-
1
-
-
85047696843
-
Monoclonal antibodies: the story of a discovery that revolutionized science and medicine
-
15040588
-
S.S.Alkan. Monoclonal antibodies: the story of a discovery that revolutionized science and medicine. Nat Rev Immunol 2004; 4:153-6; PMID:15040588; dx.doi.org/10.1038/nri1265
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 153-156
-
-
Alkan, S.S.1
-
2
-
-
77951614830
-
Monoclonal antibodies: versatile platforms for cancer immunotherapy
-
20414205
-
L.M.Weiner, R.Surana, S.Wang. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol 2010; 10:317-27; PMID:20414205; dx.doi.org/10.1038/nri2744
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 317-327
-
-
Weiner, L.M.1
Surana, R.2
Wang, S.3
-
3
-
-
84899112560
-
Trial watch: immunostimulatory monoclonal antibodies in cancer therapy
-
24701370
-
F.Aranda, E.Vacchelli, A.Eggermont, J.Galon, W.H.Fridman, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: immunostimulatory monoclonal antibodies in cancer therapy. Oncoimmunology 2014; 3:e27297; PMID:24701370; dx.doi.org/10.4161/onci.27297
-
(2014)
Oncoimmunology
, vol.3
, pp. 27297
-
-
Aranda, F.1
Vacchelli, E.2
Eggermont, A.3
Galon, J.4
Fridman, W.H.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
4
-
-
84921398753
-
Novel immune checkpoint blocker approved for the treatment of advanced melanoma
-
in press
-
L.Galluzzi, G.Kroemer, A.Eggermont. Novel immune checkpoint blocker approved for the treatment of advanced melanoma. Oncoimmunology 2014; 3:in press
-
(2014)
Oncoimmunology
, vol.3
-
-
Galluzzi, L.1
Kroemer, G.2
Eggermont, A.3
-
5
-
-
84883219603
-
Trial watch: monoclonal antibodies in cancer therapy
-
23482847
-
E.Vacchelli, A.Eggermont, J.Galon, C.Sautes-Fridman, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: monoclonal antibodies in cancer therapy. Oncoimmunology 2013; 2:e22789; PMID:23482847; dx.doi.org/10.4161/onci.22789
-
(2013)
Oncoimmunology
, vol.2
, pp. 22789
-
-
Vacchelli, E.1
Eggermont, A.2
Galon, J.3
Sautes-Fridman, C.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
6
-
-
84899115962
-
Trial watch: tumor-targeting monoclonal antibodies in cancer therapy
-
24605265
-
E.Vacchelli, F.Aranda, A.Eggermont, J.Galon, C.Sautes-Fridman, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: tumor-targeting monoclonal antibodies in cancer therapy. Oncoimmunology 2014; 3:e27048; PMID:24605265; dx.doi.org/10.4161/onci.27048
-
(2014)
Oncoimmunology
, vol.3
, pp. 27048
-
-
Vacchelli, E.1
Aranda, F.2
Eggermont, A.3
Galon, J.4
Sautes-Fridman, C.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
7
-
-
38949178132
-
Dose and schedule study of panitumumab monotherapy in patients with advanced solid malignancies
-
18223225
-
L.M.Weiner, A.S.Belldegrun, J.Crawford, A.W.Tolcher, P.Lockbaum, R.H.Arends, L.Navale, R.G.Amado, G.Schwab, R.A.Figlin. Dose and schedule study of panitumumab monotherapy in patients with advanced solid malignancies. Clin Cancer Res 2008; 14:502-8; PMID:18223225; dx.doi.org/10.1158/1078-0432.CCR-07-1509
-
(2008)
Clin Cancer Res
, vol.14
, pp. 502-508
-
-
Weiner, L.M.1
Belldegrun, A.S.2
Crawford, J.3
Tolcher, A.W.4
Lockbaum, P.5
Arends, R.H.6
Navale, L.7
Amado, R.G.8
Schwab, G.9
Figlin, R.A.10
-
8
-
-
84886944943
-
TLR3 agonists improve the immunostimulatory potential of cetuximab against EGFR head and neck cancer cells
-
23894722
-
C.Ming Lim, R.Stephenson, A.M.Salazar, R.L.Ferris. TLR3 agonists improve the immunostimulatory potential of cetuximab against EGFR head and neck cancer cells. Oncoimmunology 2013; 2:e24677; PMID:23894722; dx.doi.org/10.4161/onci.24677
-
(2013)
Oncoimmunology
, vol.2
, pp. 24677
-
-
Ming Lim, C.1
Stephenson, R.2
Salazar, A.M.3
Ferris, R.L.4
-
9
-
-
77952912435
-
Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types
-
20150762
-
P.J.Kaplan-Lefko, J.D.Graves, S.J.Zoog, Y.Pan, J.Wall, D.G.Branstetter, J.Moriguchi, A.Coxon, J.N.Huard, R.Xu Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types. Cancer Biol Ther 2010; 9:618-31; PMID:20150762; dx.doi.org/10.4161/cbt.9.8.11264
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 618-631
-
-
Kaplan-Lefko, P.J.1
Graves, J.D.2
Zoog, S.J.3
Pan, Y.4
Wall, J.5
Branstetter, D.G.6
Moriguchi, J.7
Coxon, A.8
Huard, J.N.9
Xu, R.10
-
10
-
-
30444461383
-
Fcgamma receptors: old friends and new family members
-
16413920
-
F.Nimmerjahn, J.V.Ravetch. Fcgamma receptors: old friends and new family members. Immunity 2006; 24:19-28; PMID:16413920; dx.doi.org/10.1016/j.immuni.2005.11.010
-
(2006)
Immunity
, vol.24
, pp. 19-28
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
11
-
-
84885366553
-
Antibody-dependent cell cytotoxicity in monoclonal antibody-mediated tumor immunotherapy
-
22720225
-
P.Hubert, S.Amigorena. Antibody-dependent cell cytotoxicity in monoclonal antibody-mediated tumor immunotherapy. Oncoimmunology 2012; 1:103-5; PMID:22720225; dx.doi.org/10.4161/onci.1.1.17963
-
(2012)
Oncoimmunology
, vol.1
, pp. 103-105
-
-
Hubert, P.1
Amigorena, S.2
-
12
-
-
84886944363
-
Boosting antibody-dependant cellular cytotoxicity against tumor cells with a CD137 stimulatory antibody
-
23162770
-
R.Houot, H.Kohrt, R.Levy. Boosting antibody-dependant cellular cytotoxicity against tumor cells with a CD137 stimulatory antibody. Oncoimmunology 2012; 1:957-8; PMID:23162770; dx.doi.org/10.4161/onci.19974
-
(2012)
Oncoimmunology
, vol.1
, pp. 957-958
-
-
Houot, R.1
Kohrt, H.2
Levy, R.3
-
13
-
-
84877135653
-
Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells
-
23162748
-
T.Kute, J.R.StehleJr, D.Ornelles, N.Walker, O.Delbono, J.P.Vaughn. Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells. Oncoimmunology 2012; 1:810-21; PMID:23162748; dx.doi.org/10.4161/onci.20447
-
(2012)
Oncoimmunology
, vol.1
, pp. 810-821
-
-
Kute, T.1
Stehle, J.R.2
Ornelles, D.3
Walker, N.4
Delbono, O.5
Vaughn, J.P.6
-
14
-
-
79955011744
-
Molecular mechanisms of the antitumor effects of anti-CD20 antibodies
-
21196171
-
M.Winiarska, E.Glodkowska-Mrowka, J.Bil, J.Golab. Molecular mechanisms of the antitumor effects of anti-CD20 antibodies. Front Biosci 2011; 16:277-306; PMID:21196171; dx.doi.org/10.2741/3688
-
(2011)
Front Biosci
, vol.16
, pp. 277-306
-
-
Winiarska, M.1
Glodkowska-Mrowka, E.2
Bil, J.3
Golab, J.4
-
15
-
-
73849090193
-
Complement and its role in innate and adaptive immune responses
-
20010915
-
J.R.Dunkelberger, W.C.Song. Complement and its role in innate and adaptive immune responses. Cell Res 2010; 20:34-50; PMID:20010915; dx.doi.org/10.1038/cr.2009.139
-
(2010)
Cell Res
, vol.20
, pp. 34-50
-
-
Dunkelberger, J.R.1
Song, W.C.2
-
16
-
-
70349437186
-
Complement regulators and inhibitory proteins
-
19730437
-
P.F.Zipfel, C.Skerka. Complement regulators and inhibitory proteins. Nat Rev Immunol 2009; 9:729-40; PMID:19730437; dx.doi.org/10.1038/nri2620
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 729-740
-
-
Zipfel, P.F.1
Skerka, C.2
-
17
-
-
83655196673
-
Novel monoclonal antibodies for cancer treatment: the trifunctional antibody catumaxomab (removab)
-
21716847
-
D.Seimetz. Novel monoclonal antibodies for cancer treatment: the trifunctional antibody catumaxomab (removab). J Cancer 2011; 2:309-16; PMID:21716847; dx.doi.org/10.7150/jca.2.309
-
(2011)
J Cancer
, vol.2
, pp. 309-316
-
-
Seimetz, D.1
-
18
-
-
84886945370
-
Targeting EpCAM (CD326) for immunotherapy in hepatoblastoma
-
23482411
-
S.Armeanu-Ebinger, A.Hoh, J.Wenz, J.Fuchs. Targeting EpCAM (CD326) for immunotherapy in hepatoblastoma. Oncoimmunology 2013; 2:e22620; PMID:23482411; dx.doi.org/10.4161/onci.22620
-
(2013)
Oncoimmunology
, vol.2
, pp. 22620
-
-
Armeanu-Ebinger, S.1
Hoh, A.2
Wenz, J.3
Fuchs, J.4
-
19
-
-
0037093241
-
Randomized controlled trial of yttrium-90-labeled ibritumomab tiuxetan radioimmunotherapy versus rituximab immunotherapy for patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin's lymphoma
-
12011122
-
T.E.Witzig, L.I.Gordon, F.Cabanillas, M.S.Czuczman, C.Emmanouilides, R.Joyce, B.L.Pohlman, N.L.Bartlett, G.A.Wiseman, N.Padre Randomized controlled trial of yttrium-90-labeled ibritumomab tiuxetan radioimmunotherapy versus rituximab immunotherapy for patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin's lymphoma. J Clin Oncol 2002; 20:2453-63; PMID:12011122; dx.doi.org/10.1200/JCO.2002.11.076
-
(2002)
J Clin Oncol
, vol.20
, pp. 2453-2463
-
-
Witzig, T.E.1
Gordon, L.I.2
Cabanillas, F.3
Czuczman, M.S.4
Emmanouilides, C.5
Joyce, R.6
Pohlman, B.L.7
Bartlett, N.L.8
Wiseman, G.A.9
Padre, N.10
-
20
-
-
0034662510
-
Radioimmunotherapy with iodine (131)I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience
-
10942366
-
M.S.Kaminski, J.Estes, K.R.Zasadny, I.R.Francis, C.W.Ross, M.Tuck, D.Regan, S.Fisher, J.Gutierrez, S.Kroll Radioimmunotherapy with iodine (131)I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience. Blood 2000; 96:1259-66; PMID:10942366
-
(2000)
Blood
, vol.96
, pp. 1259-1266
-
-
Kaminski, M.S.1
Estes, J.2
Zasadny, K.R.3
Francis, I.R.4
Ross, C.W.5
Tuck, M.6
Regan, D.7
Fisher, S.8
Gutierrez, J.9
Kroll, S.10
-
21
-
-
77956337746
-
Antibody-drug conjugates for cancer: poised to deliver?
-
20811367
-
B.Hughes. Antibody-drug conjugates for cancer: poised to deliver? Nat Rev Drug Discov 2010; 9:665-7; PMID:20811367; dx.doi.org/10.1038/nrd3270
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 665-667
-
-
Hughes, B.1
-
22
-
-
84906043250
-
Antibody-drug conjugates: an emerging modality for the treatment of cancer
-
25123209
-
M.Leal, P.Sapra, S.A.Hurvitz, P.Senter, A.Wahl, M.Schutten, D.K.Shah, N.Haddish-Berhane, O.Kabbarah. Antibody-drug conjugates: an emerging modality for the treatment of cancer. Ann N Y Acad Sci 2014; 1321:41-54; PMID:25123209; dx.doi.org/10.1111/nyas.12499
-
(2014)
Ann N Y Acad Sci
, vol.1321
, pp. 41-54
-
-
Leal, M.1
Sapra, P.2
Hurvitz, S.A.3
Senter, P.4
Wahl, A.5
Schutten, M.6
Shah, D.K.7
Haddish-Berhane, N.8
Kabbarah, O.9
-
23
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
15136787
-
N.Ferrara, K.J.Hillan, H.P.Gerber, W.Novotny. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004; 3:391-400; PMID:15136787; dx.doi.org/10.1038/nrd1381
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
Novotny, W.4
-
24
-
-
84876872556
-
Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment
-
23243624
-
A.J.Michielsen, E.J.Ryan, J.N.O'Sullivan. Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment. Oncoimmunology 2012; 1:1445-7; PMID:23243624; dx.doi.org/10.4161/onci.21318
-
(2012)
Oncoimmunology
, vol.1
, pp. 1445-1447
-
-
Michielsen, A.J.1
Ryan, E.J.2
O'Sullivan, J.N.3
-
25
-
-
34447136111
-
A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib
-
17616683
-
T.de La Motte Rouge, L.Galluzzi, K.A.Olaussen, Y.Zermati, E.Tasdemir, T.Robert, H.Ripoche, V.Lazar, P.Dessen, F.Harper A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. Cancer Res 2007; 67:6253-62; PMID:17616683; dx.doi.org/10.1158/0008-5472.CAN-07-0538
-
(2007)
Cancer Res
, vol.67
, pp. 6253-6262
-
-
de La Motte Rouge, T.1
Galluzzi, L.2
Olaussen, K.A.3
Zermati, Y.4
Tasdemir, E.5
Robert, T.6
Ripoche, H.7
Lazar, V.8
Dessen, P.9
Harper, F.10
-
26
-
-
18744390084
-
Cetuximab
-
15962524
-
R.M.Goldberg. Cetuximab. Nat Rev Drug Discov 2005; Suppl:S10-11; Available: http://www.ncbi.nlm.nih.gov/pubmed/?term=Goldberg+RM.+Cetuximab.+Nat+Rev+Drug+Discov+2005%3B+Suppl%3AS10-1; PMID:15962524; dx.doi.org/10.1038/nrd1728
-
(2005)
Nat Rev Drug Discov
, pp. 10-11
-
-
Goldberg, R.M.1
-
27
-
-
33846564399
-
Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma
-
17096332
-
Y.Kawaguchi, K.Kono, K.Mimura, H.Sugai, H.Akaike, H.Fujii. Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma. Int J Cancer 2007; 120:781-7; PMID:17096332; dx.doi.org/10.1002/ijc.22370
-
(2007)
Int J Cancer
, vol.120
, pp. 781-787
-
-
Kawaguchi, Y.1
Kono, K.2
Mimura, K.3
Sugai, H.4
Akaike, H.5
Fujii, H.6
-
28
-
-
84877096819
-
Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients
-
23444227
-
R.M.Srivastava, S.C.Lee, P.A.Andrade Filho, C.A.Lord, H.B.Jie, H.C.Davidson, A.López-Albaitero, S.P.Gibson, W.E.Gooding, S.Ferrone Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients. Clin Cancer Res 2013; 19:1858-72; PMID:23444227; dx.doi.org/10.1158/1078-0432.CCR-12-2426
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1858-1872
-
-
Srivastava, R.M.1
Lee, S.C.2
Andrade Filho, P.A.3
Lord, C.A.4
Jie, H.B.5
Davidson, H.C.6
López-Albaitero, A.7
Gibson, S.P.8
Gooding, W.E.9
Ferrone, S.10
-
29
-
-
84886945205
-
EGFR expression levels affect the mode of action of EGFR-targeting monoclonal antibodies
-
23762793
-
S.Derer, S.Lohse, T.Valerius. EGFR expression levels affect the mode of action of EGFR-targeting monoclonal antibodies. Oncoimmunology 2013; 2:e24052; PMID:23762793; dx.doi.org/10.4161/onci.24052
-
(2013)
Oncoimmunology
, vol.2
, pp. 24052
-
-
Derer, S.1
Lohse, S.2
Valerius, T.3
-
30
-
-
84896712625
-
Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody
-
24475376
-
B.D.Choi, P.C.Gedeon, L.Sanchez-Perez, D.D.Bigner, J.H.Sampson. Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody. Oncoimmunology 2013; 2:e26757; PMID:24475376; dx.doi.org/10.4161/onci.26757
-
(2013)
Oncoimmunology
, vol.2
, pp. 26757
-
-
Choi, B.D.1
Gedeon, P.C.2
Sanchez-Perez, L.3
Bigner, D.D.4
Sampson, J.H.5
-
31
-
-
84881552775
-
A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system
-
23734318
-
B.D.Choi, I.Pastan, D.D.Bigner, J.H.Sampson. A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system. Oncoimmunology 2013; 2:e23639; PMID:23734318; dx.doi.org/10.4161/onci.23639
-
(2013)
Oncoimmunology
, vol.2
, pp. 23639
-
-
Choi, B.D.1
Pastan, I.2
Bigner, D.D.3
Sampson, J.H.4
-
32
-
-
84867858547
-
Blinatumomab: a historical perspective
-
22940266
-
D.Nagorsen, P.Kufer, P.A.Baeuerle, R.Bargou. Blinatumomab: a historical perspective. Pharmacol Ther 2012; 136:334-42; PMID:22940266; dx.doi.org/10.1016/j.pharmthera.2012.07.013
-
(2012)
Pharmacol Ther
, vol.136
, pp. 334-342
-
-
Nagorsen, D.1
Kufer, P.2
Baeuerle, P.A.3
Bargou, R.4
-
33
-
-
79955662260
-
Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab
-
21419116
-
D.Nagorsen, P.A.Baeuerle. Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab. Exp Cell Res 2011; 317:1255-60; PMID:21419116; dx.doi.org/10.1016/j.yexcr.2011.03.010
-
(2011)
Exp Cell Res
, vol.317
, pp. 1255-1260
-
-
Nagorsen, D.1
Baeuerle, P.A.2
-
34
-
-
79959312575
-
Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
-
21576633
-
M.S.Topp, P.Kufer, N.Gokbuget, M.Goebeler, M.Klinger, S.Neumann, H.A.Horst, T.Raff, A.Viardot, M.Schmid Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol 2011; 29:2493-8; PMID:21576633; dx.doi.org/10.1200/JCO.2010.32.7270
-
(2011)
J Clin Oncol
, vol.29
, pp. 2493-2498
-
-
Topp, M.S.1
Kufer, P.2
Gokbuget, N.3
Goebeler, M.4
Klinger, M.5
Neumann, S.6
Horst, H.A.7
Raff, T.8
Viardot, A.9
Schmid, M.10
-
35
-
-
84871491706
-
Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL
-
23024237
-
M.S.Topp, N.Gokbuget, G.Zugmaier, E.Degenhard, M.E.Goebeler, M.Klinger, S.A.Neumann, H.A.Horst, T.Raff, A.Viardot Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL. Blood 2012; 120:5185-7; PMID:23024237; dx.doi.org/10.1182/blood-2012-07-441030
-
(2012)
Blood
, vol.120
, pp. 5185-5187
-
-
Topp, M.S.1
Gokbuget, N.2
Zugmaier, G.3
Degenhard, E.4
Goebeler, M.E.5
Klinger, M.6
Neumann, S.A.7
Horst, H.A.8
Raff, T.9
Viardot, A.10
-
36
-
-
84900844248
-
Biting back: BiTE antibodies as a promising therapy for acute myeloid leukemia
-
24617311
-
R.B.Walter. Biting back: BiTE antibodies as a promising therapy for acute myeloid leukemia. Expert Rev Hematol 2014; 7:317-9; PMID:24617311; dx.doi.org/10.1586/17474086.2014.896190
-
(2014)
Expert Rev Hematol
, vol.7
, pp. 317-319
-
-
Walter, R.B.1
-
37
-
-
77957995258
-
A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer
-
20808314
-
J.F.Rossi, S.Negrier, N.D.James, I.Kocak, R.Hawkins, H.Davis, U.Prabhakar, X.Qin, P.Mulders, B.Berns. A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer. Br J Cancer 2010; 103:1154-62; PMID:20808314; dx.doi.org/10.1038/sj.bjc.6605872
-
(2010)
Br J Cancer
, vol.103
, pp. 1154-1162
-
-
Rossi, J.F.1
Negrier, S.2
James, N.D.3
Kocak, I.4
Hawkins, R.5
Davis, H.6
Prabhakar, U.7
Qin, X.8
Mulders, P.9
Berns, B.10
-
38
-
-
79951556761
-
Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma
-
21241278
-
S.A.Hunsucker, V.Magarotto, D.J.Kuhn, S.M.Kornblau, M.Wang, D.M.Weber, S.K.Thomas, J.J.Shah, P.M.Voorhees, H.Xie Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma. Br J Haematol 2011; 152:579-92; PMID:21241278; dx.doi.org/10.1111/j.1365-2141.2010.08533.x
-
(2011)
Br J Haematol
, vol.152
, pp. 579-592
-
-
Hunsucker, S.A.1
Magarotto, V.2
Kuhn, D.J.3
Kornblau, S.M.4
Wang, M.5
Weber, D.M.6
Thomas, S.K.7
Shah, J.J.8
Voorhees, P.M.9
Xie, H.10
-
39
-
-
84907056599
-
Siltuximab for multicentric Castleman disease
-
25110138
-
Y.C.Liu, K.Stone, F.van Rhee. Siltuximab for multicentric Castleman disease. Expert Rev Hematol 2014; 7:545-57; PMID:25110138; dx.doi.org/10.1586/17474086.2014.946402
-
(2014)
Expert Rev Hematol
, vol.7
, pp. 545-557
-
-
Liu, Y.C.1
Stone, K.2
van Rhee, F.3
-
40
-
-
84879849025
-
A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease
-
23659971
-
R.Kurzrock, P.M.Voorhees, C.Casper, R.R.Furman, L.Fayad, S.Lonial, H.Borghaei, S.Jagannath, L.Sokol, S.Z.Usmani A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease. Clin Cancer Res 2013; 19:3659-70; PMID:23659971; dx.doi.org/10.1158/1078-0432.CCR-12-3349
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3659-3670
-
-
Kurzrock, R.1
Voorhees, P.M.2
Casper, C.3
Furman, R.R.4
Fayad, L.5
Lonial, S.6
Borghaei, H.7
Jagannath, S.8
Sokol, L.9
Usmani, S.Z.10
-
41
-
-
77957283115
-
Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease
-
20625121
-
F.van Rhee, L.Fayad, P.Voorhees, R.Furman, S.Lonial, H.Borghaei, L.Sokol, J.Crawford, M.Cornfeld, M.Qi Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease. J Clin Oncol 2010; 28:3701-8; PMID:20625121; dx.doi.org/10.1200/JCO.2009.27.2377
-
(2010)
J Clin Oncol
, vol.28
, pp. 3701-3708
-
-
van Rhee, F.1
Fayad, L.2
Voorhees, P.3
Furman, R.4
Lonial, S.5
Borghaei, H.6
Sokol, L.7
Crawford, J.8
Cornfeld, M.9
Qi, M.10
-
42
-
-
84905005470
-
Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial
-
25042199
-
F.van Rhee, R.S.Wong, N.Munshi, J.F.Rossi, X.Y.Ke, A.Fossa, D.Simpson, M.Capra, T.Liu, R.K.Hsieh Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial. Lancet Oncol 2014; 15:966-74; PMID:25042199; dx.doi.org/10.1016/S1470-2045(14)70319-5
-
(2014)
Lancet Oncol
, vol.15
, pp. 966-974
-
-
van Rhee, F.1
Wong, R.S.2
Munshi, N.3
Rossi, J.F.4
Ke, X.Y.5
Fossa, A.6
Simpson, D.7
Capra, M.8
Liu, T.9
Hsieh, R.K.10
-
43
-
-
67650674112
-
Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer
-
19513949
-
Y.Krupitskaya, H.A.Wakelee. Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer. Curr Opin Investig Drugs 2009; 10:597-605; PMID:19513949
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 597-605
-
-
Krupitskaya, Y.1
Wakelee, H.A.2
-
44
-
-
84891041748
-
Gastrointestinal cancer: targeted therapies in gastric cancer-the dawn of a new era
-
24300880
-
M.A.Shah. Gastrointestinal cancer: targeted therapies in gastric cancer-the dawn of a new era. Nat Rev Clin Oncol 2014; 11:10-11; PMID:24300880; dx.doi.org/10.1038/nrclinonc.2013.231
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 10-11
-
-
Shah, M.A.1
-
45
-
-
84892852372
-
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
-
24094768
-
C.S.Fuchs, J.Tomasek, C.J.Yong, F.Dumitru, R.Passalacqua, C.Goswami, H.Safran, L.V.dos Santos, G.Aprile, D.R.Ferry Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet 2014; 383:31-9; PMID:24094768; dx.doi.org/10.1016/S0140-6736(13)61719-5
-
(2014)
Lancet
, vol.383
, pp. 31-39
-
-
Fuchs, C.S.1
Tomasek, J.2
Yong, C.J.3
Dumitru, F.4
Passalacqua, R.5
Goswami, C.6
Safran, H.7
dos Santos, L.V.8
Aprile, G.9
Ferry, D.R.10
-
46
-
-
84908139963
-
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial
-
25240821
-
H.Wilke, K.Muro, E.Van Cutsem, S.C.Oh, G.Bodoky, Y.Shimada, S.Hironaka, N.Sugimoto, O.Lipatov, T.Y.Kim Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial. Lancet Oncol 2014; 15:1224-35; PMID:25240821; dx.doi.org/10.1016/S1470-2045(14)70420-6
-
(2014)
Lancet Oncol
, vol.15
, pp. 1224-1235
-
-
Wilke, H.1
Muro, K.2
Van Cutsem, E.3
Oh, S.C.4
Bodoky, G.5
Shimada, Y.6
Hironaka, S.7
Sugimoto, N.8
Lipatov, O.9
Kim, T.Y.10
-
47
-
-
84857349967
-
Obinutuzumab for the treatment of lymphoproliferative disorders
-
22283718
-
C.Owen, D.A.Stewart. Obinutuzumab for the treatment of lymphoproliferative disorders. Expert Opin Biol Ther 2012; 12:343-51; PMID:22283718; dx.doi.org/10.1517/14712598.2012.657622
-
(2012)
Expert Opin Biol Ther
, vol.12
, pp. 343-351
-
-
Owen, C.1
Stewart, D.A.2
-
48
-
-
79953183947
-
Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab
-
21296976
-
L.Bologna, E.Gotti, M.Manganini, A.Rambaldi, T.Intermesoli, M.Introna, J.Golay. Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab. J Immunol 2011; 186:3762-9; PMID:21296976; dx.doi.org/10.4049/jimmunol.1000303
-
(2011)
J Immunol
, vol.186
, pp. 3762-3769
-
-
Bologna, L.1
Gotti, E.2
Manganini, M.3
Rambaldi, A.4
Intermesoli, T.5
Introna, M.6
Golay, J.7
-
49
-
-
67650657179
-
GA-101, a third-generation, humanized and glyco-engineered anti-CD20 mAb for the treatment of B-cell lymphoid malignancies
-
19513948
-
T.Robak. GA-101, a third-generation, humanized and glyco-engineered anti-CD20 mAb for the treatment of B-cell lymphoid malignancies. Curr Opin Investig Drugs 2009; 10:588-96; PMID:19513948
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 588-596
-
-
Robak, T.1
-
50
-
-
84905506991
-
U.S. Food and drug administration approval: obinutuzumab in combination with chlorambucil for the treatment of previously untreated chronic lymphocytic leukemia
-
24824310
-
H.Z.Lee, B.W.Miller, V.E.Kwitkowski, S.Ricci, P.DelValle, H.Saber, J.Grillo, J.Bullock, J.Florian, N.Mehrotra U.S. Food and drug administration approval: obinutuzumab in combination with chlorambucil for the treatment of previously untreated chronic lymphocytic leukemia. Clin Cancer Res 2014; 20:3902-7; PMID:24824310; dx.doi.org/10.1158/1078-0432.CCR-14-0516
-
(2014)
Clin Cancer Res
, vol.20
, pp. 3902-3907
-
-
Lee, H.Z.1
Miller, B.W.2
Kwitkowski, V.E.3
Ricci, S.4
DelValle, P.5
Saber, H.6
Grillo, J.7
Bullock, J.8
Florian, J.9
Mehrotra, N.10
-
51
-
-
84896453785
-
Movement toward optimization of CLL therapy
-
24645950
-
K.R.Rai, J.C.Barrientos. Movement toward optimization of CLL therapy. N Engl J Med 2014; 370:1160-2; PMID:24645950; dx.doi.org/10.1056/NEJMe1400599
-
(2014)
N Engl J Med
, vol.370
, pp. 1160-1162
-
-
Rai, K.R.1
Barrientos, J.C.2
-
52
-
-
84894552888
-
Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions
-
24401022
-
V.Goede, K.Fischer, R.Busch, A.Engelke, B.Eichhorst, C.M.Wendtner, T.Chagorova, J.de la Serna, M.S.Dilhuydy, T.Illmer Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions. N Engl J Med 2014; 370:1101-10; PMID:24401022; dx.doi.org/10.1056/NEJMoa1313984
-
(2014)
N Engl J Med
, vol.370
, pp. 1101-1110
-
-
Goede, V.1
Fischer, K.2
Busch, R.3
Engelke, A.4
Eichhorst, B.5
Wendtner, C.M.6
Chagorova, T.7
de la Serna, J.8
Dilhuydy, M.S.9
Illmer, T.10
-
53
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
15175435
-
H.Hurwitz, L.Fehrenbacher, W.Novotny, T.Cartwright, J.Hainsworth, W.Heim, J.Berlin, A.Baron, S.Griffing, E.Holmgren Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-42; PMID:15175435; dx.doi.org/10.1056/NEJMoa032691
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
-
54
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
17167137
-
A.Sandler, R.Gray, M.C.Perry, J.Brahmer, J.H.Schiller, A.Dowlati, R.Lilenbaum, D.H.Johnson. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355:2542-50; PMID:17167137; dx.doi.org/10.1056/NEJMoa061884
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
55
-
-
84886943665
-
The immunomodulatory effects of bevacizumab on systemic immunity in patients with metastatic melanoma
-
23762809
-
A.S.Mansfield, W.K.Nevala, E.A.Lieser, A.A.Leontovich, S.N.Markovic. The immunomodulatory effects of bevacizumab on systemic immunity in patients with metastatic melanoma. Oncoimmunology 2013; 2:e24436; PMID:23762809; dx.doi.org/10.4161/onci.24436
-
(2013)
Oncoimmunology
, vol.2
, pp. 24436
-
-
Mansfield, A.S.1
Nevala, W.K.2
Lieser, E.A.3
Leontovich, A.A.4
Markovic, S.N.5
-
56
-
-
48549095021
-
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone
-
18593931
-
J.Hoffmann, I.Vitale, B.Buchmann, L.Galluzzi, W.Schwede, L.Senovilla, W.Skuballa, S.Vivet, R.B.Lichtner, J.M.Vicencio Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone. Cancer Res 2008; 68:5301-8; PMID:18593931; dx.doi.org/10.1158/0008-5472.CAN-08-0237
-
(2008)
Cancer Res
, vol.68
, pp. 5301-5308
-
-
Hoffmann, J.1
Vitale, I.2
Buchmann, B.3
Galluzzi, L.4
Schwede, W.5
Senovilla, L.6
Skuballa, W.7
Vivet, S.8
Lichtner, R.B.9
Vicencio, J.M.10
-
57
-
-
84880732251
-
An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells
-
23482968
-
L.Senovilla, I.Vitale, I.Martins, O.Kepp, L.Galluzzi, L.Zitvogel, M.Castedo, G.Kroemer. An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells. Oncoimmunology 2013; 2:e22409; PMID:23482968; dx.doi.org/10.4161/onci.22409
-
(2013)
Oncoimmunology
, vol.2
, pp. 22409
-
-
Senovilla, L.1
Vitale, I.2
Martins, I.3
Kepp, O.4
Galluzzi, L.5
Zitvogel, L.6
Castedo, M.7
Kroemer, G.8
-
58
-
-
79960957085
-
Mitotic catastrophe: a mechanism for avoiding genomic instability
-
21527953
-
I.Vitale, L.Galluzzi, M.Castedo, G.Kroemer. Mitotic catastrophe: a mechanism for avoiding genomic instability. Nat Rev Mol Cell Biol 2011; 12:385-92; PMID:21527953; dx.doi.org/10.1038/nrm3115
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 385-392
-
-
Vitale, I.1
Galluzzi, L.2
Castedo, M.3
Kroemer, G.4
-
59
-
-
84894207820
-
Improved survival with bevacizumab in advanced cervical cancer
-
24552320
-
K.S.Tewari, M.W.Sill, H.J.Long3rd, R.T.Penson, H.Huang, L.M.Ramondetta, L.M.Landrum, A.Oaknin, T.J.Reid, M.M.Leitao Improved survival with bevacizumab in advanced cervical cancer. N Engl J Med 2014; 370:734-43; PMID:24552320; dx.doi.org/10.1056/NEJMoa1309748
-
(2014)
N Engl J Med
, vol.370
, pp. 734-743
-
-
Tewari, K.S.1
Sill, M.W.2
Long, H.J.3
Penson, R.T.4
Huang, H.5
Ramondetta, L.M.6
Landrum, L.M.7
Oaknin, A.8
Reid, T.J.9
Leitao, M.M.10
-
60
-
-
77950502126
-
Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia
-
20194866
-
W.G.Wierda, T.J.Kipps, J.Mayer, S.Stilgenbauer, C.D.Williams, A.Hellmann, T.Robak, R.R.Furman, P.Hillmen, M.Trneny Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia. J Clin Oncol 2010; 28:1749-55; PMID:20194866; dx.doi.org/10.1200/JCO.2009.25.3187
-
(2010)
J Clin Oncol
, vol.28
, pp. 1749-1755
-
-
Wierda, W.G.1
Kipps, T.J.2
Mayer, J.3
Stilgenbauer, S.4
Williams, C.D.5
Hellmann, A.6
Robak, T.7
Furman, R.R.8
Hillmen, P.9
Trneny, M.10
-
62
-
-
77956250271
-
U.S. food and drug administration approval: ofatumumab for the treatment of patients with chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab
-
20601446
-
S.J.Lemery, J.Zhang, M.D.Rothmann, J.Yang, J.Earp, H.Zhao, A.McDougal, A.Pilaro, R.Chiang, J.E.Gootenberg U.S. food and drug administration approval: ofatumumab for the treatment of patients with chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab. Clin Cancer Res 2010; 16:433-18; PMID:20601446; dx.doi.org/10.1158/1078-0432.CCR-10-0570
-
(2010)
Clin Cancer Res
, vol.16
, pp. 418-433
-
-
Lemery, S.J.1
Zhang, J.2
Rothmann, M.D.3
Yang, J.4
Earp, J.5
Zhao, H.6
McDougal, A.7
Pilaro, A.8
Chiang, R.9
Gootenberg, J.E.10
-
63
-
-
84902582355
-
Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity
-
24404423
-
L.Boissel, M.Betancur-Boissel, W.Lu, D.S.Krause, R.A.Van Etten, W.S.Wels, H.Klingemann. Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity. Oncoimmunology 2013; 2:e26527; PMID:24404423; dx.doi.org/10.4161/onci.26527
-
(2013)
Oncoimmunology
, vol.2
, pp. 26527
-
-
Boissel, L.1
Betancur-Boissel, M.2
Lu, W.3
Krause, D.S.4
Van Etten, R.A.5
Wels, W.S.6
Klingemann, H.7
-
64
-
-
84904266704
-
Changes in the treatment landscape for chronic lymphoid leukemia
-
25014693
-
R.Foa. Changes in the treatment landscape for chronic lymphoid leukemia. N Engl J Med 2014; 371:273-4; PMID:25014693; dx.doi.org/10.1056/NEJMe1405766
-
(2014)
N Engl J Med
, vol.371
, pp. 273-274
-
-
Foa, R.1
-
65
-
-
84896480883
-
Ofatumumab + chlorambucil versus chlorambucil alone in patients with untreated chronic lymphocytic leukemia (CLL): results of the phase III study complement 1 (OMB110911)
-
P.Hillmen, T.Robak, A.Janssens, K.Govindbabu, S.Grosicki, J.Mayer Ofatumumab + chlorambucil versus chlorambucil alone in patients with untreated chronic lymphocytic leukemia (CLL): results of the phase III study complement 1 (OMB110911). ASH Meeting Abstr 2013:528; Available: https://ash.confex.com/ash/2013/webprogram/Paper58498.html
-
(2013)
ASH Meeting Abstr
, pp. 528
-
-
Hillmen, P.1
Robak, T.2
Janssens, A.3
Govindbabu, K.4
Grosicki, S.5
Mayer, J.6
-
66
-
-
84883233976
-
Trial watch: cardiac glycosides and cancer therapy
-
23525565
-
L.Menger, E.Vacchelli, O.Kepp, A.Eggermont, E.Tartour, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: cardiac glycosides and cancer therapy. Oncoimmunology 2013; 2:e23082; PMID:23525565; dx.doi.org/10.4161/onci.23082
-
(2013)
Oncoimmunology
, vol.2
, pp. 23082
-
-
Menger, L.1
Vacchelli, E.2
Kepp, O.3
Eggermont, A.4
Tartour, E.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
67
-
-
84885432340
-
Trial watch: DNA vaccines for cancer therapy
-
23734328
-
L.Senovilla, E.Vacchelli, P.Garcia, A.Eggermont, W.H.Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: DNA vaccines for cancer therapy. Oncoimmunology 2013; 2:e23803; PMID:23734328; dx.doi.org/10.4161/onci.23803
-
(2013)
Oncoimmunology
, vol.2
, pp. 23803
-
-
Senovilla, L.1
Vacchelli, E.2
Garcia, P.3
Eggermont, A.4
Fridman, W.H.5
Galon, J.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
68
-
-
84885162273
-
Trial watch: adoptive cell transfer for anticancer immunotherapy
-
23762803
-
E.Vacchelli, A.Eggermont, W.H.Fridman, J.Galon, E.Tartour, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: adoptive cell transfer for anticancer immunotherapy. Oncoimmunology 2013; 2:e24238; PMID:23762803; dx.doi.org/10.4161/onci.24238
-
(2013)
Oncoimmunology
, vol.2
, pp. 24238
-
-
Vacchelli, E.1
Eggermont, A.2
Fridman, W.H.3
Galon, J.4
Tartour, E.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
69
-
-
75649113373
-
PD-1 expression in T-cell lymphomas and reactive lymphoid entities: potential overlap in staining patterns between lymphoma and viral lymphadenitis
-
20087161
-
C.Krishnan, R.A.Warnke, D.A.Arber, Y.Natkunam. PD-1 expression in T-cell lymphomas and reactive lymphoid entities: potential overlap in staining patterns between lymphoma and viral lymphadenitis. Am J Surg Pathol 2010; 34:178-89; PMID:20087161; dx.doi.org/10.1097/PAS.0b013e3181cc7e79
-
(2010)
Am J Surg Pathol
, vol.34
, pp. 178-189
-
-
Krishnan, C.1
Warnke, R.A.2
Arber, D.A.3
Natkunam, Y.4
-
70
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
20525992
-
F.S.Hodi, S.J.O'Day, D.F.McDermott, R.W.Weber, J.A.Sosman, J.B.Haanen, R.Gonzalez, C.Robert, D.Schadendorf, J.C.Hassel Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363:711-23; PMID:20525992; dx.doi.org/10.1056/NEJMoa1003466
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
71
-
-
75249083669
-
Immunity unleashed in melanoma
-
20152761
-
M.K.Erdmann. Immunity unleashed in melanoma. Lancet Oncol 2010; 11:108-9; PMID:20152761; dx.doi.org/10.1016/S1470-2045(09)70400-0
-
(2010)
Lancet Oncol
, vol.11
, pp. 108-109
-
-
Erdmann, M.K.1
-
72
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study
-
20004617
-
J.D.Wolchok, B.Neyns, G.Linette, S.Negrier, J.Lutzky, L.Thomas, W.Waterfield, D.Schadendorf, M.Smylie, T.GuthrieJr Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol 2010; 11:155-64; PMID:20004617; dx.doi.org/10.1016/S1470-2045(09)70334-1
-
(2010)
Lancet Oncol
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
Negrier, S.4
Lutzky, J.5
Thomas, L.6
Waterfield, W.7
Schadendorf, D.8
Smylie, M.9
Guthrie, T.10
-
73
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
25034862
-
C.Robert, A.Ribas, J.D.Wolchok, F.S.Hodi, O.Hamid, R.Kefford, J.S.Weber, A.M.Joshua, W.J.Hwu, T.C.Gangadhar Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 2014; 384:1109-17; PMID:25034862; dx.doi.org/10.1016/S0140-6736(14)60958-2
-
(2014)
Lancet
, vol.384
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
Hodi, F.S.4
Hamid, O.5
Kefford, R.6
Weber, J.S.7
Joshua, A.M.8
Hwu, W.J.9
Gangadhar, T.C.10
-
74
-
-
84907543029
-
Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL)
-
A.Ribas, F.S.Hodi, R.Kefford, O.Hamid, A.Daud, J.D.Wolchok Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL). ASCO Meeting Abstr 2014; 32:LBA9000; Available: http://meetinglibrary.asco.org/content/133842-144
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 9000
-
-
Ribas, A.1
Hodi, F.S.2
Kefford, R.3
Hamid, O.4
Daud, A.5
Wolchok, J.D.6
-
75
-
-
84902449791
-
Combined OX40 ligation plus CTLA-4 blockade: more than the sum of its parts
-
25050194
-
S.N.Linch, W.L.Redmond. Combined OX40 ligation plus CTLA-4 blockade: more than the sum of its parts. Oncoimmunology 2014; 3:e28245; PMID:25050194; dx.doi.org/10.4161/onci.28245
-
(2014)
Oncoimmunology
, vol.3
, pp. 28245
-
-
Linch, S.N.1
Redmond, W.L.2
-
76
-
-
84899128381
-
Immune checkpoint blockade in malignant mesothelioma: a novel therapeutic strategy against a deadly disease?
-
24734215
-
L.Calabro, M.Maio. Immune checkpoint blockade in malignant mesothelioma: a novel therapeutic strategy against a deadly disease? Oncoimmunology 2014; 3:e27482; PMID:24734215; dx.doi.org/10.4161/onci.27482
-
(2014)
Oncoimmunology
, vol.3
, pp. 27482
-
-
Calabro, L.1
Maio, M.2
-
77
-
-
84906510279
-
Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes
-
25083336
-
L.Robert, C.Harview, R.Emerson, X.Wang, S.Mok, B.Homet, B.Comin-Anduix, R.C.Koya, H.Robins, P.C.Tumeh Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes. Oncoimmunology 2014; 3:e29244; PMID:25083336; dx.doi.org/10.4161/onci.29244
-
(2014)
Oncoimmunology
, vol.3
, pp. 29244
-
-
Robert, L.1
Harview, C.2
Emerson, R.3
Wang, X.4
Mok, S.5
Homet, B.6
Comin-Anduix, B.7
Koya, R.C.8
Robins, H.9
Tumeh, P.C.10
-
78
-
-
0031957306
-
Rituximab: a new therapeutic monoclonal antibody for non-Hodgkin's lymphoma
-
9652253
-
S.D.Scott. Rituximab: a new therapeutic monoclonal antibody for non-Hodgkin's lymphoma. Cancer Pract 1998; 6:195-7; PMID:9652253; dx.doi.org/10.1046/j.1523-5394.1998.006003195.x
-
(1998)
Cancer Pract
, vol.6
, pp. 195-197
-
-
Scott, S.D.1
-
79
-
-
84887403617
-
Haematological cancer: rituximab maintenance improves the outcome of elderly patients with FL
-
23999211
-
B.Jones. Haematological cancer: rituximab maintenance improves the outcome of elderly patients with FL. Nat Rev Clin Oncol 2013; 10:607; PMID:23999211; dx.doi.org/10.1038/nrclinonc.2013.164
-
(2013)
Nat Rev Clin Oncol
, vol.10
, pp. 607
-
-
Jones, B.1
-
80
-
-
79955556128
-
Castleman's disease: from basic mechanisms to molecular therapeutics
-
21441298
-
H.E.El-Osta, R.Kurzrock. Castleman's disease: from basic mechanisms to molecular therapeutics. Oncologist 2011; 16:497-511; PMID:21441298; dx.doi.org/10.1634/theoncologist.2010-0212
-
(2011)
Oncologist
, vol.16
, pp. 497-511
-
-
El-Osta, H.E.1
Kurzrock, R.2
-
81
-
-
84906903314
-
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial
-
24933332
-
E.B.Garon, T.E.Ciuleanu, O.Arrieta, K.Prabhash, K.N.Syrigos, T.Goksel, K.Park, V.Gorbunova, R.D.Kowalyszyn, J.Pikiel Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial. Lancet 2014; 384:665-73; PMID:24933332; dx.doi.org/10.1016/S0140-6736(14)60845-X
-
(2014)
Lancet
, vol.384
, pp. 665-673
-
-
Garon, E.B.1
Ciuleanu, T.E.2
Arrieta, O.3
Prabhash, K.4
Syrigos, K.N.5
Goksel, T.6
Park, K.7
Gorbunova, V.8
Kowalyszyn, R.D.9
Pikiel, J.10
-
82
-
-
84879748062
-
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
-
23782158
-
J.C.Byrd, R.R.Furman, S.E.Coutre, I.W.Flinn, J.A.Burger, K.A.Blum, B.Grant, J.P.Sharman, M.Coleman, W.G.Wierda Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med 2013; 369:32-42; PMID:23782158; dx.doi.org/10.1056/NEJMoa1215637
-
(2013)
N Engl J Med
, vol.369
, pp. 32-42
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.E.3
Flinn, I.W.4
Burger, J.A.5
Blum, K.A.6
Grant, B.7
Sharman, J.P.8
Coleman, M.9
Wierda, W.G.10
-
83
-
-
84881225049
-
Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma
-
23782157
-
M.L.Wang, S.Rule, P.Martin, A.Goy, R.Auer, B.S.Kahl, W.Jurczak, R.H.Advani, J.E.Romaguera, M.E.Williams Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma. N Engl J Med 2013; 369:507-16; PMID:23782157; dx.doi.org/10.1056/NEJMoa1306220
-
(2013)
N Engl J Med
, vol.369
, pp. 507-516
-
-
Wang, M.L.1
Rule, S.2
Martin, P.3
Goy, A.4
Auer, R.5
Kahl, B.S.6
Jurczak, W.7
Advani, R.H.8
Romaguera, J.E.9
Williams, M.E.10
-
84
-
-
84904252369
-
Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia
-
24881631
-
J.C.Byrd, J.R.Brown, S.O'Brien, J.C.Barrientos, N.E.Kay, N.M.Reddy, S.Coutre, C.S.Tam, S.P.Mulligan, U.Jaeger Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia. N Engl J Med 2014; 371:213-23; PMID:24881631; dx.doi.org/10.1056/NEJMoa1400376
-
(2014)
N Engl J Med
, vol.371
, pp. 213-223
-
-
Byrd, J.C.1
Brown, J.R.2
O'Brien, S.3
Barrientos, J.C.4
Kay, N.E.5
Reddy, N.M.6
Coutre, S.7
Tam, C.S.8
Mulligan, S.P.9
Jaeger, U.10
-
85
-
-
84888129994
-
Docetaxel or pemetrexed with or without cetuximab in recurrent or progressive non-small-cell lung cancer after platinum-based therapy: a phase 3, open-label, randomised trial
-
24231627
-
E.S.Kim, M.Neubauer, A.Cohn, L.Schwartzberg, L.Garbo, J.Caton, F.Robert, C.Reynolds, T.Katz, S.Chittoor Docetaxel or pemetrexed with or without cetuximab in recurrent or progressive non-small-cell lung cancer after platinum-based therapy: a phase 3, open-label, randomised trial. Lancet Oncol 2013; 14:1326-36; PMID:24231627; dx.doi.org/10.1016/S1470-2045(13)70473-X
-
(2013)
Lancet Oncol
, vol.14
, pp. 1326-1336
-
-
Kim, E.S.1
Neubauer, M.2
Cohn, A.3
Schwartzberg, L.4
Garbo, L.5
Caton, J.6
Robert, F.7
Reynolds, C.8
Katz, T.9
Chittoor, S.10
-
86
-
-
84899837376
-
Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: the AURELIA open-label randomized phase III trial
-
24637997
-
E.Pujade-Lauraine, F.Hilpert, B.Weber, A.Reuss, A.Poveda, G.Kristensen, R.Sorio, I.Vergote, P.Witteveen, A.Bamias Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: the AURELIA open-label randomized phase III trial. J Clin Oncol 2014; 32:1302-8; PMID:24637997; dx.doi.org/10.1200/JCO.2013.51.4489
-
(2014)
J Clin Oncol
, vol.32
, pp. 1302-1308
-
-
Pujade-Lauraine, E.1
Hilpert, F.2
Weber, B.3
Reuss, A.4
Poveda, A.5
Kristensen, G.6
Sorio, R.7
Vergote, I.8
Witteveen, P.9
Bamias, A.10
-
87
-
-
84908126746
-
Bevacizumab plus chemotherapy versus chemotherapy alone as second-line treatment for patients with HER2-negative locally recurrent or metastatic breast cancer after first-line treatment with bevacizumab plus chemotherapy (TANIA): an open-label, randomised phase 3 trial
-
25273342
-
G.von Minckwitz, F.Puglisi, J.Cortes, E.Vrdoljak, N.Marschner, C.Zielinski, C.Villanueva, G.Romieu, I.Lang, E.Ciruelos Bevacizumab plus chemotherapy versus chemotherapy alone as second-line treatment for patients with HER2-negative locally recurrent or metastatic breast cancer after first-line treatment with bevacizumab plus chemotherapy (TANIA): an open-label, randomised phase 3 trial. Lancet Oncol 2014; 15:1269-78; PMID:25273342; dx.doi.org/10.1016/S1470-2045(14)70439-5
-
(2014)
Lancet Oncol
, vol.15
, pp. 1269-1278
-
-
von Minckwitz, G.1
Puglisi, F.2
Cortes, J.3
Vrdoljak, E.4
Marschner, N.5
Zielinski, C.6
Villanueva, C.7
Romieu, G.8
Lang, I.9
Ciruelos, E.10
-
88
-
-
84901587677
-
Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial
-
24794243
-
G.von Minckwitz, A.Schneeweiss, S.Loibl, C.Salat, C.Denkert, M.Rezai, J.U.Blohmer, C.Jackisch, S.Paepke, B.Gerber Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial. Lancet Oncol 2014; 15:747-56; PMID:24794243; dx.doi.org/10.1016/S1470-2045(14)70160-3
-
(2014)
Lancet Oncol
, vol.15
, pp. 747-756
-
-
von Minckwitz, G.1
Schneeweiss, A.2
Loibl, S.3
Salat, C.4
Denkert, C.5
Rezai, M.6
Blohmer, J.U.7
Jackisch, C.8
Paepke, S.9
Gerber, B.10
-
89
-
-
84902962349
-
Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma
-
24711551
-
F.Navid, P.M.Sondel, R.Barfield, B.L.Shulkin, R.A.Kaufman, J.A.Allay, J.Gan, P.Hutson, S.Seo, K.Kim Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma. J Clin Oncol 2014; 32:1445-52; PMID:24711551; dx.doi.org/10.1200/JCO.2013.50.4423
-
(2014)
J Clin Oncol
, vol.32
, pp. 1445-1452
-
-
Navid, F.1
Sondel, P.M.2
Barfield, R.3
Shulkin, B.L.4
Kaufman, R.A.5
Allay, J.A.6
Gan, J.7
Hutson, P.8
Seo, S.9
Kim, K.10
-
90
-
-
84886423341
-
Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index
-
24132639
-
L.R.Desnoyers, O.Vasiljeva, J.H.Richardson, A.Yang, E.E.Menendez, T.W.Liang, C.Wong, P.H.Bessette, K.Kamath, S.J.Moore Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index. Sci Transl Med 2013; 5:207ra144; PMID:24132639; dx.doi.org/10.1126/scitranslmed.3006682
-
(2013)
Sci Transl Med
, vol.5
, pp. 144
-
-
Desnoyers, L.R.1
Vasiljeva, O.2
Richardson, J.H.3
Yang, A.4
Menendez, E.E.5
Liang, T.W.6
Wong, C.7
Bessette, P.H.8
Kamath, K.9
Moore, S.J.10
-
91
-
-
84896265113
-
Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates
-
24572574
-
B.Q.Spring, A.O.Abu-Yousif, A.Palanisami, I.Rizvi, X.Zheng, Z.Mai, S.Anbil, R.B.Sears, L.B.Mensah, R.Goldschmidt Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates. Proc Natl Acad Sci U S A 2014; 111:E933-42; PMID:24572574; dx.doi.org/10.1073/pnas.1319493111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 933-942
-
-
Spring, B.Q.1
Abu-Yousif, A.O.2
Palanisami, A.3
Rizvi, I.4
Zheng, X.5
Mai, Z.6
Anbil, S.7
Sears, R.B.8
Mensah, L.B.9
Goldschmidt, R.10
-
92
-
-
84899096210
-
Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies
-
24711415
-
O.M.Pearce, H.Laubli, A.Verhagen, P.Secrest, J.Zhang, N.M.Varki, P.R.Crocker, J.D.Bui, A.Varki. Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies. Proc Natl Acad Sci U S A 2014; 111:5998-6003; PMID:24711415; dx.doi.org/10.1073/pnas.1209067111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 5998-6003
-
-
Pearce, O.M.1
Laubli, H.2
Verhagen, A.3
Secrest, P.4
Zhang, J.5
Varki, N.M.6
Crocker, P.R.7
Bui, J.D.8
Varki, A.9
-
93
-
-
84893821285
-
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy
-
24430180
-
N.Gul, L.Babes, K.Siegmund, R.Korthouwer, M.Bogels, R.Braster, G.Vidarsson, T.L.ten Hagen, P.Kubes, M.van Egmond. Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. J Clin Invest 2014; 124:812-23; PMID:24430180; dx.doi.org/10.1172/JCI66776
-
(2014)
J Clin Invest
, vol.124
, pp. 812-823
-
-
Gul, N.1
Babes, L.2
Siegmund, K.3
Korthouwer, R.4
Bogels, M.5
Braster, R.6
Vidarsson, G.7
ten Hagen, T.L.8
Kubes, P.9
van Egmond, M.10
-
94
-
-
84890087376
-
The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging
-
24177426
-
F.Montalvao, Z.Garcia, S.Celli, B.Breart, J.Deguine, N.Van Rooijen, P.Bousso. The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging. J Clin Invest 2013; 123:5098-103; PMID:24177426; dx.doi.org/10.1172/JCI70972
-
(2013)
J Clin Invest
, vol.123
, pp. 5098-5103
-
-
Montalvao, F.1
Garcia, Z.2
Celli, S.3
Breart, B.4
Deguine, J.5
Van Rooijen, N.6
Bousso, P.7
-
95
-
-
84887198387
-
Bispecific antibody to ErbB2 overcomes trastuzumab resistance through comprehensive blockade of ErbB2 heterodimerization
-
24046294
-
B.Li, Y.Meng, L.Zheng, X.Zhang, Q.Tong, W.Tan, S.Hu, H.Li, Y.Chen, J.Song Bispecific antibody to ErbB2 overcomes trastuzumab resistance through comprehensive blockade of ErbB2 heterodimerization. Cancer Res 2013; 73:6471-83; PMID:24046294; dx.doi.org/10.1158/0008-5472.CAN-13-0657
-
(2013)
Cancer Res
, vol.73
, pp. 6471-6483
-
-
Li, B.1
Meng, Y.2
Zheng, L.3
Zhang, X.4
Tong, Q.5
Tan, W.6
Hu, S.7
Li, H.8
Chen, Y.9
Song, J.10
-
96
-
-
84890291467
-
Extending the chimeric receptor-based T-cell targeting strategy to solid tumors
-
24244901
-
C.Rossig. Extending the chimeric receptor-based T-cell targeting strategy to solid tumors. Oncoimmunology 2013; 2:e26091; PMID:24244901; dx.doi.org/10.4161/onci.26091
-
(2013)
Oncoimmunology
, vol.2
, pp. 26091
-
-
Rossig, C.1
-
97
-
-
84892772608
-
T lymphocytes expressing a CD16 signaling receptor exert antibody-dependent cancer cell killing
-
24197131
-
K.Kudo, C.Imai, P.Lorenzini, T.Kamiya, K.Kono, A.M.Davidoff, W.J.Chng, D.Campana. T lymphocytes expressing a CD16 signaling receptor exert antibody-dependent cancer cell killing. Cancer Res 2014; 74:93-103; PMID:24197131; dx.doi.org/10.1158/0008-5472.CAN-13-1365
-
(2014)
Cancer Res
, vol.74
, pp. 93-103
-
-
Kudo, K.1
Imai, C.2
Lorenzini, P.3
Kamiya, T.4
Kono, K.5
Davidoff, A.M.6
Chng, W.J.7
Campana, D.8
-
98
-
-
84902137525
-
Targeting CD137 enhances the efficacy of cetuximab
-
24837434
-
H.E.Kohrt, A.D.Colevas, R.Houot, K.Weiskopf, M.J.Goldstein, P.Lund, A.Mueller, I.Sagiv-Barfi, A.Marabelle, R.Lira Targeting CD137 enhances the efficacy of cetuximab. J Clin Invest 2014; 124:2668-82; PMID:24837434; dx.doi.org/10.1172/JCI73014
-
(2014)
J Clin Invest
, vol.124
, pp. 2668-2682
-
-
Kohrt, H.E.1
Colevas, A.D.2
Houot, R.3
Weiskopf, K.4
Goldstein, M.J.5
Lund, P.6
Mueller, A.7
Sagiv-Barfi, I.8
Marabelle, A.9
Lira, R.10
-
99
-
-
84894030202
-
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
-
24326534
-
H.E.Kohrt, A.Thielens, A.Marabelle, I.Sagiv-Barfi, C.Sola, F.Chanuc, N.Fuseri, C.Bonnafous, D.Czerwinski, A.Rajapaksa Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies. Blood 2014; 123:678-86; PMID:24326534; dx.doi.org/10.1182/blood-2013-08-519199
-
(2014)
Blood
, vol.123
, pp. 678-686
-
-
Kohrt, H.E.1
Thielens, A.2
Marabelle, A.3
Sagiv-Barfi, I.4
Sola, C.5
Chanuc, F.6
Fuseri, N.7
Bonnafous, C.8
Czerwinski, D.9
Rajapaksa, A.10
-
101
-
-
84892409564
-
Tumor-derived lactate and myeloid-derived suppressor cells: linking metabolism to cancer immunology
-
24404426
-
Z.Husain, P.Seth, V.P.Sukhatme. Tumor-derived lactate and myeloid-derived suppressor cells: linking metabolism to cancer immunology. Oncoimmunology 2013; 2:e26383; PMID:24404426; dx.doi.org/10.4161/onci.26383
-
(2013)
Oncoimmunology
, vol.2
, pp. 26383
-
-
Husain, Z.1
Seth, P.2
Sukhatme, V.P.3
-
102
-
-
84887132805
-
Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII
-
24030978
-
G.Gondi, J.Mysliwietz, A.Hulikova, J.P.Jen, P.Swietach, E.Kremmer, R.Zeidler. Antitumor efficacy of a monoclonal antibody that inhibits the activity of cancer-associated carbonic anhydrase XII. Cancer Res 2013; 73:6494-503; PMID:24030978; dx.doi.org/10.1158/0008-5472.CAN-13-1110
-
(2013)
Cancer Res
, vol.73
, pp. 6494-6503
-
-
Gondi, G.1
Mysliwietz, J.2
Hulikova, A.3
Jen, J.P.4
Swietach, P.5
Kremmer, E.6
Zeidler, R.7
-
103
-
-
84885024224
-
An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin
-
23928993
-
A.P.Garner, C.U.Bialucha, E.R.Sprague, J.T.Garrett, Q.Sheng, S.Li, O.Sineshchekova, P.Saxena, C.R.Sutton, D.Chen An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin. Cancer Res 2013; 73:6024-35; PMID:23928993; dx.doi.org/10.1158/0008-5472.CAN-13-1198
-
(2013)
Cancer Res
, vol.73
, pp. 6024-6035
-
-
Garner, A.P.1
Bialucha, C.U.2
Sprague, E.R.3
Garrett, J.T.4
Sheng, Q.5
Li, S.6
Sineshchekova, O.7
Saxena, P.8
Sutton, C.R.9
Chen, D.10
-
104
-
-
84885049277
-
Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110alpha inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers
-
23918797
-
J.T.Garrett, C.R.Sutton, R.Kurupi, C.U.Bialucha, S.A.Ettenberg, S.D.Collins, Q.Sheng, J.Wallweber, L.Defazio-Eli, C.L.Arteaga. Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110alpha inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers. Cancer Res 2013; 73:6013-23; PMID:23918797; dx.doi.org/10.1158/0008-5472.CAN-13-1191
-
(2013)
Cancer Res
, vol.73
, pp. 6013-6023
-
-
Garrett, J.T.1
Sutton, C.R.2
Kurupi, R.3
Bialucha, C.U.4
Ettenberg, S.A.5
Collins, S.D.6
Sheng, Q.7
Wallweber, J.8
Defazio-Eli, L.9
Arteaga, C.L.10
-
105
-
-
84897133359
-
Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer
-
24667376
-
J.J.Tao, P.Castel, N.Radosevic-Robin, M.Elkabets, N.Auricchio, N.Aceto, G.Weitsman, P.Barber, B.Vojnovic, H.Ellis Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer. Sci Signal 2014; 7:ra29; PMID:24667376; dx.doi.org/10.1126/scisignal.2005125
-
(2014)
Sci Signal
, vol.7
, pp. 29
-
-
Tao, J.J.1
Castel, P.2
Radosevic-Robin, N.3
Elkabets, M.4
Auricchio, N.5
Aceto, N.6
Weitsman, G.7
Barber, P.8
Vojnovic, B.9
Ellis, H.10
-
106
-
-
84894254971
-
An antibody-drug conjugate that targets tissue factor exhibits potent therapeutic activity against a broad range of solid tumors
-
24371232
-
E.C.Breij, B.E.de Goeij, S.Verploegen, D.H.Schuurhuis, A.Amirkhosravi, J.Francis, V.B.Miller, M.Houtkamp, W.K.Bleeker, D.Satijn An antibody-drug conjugate that targets tissue factor exhibits potent therapeutic activity against a broad range of solid tumors. Cancer Res 2014; 74:1214-26; PMID:24371232; dx.doi.org/10.1158/0008-5472.CAN-13-2440
-
(2014)
Cancer Res
, vol.74
, pp. 1214-1226
-
-
Breij, E.C.1
de Goeij, B.E.2
Verploegen, S.3
Schuurhuis, D.H.4
Amirkhosravi, A.5
Francis, J.6
Miller, V.B.7
Houtkamp, M.8
Bleeker, W.K.9
Satijn, D.10
-
107
-
-
84905734365
-
Apo2L/TRAIL and the death receptor 5 agonist antibody AMG 655 cooperate to promote receptor clustering and antitumor activity
-
25043603
-
J.D.Graves, J.J.Kordich, T.H.Huang, J.Piasecki, T.L.Bush, T.Sullivan, I.N.Foltz, W.Chang, H.Douangpanya, T.Dang Apo2L/TRAIL and the death receptor 5 agonist antibody AMG 655 cooperate to promote receptor clustering and antitumor activity. Cancer Cell 2014; 26:177-89; PMID:25043603; dx.doi.org/10.1016/j.ccr.2014.04.028
-
(2014)
Cancer Cell
, vol.26
, pp. 177-189
-
-
Graves, J.D.1
Kordich, J.J.2
Huang, T.H.3
Piasecki, J.4
Bush, T.L.5
Sullivan, T.6
Foltz, I.N.7
Chang, W.8
Douangpanya, H.9
Dang, T.10
-
108
-
-
84884990167
-
Combination of two anti-CD5 monoclonal antibodies synergistically induces complement-dependent cytotoxicity of chronic lymphocytic leukaemia cells
-
23927424
-
J.L.Klitgaard, K.Koefoed, C.Geisler, O.V.Gadeberg, D.A.Frank, J.Petersen, M.W.Pedersen. Combination of two anti-CD5 monoclonal antibodies synergistically induces complement-dependent cytotoxicity of chronic lymphocytic leukaemia cells. Br J Haematol 2013; 163:182-93; PMID:23927424
-
(2013)
Br J Haematol
, vol.163
, pp. 182-193
-
-
Klitgaard, J.L.1
Koefoed, K.2
Geisler, C.3
Gadeberg, O.V.4
Frank, D.A.5
Petersen, J.6
Pedersen, M.W.7
-
109
-
-
84907494587
-
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
-
25228655
-
T.T.Junttila, J.Li, J.Johnston, M.Hristopoulos, R.Clark, D.Ellerman, B.E.Wang, Y.Li, M.Mathieu, G.Li Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells. Cancer Res 2014; 74:5561-71; PMID:25228655; dx.doi.org/10.1158/0008-5472.CAN-13-3622-T
-
(2014)
Cancer Res
, vol.74
, pp. 5561-5571
-
-
Junttila, T.T.1
Li, J.2
Johnston, J.3
Hristopoulos, M.4
Clark, R.5
Ellerman, D.6
Wang, B.E.7
Li, Y.8
Mathieu, M.9
Li, G.10
-
110
-
-
84872921660
-
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
-
23177514
-
A.Grothey, E.Van Cutsem, A.Sobrero, S.Siena, A.Falcone, M.Ychou, Y.Humblet, O.Bouché, L.Mineur, C.Barone Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 2013; 381:303-12; PMID:23177514; dx.doi.org/10.1016/S0140-6736(12)61900-X
-
(2013)
Lancet
, vol.381
, pp. 303-312
-
-
Grothey, A.1
Van Cutsem, E.2
Sobrero, A.3
Siena, S.4
Falcone, A.5
Ychou, M.6
Humblet, Y.7
Bouché, O.8
Mineur, L.9
Barone, C.10
-
111
-
-
84866888498
-
Regorafenib for patients with previously untreated metastatic or unresectable renal-cell carcinoma: a single-group phase 2 trial
-
22959186
-
T.Eisen, H.Joensuu, P.D.Nathan, P.G.Harper, M.Z.Wojtukiewicz, S.Nicholson, A.Bahl, P.Tomczak, S.Pyrhonen, K.Fife Regorafenib for patients with previously untreated metastatic or unresectable renal-cell carcinoma: a single-group phase 2 trial. Lancet Oncol 2012; 13:1055-62; PMID:22959186; dx.doi.org/10.1016/S1470-2045(12)70364-9
-
(2012)
Lancet Oncol
, vol.13
, pp. 1055-1062
-
-
Eisen, T.1
Joensuu, H.2
Nathan, P.D.3
Harper, P.G.4
Wojtukiewicz, M.Z.5
Nicholson, S.6
Bahl, A.7
Tomczak, P.8
Pyrhonen, S.9
Fife, K.10
-
112
-
-
84862785051
-
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial
-
22452896
-
V.A.Miller, V.Hirsh, J.Cadranel, Y.M.Chen, K.Park, S.W.Kim, C.Zhou, W.C.Su, M.Wang, Y.Sun Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol 2012; 13:528-38; PMID:22452896; dx.doi.org/10.1016/S1470-2045(12)70087-6
-
(2012)
Lancet Oncol
, vol.13
, pp. 528-538
-
-
Miller, V.A.1
Hirsh, V.2
Cadranel, J.3
Chen, Y.M.4
Park, K.5
Kim, S.W.6
Zhou, C.7
Su, W.C.8
Wang, M.9
Sun, Y.10
-
113
-
-
84862819699
-
Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): a phase 2 trial
-
22452895
-
J.C.Yang, J.Y.Shih, W.C.Su, T.C.Hsia, C.M.Tsai, S.H.Ou, C.J.Yu, G.C.Chang, C.L.Ho, L.V.Sequist Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): a phase 2 trial. Lancet Oncol 2012; 13:539-48; PMID:22452895; dx.doi.org/10.1016/S1470-2045(12)70086-4
-
(2012)
Lancet Oncol
, vol.13
, pp. 539-548
-
-
Yang, J.C.1
Shih, J.Y.2
Su, W.C.3
Hsia, T.C.4
Tsai, C.M.5
Ou, S.H.6
Yu, C.J.7
Chang, G.C.8
Ho, C.L.9
Sequist, L.V.10
-
114
-
-
84919434353
-
Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy
-
24917416
-
J.Lu, L.Lee-Gabel, M.C.Nadeau, T.M.Ferencz, S.A.Soefje. Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy. J Oncol Pharm Pract 2014; Available: http://www.ncbi.nlm.nih.gov/pubmed/?term=Clinical+evaluation+of+compounds+targeting+PD-1%2FPD-L1+pathway+for+cancer+immunotherapy; PMID:24917416
-
(2014)
J Oncol Pharm Pract
-
-
Lu, J.1
Lee-Gabel, L.2
Nadeau, M.C.3
Ferencz, T.M.4
Soefje, S.A.5
-
115
-
-
84911161740
-
Emerging immunotherapies in the treatment of non-small cell lung cancer (NSCLC): the role of immune checkpoint inhibitors
-
24685885
-
C.J.Langer. Emerging immunotherapies in the treatment of non-small cell lung cancer (NSCLC): the role of immune checkpoint inhibitors. Am J Clin Oncol 2014; Available: http://www.ncbi.nlm.nih.gov/pubmed/?term=Emerging+Immunotherapies+in+the+Treatment+of+Non-Small+Cell+Lung+Cancer+(NSCLC)%3A+The+Role+of+Immune+Checkpoint+Inhibitors; PMID:24685885
-
(2014)
Am J Clin Oncol
-
-
Langer, C.J.1
-
116
-
-
84890933630
-
Update on immune checkpoint inhibitors in lung cancer
-
24357746
-
B.C.Creelan. Update on immune checkpoint inhibitors in lung cancer. Cancer Control 2014; 21:80-9; PMID:24357746
-
(2014)
Cancer Control
, vol.21
, pp. 80-89
-
-
Creelan, B.C.1
-
117
-
-
84919701827
-
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
-
25301704
-
S.Peirs, F.Matthijssens, S.Goossens, I.Van de Walle, K.Ruggero, C.E.de Bock, S.Degryse, K.Canté-Barrett, D.Briot, E.Clappier ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia. Blood 2014; 124(25):3738-47; PMID:25301704; dx.doi.org/10.1182/blood-2014-05-574566
-
(2014)
Blood
-
-
Peirs, S.1
Matthijssens, F.2
Goossens, S.3
Van de Walle, I.4
Ruggero, K.5
de Bock, C.E.6
Degryse, S.7
Canté-Barrett, K.8
Briot, D.9
Clappier, E.10
-
118
-
-
84906908155
-
ABT-199 Shows Effectiveness in CLL
-
ABT-199 Shows Effectiveness in CLL. Cancer Discov 2014; 4:OF7; dx.doi.org/10.1158/2159-8290.CD-NB2014-102
-
(2014)
Cancer Discov
, vol.4
, pp. 7
-
-
-
119
-
-
84904439445
-
Targeting BCL2 for the treatment of lymphoid malignancies
-
25048785
-
M.A.Anderson, D.Huang, A.Roberts. Targeting BCL2 for the treatment of lymphoid malignancies. Semin Hematol 2014; 51:219-27; PMID:25048785; dx.doi.org/10.1053/j.seminhematol.2014.05.008
-
(2014)
Semin Hematol
, vol.51
, pp. 219-227
-
-
Anderson, M.A.1
Huang, D.2
Roberts, A.3
-
120
-
-
84886719568
-
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial
-
24120480
-
B.Nordlinger, H.Sorbye, B.Glimelius, G.J.Poston, P.M.Schlag, P.Rougier, W.O.Bechstein, J.N.Primrose, E.T.Walpole, M.Finch-Jones Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial. Lancet Oncol 2013; 14:1208-15; PMID:24120480; dx.doi.org/10.1016/S1470-2045(13)70447-9
-
(2013)
Lancet Oncol
, vol.14
, pp. 1208-1215
-
-
Nordlinger, B.1
Sorbye, H.2
Glimelius, B.3
Poston, G.J.4
Schlag, P.M.5
Rougier, P.6
Bechstein, W.O.7
Primrose, J.N.8
Walpole, E.T.9
Finch-Jones, M.10
-
121
-
-
84925604287
-
The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation
-
25122067
-
V.Yadav, T.F.Burke, L.Huber, R.D.Van Horn, Y.Zhang, S.G.Buchanan, E.M.Chan, J.J.Starling, R.P.Beckmann, S.B.Peng. The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation. Mol Cancer Ther 2014; 13:2253-63; PMID:25122067; dx.doi.org/10.1158/1535-7163.MCT-14-0257
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 2253-2263
-
-
Yadav, V.1
Burke, T.F.2
Huber, L.3
Van Horn, R.D.4
Zhang, Y.5
Buchanan, S.G.6
Chan, E.M.7
Starling, J.J.8
Beckmann, R.P.9
Peng, S.B.10
-
122
-
-
84930696140
-
Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine
-
24919854
-
L.M.Gelbert, S.Cai, X.Lin, C.Sanchez-Martinez, M.Del Prado, M.J.Lallena, M.J.Lallena, R.Torres, R.T.Ajamie, G.N.Wishart Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine. Invest New Drugs 2014; 32:825-37; PMID:24919854; dx.doi.org/10.1007/s10637-014-0120-7
-
(2014)
Invest New Drugs
, vol.32
, pp. 825-837
-
-
Gelbert, L.M.1
Cai, S.2
Lin, X.3
Sanchez-Martinez, C.4
Del Prado, M.5
Lallena, M.J.6
Lallena, M.J.7
Torres, R.8
Ajamie, R.T.9
Wishart, G.N.10
-
123
-
-
0036941305
-
Monoclonal antibody therapy with CAMPATH-1H in patients with relapsed high- and low-grade non-Hodgkin's lymphomas: a multicenter phase I/II study
-
11807632
-
M.Uppenkamp, A.Engert, V.Diehl, D.Bunjes, D.Huhn, G.Brittinger. Monoclonal antibody therapy with CAMPATH-1H in patients with relapsed high- and low-grade non-Hodgkin's lymphomas: a multicenter phase I/II study. Ann Hematol 2002; 81:26-32; PMID:11807632; dx.doi.org/10.1007/s00277-001-0394-7
-
(2002)
Ann Hematol
, vol.81
, pp. 26-32
-
-
Uppenkamp, M.1
Engert, A.2
Diehl, V.3
Bunjes, D.4
Huhn, D.5
Brittinger, G.6
-
124
-
-
0036044579
-
Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia
-
12141952
-
B.Schmitt, C.M.Wendtner, M.Bergmann, R.Busch, A.Franke, R.Pasold, R.Schlag, G.Hopfinger, W.Hiddemann, B.Emmerich Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia. Clin Lymphoma 2002; 3:26-35; PMID:12141952; dx.doi.org/10.3816/CLM.2002.n.008
-
(2002)
Clin Lymphoma
, vol.3
, pp. 26-35
-
-
Schmitt, B.1
Wendtner, C.M.2
Bergmann, M.3
Busch, R.4
Franke, A.5
Pasold, R.6
Schlag, R.7
Hopfinger, G.8
Hiddemann, W.9
Emmerich, B.10
-
126
-
-
84863688504
-
The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
-
22781692
-
P.D.Senter, E.L.Sievers. The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma. Nat Biotechnol 2012; 30:631-7; PMID:22781692; dx.doi.org/10.1038/nbt.2289
-
(2012)
Nat Biotechnol
, vol.30
, pp. 631-637
-
-
Senter, P.D.1
Sievers, E.L.2
-
127
-
-
84884204298
-
Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia
-
23085751
-
E.Lainey, A.Wolfromm, N.Marie, D.Enot, M.Scoazec, C.Bouteloup, C.Leroy, J.B.Micol, S.De Botton, L.Galluzzi Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia. Oncogene 2013; 32:4331-42; PMID:23085751; dx.doi.org/10.1038/onc.2012.469
-
(2013)
Oncogene
, vol.32
, pp. 4331-4342
-
-
Lainey, E.1
Wolfromm, A.2
Marie, N.3
Enot, D.4
Scoazec, M.5
Bouteloup, C.6
Leroy, C.7
Micol, J.B.8
De Botton, S.9
Galluzzi, L.10
-
128
-
-
79960456078
-
Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia
-
21654193
-
S.Thepot, E.Lainey, T.Cluzeau, M.Sebert, C.Leroy, L.Ades, M.Tailler, L.Galluzzi, F.Baran-Marszak, H.Roudot Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia. Cell Cycle 2011; 10:2323-30; PMID:21654193; dx.doi.org/10.4161/cc.10.14.16399
-
(2011)
Cell Cycle
, vol.10
, pp. 2323-2330
-
-
Thepot, S.1
Lainey, E.2
Cluzeau, T.3
Sebert, M.4
Leroy, C.5
Ades, L.6
Tailler, M.7
Galluzzi, L.8
Baran-Marszak, F.9
Roudot, H.10
-
129
-
-
84886944438
-
Expression patterns of chemokine receptors on circulating T cells from myelodysplastic syndrome patients
-
23525654
-
K.E.Sand, K.P.Rye, B.Mannsaker, O.Bruserud, A.O.Kittang. Expression patterns of chemokine receptors on circulating T cells from myelodysplastic syndrome patients. Oncoimmunology 2013; 2:e23138; PMID:23525654; dx.doi.org/10.4161/onci.23138
-
(2013)
Oncoimmunology
, vol.2
, pp. 23138
-
-
Sand, K.E.1
Rye, K.P.2
Mannsaker, B.3
Bruserud, O.4
Kittang, A.O.5
-
130
-
-
84892409579
-
Trial watch: lenalidomide-based immunochemotherapy
-
24482747
-
M.Semeraro, E.Vacchelli, A.Eggermont, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: lenalidomide-based immunochemotherapy. Oncoimmunology 2013; 2:e26494; PMID:24482747; dx.doi.org/10.4161/onci.26494
-
(2013)
Oncoimmunology
, vol.2
, pp. 26494
-
-
Semeraro, M.1
Vacchelli, E.2
Eggermont, A.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
131
-
-
84899051541
-
Novel insights into the mechanism of action of lenalidomide
-
25340011
-
M.Semeraro, L.Galluzzi. Novel insights into the mechanism of action of lenalidomide. Oncoimmunology 2014; 3:e28386; PMID:25340011; dx.doi.org/10.4161/onci.28386
-
(2014)
Oncoimmunology
, vol.3
, pp. 28386
-
-
Semeraro, M.1
Galluzzi, L.2
-
132
-
-
40949091368
-
U.S. Food and Drug Administration approval: panitumumab for epidermal growth factor receptor-expressing metastatic colorectal carcinoma with progression following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens
-
18316547
-
R.M.Giusti, K.Shastri, A.M.Pilaro, C.Fuchs, R.Cordoba-Rodriguez, K.Koti, M.Rothmann, A.Y.Men, H.Zhao, M.Hughes U.S. Food and Drug Administration approval: panitumumab for epidermal growth factor receptor-expressing metastatic colorectal carcinoma with progression following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens. Clin Cancer Res 2008; 14:1296-302; PMID:18316547; dx.doi.org/10.1158/1078-0432.CCR-07-1354
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1296-1302
-
-
Giusti, R.M.1
Shastri, K.2
Pilaro, A.M.3
Fuchs, C.4
Cordoba-Rodriguez, R.5
Koti, K.6
Rothmann, M.7
Men, A.Y.8
Zhao, H.9
Hughes, M.10
-
133
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
19114685
-
J.R.Hecht, E.Mitchell, T.Chidiac, C.Scroggin, C.Hagenstad, D.Spigel, J.Marshall, A.Cohn, D.McCollum, P.Stella A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol 2009; 27:672-80; PMID:19114685; dx.doi.org/10.1200/JCO.2008.19.8135
-
(2009)
J Clin Oncol
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
Scroggin, C.4
Hagenstad, C.5
Spigel, D.6
Marshall, J.7
Cohn, A.8
McCollum, D.9
Stella, P.10
-
134
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
18316791
-
R.G.Amado, M.Wolf, M.Peeters, E.Van Cutsem, S.Siena, D.J.Freeman, T.Juan, R.Sikorski, S.Suggs, R.Radinsky Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26:1626-34; PMID:18316791; dx.doi.org/10.1200/JCO.2007.14.7116
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
Van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
Juan, T.7
Sikorski, R.8
Suggs, S.9
Radinsky, R.10
-
135
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
22149875
-
J.Baselga, J.Cortes, S.B.Kim, S.A.Im, R.Hegg, Y.H.Im, L.Roman, J.L.Pedrini, T.Pienkowski, A.Knott Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 2012; 366:109-19; PMID:22149875; dx.doi.org/10.1056/NEJMoa1113216
-
(2012)
N Engl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortes, J.2
Kim, S.B.3
Im, S.A.4
Hegg, R.5
Im, Y.H.6
Roman, L.7
Pedrini, J.L.8
Pienkowski, T.9
Knott, A.10
-
136
-
-
84855297353
-
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
-
22153890
-
L.Gianni, T.Pienkowski, Y.H.Im, L.Roman, L.M.Tseng, M.C.Liu, A.Lluch, E.Staroslawska, J.de la Haba-Rodriguez, S.A.Im Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol 2012; 13:25-32; PMID:22153890; dx.doi.org/10.1016/S1470-2045(11)70336-9
-
(2012)
Lancet Oncol
, vol.13
, pp. 25-32
-
-
Gianni, L.1
Pienkowski, T.2
Im, Y.H.3
Roman, L.4
Tseng, L.M.5
Liu, M.C.6
Lluch, A.7
Staroslawska, E.8
de la Haba-Rodriguez, J.9
Im, S.A.10
-
137
-
-
84859771379
-
Molecular mechanisms of cisplatin resistance
-
21892204
-
L.Galluzzi, L.Senovilla, I.Vitale, J.Michels, I.Martins, O.Kepp Molecular mechanisms of cisplatin resistance. Oncogene 2012; 31:1869-83; PMID:21892204; dx.doi.org/10.1038/onc.2011.384
-
(2012)
Oncogene
, vol.31
, pp. 1869-1883
-
-
Galluzzi, L.1
Senovilla, L.2
Vitale, I.3
Michels, J.4
Martins, I.5
Kepp, O.6
-
138
-
-
84865704717
-
Prognostic impact of vitamin B6 metabolism in lung cancer
-
22854025
-
L.Galluzzi, I.Vitale, L.Senovilla, K.A.Olaussen, G.Pinna, T.Eisenberg, A.Goubar, I.Martins, J.Michels, G.Kratassiouk Prognostic impact of vitamin B6 metabolism in lung cancer. Cell Rep 2012; 2:257-69; PMID:22854025; dx.doi.org/10.1016/j.celrep.2012.06.017
-
(2012)
Cell Rep
, vol.2
, pp. 257-269
-
-
Galluzzi, L.1
Vitale, I.2
Senovilla, L.3
Olaussen, K.A.4
Pinna, G.5
Eisenberg, T.6
Goubar, A.7
Martins, I.8
Michels, J.9
Kratassiouk, G.10
-
139
-
-
84880770534
-
Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study
-
23867211
-
S.Chawla, R.Henshaw, L.Seeger, E.Choy, J.Y.Blay, S.Ferrari, J.Kroep, R.Grimer, P.Reichardt, P.Rutkowski Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study. Lancet Oncol 2013; 14:901-8; PMID:23867211; dx.doi.org/10.1016/S1470-2045(13)70277-8
-
(2013)
Lancet Oncol
, vol.14
, pp. 901-908
-
-
Chawla, S.1
Henshaw, R.2
Seeger, L.3
Choy, E.4
Blay, J.Y.5
Ferrari, S.6
Kroep, J.7
Grimer, R.8
Reichardt, P.9
Rutkowski, P.10
-
140
-
-
84865073466
-
Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone
-
22711702
-
D.G.Branstetter, S.D.Nelson, J.C.Manivel, J.Y.Blay, S.Chawla, D.M.Thomas, S.Jun, I.Jacobs. Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone. Clin Cancer Res 2012; 18:4415-24; PMID:22711702; dx.doi.org/10.1158/1078-0432.CCR-12-0578
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4415-4424
-
-
Branstetter, D.G.1
Nelson, S.D.2
Manivel, J.C.3
Blay, J.Y.4
Chawla, S.5
Thomas, D.M.6
Jun, S.7
Jacobs, I.8
-
141
-
-
84856611805
-
Bone cancer in 2011: prevention and treatment of bone metastases
-
22182971
-
R.E.Coleman. Bone cancer in 2011: prevention and treatment of bone metastases. Nat Rev Clin Oncol 2012; 9:76-8; PMID:22182971; dx.doi.org/10.1038/nrclinonc.2011.198
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 76-78
-
-
Coleman, R.E.1
-
142
-
-
0033839790
-
Intravenous pamidronate in juvenile osteoporosis
-
10906023
-
N.J.Shaw, C.M.Boivin, N.J.Crabtree. Intravenous pamidronate in juvenile osteoporosis. Arch Dis Child 2000; 83:143-5; PMID:10906023; dx.doi.org/10.1136/adc.83.2.143
-
(2000)
Arch Dis Child
, vol.83
, pp. 143-145
-
-
Shaw, N.J.1
Boivin, C.M.2
Crabtree, N.J.3
-
143
-
-
0002761965
-
Cyclical pamidronate infusions in postmenopausal osteoporosis
-
8887311
-
A.Peretz, J.J.Body, J.C.Dumon, S.Rozenberg, A.Hotimski, J.P.Praet, M.Moris, H.Ham, P.Bergmann. Cyclical pamidronate infusions in postmenopausal osteoporosis. Maturitas 1996; 25:69-75; PMID:8887311; dx.doi.org/10.1016/0378-5122(96)01118-8
-
(1996)
Maturitas
, vol.25
, pp. 69-75
-
-
Peretz, A.1
Body, J.J.2
Dumon, J.C.3
Rozenberg, S.4
Hotimski, A.5
Praet, J.P.6
Moris, M.7
Ham, H.8
Bergmann, P.9
-
144
-
-
0033764107
-
Molecular remission of Philadelphia/bcr-abl-positive acute myeloid leukaemia after treatment with anti-CD33 calicheamicin conjugate (gemtuzumab ozogamicin, CMA-676)
-
11091212
-
M.P.de Vetten, J.H.Jansen, B.A.van der Reijden, M.S.Berger, J.M.Zijlmans, B.Lowenberg. Molecular remission of Philadelphia/bcr-abl-positive acute myeloid leukaemia after treatment with anti-CD33 calicheamicin conjugate (gemtuzumab ozogamicin, CMA-676). Br J Haematol 2000; 111:277-9; PMID:11091212; dx.doi.org/10.1046/j.1365-2141.2000.02402.x
-
(2000)
Br J Haematol
, vol.111
, pp. 277-279
-
-
de Vetten, M.P.1
Jansen, J.H.2
van der Reijden, B.A.3
Berger, M.S.4
Zijlmans, J.M.5
Lowenberg, B.6
-
145
-
-
0035397980
-
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse
-
11432892
-
E.L.Sievers, R.A.Larson, E.A.Stadtmauer, E.Estey, B.Lowenberg, H.Dombret, C.Karanes, M.Theobald, J.M.Bennett, M.L.Sherman Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. J Clin Oncol 2001; 19:3244-54; PMID:11432892
-
(2001)
J Clin Oncol
, vol.19
, pp. 3244-3254
-
-
Sievers, E.L.1
Larson, R.A.2
Stadtmauer, E.A.3
Estey, E.4
Lowenberg, B.5
Dombret, H.6
Karanes, C.7
Theobald, M.8
Bennett, J.M.9
Sherman, M.L.10
-
146
-
-
0034900174
-
Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia
-
11410481
-
P.F.Bross, J.Beitz, G.Chen, X.H.Chen, E.Duffy, L.Kieffer, S.Roy, R.Sridhara, A.Rahman, G.Williams Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res 2001; 7:1490-6; PMID:11410481
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1490-1496
-
-
Bross, P.F.1
Beitz, J.2
Chen, G.3
Chen, X.H.4
Duffy, E.5
Kieffer, L.6
Roy, S.7
Sridhara, R.8
Rahman, A.9
Williams, G.10
-
147
-
-
84863650195
-
RECRUIT-TandAbs: harnessing the immune system to kill cancer cells
-
22764766
-
F.McAleese, M.Eser. RECRUIT-TandAbs: harnessing the immune system to kill cancer cells. Future Oncol 2012; 8:687-95; PMID:22764766; dx.doi.org/10.2217/fon.12.54
-
(2012)
Future Oncol
, vol.8
, pp. 687-695
-
-
McAleese, F.1
Eser, M.2
-
148
-
-
84938731987
-
AFM11, a CD19/CD3 bispecific tandab, to facilitate T-cell-mediated killing of CD19+ cells
-
E.Zhukovsky, U.Reusch, C.Burkhardt, S.Knackmuss, I.Fucek, M.Eser AFM11, a CD19/CD3 bispecific tandab, to facilitate T-cell-mediated killing of CD19+ cells. ASCO Meeting Abstr 2013; 31:3068. Available: http://meetinglibrary.asco.org/content/115108-132
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 3068
-
-
Zhukovsky, E.1
Reusch, U.2
Burkhardt, C.3
Knackmuss, S.4
Fucek, I.5
Eser, M.6
-
149
-
-
84938731988
-
Preclinical development, primary and secondary phrmacodynamics, of the CD19/CD3 Tandab (AFM11)
-
E.Zhukovsky, S.Knackmuss, U.Reusch, C.Wall, K.Ellwanger, I.Fucek Preclinical development, primary and secondary phrmacodynamics, of the CD19/CD3 Tandab (AFM11). ASCO Meeting Abstr 2014; 32:e19546. Available: http://meetinglibrary.asco.org/content/133329-144
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 19546
-
-
Zhukovsky, E.1
Knackmuss, S.2
Reusch, U.3
Wall, C.4
Ellwanger, K.5
Fucek, I.6
-
150
-
-
39449125850
-
Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status
-
18253126
-
Y.Akashi, I.Okamoto, T.Iwasa, T.Yoshida, M.Suzuki, E.Hatashita, Y.Yamada, T.Satoh, M.Fukuoka, K.Ono Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status. Br J Cancer 2008; 98:749-55; PMID:18253126; dx.doi.org/10.1038/sj.bjc.6604222
-
(2008)
Br J Cancer
, vol.98
, pp. 749-755
-
-
Akashi, Y.1
Okamoto, I.2
Iwasa, T.3
Yoshida, T.4
Suzuki, M.5
Hatashita, E.6
Yamada, Y.7
Satoh, T.8
Fukuoka, M.9
Ono, K.10
-
151
-
-
45349101800
-
Phase I single-dose study of intracavitary-administered Nimotuzumab labeled with 188 Re in adult recurrent high-grade glioma
-
18094616
-
A.Casaco, G.Lopez, I.Garcia, J.A.Rodriguez, R.Fernandez, J.Figueredo, L.Torres, A.Perera, J.Batista, R.Leyva Phase I single-dose study of intracavitary-administered Nimotuzumab labeled with 188 Re in adult recurrent high-grade glioma. Cancer Biol Ther 2008; 7:333-9; PMID:18094616; dx.doi.org/10.4161/cbt.7.3.5414
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 333-339
-
-
Casaco, A.1
Lopez, G.2
Garcia, I.3
Rodriguez, J.A.4
Fernandez, R.5
Figueredo, J.6
Torres, L.7
Perera, A.8
Batista, J.9
Leyva, R.10
-
152
-
-
79954442316
-
Phase I clinical trial of the anti-EGFR monoclonal antibody nimotuzumab with concurrent external thoracic radiotherapy in Canadian patients diagnosed with stage IIb, III or IV non-small cell lung cancer unsuitable for radical therapy
-
20563810
-
G.Bebb, C.Smith, S.Rorke, W.Boland, L.Nicacio, R.Sukhoo, A.Brade. Phase I clinical trial of the anti-EGFR monoclonal antibody nimotuzumab with concurrent external thoracic radiotherapy in Canadian patients diagnosed with stage IIb, III or IV non-small cell lung cancer unsuitable for radical therapy. Cancer Chemother Pharmacol 2011; 67:837-45; PMID:20563810; dx.doi.org/10.1007/s00280-010-1379-9
-
(2011)
Cancer Chemother Pharmacol
, vol.67
, pp. 837-845
-
-
Bebb, G.1
Smith, C.2
Rorke, S.3
Boland, W.4
Nicacio, L.5
Sukhoo, R.6
Brade, A.7
-
153
-
-
74549174584
-
Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patients with advanced solid tumors
-
20068101
-
M.S.Gordon, C.S.Sweeney, D.S.Mendelson, S.G.Eckhardt, A.Anderson, D.M.Beaupre, D.Branstetter, T.L.Burgess, A.Coxon, H.Deng Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patients with advanced solid tumors. Clin Cancer Res 2010; 16:699-710; PMID:20068101; dx.doi.org/10.1158/1078-0432.CCR-09-1365
-
(2010)
Clin Cancer Res
, vol.16
, pp. 699-710
-
-
Gordon, M.S.1
Sweeney, C.S.2
Mendelson, D.S.3
Eckhardt, S.G.4
Anderson, A.5
Beaupre, D.M.6
Branstetter, D.7
Burgess, T.L.8
Coxon, A.9
Deng, H.10
-
154
-
-
36749042647
-
AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts
-
18006775
-
H.T.Jun, J.Sun, K.Rex, R.Radinsky, R.Kendall, A.Coxon, T.L.Burgess. AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts. Clin Cancer Res 2007; 13:6735-42; PMID:18006775; dx.doi.org/10.1158/1078-0432.CCR-06-2969
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6735-6742
-
-
Jun, H.T.1
Sun, J.2
Rex, K.3
Radinsky, R.4
Kendall, R.5
Coxon, A.6
Burgess, T.L.7
-
155
-
-
34548561684
-
Pharmacokinetics and safety of a fully human hepatocyte growth factor antibody, AMG 102, in cynomolgus monkeys
-
17520181
-
T.Kakkar, M.Ma, Y.Zhuang, A.Patton, Z.Hu, B.Mounho. Pharmacokinetics and safety of a fully human hepatocyte growth factor antibody, AMG 102, in cynomolgus monkeys. Pharm Res 2007; 24:1910-8; PMID:17520181; dx.doi.org/10.1007/s11095-007-9316-2
-
(2007)
Pharm Res
, vol.24
, pp. 1910-1918
-
-
Kakkar, T.1
Ma, M.2
Zhuang, Y.3
Patton, A.4
Hu, Z.5
Mounho, B.6
-
156
-
-
84869477687
-
Erlotinib antagonizes ABC transporters in acute myeloid leukemia
-
23095522
-
E.Lainey, M.Sebert, S.Thepot, M.Scoazec, C.Bouteloup, C.Leroy, S.De Botton, L.Galluzzi, P.Fenaux, G.Kroemer. Erlotinib antagonizes ABC transporters in acute myeloid leukemia. Cell Cycle 2012; 11:4079-92; PMID:23095522; dx.doi.org/10.4161/cc.22382
-
(2012)
Cell Cycle
, vol.11
, pp. 4079-4092
-
-
Lainey, E.1
Sebert, M.2
Thepot, S.3
Scoazec, M.4
Bouteloup, C.5
Leroy, C.6
De Botton, S.7
Galluzzi, L.8
Fenaux, P.9
Kroemer, G.10
-
157
-
-
41349111281
-
Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study
-
17925489
-
S.Boehrer, L.Ades, T.Braun, L.Galluzzi, J.Grosjean, C.Fabre, G.Le Roux, C.Gardin, A.Martin, S.de Botton Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study. Blood 2008; 111:2170-80; PMID:17925489; dx.doi.org/10.1182/blood-2007-07-100362
-
(2008)
Blood
, vol.111
, pp. 2170-2180
-
-
Boehrer, S.1
Ades, L.2
Braun, T.3
Galluzzi, L.4
Grosjean, J.5
Fabre, C.6
Le Roux, G.7
Gardin, C.8
Martin, A.9
de Botton, S.10
-
158
-
-
84891868719
-
Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody ublituximab on chronic lymphocytic leukemia cells with the 17p deletion
-
23958919
-
Le M.Garff-Tavernier, L.Herbi, C.de Romeuf, F.Nguyen-Khac, F.Davi, A.Grelier, M.Boudjoghra, K.Maloum, S.Choquet, R.Urbain Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody ublituximab on chronic lymphocytic leukemia cells with the 17p deletion. Leukemia 2014; 28:230-3; PMID:23958919; dx.doi.org/10.1038/leu.2013.240
-
(2014)
Leukemia
, vol.28
, pp. 230-233
-
-
Garff-Tavernier, M.1
Herbi, L.2
de Romeuf, C.3
Nguyen-Khac, F.4
Davi, F.5
Grelier, A.6
Boudjoghra, M.7
Maloum, K.8
Choquet, S.9
Urbain, R.10
-
159
-
-
84883589236
-
Preclinical study of Ublituximab, a Glycoengineered anti-human CD20 antibody, in murine models of primary cerebral and intraocular B-cell lymphomas
-
23611989
-
Ben R.Abdelwahed, S.Donnou, H.Ouakrim, L.Crozet, J.Cosette, A.Jacquet, I.Tourais, B.Fournès, M.Gillard Bocquet, A.Miloudi Preclinical study of Ublituximab, a Glycoengineered anti-human CD20 antibody, in murine models of primary cerebral and intraocular B-cell lymphomas. Invest Ophthalmol Vis Sci 2013; 54:3657-65; PMID:23611989; dx.doi.org/10.1167/iovs.12-10316
-
(2013)
Invest Ophthalmol Vis Sci
, vol.54
, pp. 3657-3665
-
-
Abdelwahed, R.1
Donnou, S.2
Ouakrim, H.3
Crozet, L.4
Cosette, J.5
Jacquet, A.6
Tourais, I.7
Fournès, B.8
Gillard Bocquet, M.9
Miloudi, A.10
-
160
-
-
84917690659
-
LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth
-
25231402
-
L.Liu, W.Zeng, M.A.Wortinger, S.C.Yan, P.D.Cornwell, V.L.Peek, J.R.Stephens, J.W.Tetreault, J.Xia, J.R.Manro LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth. Clin Cancer Res 2014; 20:6059-70; PMID:25231402; dx.doi.org/10.1158/1078-0432.CCR-14-0543
-
(2014)
Clin Cancer Res
, vol.20
, pp. 6059-6070
-
-
Liu, L.1
Zeng, W.2
Wortinger, M.A.3
Yan, S.C.4
Cornwell, P.D.5
Peek, V.L.6
Stephens, J.R.7
Tetreault, J.W.8
Xia, J.9
Manro, J.R.10
-
161
-
-
70350494468
-
Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma
-
19633198
-
D.Dornan, F.Bennett, Y.Chen, M.Dennis, D.Eaton, K.Elkins, D.French, M.A.Go, A.Jack, J.R.Junutula Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma. Blood 2009; 114:2721-9; PMID:19633198; dx.doi.org/10.1182/blood-2009-02-205500
-
(2009)
Blood
, vol.114
, pp. 2721-2729
-
-
Dornan, D.1
Bennett, F.2
Chen, Y.3
Dennis, M.4
Eaton, D.5
Elkins, K.6
French, D.7
Go, M.A.8
Jack, A.9
Junutula, J.R.10
-
162
-
-
34547131841
-
Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma
-
17374736
-
A.G.Polson, S.F.Yu, K.Elkins, B.Zheng, S.Clark, G.S.Ingle, D.S.Slaga, L.Giere, C.Du, C.Tan Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma. Blood 2007; 110:616-23; PMID:17374736; dx.doi.org/10.1182/blood-2007-01-066704
-
(2007)
Blood
, vol.110
, pp. 616-623
-
-
Polson, A.G.1
Yu, S.F.2
Elkins, K.3
Zheng, B.4
Clark, S.5
Ingle, G.S.6
Slaga, D.S.7
Giere, L.8
Du, C.9
Tan, C.10
-
163
-
-
77954663766
-
Bendamustine: something old, something new
-
20376452
-
N.Tageja, J.Nagi. Bendamustine: something old, something new. Cancer Chemother Pharmacol 2010; 66:413-23; PMID:20376452; dx.doi.org/10.1007/s00280-010-1317-x
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 413-423
-
-
Tageja, N.1
Nagi, J.2
-
164
-
-
8944242603
-
Phase Ia/Ib trial of anti-GD2 chimeric monoclonal antibody 14.18 (ch14.18) and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in metastatic melanoma
-
8811495
-
J.L.Murray, E.S.Kleinerman, S.F.Jia, M.G.Rosenblum, O.Eton, A.Buzaid, S.Legha, M.I.Ross, L.Thompson, K.Mujoo Phase Ia/Ib trial of anti-GD2 chimeric monoclonal antibody 14.18 (ch14.18) and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in metastatic melanoma. J Immunother Emphasis Tumor Immunol 1996; 19:206-17; PMID:8811495; dx.doi.org/10.1097/00002371-199605000-00005
-
(1996)
J Immunother Emphasis Tumor Immunol
, vol.19
, pp. 206-217
-
-
Murray, J.L.1
Kleinerman, E.S.2
Jia, S.F.3
Rosenblum, M.G.4
Eton, O.5
Buzaid, A.6
Legha, S.7
Ross, M.I.8
Thompson, L.9
Mujoo, K.10
-
165
-
-
0034671441
-
Phase I study of chimeric human/murine anti-ganglioside G(D2) monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: a Children's Cancer Group Study
-
11118469
-
M.F.Ozkaynak, P.M.Sondel, M.D.Krailo, J.Gan, B.Javorsky, R.A.Reisfeld, K.K.Matthay, G.H.Reaman, R.C.Seeger. Phase I study of chimeric human/murine anti-ganglioside G(D2) monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: a Children's Cancer Group Study. J Clin Oncol 2000; 18:4077-85; PMID:11118469
-
(2000)
J Clin Oncol
, vol.18
, pp. 4077-4085
-
-
Ozkaynak, M.F.1
Sondel, P.M.2
Krailo, M.D.3
Gan, J.4
Javorsky, B.5
Reisfeld, R.A.6
Matthay, K.K.7
Reaman, G.H.8
Seeger, R.C.9
-
166
-
-
77957341503
-
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma
-
20879881
-
A.L.Yu, A.L.Gilman, M.F.Ozkaynak, W.B.London, S.G.Kreissman, H.X.Chen, M.Smith, B.Anderson, J.G.Villablanca, K.K.Matthay Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med 2010; 363:1324-34; PMID:20879881; dx.doi.org/10.1056/NEJMoa0911123
-
(2010)
N Engl J Med
, vol.363
, pp. 1324-1334
-
-
Yu, A.L.1
Gilman, A.L.2
Ozkaynak, M.F.3
London, W.B.4
Kreissman, S.G.5
Chen, H.X.6
Smith, M.7
Anderson, B.8
Villablanca, J.G.9
Matthay, K.K.10
-
167
-
-
78651428141
-
Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy
-
21244693
-
T.Simon, B.Hero, A.Faldum, R.Handgretinger, M.Schrappe, T.Klingebiel, F.Berthold. Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy. BMC Cancer 2011; 11:21; PMID:21244693; dx.doi.org/10.1186/1471-2407-11-21
-
(2011)
BMC Cancer
, vol.11
, pp. 21
-
-
Simon, T.1
Hero, B.2
Faldum, A.3
Handgretinger, R.4
Schrappe, M.5
Klingebiel, T.6
Berthold, F.7
-
168
-
-
84886945545
-
Anti-GD2 antibody 3F8 and barley-derived (1 -> 3),(1 -> 4)-beta-glucan: a phase I study in patients with chemoresistant neuroblastoma
-
23802080
-
S.Modak, B.H.Kushner, K.Kramer, A.Vickers, I.Y.Cheung, N.K.Cheung. Anti-GD2 antibody 3F8 and barley-derived (1 -> 3),(1 -> 4)-beta-glucan: a phase I study in patients with chemoresistant neuroblastoma. Oncoimmunology 2013; 2:e23402; PMID:23802080
-
(2013)
Oncoimmunology
, vol.2
, pp. 23402
-
-
Modak, S.1
Kushner, B.H.2
Kramer, K.3
Vickers, A.4
Cheung, I.Y.5
Cheung, N.K.6
-
169
-
-
84877799310
-
Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo
-
22754766
-
N.K.Cheung, H.Guo, J.Hu, D.V.Tassev, I.Y.Cheung. Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo. Oncoimmunology 2012; 1:477-86; PMID:22754766; dx.doi.org/10.4161/onci.19864
-
(2012)
Oncoimmunology
, vol.1
, pp. 477-486
-
-
Cheung, N.K.1
Guo, H.2
Hu, J.3
Tassev, D.V.4
Cheung, I.Y.5
-
170
-
-
84886943238
-
Trial watch: immunostimulatory cytokines
-
24073369
-
E.Vacchelli, A.Eggermont, W.H.Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: immunostimulatory cytokines. Oncoimmunology 2013; 2:e24850; PMID:24073369; dx.doi.org/10.4161/onci.24850
-
(2013)
Oncoimmunology
, vol.2
, pp. 24850
-
-
Vacchelli, E.1
Eggermont, A.2
Fridman, W.H.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
171
-
-
84906489918
-
Trial watch: immunostimulatory cytokines in cancer therapy
-
25083328
-
E.Vacchelli, F.Aranda, F.Obrist, A.Eggermont, J.Galon, I.Cremer, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: immunostimulatory cytokines in cancer therapy. Oncoimmunology 2014; 3:e29030; PMID:25083328; dx.doi.org/10.4161/onci.29030
-
(2014)
Oncoimmunology
, vol.3
, pp. 29030
-
-
Vacchelli, E.1
Aranda, F.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Cremer, I.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
172
-
-
84880380678
-
A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology
-
23808985
-
S.C.Jeffrey, P.J.Burke, R.P.Lyon, D.W.Meyer, D.Sussman, M.Anderson, J.H.Hunter, C.I.Leiske, J.B.Miyamoto, N.D.Nicholas A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem 2013; 24:1256-63; PMID:23808985; dx.doi.org/10.1021/bc400217g
-
(2013)
Bioconjug Chem
, vol.24
, pp. 1256-1263
-
-
Jeffrey, S.C.1
Burke, P.J.2
Lyon, R.P.3
Meyer, D.W.4
Sussman, D.5
Anderson, M.6
Hunter, J.H.7
Leiske, C.I.8
Miyamoto, J.B.9
Nicholas, N.D.10
-
173
-
-
84995380134
-
Effects of conventional therapeutic interventions on the number and function of regulatory T cells
-
24353914
-
M.Roselli, V.Cereda, M.G.di Bari, V.Formica, A.Spila, C.Jochems, B.Farsaci, R.Donahue, J.L.Gulley, J.Schlom Effects of conventional therapeutic interventions on the number and function of regulatory T cells. Oncoimmunology 2013; 2:e27025; PMID:24353914; dx.doi.org/10.4161/onci.27025
-
(2013)
Oncoimmunology
, vol.2
, pp. 27025
-
-
Roselli, M.1
Cereda, V.2
di Bari, M.G.3
Formica, V.4
Spila, A.5
Jochems, C.6
Farsaci, B.7
Donahue, R.8
Gulley, J.L.9
Schlom, J.10
-
174
-
-
77954700380
-
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
20498403
-
D.W.Miles, A.Chan, L.Y.Dirix, J.Cortes, X.Pivot, P.Tomczak, T.Delozier, J.H.Sohn, L.Provencher, F.Puglisi Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2010; 28:3239-47; PMID:20498403; dx.doi.org/10.1200/JCO.2008.21.6457
-
(2010)
J Clin Oncol
, vol.28
, pp. 3239-3247
-
-
Miles, D.W.1
Chan, A.2
Dirix, L.Y.3
Cortes, J.4
Pivot, X.5
Tomczak, P.6
Delozier, T.7
Sohn, J.H.8
Provencher, L.9
Puglisi, F.10
-
175
-
-
84858797619
-
Trial watch: monoclonal antibodies in cancer therapy
-
22720209
-
L.Galluzzi, E.Vacchelli, W.H.Fridman, J.Galon, C.Sautes-Fridman, E.Tartour, J.Zucman-Rossi, L.Zitvogel, G.Kroemer. Trial watch: monoclonal antibodies in cancer therapy. Oncoimmunology 2012; 1:28-37; PMID:22720209; dx.doi.org/10.4161/onci.1.1.17938
-
(2012)
Oncoimmunology
, vol.1
, pp. 28-37
-
-
Galluzzi, L.1
Vacchelli, E.2
Fridman, W.H.3
Galon, J.4
Sautes-Fridman, C.5
Tartour, E.6
Zucman-Rossi, J.7
Zitvogel, L.8
Kroemer, G.9
-
176
-
-
66849140937
-
AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells
-
19366899
-
P.J.Beltran, P.Mitchell, Y.A.Chung, E.Cajulis, J.Lu, B.Belmontes, J.Ho, M.M.Tsai, M.Zhu, S.Vonderfecht AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells. Mol Cancer Ther 2009; 8:1095-105; PMID:19366899; dx.doi.org/10.1158/1535-7163.MCT-08-1171
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1095-1105
-
-
Beltran, P.J.1
Mitchell, P.2
Chung, Y.A.3
Cajulis, E.4
Lu, J.5
Belmontes, B.6
Ho, J.7
Tsai, M.M.8
Zhu, M.9
Vonderfecht, S.10
-
177
-
-
84875552922
-
Immunogenic cell death in cancer therapy
-
23157435
-
G.Kroemer, L.Galluzzi, O.Kepp, L.Zitvogel. Immunogenic cell death in cancer therapy. Annu Rev Immunol 2013; 31:51-72; PMID:23157435; dx.doi.org/10.1146/annurev-immunol-032712-100008
-
(2013)
Annu Rev Immunol
, vol.31
, pp. 51-72
-
-
Kroemer, G.1
Galluzzi, L.2
Kepp, O.3
Zitvogel, L.4
-
178
-
-
84885692390
-
Trial watch: chemotherapy with immunogenic cell death inducers
-
23687621
-
E.Vacchelli, L.Senovilla, A.Eggermont, W.H.Fridman, J.Galon, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: chemotherapy with immunogenic cell death inducers. Oncoimmunology 2013; 2:e23510; PMID:23687621; dx.doi.org/10.4161/onci.23510
-
(2013)
Oncoimmunology
, vol.2
, pp. 23510
-
-
Vacchelli, E.1
Senovilla, L.2
Eggermont, A.3
Fridman, W.H.4
Galon, J.5
Zitvogel, L.6
Kroemer, G.7
Galluzzi, L.8
-
179
-
-
84863678237
-
Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: results of a phase II study
-
22614995
-
B.Pro, R.Advani, P.Brice, N.L.Bartlett, J.D.Rosenblatt, T.Illidge, J.Matous, R.Ramchandren, M.Fanale, J.M.Connors Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: results of a phase II study. J Clin Oncol 2012; 30:2190-6; PMID:22614995; dx.doi.org/10.1200/JCO.2011.38.0402
-
(2012)
J Clin Oncol
, vol.30
, pp. 2190-2196
-
-
Pro, B.1
Advani, R.2
Brice, P.3
Bartlett, N.L.4
Rosenblatt, J.D.5
Illidge, T.6
Matous, J.7
Ramchandren, R.8
Fanale, M.9
Connors, J.M.10
-
181
-
-
84898430937
-
A phase II, open-label study evaluating the safety and efficacy of ramucirumab combined with mFOLFOX-6 as first-line therapy in patients (pts) with metastatic colorectal cancer (mCRC): CP12-0709/NCT00862784
-
24674871
-
R.Garcia-Carbonero, F.Rivera, J.Maurel, J.-P.M.Ayoub, M.J.Moore, A.Cervantes-Ruiperez, T.R.Asmis, J.D.Schwartz, F.Nasroulah, S.Ballal A phase II, open-label study evaluating the safety and efficacy of ramucirumab combined with mFOLFOX-6 as first-line therapy in patients (pts) with metastatic colorectal cancer (mCRC): CP12-0709/NCT00862784. ASCO Meeting Abstracts 2012; 30:533; PMID:24674871; dx.doi.org/10.1634/theoncologist.2014-0028
-
(2012)
ASCO Meeting Abstracts
, vol.30
, pp. 533
-
-
Garcia-Carbonero, R.1
Rivera, F.2
Maurel, J.3
Ayoub, J.-P.M.4
Moore, M.J.5
Cervantes-Ruiperez, A.6
Asmis, T.R.7
Schwartz, J.D.8
Nasroulah, F.9
Ballal, S.10
-
182
-
-
84904069004
-
A phase (Ph) Ib study of irinotecan (IRI), levofolinate (LV), and 5-fluorouracil (5-FU) (FOLFIRI) plus ramucirumab (RAM; IMC-1121B) drug product in Japanese (JP) patients (pts) with metastatic colorectal carcinoma (mCRC) progressive during or following first-line therapy with bevacizumab (BEV), oxaliplatin (OXALI), and a fluoropyrimidine (FP) (CP12-1029/NCT01286818)
-
T.Yoshino, K.Yamazaki, M.Yoshida, M.D.Rutstein, N.Yoshizuka, A.Ohtsu. A phase (Ph) Ib study of irinotecan (IRI), levofolinate (LV), and 5-fluorouracil (5-FU) (FOLFIRI) plus ramucirumab (RAM; IMC-1121B) drug product in Japanese (JP) patients (pts) with metastatic colorectal carcinoma (mCRC) progressive during or following first-line therapy with bevacizumab (BEV), oxaliplatin (OXALI), and a fluoropyrimidine (FP) (CP12-1029/NCT01286818). ASCO Meeting Abstr 2013; 31:591.
-
(2013)
ASCO Meeting Abstr
, vol.31
, pp. 591
-
-
Yoshino, T.1
Yamazaki, K.2
Yoshida, M.3
Rutstein, M.D.4
Yoshizuka, N.5
Ohtsu, A.6
-
183
-
-
78751525051
-
Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions
-
21127197
-
M.J.Towle, K.A.Salvato, B.F.Wels, K.K.Aalfs, W.Zheng, B.M.Seletsky, X.Zhu, B.M.Lewis, Y.Kishi, M.J.Yu Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res 2011; 71:496-505; PMID:21127197; dx.doi.org/10.1158/0008-5472.CAN-10-1874
-
(2011)
Cancer Res
, vol.71
, pp. 496-505
-
-
Towle, M.J.1
Salvato, K.A.2
Wels, B.F.3
Aalfs, K.K.4
Zheng, W.5
Seletsky, B.M.6
Zhu, X.7
Lewis, B.M.8
Kishi, Y.9
Yu, M.J.10
-
184
-
-
4143052665
-
Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389
-
15313917
-
G.Kuznetsov, M.J.Towle, H.Cheng, T.Kawamura, K.TenDyke, D.Liu, Y.Kishi, M.J.Yu, B.A.Littlefield. Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389. Cancer Res 2004; 64:5760-6; PMID:15313917; dx.doi.org/10.1158/0008-5472.CAN-04-1169
-
(2004)
Cancer Res
, vol.64
, pp. 5760-5766
-
-
Kuznetsov, G.1
Towle, M.J.2
Cheng, H.3
Kawamura, T.4
TenDyke, K.5
Liu, D.6
Kishi, Y.7
Yu, M.J.8
Littlefield, B.A.9
-
185
-
-
84908278800
-
Final results of a phase 2 study of ramucirumab (RAM) plus eribulin (E) versus E in advanced metastatic breast cancer (MBC)
-
D.A.Yardley, P.D.Richards, J.A.Reeves, E.C.Dees, C.R.C.Osborne, H.H.Soliman Final results of a phase 2 study of ramucirumab (RAM) plus eribulin (E) versus E in advanced metastatic breast cancer (MBC). ASCO Meeting Abstr 2014; 32:1035. Available: http://meetinglibrary.asco.org/content/126127-144
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 1035
-
-
Yardley, D.A.1
Richards, P.D.2
Reeves, J.A.3
Dees, E.C.4
Osborne, C.R.C.5
Soliman, H.H.6
-
186
-
-
84907687048
-
Phase II study evaluating the effect of concomitant ramucirumab (IMC-1121B; RAM) on the pharmacokinetics (PK) of docetaxel (DOC) in patients (pts) with advanced malignant solid tumors
-
M.N.Stein, L.Q.M.Chow, D.C.Smith, D.R.Shepard, D.Wang, J.D.Powderly Phase II study evaluating the effect of concomitant ramucirumab (IMC-1121B; RAM) on the pharmacokinetics (PK) of docetaxel (DOC) in patients (pts) with advanced malignant solid tumors. ASCO Meeting Abstr 2014; 32:e13539.Available: http://meetinglibrary.asco.org/content/126489-144
-
(2014)
ASCO Meeting Abstr
, vol.32
, pp. 13539
-
-
Stein, M.N.1
Chow, L.Q.M.2
Smith, D.C.3
Shepard, D.R.4
Wang, D.5
Powderly, J.D.6
-
187
-
-
84871120189
-
Monoclonal antibodies: magic bullets with a hefty price tag
-
23236036
-
A.F.Shaughnessy. Monoclonal antibodies: magic bullets with a hefty price tag. BMJ 2012; 345:e8346; PMID:23236036; dx.doi.org/10.1136/bmj.e8346
-
(2012)
BMJ
, vol.345
, pp. 8346
-
-
Shaughnessy, A.F.1
-
188
-
-
84902593489
-
Trial watch: DNA vaccines for cancer therapy
-
24800178
-
J.Pol, N.Bloy, F.Obrist, A.Eggermont, J.Galon, W.Herve Fridman, I.Cremer, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: DNA vaccines for cancer therapy. Oncoimmunology 2014; 3:e28185; PMID:24800178; dx.doi.org/10.4161/onci.28185
-
(2014)
Oncoimmunology
, vol.3
, pp. 28185
-
-
Pol, J.1
Bloy, N.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Herve Fridman, W.6
Cremer, I.7
Zitvogel, L.8
Kroemer, G.9
Galluzzi, L.10
-
189
-
-
84894553314
-
Trial watch: peptide vaccines in cancer therapy
-
24498550
-
F.Aranda, E.Vacchelli, A.Eggermont, J.Galon, C.Sautes-Fridman, E.Tartour, L.Zitvogel, G.Kroemer, L.Galluzzi. Trial watch: peptide vaccines in cancer therapy. Oncoimmunology 2013; 2:e26621; PMID:24498550; dx.doi.org/10.4161/onci.26621
-
(2013)
Oncoimmunology
, vol.2
, pp. 26621
-
-
Aranda, F.1
Vacchelli, E.2
Eggermont, A.3
Galon, J.4
Sautes-Fridman, C.5
Tartour, E.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
-
190
-
-
77953678688
-
Understanding and circumventing resistance to anticancer monoclonal antibodies
-
20065642
-
L.Reslan, S.Dalle, C.Dumontet. Understanding and circumventing resistance to anticancer monoclonal antibodies. MAbs 2009; 1:222-9; PMID:20065642; dx.doi.org/10.4161/mabs.1.3.8292
-
(2009)
MAbs
, vol.1
, pp. 222-229
-
-
Reslan, L.1
Dalle, S.2
Dumontet, C.3
-
191
-
-
84857139331
-
Monoclonal antibodies for the treatment of cancer
-
22245472
-
C.W.Shuptrine, R.Surana, L.M.Weiner. Monoclonal antibodies for the treatment of cancer. Semin Cancer Biol 2012; 22:3-13; PMID:22245472; dx.doi.org/10.1016/j.semcancer.2011.12.009
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 3-13
-
-
Shuptrine, C.W.1
Surana, R.2
Weiner, L.M.3
-
192
-
-
84858785688
-
Antibody therapy of cancer
-
22437872
-
A.M.Scott, J.D.Wolchok, L.J.Old. Antibody therapy of cancer. Nat Rev Cancer 2012; 12:278-87; PMID:22437872; dx.doi.org/10.1038/nrc3236
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 278-287
-
-
Scott, A.M.1
Wolchok, J.D.2
Old, L.J.3
-
193
-
-
77950517325
-
The safety and side effects of monoclonal antibodies
-
20305665
-
T.T.Hansel, H.Kropshofer, T.Singer, J.A.Mitchell, A.J.George. The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov 2010; 9:325-38; PMID:20305665; dx.doi.org/10.1038/nrd3003
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 325-338
-
-
Hansel, T.T.1
Kropshofer, H.2
Singer, T.3
Mitchell, J.A.4
George, A.J.5
|