The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design

Antiviral Research

Volumn 130, Issue , 2016, Pages 7-18

  Watterson, Daniel ^a   Modhiran, Naphak ^a   Young, Paul R ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Antiviral; Complement; Dengue; Flavivirus; Inhibitors

Indexed keywords

ANTIVIRUS AGENT; COMPLEMENT; DIMER; NONSTRUCTURAL PROTEIN 1; VIRUS PROTEIN; LIPID; NS1 PROTEIN, FLAVIVIRUS; PROTEIN BINDING; VIRAL PROTEIN;

CELL PROLIFERATION; DRUG POTENCY; DRUG TARGETING; EARLY INTERVENTION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; FLAVIVIRUS; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; REVIEW; VIRION; VIRUS ENTRY; VIRUS NUCLEOCAPSID; VIRUS REPLICATION; ANIMAL; CELL MEMBRANE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIPID METABOLISM; METABOLISM; MOLECULAR MODEL; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING; RNA PROCESSING;

ANIMALS; ANTIVIRAL AGENTS; CELL MEMBRANE; DRUG DESIGN; FLAVIVIRUS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; LIPID METABOLISM; LIPIDS; MODELS, MOLECULAR; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA PROCESSING, POST-TRANSCRIPTIONAL; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84962326951     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.02.014     Document Type: Review

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