Enzyme-responsive amphiphilic PEG-dendron hybrids and their assembly into smart micellar nanocarriers

Journal of the American Chemical Society

Volumn 136, Issue 21, 2014, Pages 7531-7534

  Harnoy, Assaf J ^a   Rosenbaum, Ido ^a   Tirosh, Einat ^a   Ebenstein, Yuval ^a   Shaharabani, Rona ^a   Beck, Roy ^a   Amir, Roey J ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DENDRIMERS; DRUG DELIVERY; ENZYMES; MICELLES; POLYETHYLENE OXIDES;

AMPHIPHILIC BLOCK COPOLYMERS; DETAILED KINETICS; HIGH SELECTIVITY; MODULAR DESIGNS; MOLECULAR MECHANISM; MONO-DISPERSE; NANOCONTAINERS; STIMULI-RESPONSIVE;

POLYETHYLENE GLYCOLS;

AMPHOPHILE; COPOLYMER; ENZYME; MACROGOL; NANOCARRIER; AMIDASE; DENDRIMER; MACROGOL DERIVATIVE; MICELLE; NANOMATERIAL; SURFACTANT;

ARTICLE; CHEMICAL REACTION KINETICS; DRUG DELIVERY SYSTEM; ENCAPSULATION; ENZYME ACTIVATION; HYBRID; HYDROPHILICITY; HYDROPHOBICITY; MICELLE; SYNTHESIS; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM;

AMIDOHYDROLASES; DENDRIMERS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICELLES; MOLECULAR STRUCTURE; NANOSTRUCTURES; POLYETHYLENE GLYCOLS; SURFACE-ACTIVE AGENTS;

EID: 84899575029     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja413036q     Document Type: Article

References (22)

1. Mai, Y.; Eisenberg, A. Chem. Soc. Rev. 2012, 41, 5969
2. Kataoka, K.; Harada, A.; Nagasaki, Y. Adv. Drug Delivery Rev. 2012, 64, 37
3. Rösler, A.; Vandermeulen, G.; Klok, H.-A. Adv. Drug Delivery Rev. 2012, 64, 270
4. Roy, D.; Cambre, J. N.; Sumerlin, B. S. Prog. Polym. Sci. 2010, 35, 278
5. Lundberg, P.; Lynd, N.; Zhang, Y.; Zeng, X.; Krogstad, D.; Paffen, T.; Malkoch, M.; Nyström, A.; Hawker, C. Soft Matter 2013, 9, 82
6. Gillies, E. R.; Jonsson, T. B.; Frechet, J. M. J. J. Am. Chem. Soc. 2004, 126, 11936
7. Lee, H.; Lee, J.; Poon, Z.; Hammond, P. Chem. Commun. 2008, 3726
8. Andre, X.; Zhang, M.; Mueller, A. Macromol. Rapid Commun. 2005, 26, 558
9. Lee, H.-I.; Wu, W.; Oh, J. K.; Mueller, L.; Sherwood, G.; Peteanu, L.; Kowalewski, T.; Matyjaszewski, K. Angew. Chem., Int. Ed. 2007, 46, 2453
10. Muraoka, T.; Koh, C.-Y.; Cui, H.; Stupp, S. I. Angew. Chem., Int. Ed. 2009, 48, 5946
11. Loh, X.; del Barrio, J. S.; Toh, P.; Lee, T.-C.; Jiao, D.; Rauwald, U.; Appel, E.; Scherman, O. Biomacromolecules 2011, 13, 84
12. Zelzer, M.; Todd, S. J.; Hirst, A. R.; McDonald, T. O.; Ulijn, R. V. Biomater. Sci. 2013, 1, 11
13. Ku, T.-H.; Chien, M.-P.; Thompson, M. P.; Sinkovits, R. S.; Olson, N. H.; Baker, T. S.; Gianneschi, N. C. J. Am. Chem. Soc. 2011, 133, 8392
14. Amir, R. J.; Zhong, S.; Pochan, D. J.; Hawker, C. J. J. Am. Chem. Soc. 2009, 131, 13949
15. Rao, J.; Khan, A. J. Am. Chem. Soc. 2013, 135, 14056
16. Gitsov, I. J. Polym. Sci., Part A: Polym. Chem. 2008, 46, 5295
17. Amir, R. J.; Danieli, E.; Shabat, D. Chem.-Eur. J. 2007, 13, 812
18. Dijkgraaf, I.; Anneloes, R. Y.; Soede, A.; Annemarie, D. C.; van Esse, G. W.; Brouwer, A. J.; Corstens, F. H. M.; Boerman, O. C.; Rijkers, D. T. S.; Liskamp, R. M. J. Org. Biomol. Chem. 2007, 5, 935
19. Fairbanks, B. D.; Sims, E. A.; Anseth, K. S.; Bowman, C. N. Macromolecules 2010, 43, 4113
20. Leenders, C. M. A.; Albertazzi, L.; Mes, T.; Koenigs, M. M. E.; Palmans, R. A.; Meijer, E. W. Chem. Commun. 2013, 49, 33
21. Yesilyurt, V.; Ramireddy, R.; Thayumanavan, S. Angew. Chem., Int. Ed. 2011, 50, 3038
22. Raghupathi, K.; Azagarsamy, M.; Thayumanavan, S. Chem.-Eur. J. 2011, 17, 11752