Niren ^a,b  

^a University of California   (United States)

^b UC Berkeley Graduate Group in Bioengineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROPHOBICITY; MOLECULAR BIOLOGY; OLIGONUCLEOTIDES; TOXICITY; TRANSCRIPTION FACTORS;

ACIDIC ENVIRONMENT; DELIVERY PROBLEMS; ENDOSOMAL DISRUPTION; GALACTOSE RESIDUES; HYDROPHOBIC DOMAINS; HYDROPHOBIC MEMBRANE; MOLECULAR ARCHITECTURE; TRANSCRIPTION FACTOR BINDING;

TRANSCRIPTION;

ALANINE AMINOTRANSFERASE; DNA; NFE2L2 PROTEIN, MOUSE; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2;

ANIMAL; CHEMISTRY; CYTOLOGY; DRUG DELIVERY SYSTEM; ENDOSOME; HEP-G2 CELL LINE; HUMAN; HYDROLYSIS; LIVER; LIVER CELL; METABOLISM; MOUSE; OXIDATIVE STRESS; PH; SPECTROFLUOROMETRY; TISSUE DISTRIBUTION;

ALANINE TRANSAMINASE; ANIMALS; DNA; DRUG DELIVERY SYSTEMS; ENDOSOMES; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LIVER; MICE; NF-E2-RELATED FACTOR 2; OLIGONUCLEOTIDES; OXIDATIVE STRESS; SPECTROMETRY, FLUORESCENCE; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

EID: 84931957742     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat4269     Document Type: Article

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