QKI deficiency promotes FoxO1 mediated nitrosative stress and endoplasmic reticulum stress contributing to increased vulnerability to ischemic injury in diabetic heart

Journal of Molecular and Cellular Cardiology

Volumn 75, Issue , 2014, Pages 131-140

  Guo, Wangang ^a   Jiang, Tiannan ^a   Lian, Cheng ^a   Wang, Haiyan ^a   Zheng, Qiangsun ^a   Ma, Heng ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Diabetes; FoxO1; Ischemia reperfusion injury; RNA binding protein QKI

Indexed keywords

3 NITROTYROSINE; CASPASE 3; CELL PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDUCIBLE NITRIC OXIDE SYNTHASE; INITIATION FACTOR 2ALPHA; LACTATE DEHYDROGENASE; NITRIC OXIDE; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; QUAKING 5 PROTEIN; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; MESSENGER RNA; QK PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPLASM; DIABETES MELLITUS; DISEASE PREDISPOSITION; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FOXO1 GENE; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMPAIRED GLUCOSE TOLERANCE; IN VIVO STUDY; INSULIN SENSITIVITY; MALE; MOUSE; NITROSATIVE STRESS; NONHUMAN; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; C57BL MOUSE; COMPLICATION; EXPERIMENTAL DIABETES MELLITUS; GENE SILENCING; GENETICS; HEART MUSCLE; HEART MUSCLE CELL; HUMAN; METABOLISM; MOUSE MUTANT; NITROSATION; PATHOLOGY; PROTEIN STABILITY;

ADENOVIRIDAE; ANIMALIA; MUS;

ANIMALS; APOPTOSIS; DIABETES MELLITUS, EXPERIMENTAL; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MICE, INBRED C57BL; MICE, OBESE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; NITROSATION; PROTEIN STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; UP-REGULATION;

EID: 84922809316     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.07.010     Document Type: Article

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