Hepatoprotective effect and mechanistic insights of deoxyelephantopin, a phyto-sesquiterpene lactone, against fulminant hepatitis

Journal of Nutritional Biochemistry

Volumn 24, Issue 3, 2013, Pages 516-530

  Huang, Chi Chang ^a   Lin, Kun Ju ^b   Cheng, Ya Wen ^a   Hsu, Chih An ^a   Yang, Sien Sing ^c   Shyur, Lie Fen ^a,d  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CATHAY GENERAL HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Deoxyelephantopin; DISIDA; Elephantopus scaber; Fulminant hepatic failure; Hepatobiliary scintigraphy; Hepatoprotection

Indexed keywords

3 NITROTYROSINE; AMINOTRANSFERASE; CYCLOOXYGENASE 2; DEOXYELEPHANTOPIN; GELATINASE B; HEME OXYGENASE 1; INTERLEUKIN 6; SESQUITERPENE LACTONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; DRUG EXCRETION; DRUG UPTAKE; ELEPHANTOPUS SCABER; ENZYME ACTIVITY; ENZYME INHIBITION; HEPATITIS; IN VIVO STUDY; LIVER PROTECTION; LIVER SCINTISCANNING; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THERAPY EFFECT;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; GALACTOSAMINE; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HEPATITIS; INTERLEUKIN-6; LACTONES; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE, ACUTE; MALE; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASE 8; NF-KAPPA B; PHOSPHORYLATION; SESQUITERPENES; STAT3 TRANSCRIPTION FACTOR; TRANSAMINASES; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE; UP-REGULATION;

ANIMALIA; ELEPHANTOPUS SCABER; MUS;

EID: 84875515741     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2012.01.013     Document Type: Article

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