MicroRNA124 regulate cell growth of prostate cancer cells by targeting iASPP

International Journal of Clinical and Experimental Pathology

Volumn 7, Issue 5, 2014, Pages 2283-2290

  Chen, Jun ^a,b   Xiao, Hengjun ^b   Huang, Zhansen ^b   Hu, Zhiming ^b   Qi, Tao ^b   Zhang, Bin ^b   Tao, Xin ^b   Liu, Song Hao ^a  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cell growth; IASPP; Mir124; Prostate cancer

Indexed keywords

3' UNTRANSLATED REGION; MESSENGER RNA; MICRORNA; MIRN124 MICRORNA, HUMAN; PPP1R13L PROTEIN, HUMAN; REPRESSOR PROTEIN; SIGNAL PEPTIDE; SMALL INTERFERING RNA;

3' UNTRANSLATED REGION; BINDING SITE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HUMAN; LENTIVIRINAE; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; REPORTER GENE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; GENETIC VECTORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LENTIVIRUS; MALE; MICRORNAS; PROSTATIC NEOPLASMS; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84902477302     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Debes JD, Tindall DJ. Mechanisms of androgen- refractory prostate cancer. N Engl J Med 2004; 351: 1488-1490.
2. Schroder FH. Progress in understanding androgen- independent prostate cancer (AIPC): a review of potential endocrine-mediated mechanisms. Eur Urol 2008; 53: 1129-1137.
3. Zhang B, Xiao HJ, Chen J, Tao X, Cai LH. Inhibitory member of the apoptosis-stimulating protein of p53 (ASPP) family promotes growth and tumorigenesis in human p53-deficient prostate cancer cells. Prostate Cancer Prostatic Dis 2011; 14: 219-224.
4. Rana TM. Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol 2007; 8: 23-36.
5. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
6. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003; 115: 787-798.
7. Krek A, Grun D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, Stoffel M, Rajewsky N. Combinatorial microRNA target predictions. Nat Genet 2005; 37: 495-500.
8. Nielsen CB, Shomron N, Sandberg R, Hornstein E, Kitzman J, Burge CB. Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. RNA 2007; 13: 1894-1910.
9. Lee Y, Jeon K, Lee JT, Kim S, Kim VN. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J 2002; 21: 4663-4670.
10. Liu ZJ, Zhang Y, Zhang XB, Yang X. Abnormal mRNA expression of ASPP members in leukemia cell lines. Leukemia 2004; 18: 880.
11. Lossos IS, Natkunam Y, Levy R, Lopez CD. Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome. Leuk Lymphoma 2002; 43: 2309-2317.
12. Liu ZJ, Cai Y, Hou L, Gao X, Xin HM, Lu X, Zhong S, Gu SZ, Chen J. Effect of RNA interference of iASPP on the Apoptosis in MCF-7 breast cancer cells. Cancer Invest 2008; 26: 878-882.
13. Agirre X, Román-Gómez J, Jimenez-Velasco A, Garate L, Montiel-Duarte C, Navarro G, Vazquez I, Zalacain M, Calasanz MJ, Heiniger A, Torres A, Minna JD, Prósper F. ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia. Oncogene 2006; 25: 1862-1870.
14. Zhang X, Wang M, Zhou C, Chen S, Wang J. The expression of iASPP in acute leukemias. Leuk Res 2005; 29: 179-183.
15. Chen J, Xie F, Zhang L, Jiang WG. iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway. BMC Cancer 2010; 10: 694.
16. Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML. iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human. Nat Genet 2003; 33: 162-167.
17. Yang JP, Hori M, Sanda T, Okamoto T. Identification of a novel inhibitor of nuclear factor-κB, RelA-associated inhibitor. J Biol Chem 1999; 274: 15662-15670.
18. Takada N, Sanda T, Okamoto H, Yang JP, Asamitsu K, Sarol L, Kimura G, Uranishi H, Tetsuka T, Okamoto T. RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and Sp1 actions. J Virol 2002; 76: 8019-8030.
19. Nexø BA, Vogel U, Olsen A, Nyegaard M, Bukowy Z, Rockenbauer E, Zhang X, Koca C, Mains M, Hansen B, Hedemand A, Kjeldgaard A, Laska MJ, Raaschou-Nielsen O, Cold S, Overvad K, Tjønneland A, Bolund L, Børglum AD. Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP. BMC Med Genet 2008; 9: 56.
20. Zeng Y. Principles of micro-RNA production and maturation. Oncogene 2006; 25: 6156-6162.
21. Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 2008; 6: 1741-7015.
22. Xu G, Wu J, Zhou L, Chen B, Sun Z, Zhao F, Tao Z. Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing. PLoS One 2010; 5: e15519.