Novel sesquiterpene lactone analogues as potent anti-breast cancer agents

Molecular Oncology

Volumn 10, Issue 6, 2016, Pages 921-937

  Nakagawa Goto, Kyoko ^a,b   Chen, Jo Yu ^c   Cheng, Yu Ting ^d,e,f   Lee, Wai Leng ^g   Takeya, Munehisa ^a   Saito, Yohei ^a   Lee, Kuo Hsiung ^b,h   Shyur, Lie Fen ^c,d,e  

^a KANAZAWA UNIVERSITY   (Japan)

^b University of North Carolina   (United States)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d ACADEMIA SINICA   (Taiwan)

^e AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^f NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^g MONASH UNIVERSITY MALAYSIA   (Malaysia)

^h CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Deoxyelephantopin; DET derivatives; Lung metastasis; Paclitaxel; Triple negative breast cancer

Indexed keywords

ACTIN; CYCLOOXYGENASE 2; DEOXYELEPHANTOPIN; DEOXYELEPHANTOPIN 35; KI 67 ANTIGEN; PACLITAXEL; PROTEIN PN 1; PROTEIN ZO1; SESQUITERPENE LACTONE DERIVATIVE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN; VIMENTIN; ANTINEOPLASTIC AGENT; LACTONE; SESQUITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CELL MIGRATION; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; M PHASE CELL CYCLE CHECKPOINT; MDA MB 231 CELL LINE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCID MOUSE; STRUCTURE ACTIVITY RELATION; TRIPLE NEGATIVE BREAST CANCER; TUMOR INVASION; TUMOR XENOGRAFT; ANIMAL; BREAST; CELL CYCLE; CELL LINE; CELL MOTION; CHEMISTRY; DRUG EFFECTS; MOLECULAR MODEL; NEOPLASM METASTASIS; PATHOLOGY; SYNTHESIS; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CRYSTALLOGRAPHY, X-RAY; FEMALE; LACTONES; MICE; MICE, SCID; MODELS, MOLECULAR; NEOPLASM METASTASIS; SESQUITERPENES; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84962440778     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2016.03.002     Document Type: Article

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