Deoxyelephantopin, a novel multifunctional agent, suppresses mammary tumour growth and lung metastasis and doubles survival time in mice

British Journal of Pharmacology

Volumn 159, Issue 4, 2010, Pages 856-871

  Huang, Chi Chang ^a   Lo, Chiu Ping ^a   Chiu, Chih Yang ^a   Shyur, Lie Fen ^a,b  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Chemoprevention; Deoxyelephantopin; Elephantopus scaber; Lung metastasis; Mammary adenocarcinoma

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLOOXYGENASE 2; DEOXYELEPHANTOPIN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; REACTIVE OXYGEN METABOLITE; SESQUITERPENE LACTONE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE ARREST; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; DRUG EFFICACY; DRUG MECHANISM; FEMALE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR MODEL;

ADENOCARCINOMA; ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; APOPTOSIS; BREAST NEOPLASMS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LACTONES; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NF-KAPPA B; PACLITAXEL; REACTIVE OXYGEN SPECIES; SESQUITERPENES; TIME FACTORS; TUMOR BURDEN; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77249177609     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00581.x     Document Type: Article

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