Differential proteomic profiling identifies novel molecular targets of paclitaxel and phytoagent deoxyelephantopin against mammary adenocarcinoma cells

Journal of Proteome Research

Volumn 9, Issue 1, 2010, Pages 237-253

  Lee, Wai Leng ^a,b,c   Wen, Tuan Nan ^d   Shiau, Jeng Yuan ^b   Shyur, Lie Fen ^b,c  

^a Taiwan International Graduate Program   (Taiwan)

^b AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^d INSTITUTE OF PLANT AND MICROBIAL BIOLOGY   (Taiwan)

Author keywords

Apoptosis; Deoxyelephantopin; DIGE 2 D electrophoresis; Endoplasmic reticulum stress; Mammary adenocarcinoma; Paclitaxel; Proteasome inhibitor; Therapeutic agents; TS A cells

Indexed keywords

CASPASE 12; CASPASE 3; DEOXYELEPHANTOPIN; GERMACRANOLIDE DERIVATIVE; GLUCOSE REGULATED PROTEIN 78; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PROTEASOME; SESQUITERPENE DERIVATIVE; THIOREDOXIN; THIOREDOXIN DOMAIN CONTAINING PROTEIN 5; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CALCIUM TRANSPORT; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DRUG EFFICACY; DRUG STRUCTURE; ELEPHANTOPUS SCABER; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; MEDICINAL PLANT; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEOMICS; WESTERN BLOTTING;

ADENOCARCINOMA; AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOPLASMIC RETICULUM; HUMANS; LACTONES; MAMMARY GLANDS, HUMAN; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MOLECULAR SEQUENCE DATA; PACLITAXEL; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOMICS; SESQUITERPENES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; UBIQUITIN;

ANIMALIA; ELEPHANTOPUS SCABER; MURINAE; MUS;

EID: 73649090040     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr900543e     Document Type: Article

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