A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53

Cancer Letters

Volumn 356, Issue 2, 2015, Pages 910-917

  Qiu, Shi ^a   Cai, Yun ^a   Gao, Xing ^a   Gu, Shou Zhi ^a,b   Liu, Ze Jun ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b SEIREI CHRISTOPHER UNIVERSITY   (Japan)

Author keywords

A34; Apoptosis; Derepress; IASPP; P53

Indexed keywords

MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN A34; PROTEIN BAX; PROTEIN IASPP; PROTEIN P53; PUMA PROTEIN; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT; PPP1R13L PROTEIN, HUMAN; REPRESSOR PROTEIN; SIGNAL PEPTIDE; TP53 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; ANIMAL; BONE TUMOR; CHROMATIN IMMUNOPRECIPITATION; DRUG SCREENING; FLOW CYTOMETRY; GENETICS; IMMUNOPRECIPITATION; METABOLISM; MOUSE; NUDE MOUSE; OSTEOSARCOMA; PATHOLOGY; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BONE NEOPLASMS; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, NUDE; OSTEOSARCOMA; PEPTIDE FRAGMENTS; REPRESSOR PROTEINS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84919495724     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.10.044     Document Type: Article

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