Bioassay-guided isolation of a sesquiterpene lactone of deoxyelephantopin from Elephantopus scaber Linn. active on Trypanosome brucei rhodesience

Phytomedicine

Volumn 21, Issue 3, 2014, Pages 282-285

  Zahari, Zuriati ^a   Jani, Nor Akmalazura ^b   Amanah, Azimah ^a   Latif, Mohd Naffidi Abdul ^a   Majid, Mohamed Isa Abdul ^c   Adenan, Mohd Ilham ^a,d  

^a Kemeneterian Sains Teknologi dan Inovasi   (Malaysia)

^b UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^c SCHOOL OF PHYSICS   (Malaysia)

^d FOREST RESEARCH INSTITUTE MALAYSIA   (Malaysia)

Author keywords

Bioassay guided isolation; Deoxyelephantopin; Elephantopus scaber; Trypanosome brucei rhodesience; Trypanosomiasis

Indexed keywords

ANTITRYPANOSOMAL AGENT; DEOXYELEPHANTOPIN; MELARSOPROL; PENTAMIDINE; PLANT EXTRACT; SESQUITERPENE LACTONE; UNCLASSIFIED DRUG; LACTONE; SESQUITERPENE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOASSAY; CYTOTOXICITY; DRUG ISOLATION; ELEPHANTOPUS SCABER; IC 50; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI; TRYPANOSOME BRUCEI RHODESIENCE; AFRICAN TRYPANOSOMIASIS; ANIMAL; ASTERACEAE; CHEMISTRY; DRUG EFFECTS; IC50; MOUSE; PARASITOLOGY; TRYPANOSOMA RHODESIENSE;

ELEPHANTOPUS SCABER;

ANIMALS; ASTERACEAE; INHIBITORY CONCENTRATION 50; LACTONES; MICE; PLANT EXTRACTS; SESQUITERPENES; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMIASIS, AFRICAN;

EID: 84896489921     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.09.011     Document Type: Article

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