Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1

Oncotarget

Volumn 7, Issue 3, 2016, Pages 2175-2188

  Wu, Bing ^a   Yu, Lu ^b   Wang, Yishi ^c   Wang, Hongtao ^a   Li, Chen ^c   Yin, Yue ^c   Yang, Jingrun ^c   Wang, Zhifa ^c   Zheng, Qiangsun ^a   Ma, Heng ^c  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Aging; ALDH2; Autophagy; Carbonyl stress; Gerotarget; SIRT1

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; PROTEIN P16; PROTEIN P53; RAB7 PROTEIN; SIRTUIN 1; TRANSCRIPTION FACTOR FKHR; 1,3 BENZODIOXOLE DERIVATIVE; ALDH2 PROTEIN, MOUSE; ATG7 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 7; BENZAMIDE DERIVATIVE; FOXO1 PROTEIN, MOUSE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; N-(1,3-BENZODIOXOL-5-YLMETHYL)-2,6-DICHLOROBENZAMIDE; RAB PROTEIN; SIRT1 PROTEIN, MOUSE;

AGING; ANIMAL CELL; ARTICLE; AUTOPHAGY; CARBONYLATION; CONTROLLED STUDY; DEACETYLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART EJECTION FRACTION; HEART FUNCTION; MALE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CARDIAC MUSCLE; CHEMISTRY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROTEIN CARBONYLATION; STARVATION;

AGING; ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 7; BENZAMIDES; BENZODIOXOLES; ENZYME ACTIVATION; FORKHEAD BOX PROTEIN O1; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MYOCARDIUM; PROTEIN CARBONYLATION; RAB GTP-BINDING PROTEINS; SIRTUIN 1; STARVATION;

EID: 84962222721     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6814     Document Type: Article

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