Local retention of antibodies in vivo with an injectable film embedded with a fluorogen-activating protein

Journal of Controlled Release

Volumn 230, Issue , 2016, Pages 1-12

  Liu, Wen ^a   Saunders, Matthew J ^b,f   Bagia, Christina ^a   Freeman, Eric C ^c   Fan, Yong ^b,d   Gawalt, Ellen S ^a,e   Waggoner, Alan S ^b   Meng, Wilson S ^a  

^a DUQUESNE UNIVERSITY   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c University of Georgia   (United States)

^d ALLEGHENY SINGER RESEARCH INSTITUTE   (United States)

^e MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^f Glycosensors and Diagnostics   (United States)

Author keywords

Antibody formulation; Bioaffinity film; Controlled release; Dimerized light chain 5 (dL5); Draining lymph nodes; EAK16; Fluorescent imaging; Fluorogen activating protein; Mathematical simulation; Self assembling peptide; Single chain variable fragment

Indexed keywords

BINDING SITES; BINS; CHAINS; CHEMICAL ACTIVATION; FLUORESCENCE; PEPTIDES; PROTEINS; TITRATION;

BIOAFFINITY; CONTROLLED RELEASE; EAK16; FLUORESCENT IMAGING; LIGHT CHAIN; LYMPH NODE; MATHEMATICAL SIMULATIONS; SELF-ASSEMBLING PEPTIDES; SINGLE CHAIN VARIABLE FRAGMENTS;

ANTIBODIES;

BETA FIBRILLIZING PEPTIDE; FLUOROGEN ACTIVATING PROTEIN; IMMUNOGLOBULIN G; MALACHITE GREEN; PEPTIDE; PROTEIN; PROTEIN A; PROTEIN G; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; FLUORESCENT DYE; FUCHSINE; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANTIBODY COMBINING SITE; ARTICLE; BETA SHEET; BIOCOMPATIBILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY DEVICE; DRUG DISTRIBUTION; DRUG RETENTION; GIANT CELL; IN VITRO STUDY; IN VIVO STUDY; INJECTABLE FILM; LYMPH VESSEL; MACROPHAGE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; QUANTUM YIELD; SUSTAINED DRUG RELEASE; VISCOMETRY; ANIMAL; BAGG ALBINO MOUSE; BINDING SITE; DRUG DELIVERY SYSTEM; FEMALE; INJECTION;

ANIMALS; BINDING SITES; DRUG DELIVERY SYSTEMS; FEMALE; FLUORESCENT DYES; IMMUNOGLOBULIN G; INJECTIONS; MICE, INBRED BALB C; PEPTIDES; PROTEIN BINDING; ROSANILINE DYES;

EID: 84962702972     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.03.032     Document Type: Article

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