메뉴 건너뛰기




Volumn 61, Issue 6, 2015, Pages 2-8

ASPP and iASPP: Implication in cancer development and progression

Author keywords

Apoptosis; ASPP1; ASPP2; IASPP; P53

Indexed keywords

APOPTOSIS STIMULATING PROTEIN OF P53; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS STIMULATING PROTEIN OF P53; MICRORNA 124; PROTEIN BCL 2; PROTEIN P53; PROTEIN P63; PROTEIN P73; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN;

EID: 84962205018     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.14715/cmb/2015.61.6.2     Document Type: Article
Times cited : (39)

References (84)
  • 1
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • Vousden, K. H. and Lu, X., Live or let die: the cell's response to p53. Nat Rev Cancer 2002, 2: 594-604, doi:10.1038/nrc864
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 2
    • 24944476585 scopus 로고    scopus 로고
    • ASPP--Apoptotic specific regulator of p53
    • Liu, Z. J., Lu, X. and Zhong, S., ASPP--Apoptotic specific regulator of p53. Biochim. Biophys. Acta 2005, 1756: 77-80, doi:10.1016/j.bbcan.2005.08.002
    • (2005) Biochim. Biophys. Acta , vol.1756 , pp. 77-80
    • Liu, Z.J.1    Lu, X.2    Zhong, S.3
  • 3
    • 0037418624 scopus 로고    scopus 로고
    • The ASPP family: deciding between life and death after DNA damage
    • Slee, E. A. and Lu, X., The ASPP family: deciding between life and death after DNA damage. Toxicol. Lett. 2003, 139: 81-87
    • (2003) Toxicol. Lett. , vol.139 , pp. 81-87
    • Slee, E.A.1    Lu, X.2
  • 4
    • 33846551682 scopus 로고    scopus 로고
    • ASPP: a new family of oncogenes and tumour suppressor genes
    • Sullivan, A. and Lu, X., ASPP: a new family of oncogenes and tumour suppressor genes. Br. J. Cancer 2007, 96: 196-200, doi:10.1038/sj.bjc.6603525
    • (2007) Br. J. Cancer , vol.96 , pp. 196-200
    • Sullivan, A.1    Lu, X.2
  • 5
    • 33749610878 scopus 로고    scopus 로고
    • ASPP2: a gene that controls life and death in vivo
    • Vives, V., Slee, E. A. and Lu, X., ASPP2: a gene that controls life and death in vivo. Cell Cycle 2006, 5: 2187-2190
    • (2006) Cell Cycle , vol.5 , pp. 2187-2190
    • Vives, V.1    Slee, E.A.2    Lu, X.3
  • 8
    • 0029942921 scopus 로고    scopus 로고
    • The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M
    • Naumovski, L. and Cleary, M. L., The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M. Mol. Cell Biol. 1996, 16: 3884-3892
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3884-3892
    • Naumovski, L.1    Cleary, M.L.2
  • 9
    • 0033575818 scopus 로고    scopus 로고
    • NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2
    • Yang, J. P., Hori, M., Takahashi, N., Kawabe, T., Kato, H. and Okamoto, T., NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2. Oncogene 1999, 18: 5177-5186, doi:10.1038/sj.onc.1202904
    • (1999) Oncogene , vol.18 , pp. 5177-5186
    • Yang, J.P.1    Hori, M.2    Takahashi, N.3    Kawabe, T.4    Kato, H.5    Okamoto, T.6
  • 11
    • 10944228352 scopus 로고    scopus 로고
    • The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization
    • Slee, E. A., Gillotin, S., Bergamaschi, D., Royer, C., Llanos, S., Ali, S., Jin, B., Trigiante, G. and Lu, X., The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization. Oncogene 2004, 23: 9007-9016, doi:10.1038/sj.onc.1208088
    • (2004) Oncogene , vol.23 , pp. 9007-9016
    • Slee, E.A.1    Gillotin, S.2    Bergamaschi, D.3    Royer, C.4    Llanos, S.5    Ali, S.6    Jin, B.7    Trigiante, G.8    Lu, X.9
  • 12
    • 34247143604 scopus 로고    scopus 로고
    • Identification of a novel isoform of iASPP and its interaction with p53
    • Zhang, X., Diao, S., Rao, Q., Xing, H., Liu, H., Liao, X., Wang, M. and Wang, J., Identification of a novel isoform of iASPP and its interaction with p53. J. Mol. Biol. 2007, 368: 1162-1171, doi:10.1016/j.jmb.2007.03.001
    • (2007) J. Mol. Biol. , vol.368 , pp. 1162-1171
    • Zhang, X.1    Diao, S.2    Rao, Q.3    Xing, H.4    Liu, H.5    Liao, X.6    Wang, M.7    Wang, J.8
  • 14
    • 33644555840 scopus 로고    scopus 로고
    • ASPP [corrected] and cancer
    • Trigiante, G. and Lu, X., ASPP [corrected] and cancer. Nat. Rev. Cancer 2006, 6: 217-226, doi:10.1038/nrc1818
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 217-226
    • Trigiante, G.1    Lu, X.2
  • 16
    • 27244438584 scopus 로고    scopus 로고
    • Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis
    • Roman-Gomez, J., Jimenez-Velasco, A., Agirre, X., Prosper, F., Heiniger, A. and Torres, A., Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis. J. Clin. Oncol. 2005, 23: 7043-7049, doi:10.1200/JCO.2005.01.4944
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7043-7049
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3    Prosper, F.4    Heiniger, A.5    Torres, A.6
  • 17
    • 14844321860 scopus 로고    scopus 로고
    • Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53
    • Liu, Z. J., Lu, X., Zhang, Y., Zhong, S., Gu, S. Z., Zhang, X. B., Yang, X. and Xin, H. M., Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53. FEBS Lett. 2005, 579: 1587-1590, doi:10.1016/j.febslet.2005.01.069
    • (2005) FEBS Lett. , vol.579 , pp. 1587-1590
    • Liu, Z.J.1    Lu, X.2    Zhang, Y.3    Zhong, S.4    Gu, S.Z.5    Zhang, X.B.6    Yang, X.7    Xin, H.M.8
  • 18
    • 73449083762 scopus 로고    scopus 로고
    • Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma
    • Zhao, J., Wu, G., Bu, F., Lu, B., Liang, A., Cao, L., Tong, X., Lu, X., Wu, M. and Guo, Y., Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma. Hepatology 2010, 51: 142-153, doi:10.1002/hep.23247
    • (2010) Hepatology , vol.51 , pp. 142-153
    • Zhao, J.1    Wu, G.2    Bu, F.3    Lu, B.4    Liang, A.5    Cao, L.6    Tong, X.7    Lu, X.8    Wu, M.9    Guo, Y.10
  • 19
    • 17144418954 scopus 로고    scopus 로고
    • Apoptosis-stimulating protein of p53-2 (ASPP2/53BP2L) is an E2F target gene
    • Chen, D., Padiernos, E., Ding, F., Lossos, I. S. and Lopez, C. D., Apoptosis-stimulating protein of p53-2 (ASPP2/53BP2L) is an E2F target gene. Cell Death. Differ. 2005, 12: 358-368, doi:10.1038/sj.cdd.4401536
    • (2005) Cell Death. Differ. , vol.12 , pp. 358-368
    • Chen, D.1    Padiernos, E.2    Ding, F.3    Lossos, I.S.4    Lopez, C.D.5
  • 21
    • 17144371342 scopus 로고    scopus 로고
    • Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F
    • Hershko, T., Chaussepied, M., Oren, M. and Ginsberg, D., Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F. Cell Death. Differ. 2005, 12: 377-383, doi:10.1038/sj.cdd.4401575
    • (2005) Cell Death. Differ. , vol.12 , pp. 377-383
    • Hershko, T.1    Chaussepied, M.2    Oren, M.3    Ginsberg, D.4
  • 23
    • 19144367014 scopus 로고    scopus 로고
    • Selection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA library
    • Li, Z., Stanelle, J., Leurs, C., Hanenberg, H. and Putzer, B. M., Selection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA library. Nucleic Acids Res. 2005, 33: 2813-2821, doi:10.1093/nar/gki581
    • (2005) Nucleic Acids Res. , vol.33 , pp. 2813-2821
    • Li, Z.1    Stanelle, J.2    Leurs, C.3    Hanenberg, H.4    Putzer, B.M.5
  • 24
    • 27144456615 scopus 로고    scopus 로고
    • Control of ASPP2/(53BP2L) protein levels by proteasomal degradation modulates p53 apoptotic function
    • Zhu, Z., Ramos, J., Kampa, K., Adimoolam, S., Sirisawad, M., Yu, Z., Chen, D., Naumovski, L. and Lopez, C. D., Control of ASPP2/(53BP2L) protein levels by proteasomal degradation modulates p53 apoptotic function. J. Biol. Chem. 2005, 280: 34473-34480, doi:10.1074/jbc.M503736200
    • (2005) J. Biol. Chem. , vol.280 , pp. 34473-34480
    • Zhu, Z.1    Ramos, J.2    Kampa, K.3    Adimoolam, S.4    Sirisawad, M.5    Yu, Z.6    Chen, D.7    Naumovski, L.8    Lopez, C.D.9
  • 25
    • 0030575866 scopus 로고    scopus 로고
    • Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2
    • Gorina, S. and Pavletich, N. P., Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science 1996, 274: 1001-1005
    • (1996) Science , vol.274 , pp. 1001-1005
    • Gorina, S.1    Pavletich, N.P.2
  • 28
    • 23844528539 scopus 로고    scopus 로고
    • Inhibition of the 53BP2S-mediated apoptosis by nuclear factor kappaB and Bcl-2 family proteins
    • Takahashi, N., Kobayashi, S., Kajino, S., Imai, K., Tomoda, K., Shimizu, S. and Okamoto, T., Inhibition of the 53BP2S-mediated apoptosis by nuclear factor kappaB and Bcl-2 family proteins. Genes Cells 2005, 10: 803-811, doi:10.1111/j.1365-2443.2005.00878.x
    • (2005) Genes Cells , vol.10 , pp. 803-811
    • Takahashi, N.1    Kobayashi, S.2    Kajino, S.3    Imai, K.4    Tomoda, K.5    Shimizu, S.6    Okamoto, T.7
  • 29
    • 84924054377 scopus 로고    scopus 로고
    • The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly
    • Zhang, Y., Wang, Y., Wei, Y., Ma, J., Peng, J., Wumaier, R., Shen, S., Zhang, P. and Yu, L., The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly. Biochem. Biophys. Res. Commun. 2015, 458: 494-500, doi:10.1016/j.bbrc.2015.01.136
    • (2015) Biochem. Biophys. Res. Commun. , vol.458 , pp. 494-500
    • Zhang, Y.1    Wang, Y.2    Wei, Y.3    Ma, J.4    Peng, J.5    Wumaier, R.6    Shen, S.7    Zhang, P.8    Yu, L.9
  • 30
    • 84891399680 scopus 로고    scopus 로고
    • Phosphorylation of ASPP2 by RAS/MAPK pathway is critical for its full pro-apoptotic function
    • Godin-Heymann, N., Wang, Y., Slee, E. and Lu, X., Phosphorylation of ASPP2 by RAS/MAPK pathway is critical for its full pro-apoptotic function. PLoS. One. 2013, 8: e82022, doi:10.1371/journal.pone.0082022
    • (2013) PLoS. One. , vol.8 , pp. e82022
    • Godin-Heymann, N.1    Wang, Y.2    Slee, E.3    Lu, X.4
  • 31
    • 84874949078 scopus 로고    scopus 로고
    • ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells
    • Wang, Y., Godin-Heymann, N., Dan, W., X, Bergamaschi, D., Llanos, S. and Lu, X., ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells. Cell Death. Differ. 2013, 20: 525-534, doi:10.1038/cdd.2013.3
    • (2013) Cell Death. Differ. , vol.20 , pp. 525-534
    • Wang, Y.1    Godin-Heymann, N.2    Dan, W.X.3    Bergamaschi, D.4    Llanos, S.5    Lu, X.6
  • 32
    • 84879862491 scopus 로고    scopus 로고
    • Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2)
    • Janke, K., Brockmeier, U., Kuhlmann, K., Eisenacher, M., Nolde, J., Meyer, H. E., Mairbaurl, H. and Metzen, E., Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2). J. Cell Sci. 2013, 126: 2629-2640, doi:10.1242/jcs.117564
    • (2013) J. Cell Sci. , vol.126 , pp. 2629-2640
    • Janke, K.1    Brockmeier, U.2    Kuhlmann, K.3    Eisenacher, M.4    Nolde, J.5    Meyer, H.E.6    Mairbaurl, H.7    Metzen, E.8
  • 34
    • 83355166956 scopus 로고    scopus 로고
    • Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif
    • Llanos, S., Royer, C., Lu, M., Bergamaschi, D., Lee, W. H. and Lu, X., Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif. J. Biol. Chem. 2011, 286: 43039-43044, doi:10.1074/jbc.M111.270751
    • (2011) J. Biol. Chem. , vol.286 , pp. 43039-43044
    • Llanos, S.1    Royer, C.2    Lu, M.3    Bergamaschi, D.4    Lee, W.H.5    Lu, X.6
  • 35
    • 79958115100 scopus 로고    scopus 로고
    • The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53
    • Gillotin, S. and Lu, X., The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53. FEBS Lett. 2011, 585: 1778-1782, doi:10.1016/j.febslet.2011.04.012
    • (2011) FEBS Lett. , vol.585 , pp. 1778-1782
    • Gillotin, S.1    Lu, X.2
  • 36
    • 52649151797 scopus 로고    scopus 로고
    • Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax
    • Patel, S., George, R., Autore, F., Fraternali, F., Ladbury, J. E. and Nikolova, P. V., Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax. Nucleic Acids Res. 2008, 36: 5139-5151, doi:10.1093/nar/gkn490
    • (2008) Nucleic Acids Res. , vol.36 , pp. 5139-5151
    • Patel, S.1    George, R.2    Autore, F.3    Fraternali, F.4    Ladbury, J.E.5    Nikolova, P.V.6
  • 37
    • 38949123716 scopus 로고    scopus 로고
    • Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73
    • Robinson, R. A., Lu, X., Jones, E. Y. and Siebold, C., Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure. 2008, 16: 259-268, doi:10.1016/j.str.2007.11.012
    • (2008) Structure. , vol.16 , pp. 259-268
    • Robinson, R.A.1    Lu, X.2    Jones, E.Y.3    Siebold, C.4
  • 38
    • 67649405072 scopus 로고    scopus 로고
    • Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins
    • Ahn, J., Byeon, I. J., Byeon, C. H. and Gronenborn, A. M., Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins. J. Biol. Chem. 2009, 284: 13812-13822, doi:10.1074/jbc.M808821200
    • (2009) J. Biol. Chem. , vol.284 , pp. 13812-13822
    • Ahn, J.1    Byeon, I.J.2    Byeon, C.H.3    Gronenborn, A.M.4
  • 39
    • 34948830225 scopus 로고    scopus 로고
    • The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP
    • Mantovani, F., Tocco, F., Girardini, J., Smith, P., Gasco, M., Lu, X., Crook, T. and Del, S. G., The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP. Nat. Struct. Mol. Biol. 2007, 14: 912-920, doi:10.1038/nsmb1306
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 912-920
    • Mantovani, F.1    Tocco, F.2    Girardini, J.3    Smith, P.4    Gasco, M.5    Lu, X.6    Crook, T.7    Del, S.G.8
  • 40
    • 78049450251 scopus 로고    scopus 로고
    • Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP
    • Vigneron, A. M., Ludwig, R. L. and Vousden, K. H., Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP. Genes Dev. 2010, 24: 2430-2439, doi:10.1101/gad.1954310
    • (2010) Genes Dev. , vol.24 , pp. 2430-2439
    • Vigneron, A.M.1    Ludwig, R.L.2    Vousden, K.H.3
  • 41
    • 10644232879 scopus 로고    scopus 로고
    • Abnormal mRNA expression of ASPP members in leukemia cell lines
    • Liu, Z. J., Zhang, Y., Zhang, X. B. and Yang, X., Abnormal mRNA expression of ASPP members in leukemia cell lines. Leukemia 2004, 18: 880, doi:10.1038/sj.leu.2403300
    • (2004) Leukemia , vol.18 , pp. 880
    • Liu, Z.J.1    Zhang, Y.2    Zhang, X.B.3    Yang, X.4
  • 42
    • 84887006964 scopus 로고    scopus 로고
    • Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation
    • Mak, V. C., Lee, L., Siu, M. K., Wong, O. G., Lu, X., Ngan, H. Y., Wong, E. S. and Cheung, A. N., Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation. Carcinogenesis 2013, 34: 2170-2177, doi:10.1093/carcin/bgt161
    • (2013) Carcinogenesis , vol.34 , pp. 2170-2177
    • Mak, V.C.1    Lee, L.2    Siu, M.K.3    Wong, O.G.4    Lu, X.5    Ngan, H.Y.6    Wong, E.S.7    Cheung, A.N.8
  • 43
    • 10644278820 scopus 로고    scopus 로고
    • The expression of iASPP in acute leukemias
    • Zhang, X., Wang, M., Zhou, C., Chen, S. and Wang, J., The expression of iASPP in acute leukemias. Leuk. Res. 2005, 29: 179-183, doi:10.1016/j.leukres.2004.07.001
    • (2005) Leuk. Res. , vol.29 , pp. 179-183
    • Zhang, X.1    Wang, M.2    Zhou, C.3    Chen, S.4    Wang, J.5
  • 44
    • 84903716185 scopus 로고    scopus 로고
    • Oncogene iASPP enhances self-renewal of hematopoietic stem cells and facilitates their resistance to chemotherapy and irradiation
    • Jia, Y., Peng, L., Rao, Q., Xing, H., Huai, L., Yu, P., Chen, Y., Wang, C., Wang, M., Mi, Y. and Wang, J., Oncogene iASPP enhances self-renewal of hematopoietic stem cells and facilitates their resistance to chemotherapy and irradiation. FASEB J. 2014, 28: 2816-2827, doi:10.1096/fj.13-244632
    • (2014) FASEB J. , vol.28 , pp. 2816-2827
    • Jia, Y.1    Peng, L.2    Rao, Q.3    Xing, H.4    Huai, L.5    Yu, P.6    Chen, Y.7    Wang, C.8    Wang, M.9    Mi, Y.10    Wang, J.11
  • 45
    • 84861556609 scopus 로고    scopus 로고
    • Abnormal expression pattern of the ASPP family of proteins in human non-small cell lung cancer and regulatory functions on apoptosis through p53 by iASPP
    • Li, S., Shi, G., Yuan, H., Zhou, T., Zhang, Q., Zhu, H. and Wang, X., Abnormal expression pattern of the ASPP family of proteins in human non-small cell lung cancer and regulatory functions on apoptosis through p53 by iASPP. Oncol. Rep. 2012, 28: 133-140, doi:10.3892/or.2012.1778
    • (2012) Oncol. Rep. , vol.28 , pp. 133-140
    • Li, S.1    Shi, G.2    Yuan, H.3    Zhou, T.4    Zhang, Q.5    Zhu, H.6    Wang, X.7
  • 46
    • 78650609032 scopus 로고    scopus 로고
    • iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway
    • Chen, J., Xie, F., Zhang, L. and Jiang, W. G., iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway. BMC. Cancer 2010, 10: 694, doi:10.1186/1471-2407-10-694
    • (2010) BMC. Cancer , vol.10 , pp. 694
    • Chen, J.1    Xie, F.2    Zhang, L.3    Jiang, W.G.4
  • 47
    • 80054746852 scopus 로고    scopus 로고
    • Inhibitory member of the apoptosis-stimulating protein of p53 (ASPP) family promotes growth and tumorigenesis in human p53-deficient prostate cancer cells
    • Zhang, B., Xiao, H. J., Chen, J., Tao, X. and Cai, L. H., Inhibitory member of the apoptosis-stimulating protein of p53 (ASPP) family promotes growth and tumorigenesis in human p53-deficient prostate cancer cells. Prostate Cancer Prostatic. Dis. 2011, 14: 219-224, doi:10.1038/pcan.2011.25
    • (2011) Prostate Cancer Prostatic. Dis. , vol.14 , pp. 219-224
    • Zhang, B.1    Xiao, H.J.2    Chen, J.3    Tao, X.4    Cai, L.H.5
  • 49
    • 85015479175 scopus 로고    scopus 로고
    • Downregulation of inhibitor of apoptosisstimulating protein of p53 inhibits proliferation and promotes apoptosis of gastric cancer cells
    • Wang, L. L., Xu, Z., Peng, Y., Li, L. C. and Wu, X. L., Downregulation of inhibitor of apoptosisstimulating protein of p53 inhibits proliferation and promotes apoptosis of gastric cancer cells. Mol. Med. Rep. 2015, doi:10.3892/mmr.2015.3587
    • (2015) Mol. Med. Rep.
    • Wang, L.L.1    Xu, Z.2    Peng, Y.3    Li, L.C.4    Wu, X.L.5
  • 50
    • 79961118984 scopus 로고    scopus 로고
    • Down-regulation of iASPP in human hepatocellular carcinoma cells inhibits cell proliferation and tumor growth
    • Lin, B. L., Xie, D. Y., Xie, S. B., Xie, J. Q., Zhang, X. H., Zhang, Y. F. and Gao, Z. L., Down-regulation of iASPP in human hepatocellular carcinoma cells inhibits cell proliferation and tumor growth. Neoplasma 2011, 58: 205-210
    • (2011) Neoplasma , vol.58 , pp. 205-210
    • Lin, B.L.1    Xie, D.Y.2    Xie, S.B.3    Xie, J.Q.4    Zhang, X.H.5    Zhang, Y.F.6    Gao, Z.L.7
  • 52
    • 84940181326 scopus 로고    scopus 로고
    • In vitro effect of iASPP on cell growth of oral tongue squamous cell carcinoma
    • Chen, Y., Yan, W., He, S., Chen, J., Chen, D., Zhang, Z., Liu, Z., Ding, X. and Wang, A., In vitro effect of iASPP on cell growth of oral tongue squamous cell carcinoma. Chin J. Cancer Res. 2014, 26: 382-390, doi:10.3978/j.issn.1000-9604.2014.07.05
    • (2014) Chin J. Cancer Res. , vol.26 , pp. 382-390
    • Chen, Y.1    Yan, W.2    He, S.3    Chen, J.4    Chen, D.5    Zhang, Z.6    Liu, Z.7    Ding, X.8    Wang, A.9
  • 53
    • 84921065292 scopus 로고    scopus 로고
    • Cytoplasmic iASPP expression as a novel prognostic indicator in oral cavity squamous cell carcinoma
    • Kim, J. W., Roh, J. L., Park, Y., Cho, K. J., Choi, S. H., Nam, S. Y. and Kim, S. Y., Cytoplasmic iASPP expression as a novel prognostic indicator in oral cavity squamous cell carcinoma. Ann. Surg. Oncol. 2015, 22: 662-669, doi:10.1245/s10434-014-4003-0
    • (2015) Ann. Surg. Oncol. , vol.22 , pp. 662-669
    • Kim, J.W.1    Roh, J.L.2    Park, Y.3    Cho, K.J.4    Choi, S.H.5    Nam, S.Y.6    Kim, S.Y.7
  • 54
    • 84880569770 scopus 로고    scopus 로고
    • Elevated expression of iASPP correlates with poor prognosis and chemoresistance/radioresistance in FIGO Ib1-IIa squamous cell cervical cancer
    • Cao, L., Huang, Q., He, J., Lu, J. and Xiong, Y., Elevated expression of iASPP correlates with poor prognosis and chemoresistance/radioresistance in FIGO Ib1-IIa squamous cell cervical cancer. Cell Tissue Res. 2013, 352: 361-369, doi:10.1007/s00441-013-1569-y
    • (2013) Cell Tissue Res. , vol.352 , pp. 361-369
    • Cao, L.1    Huang, Q.2    He, J.3    Lu, J.4    Xiong, Y.5
  • 55
    • 84880334438 scopus 로고    scopus 로고
    • Elevated expression of iASPP in head and neck squamous cell carcinoma and its clinical significance
    • Liu, Z., Zhang, X., Huang, D., Liu, Y., Zhang, X., Liu, L., Li, G., Dai, Y., Tan, H., Xiao, J. and Tian, Y., Elevated expression of iASPP in head and neck squamous cell carcinoma and its clinical significance. Med. Oncol. 2012, 29: 3381-3388, doi:10.1007/s12032-012-0306-9
    • (2012) Med. Oncol. , vol.29 , pp. 3381-3388
    • Liu, Z.1    Zhang, X.2    Huang, D.3    Liu, Y.4    Zhang, X.5    Liu, L.6    Li, G.7    Dai, Y.8    Tan, H.9    Xiao, J.10    Tian, Y.11
  • 57
    • 78649698576 scopus 로고    scopus 로고
    • Increased expression of iASPP, regulated by hepatitis B virus X protein-mediated NF-kappaB activation, in hepatocellular carcinoma
    • Lu, B., Guo, H., Zhao, J., Wang, C., Wu, G., Pang, M., Tong, X., Bu, F., Liang, A., Hou, S., Fan, X., Dai, J., Wang, H. and Guo, Y., Increased expression of iASPP, regulated by hepatitis B virus X protein-mediated NF-kappaB activation, in hepatocellular carcinoma. Gastroenterology 2010, 139: 2183-2194, doi:10.1053/j.gastro.2010.06.049
    • (2010) Gastroenterology , vol.139 , pp. 2183-2194
    • Lu, B.1    Guo, H.2    Zhao, J.3    Wang, C.4    Wu, G.5    Pang, M.6    Tong, X.7    Bu, F.8    Liang, A.9    Hou, S.10    Fan, X.11    Dai, J.12    Wang, H.13    Guo, Y.14
  • 59
    • 0033970863 scopus 로고    scopus 로고
    • Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines
    • Mori, T., Okamoto, H., Takahashi, N., Ueda, R. and Okamoto, T., Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines. FEBS Lett. 2000, 465: 124-128, doi:S0014-5793(99)01726-3
    • (2000) FEBS Lett. , vol.465 , pp. 124-128
    • Mori, T.1    Okamoto, H.2    Takahashi, N.3    Ueda, R.4    Okamoto, T.5
  • 62
    • 48549088301 scopus 로고    scopus 로고
    • iASPP inhibition: increased options in targeting the p53 family for cancer therapy
    • Bell, H. S. and Ryan, K. M., iASPP inhibition: increased options in targeting the p53 family for cancer therapy. Cancer Res. 2008, 68: 4959-4962, doi:10.1158/0008-5472.CAN-08-0182
    • (2008) Cancer Res. , vol.68 , pp. 4959-4962
    • Bell, H.S.1    Ryan, K.M.2
  • 63
    • 84919495724 scopus 로고    scopus 로고
    • A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53
    • Qiu, S., Cai, Y., Gao, X., Gu, S. Z. and Liu, Z. J., A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53. Cancer Lett. 2015, 356: 910-917, doi:10.1016/j.canlet.2014.10.044
    • (2015) Cancer Lett. , vol.356 , pp. 910-917
    • Qiu, S.1    Cai, Y.2    Gao, X.3    Gu, S.Z.4    Liu, Z.J.5
  • 64
    • 57049137197 scopus 로고    scopus 로고
    • Effect of RNA interference of iASPP on the apoptosis in MCF-7 breast cancer cells
    • Liu, Z. J., Cai, Y., Hou, L., Gao, X., Xin, H. M., Lu, X., Zhong, S., Gu, S. Z. and Chen, J., Effect of RNA interference of iASPP on the apoptosis in MCF-7 breast cancer cells. Cancer Invest 2008, 26: 878-882, doi:10.1080/07357900801965042
    • (2008) Cancer Invest , vol.26 , pp. 878-882
    • Liu, Z.J.1    Cai, Y.2    Hou, L.3    Gao, X.4    Xin, H.M.5    Lu, X.6    Zhong, S.7    Gu, S.Z.8    Chen, J.9
  • 65
    • 67649264588 scopus 로고    scopus 로고
    • siRNA-mediated down-regulation of iASPP promotes apoptosis induced by etoposide and daunorubicin in leukemia cells expressing wild-type p53
    • Liu, H., Wang, M., Diao, S., Rao, Q., Zhang, X., Xing, H. and Wang, J., siRNA-mediated down-regulation of iASPP promotes apoptosis induced by etoposide and daunorubicin in leukemia cells expressing wild-type p53. Leuk. Res. 2009, 33: 1243-1248, doi:10.1016/j.leukres.2009.02.016
    • (2009) Leuk. Res. , vol.33 , pp. 1243-1248
    • Liu, H.1    Wang, M.2    Diao, S.3    Rao, Q.4    Zhang, X.5    Xing, H.6    Wang, J.7
  • 67
    • 84877276570 scopus 로고    scopus 로고
    • MicroRNA-124 regulates the proliferation of colorectal cancer cells by targeting iASPP
    • Liu, K., Zhao, H., Yao, H., Lei, S., Lei, Z., Li, T. and Qi, H., MicroRNA-124 regulates the proliferation of colorectal cancer cells by targeting iASPP. Biomed. Res. Int. 2013, 2013: 867537, doi:10.1155/2013/867537
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 867537
    • Liu, K.1    Zhao, H.2    Yao, H.3    Lei, S.4    Lei, Z.5    Li, T.6    Qi, H.7
  • 68
    • 84878214332 scopus 로고    scopus 로고
    • Downregulation of miR-124 promotes the growth and invasiveness of glioblastoma cells involving upregulation of PPP1R13L
    • Zhao, W. H., Wu, S. Q. and Zhang, Y. D., Downregulation of miR-124 promotes the growth and invasiveness of glioblastoma cells involving upregulation of PPP1R13L. Int. J. Mol. Med. 2013, 32: 101-107, doi:10.3892/ijmm.2013.1365
    • (2013) Int. J. Mol. Med. , vol.32 , pp. 101-107
    • Zhao, W.H.1    Wu, S.Q.2    Zhang, Y.D.3
  • 69
    • 84879912122 scopus 로고    scopus 로고
    • MicroRNA-124-mediated regulation of inhibitory member of apoptosis-stimulating protein of p53 family in experimental stroke
    • Liu, X., Li, F., Zhao, S., Luo, Y., Kang, J., Zhao, H., Yan, F., Li, S. and Ji, X., MicroRNA-124-mediated regulation of inhibitory member of apoptosis-stimulating protein of p53 family in experimental stroke. Stroke 2013, 44: 1973-1980, doi:10.1161/STROKEAHA.111.000613
    • (2013) Stroke , vol.44 , pp. 1973-1980
    • Liu, X.1    Li, F.2    Zhao, S.3    Luo, Y.4    Kang, J.5    Zhao, H.6    Yan, F.7    Li, S.8    Ji, X.9
  • 70
    • 11144315535 scopus 로고    scopus 로고
    • Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
    • Issaeva, N., Bozko, P., Enge, M., Protopopova, M., Verhoef, L. G., Masucci, M., Pramanik, A. and Selivanova, G., Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nat. Med. 2004, 10: 1321-1328, doi:10.1038/nm1146
    • (2004) Nat. Med. , vol.10 , pp. 1321-1328
    • Issaeva, N.1    Bozko, P.2    Enge, M.3    Protopopova, M.4    Verhoef, L.G.5    Masucci, M.6    Pramanik, A.7    Selivanova, G.8
  • 71
    • 84879588683 scopus 로고    scopus 로고
    • Simvastatin induces caspase-dependent apoptosis and activates P53 in OCM-1 cells
    • Wang, Y., Xu, S. L., Wu, Y. Z., Zhao, M. S., Xu, W. J., Yang, H. Y. and Li, Y. X., Simvastatin induces caspase-dependent apoptosis and activates P53 in OCM-1 cells. Exp. Eye Res. 2013, 113: 128-134, doi:10.1016/j.exer.2013.05.013
    • (2013) Exp. Eye Res. , vol.113 , pp. 128-134
    • Wang, Y.1    Xu, S.L.2    Wu, Y.Z.3    Zhao, M.S.4    Xu, W.J.5    Yang, H.Y.6    Li, Y.X.7
  • 72
    • 79954561033 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1
    • Shi, Y., Yang, S., Troup, S., Lu, X., Callaghan, S., Park, D. S., Xing, Y. and Yang, X., Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1. Oncol. Rep. 2011, 25: 1713-1719, doi:10.3892/or.2011.1248
    • (2011) Oncol. Rep. , vol.25 , pp. 1713-1719
    • Shi, Y.1    Yang, S.2    Troup, S.3    Lu, X.4    Callaghan, S.5    Park, D.S.6    Xing, Y.7    Yang, X.8
  • 73
    • 84962175330 scopus 로고    scopus 로고
    • Association of NOTCH with different microRNAs in head and neck cancer
    • Masood, N., Qureshi, M. Z. and Yasmin, A., Association of NOTCH with different microRNAs in head and neck cancer. Cell. Mol. Biol. 2015, 61(6): 9-16.
    • (2015) Cell. Mol. Biol. , vol.61 , Issue.6 , pp. 9-16
    • Masood, N.1    Qureshi, M.Z.2    Yasmin, A.3
  • 75
    • 84962167853 scopus 로고    scopus 로고
    • The Notch signaling pathway in esophageal adenocarcinoma
    • Wang, Z., Chen, J. and Capobianco, A. J., The Notch signaling pathway in esophageal adenocarcinoma. Cell. Mol. Biol. 201561, (6): 24-32.
    • (2015) Cell. Mol. Biol. , vol.61 , Issue.6 , pp. 24-32
    • Wang, Z.1    Chen, J.2    Capobianco, A.J.3
  • 76
    • 84962191062 scopus 로고    scopus 로고
    • TRAIL and targeting cancer cells: between promises and obstacles
    • Limami, Y., Pinon, A., Riaz, A. and Simon, A., TRAIL and targeting cancer cells: between promises and obstacles. Cell. Mol. Biol. 201561, (6): 33-38.
    • (2015) Cell. Mol. Biol. , vol.61 , Issue.6 , pp. 33-38
    • Limami, Y.1    Pinon, A.2    Riaz, A.3    Simon, A.4
  • 81
  • 82
    • 84962141567 scopus 로고    scopus 로고
    • Hesperetin exerts apoptotic effect on A431 skin carcinoma cells by regulating mitogen activated protein kinases and cyclins
    • Smina, T. P., Mohan, A., Ayyappa, K. A., Sethuraman, S. and Krishnan, U. M., Hesperetin exerts apoptotic effect on A431 skin carcinoma cells by regulating mitogen activated protein kinases and cyclins. Cell. Mol. Biol. 2015, 61(6): 92-99.
    • (2015) Cell. Mol. Biol. , vol.61 , Issue.6 , pp. 92-99
    • Smina, T.P.1    Mohan, A.2    Ayyappa, K.A.3    Sethuraman, S.4    Krishnan, U.M.5
  • 83
    • 84962168850 scopus 로고    scopus 로고
    • Indirect role of microRNAs and transcription factors in the regulation of important cancer genes: A network biology approach
    • Ahmadi, M., Jafari, R., Marashi, S. A. and Farazmand, A., Indirect role of microRNAs and transcription factors in the regulation of important cancer genes: A network biology approach. Cell. Mol. Biol. 2015, 61(6): 100-107.
    • (2015) Cell. Mol. Biol. , vol.61 , Issue.6 , pp. 100-107
    • Ahmadi, M.1    Jafari, R.2    Marashi, S.A.3    Farazmand, A.4
  • 84
    • 84962165962 scopus 로고    scopus 로고
    • Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population
    • Zahoor, A., Mansoor, Q., Farooqi, A. A., Fayyaz, S., Naz, G. and Ismail, M., Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population. Cell. Mol. Biol. 2015, 61(6): 108-112.
    • (2015) Cell. Mol. Biol. , vol.61 , Issue.6 , pp. 108-112
    • Zahoor, A.1    Mansoor, Q.2    Farooqi, A.A.3    Fayyaz, S.4    Naz, G.5    Ismail, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.