Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

Science Translational Medicine

Volumn 7, Issue 304, 2015, Pages

  Beatty, P Robert ^a   Puerta Guardo, Henry ^a   Killingbeck, Sarah S ^a   Glasner, Dustin R ^a   Hopkins, Kaycie ^a   Harris, Eva ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DENGUE VACCINE; MONOCLONAL ANTIBODY; NONSTRUCTURAL PROTEIN 1; RECOMBINANT PROTEIN; ANTISERUM; AUTACOID; CYTOKINE; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DENGUE; DENGUE VIRUS 1; DENGUE VIRUS 2; DENGUE VIRUS 3; DENGUE VIRUS 4; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION PREVENTION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VACCINATION; VASCULAR DISEASE; VASCULAR LEAKAGE; ANIMAL; C57BL MOUSE; CYTOLOGY; DENGUE VIRUS; DRUG EFFECTS; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY; SYNDROME;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL MEMBRANE PERMEABILITY; CYTOKINES; DENGUE VIRUS; ENDOTHELIAL CELLS; HEK293 CELLS; HUMANS; IMMUNE SERA; INFLAMMATION MEDIATORS; LUNG; MICE, INBRED C57BL; SYNDROME; VACCINATION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84941254672     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa3787     Document Type: Article

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