-
1
-
-
28444439900
-
Organelle identity and the signposts for membrane traffic
-
Behnia, R., and S. Munro. 2005. Organelle identity and the signposts for membrane traffic. Nature. 438:597-604. http://dx.doi.org/10.1038/nature04397
-
(2005)
Nature.
, vol.438
, pp. 597-604
-
-
Behnia, R.1
Munro, S.2
-
2
-
-
0028018783
-
Analysis of cellular phosphoinositides and phosphoinositols by extraction and simple analytical procedures
-
Bird, I.M. 1994. Analysis of cellular phosphoinositides and phosphoinositols by extraction and simple analytical procedures. Methods Mol. Biol. 27:227-248.
-
(1994)
Methods Mol. Biol.
, vol.27
, pp. 227-248
-
-
Bird, I.M.1
-
3
-
-
0034062698
-
Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2
-
Bolino, A., M. Muglia, F.L. Conforti, E. LeGuern, M.A. Salih, D.M. Georgiou, K. Christodoulou, I. Hausmanowa-Petrusewicz, P. Mandich, A. Schenone, et al. 2000. Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2. Nat. Genet. 25:17-19. http://dx.doi.org/10.1038/75542
-
(2000)
Nat. Genet.
, vol.25
, pp. 17-19
-
-
Bolino, A.1
Muglia, M.2
Conforti, F.L.3
LeGuern, E.4
Salih, M.A.5
Georgiou, D.M.6
Christodoulou, K.7
Hausmanowa-Petrusewicz, I.8
Mandich, P.9
Schenone, A.10
-
4
-
-
22744434624
-
Cortactin promotes cell motility by enhancing lamellipodial persistence
-
Bryce, N.S., E.S. Clark, J.L. Leysath, J.D. Currie, D.J. Webb, and A.M. Weaver. 2005. Cortactin promotes cell motility by enhancing lamellipodial persistence. Curr. Biol. 15:1276-1285. http://dx.doi.org/10.1016/j.cub.2005.06.043
-
(2005)
Curr. Biol.
, vol.15
, pp. 1276-1285
-
-
Bryce, N.S.1
Clark, E.S.2
Leysath, J.L.3
Currie, J.D.4
Webb, D.J.5
Weaver, A.M.6
-
5
-
-
52649120304
-
Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia
-
Cai, L., A.M. Makhov, D.A. Schafer, and J.E. Bear. 2008. Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia. Cell. 134:828-842. http://dx.doi.org/10.1016/j.cell.2008.06.054
-
(2008)
Cell.
, vol.134
, pp. 828-842
-
-
Cai, L.1
Makhov, A.M.2
Schafer, D.A.3
Bear, J.E.4
-
6
-
-
84880888092
-
PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling
-
Cai, X., Y. Xu, A.K. Cheung, R.C. Tomlinson, A. Alcázar-Román, L. Murphy, A. Billich, B. Zhang, Y. Feng, M. Klumpp, et al. 2013. PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling. Chem. Biol. 20:912-921. http://dx.doi.org/10.1016/j.chembiol.2013.05.010
-
(2013)
Chem. Biol.
, vol.20
, pp. 912-921
-
-
Cai, X.1
Xu, Y.2
Cheung, A.K.3
Tomlinson, R.C.4
Alcázar-Román, A.5
Murphy, L.6
Billich, A.7
Zhang, B.8
Feng, Y.9
Klumpp, M.10
-
7
-
-
34447133038
-
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J
-
Chow, C.Y., Y. Zhang, J.J. Dowling, N. Jin, M. Adamska, K. Shiga, K. Szigeti, M.E. Shy, J. Li, X. Zhang, et al. 2007. Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J. Nature. 448:68-72. http://dx.doi.org/10.1038/nature05876
-
(2007)
Nature.
, vol.448
, pp. 68-72
-
-
Chow, C.Y.1
Zhang, Y.2
Dowling, J.J.3
Jin, N.4
Adamska, M.5
Shiga, K.6
Szigeti, K.7
Shy, M.E.8
Li, J.9
Zhang, X.10
-
8
-
-
67249143561
-
PIKfyve regulation of endosome-linked pathways
-
de Lartigue, J., H. Polson, M. Feldman, K. Shokat, S.A. Tooze, S. Urbé, and M.J. Clague. 2009. PIKfyve regulation of endosome-linked pathways. Traffic. 10:883-893. http://dx.doi.org/10.1111/j.1600-0854.2009.00915.x
-
(2009)
Traffic.
, vol.10
, pp. 883-893
-
-
de Lartigue, J.1
Polson, H.2
Feldman, M.3
Shokat, K.4
Tooze, S.A.5
Urbé, S.6
Clague, M.J.7
-
9
-
-
71549146571
-
The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex
-
Derivery, E., C. Sousa, J.J. Gautier, B. Lombard, D. Loew, and A. Gautreau. 2009. The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex. Dev. Cell. 17:712-723. http://dx.doi.org/10.1016/j.devcel.2009.09.010
-
(2009)
Dev. Cell.
, vol.17
, pp. 712-723
-
-
Derivery, E.1
Sousa, C.2
Gautier, J.J.3
Lombard, B.4
Loew, D.5
Gautreau, A.6
-
10
-
-
33749836234
-
Phosphoinositides in cell regulation and membrane dynamics
-
Di Paolo, G., and P. De Camilli. 2006. Phosphoinositides in cell regulation and membrane dynamics. Nature. 443:651-657. http://dx.doi.org/10.1038/nature05185
-
(2006)
Nature.
, vol.443
, pp. 651-657
-
-
Di Paolo, G.1
De Camilli, P.2
-
11
-
-
62749090535
-
Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function
-
Dove, S.K., K. Dong, T. Kobayashi, F.K. Williams, and R.H. Michell. 2009. Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function. Biochem. J. 419:1-13. http://dx.doi.org/10.1042/BJ20081950
-
(2009)
Biochem. J.
, vol.419
, pp. 1-13
-
-
Dove, S.K.1
Dong, K.2
Kobayashi, T.3
Williams, F.K.4
Michell, R.H.5
-
12
-
-
77949801905
-
WASH and the Arp2/3 complex regulate endosome shape and trafficking
-
Duleh, S.N., and M.D. Welch. 2010. WASH and the Arp2/3 complex regulate endosome shape and trafficking. Cytoskeleton (Hoboken). 67:193-206.
-
(2010)
Cytoskeleton (Hoboken).
, vol.67
, pp. 193-206
-
-
Duleh, S.N.1
Welch, M.D.2
-
13
-
-
70450162088
-
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2
-
Ferguson, C.J., G.M. Lenk, and M.H. Meisler. 2009. Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2. Hum. Mol. Genet. 18:4868-4878. http://dx.doi.org/10.1093/hmg/ddp460
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4868-4878
-
-
Ferguson, C.J.1
Lenk, G.M.2
Meisler, M.H.3
-
14
-
-
77953170746
-
GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation
-
Gandhi, M., B.A. Smith, M. Bovellan, V. Paavilainen, K. Daugherty-Clarke, J. Gelles, P. Lappalainen, and B.L. Goode. 2010. GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr. Biol. 20:861-867. http://dx.doi.org/10.1016/j.cub.2010.03.026
-
(2010)
Curr. Biol.
, vol.20
, pp. 861-867
-
-
Gandhi, M.1
Smith, B.A.2
Bovellan, M.3
Paavilainen, V.4
Daugherty-Clarke, K.5
Gelles, J.6
Lappalainen, P.7
Goode, B.L.8
-
15
-
-
33749037156
-
The ARP2/3 complex: an actin nucleator comes of age
-
Goley, E.D., and M.D. Welch. 2006. The ARP2/3 complex: an actin nucleator comes of age. Nat. Rev. Mol. Cell Biol. 7:713-726. http://dx.doi.org/10.1038/nrm2026
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 713-726
-
-
Goley, E.D.1
Welch, M.D.2
-
16
-
-
71549167371
-
A FAM21-containing WASH complex regulates retromer-dependent sorting
-
Gomez, T.S., and D.D. Billadeau. 2009. A FAM21-containing WASH complex regulates retromer-dependent sorting. Dev. Cell. 17:699-711. http://dx.doi.org/10.1016/j.devcel.2009.09.009
-
(2009)
Dev. Cell.
, vol.17
, pp. 699-711
-
-
Gomez, T.S.1
Billadeau, D.D.2
-
17
-
-
0035930328
-
Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity
-
Gournier, H., E.D. Goley, H. Niederstrasser, T. Trinh, and M.D. Welch. 2001. Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity. Mol. Cell. 8:1041-1052. http://dx.doi.org/10.1016/S1097-2765(01)00393-8
-
(2001)
Mol. Cell.
, vol.8
, pp. 1041-1052
-
-
Gournier, H.1
Goley, E.D.2
Niederstrasser, H.3
Trinh, T.4
Welch, M.D.5
-
18
-
-
17344380140
-
Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation
-
He, H., T. Watanabe, X. Zhan, C. Huang, E. Schuuring, K. Fukami, T. Takenawa, C.C. Kumar, R.J. Simpson, and H. Maruta. 1998. Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation. Mol. Cell. Biol. 18:3829-3837.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3829-3837
-
-
He, H.1
Watanabe, T.2
Zhan, X.3
Huang, C.4
Schuuring, E.5
Fukami, K.6
Takenawa, T.7
Kumar, C.C.8
Simpson, R.J.9
Maruta, H.10
-
19
-
-
84884676960
-
Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP
-
Helgeson, L.A., and B.J. Nolen. 2013. Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP. eLife. 2:e00884. http://dx.doi.org/10.7554/eLife.00884
-
(2013)
eLife
, vol.2
-
-
Helgeson, L.A.1
Nolen, B.J.2
-
20
-
-
84908110070
-
Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks
-
Helgeson, L.A., J.G. Prendergast, A.R. Wagner, M. Rodnick-Smith, and B.J. Nolen. 2014. Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks. J. Biol. Chem. 289:28856-28869. http://dx.doi.org/10.1074/jbc.M114.587527
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 28856-28869
-
-
Helgeson, L.A.1
Prendergast, J.G.2
Wagner, A.R.3
Rodnick-Smith, M.4
Nolen, B.J.5
-
21
-
-
84878261069
-
Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change
-
Hetrick, B., M.S. Han, L.A. Helgeson, and B.J. Nolen. 2013. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem. Biol. 20:701-712. http://dx.doi.org/10.1016/j.chembiol.2013.03.019
-
(2013)
Chem. Biol.
, vol.20
, pp. 701-712
-
-
Hetrick, B.1
Han, M.S.2
Helgeson, L.A.3
Nolen, B.J.4
-
22
-
-
33746586545
-
Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion
-
Ikonomov, O.C., D. Sbrissa, and A. Shisheva. 2006. Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion. Am. J. Physiol. Cell Physiol. 291:C393-C404. http://dx.doi.org/10.1152/ajpcell.00019.2006
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.291
, pp. C393-C404
-
-
Ikonomov, O.C.1
Sbrissa, D.2
Shisheva, A.3
-
24
-
-
3543074534
-
Cytoskeletal regulation: rich in lipids
-
Janmey, P.A., and U. Lindberg. 2004. Cytoskeletal regulation: rich in lipids. Nat. Rev. Mol. Cell Biol. 5:658-666. http://dx.doi.org/10.1038/nrm1434
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 658-666
-
-
Janmey, P.A.1
Lindberg, U.2
-
25
-
-
38949207192
-
A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding
-
Jefferies, H.B., F.T. Cooke, P. Jat, C. Boucheron, T. Koizumi, M. Hayakawa, H. Kaizawa, T. Ohishi, P. Workman, M.D. Waterfield, and P.J. Parker. 2008. A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding. EMBO Rep. 9:164-170. http://dx.doi.org/10.1038/sj.embor.7401155
-
(2008)
EMBO Rep.
, vol.9
, pp. 164-170
-
-
Jefferies, H.B.1
Cooke, F.T.2
Jat, P.3
Boucheron, C.4
Koizumi, T.5
Hayakawa, M.6
Kaizawa, H.7
Ohishi, T.8
Workman, P.9
Waterfield, M.D.10
Parker, P.J.11
-
26
-
-
77953757324
-
WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes
-
Jia, D., T.S. Gomez, Z. Metlagel, J. Umetani, Z. Otwinowski, M.K. Rosen, and D.D. Billadeau. 2010. WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes. Proc. Natl. Acad. Sci. USA. 107:10442-10447. http://dx.doi.org/10.1073/pnas.0913293107
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 10442-10447
-
-
Jia, D.1
Gomez, T.S.2
Metlagel, Z.3
Umetani, J.4
Otwinowski, Z.5
Rosen, M.K.6
Billadeau, D.D.7
-
27
-
-
58049198294
-
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse
-
Jin, N., C.Y. Chow, L. Liu, S.N. Zolov, R. Bronson, M. Davisson, J.L. Petersen, Y. Zhang, S. Park, and J.E. Duexet al. 2008. VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse. EMBO J. 27:3221-3234. http://dx.doi.org/10.1038/emboj.2008.248
-
(2008)
EMBO J.
, vol.27
, pp. 3221-3234
-
-
Jin, N.1
Chow, C.Y.2
Liu, L.3
Zolov, S.N.4
Bronson, R.5
Davisson, M.6
Petersen, J.L.7
Zhang, Y.8
Park, S.9
Duex, J.E.10
-
28
-
-
84962203624
-
Regulation of late endosomal/lysosomal maturation and trafficking by cortactin affects Golgi morphology
-
Cytoskeleton, Hoboken
-
Kirkbride, K.C., N.H. Hong, C.L. French, E.S. Clark, W.G. Jerome, and A.M. Weaver. 2012. Regulation of late endosomal/lysosomal maturation and trafficking by cortactin affects Golgi morphology. Cytoskeleton, Hoboken.
-
(2012)
-
-
Kirkbride, K.C.1
Hong, N.H.2
French, C.L.3
Clark, E.S.4
Jerome, W.G.5
Weaver, A.M.6
-
29
-
-
83055178382
-
A novel PIKFYVE mutation in fleck corneal dystrophy
-
Kotoulas, A., H. Kokotas, K. Kopsidas, K. Droutsas, M. Grigoriadou, H. Bajrami, D.F. Schorderet, and M.B. Petersen. 2011. A novel PIKFYVE mutation in fleck corneal dystrophy. Mol. Vis. 17:2776-2781.
-
(2011)
Mol. Vis.
, vol.17
, pp. 2776-2781
-
-
Kotoulas, A.1
Kokotas, H.2
Kopsidas, K.3
Droutsas, K.4
Grigoriadou, M.5
Bajrami, H.6
Schorderet, D.F.7
Petersen, M.B.8
-
30
-
-
77953762012
-
Translation of the phosphoinositide code by PI effectors
-
Kutateladze, T.G. 2010. Translation of the phosphoinositide code by PI effectors. Nat. Chem. Biol. 6:507-513. http://dx.doi.org/10.1038/nchembio.390
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 507-513
-
-
Kutateladze, T.G.1
-
31
-
-
41949088527
-
Arp2/3 complex interactions and actin network turnover in lamellipodia
-
Lai, F.P., M. Szczodrak, J. Block, J. Faix, D. Breitsprecher, H.G. Mannherz, T.E. Stradal, G.A. Dunn, J.V. Small, and K. Rottner. 2008. Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J. 27:982-992. http://dx.doi.org/10.1038/emboj.2008.34
-
(2008)
EMBO J.
, vol.27
, pp. 982-992
-
-
Lai, F.P.1
Szczodrak, M.2
Block, J.3
Faix, J.4
Breitsprecher, D.5
Mannherz, H.G.6
Stradal, T.E.7
Dunn, G.A.8
Small, J.V.9
Rottner, K.10
-
32
-
-
77649337122
-
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
-
Lee, J.Y., H. Koga, Y. Kawaguchi, W. Tang, E. Wong, Y.S. Gao, U.B. Pandey, S. Kaushik, E. Tresse, J. Lu, et al. 2010. HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. EMBO J. 29:969-980. http://dx.doi.org/10.1038/emboj.2009.405
-
(2010)
EMBO J.
, vol.29
, pp. 969-980
-
-
Lee, J.Y.1
Koga, H.2
Kawaguchi, Y.3
Tang, W.4
Wong, E.5
Gao, Y.S.6
Pandey, U.B.7
Kaushik, S.8
Tresse, E.9
Lu, J.10
-
33
-
-
84891368628
-
Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics
-
Li, X., X. Wang, X. Zhang, M. Zhao, W.L. Tsang, Y. Zhang, R.G. Yau, L.S. Weisman, and H. Xu. 2013. Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics. Proc. Natl. Acad. Sci. USA. 110:21165-21170. http://dx.doi.org/10.1073/pnas.1311864110
-
(2013)
Proc. Natl. Acad. Sci. USA.
, vol.110
, pp. 21165-21170
-
-
Li, X.1
Wang, X.2
Zhang, X.3
Zhao, M.4
Tsang, W.L.5
Zhang, Y.6
Yau, R.G.7
Weisman, L.S.8
Xu, H.9
-
34
-
-
38749091259
-
Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin
-
Lladó, A., P. Timpson, S. Vilà de Muga, J. Moretó, A. Pol, T. Grewal, R.J. Daly, C. Enrich, and F. Tebar. 2008. Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin. Mol. Biol. Cell. 19:17-29. http://dx.doi.org/10.1091/mbc.E07-05-0411
-
(2008)
Mol. Biol. Cell.
, vol.19
, pp. 17-29
-
-
Lladó, A.1
Timpson, P.2
Vilà de Muga, S.3
Moretó, J.4
Pol, A.5
Grewal, T.6
Daly, R.J.7
Enrich, C.8
Tebar, F.9
-
35
-
-
84883739514
-
Structural basis for regulation of Arp2/3 complex by GMF
-
Luan, Q., and B.J. Nolen. 2013. Structural basis for regulation of Arp2/3 complex by GMF. Nat. Struct. Mol. Biol. 20:1062-1068. http://dx.doi.org/10.1038/nsmb.2628
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1062-1068
-
-
Luan, Q.1
Nolen, B.J.2
-
36
-
-
0036082665
-
PIP(2) and proteins: interactions, organization, and information flow
-
McLaughlin, S., J. Wang, A. Gambhir, and D. Murray. 2002. PIP(2) and proteins: interactions, organization, and information flow. Annu. Rev. Biophys. Biomol. Struct. 31:151-175. http://dx.doi.org/10.1146/annurev.biophys.31.082901.134259
-
(2002)
Annu. Rev. Biophys. Biomol. Struct.
, vol.31
, pp. 151-175
-
-
McLaughlin, S.1
Wang, J.2
Gambhir, A.3
Murray, D.4
-
37
-
-
30944461203
-
Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
-
Michell, R.H., V.L. Heath, M.A. Lemmon, and S.K. Dove. 2006. Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions. Trends Biochem. Sci. 31:52-63. http://dx.doi.org/10.1016/j.tibs.2005.11.013
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 52-63
-
-
Michell, R.H.1
Heath, V.L.2
Lemmon, M.A.3
Dove, S.K.4
-
38
-
-
2642579936
-
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex
-
Millard, T.H., S.J. Sharp, and L.M. Machesky. 2004. Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex. Biochem. J. 380:1-17. http://dx.doi.org/10.1042/BJ20040176
-
(2004)
Biochem. J.
, vol.380
, pp. 1-17
-
-
Millard, T.H.1
Sharp, S.J.2
Machesky, L.M.3
-
39
-
-
84897950507
-
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
-
Monteiro, P., C. Rossé, A. Castro-Castro, M. Irondelle, E. Lagoutte, P. Paul-Gilloteaux, C. Desnos, E. Formstecher, F. Darchen, D. Perrais, et al. 2013. Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J. Cell Biol. 203:1063-1079. http://dx.doi.org/10.1083/jcb.201306162
-
(2013)
J. Cell Biol.
, vol.203
, pp. 1063-1079
-
-
Monteiro, P.1
Rossé, C.2
Castro-Castro, A.3
Irondelle, M.4
Lagoutte, E.5
Paul-Gilloteaux, P.6
Desnos, C.7
Formstecher, E.8
Darchen, F.9
Perrais, D.10
-
40
-
-
0033775855
-
Latrunculin alters the actin-monomer subunit interface to prevent polymerization
-
Morton, W.M., K.R. Ayscough, and P.J. McLaughlin. 2000. Latrunculin alters the actin-monomer subunit interface to prevent polymerization. Nat. Cell Biol. 2:376-378. http://dx.doi.org/10.1038/35014075
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 376-378
-
-
Morton, W.M.1
Ayscough, K.R.2
McLaughlin, P.J.3
-
41
-
-
33745584383
-
The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans
-
Nicot, A.S., H. Fares, B. Payrastre, A.D. Chisholm, M. Labouesse, and J. Laporte. 2006. The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans. Mol. Biol. Cell. 17:3062-3074.
-
(2006)
Mol. Biol. Cell.
, vol.17
, pp. 3062-3074
-
-
Nicot, A.S.1
Fares, H.2
Payrastre, B.3
Chisholm, A.D.4
Labouesse, M.5
Laporte, J.6
-
42
-
-
69249212192
-
Characterization of two classes of small molecule inhibitors of Arp2/3 complex
-
Nolen, B.J., N. Tomasevic, A. Russell, D.W. Pierce, Z. Jia, C.D. McCormick, J. Hartman, R. Sakowicz, and T.D. Pollard. 2009. Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature. 460:1031-1034. http://dx.doi.org/10.1038/nature08231
-
(2009)
Nature.
, vol.460
, pp. 1031-1034
-
-
Nolen, B.J.1
Tomasevic, N.2
Russell, A.3
Pierce, D.W.4
Jia, Z.5
McCormick, C.D.6
Hartman, J.7
Sakowicz, R.8
Pollard, T.D.9
-
43
-
-
79956299299
-
Receptor sorting within endosomal trafficking pathway is facilitated by dynamic actin filaments
-
Ohashi, E., K. Tanabe, Y. Henmi, K. Mesaki, Y. Kobayashi, and K. Takei. 2011. Receptor sorting within endosomal trafficking pathway is facilitated by dynamic actin filaments. PLoS ONE. 6:e19942. http://dx.doi.org/10.1371/journal.pone.0019942
-
(2011)
PLoS ONE.
, vol.6
-
-
Ohashi, E.1
Tanabe, K.2
Henmi, Y.3
Mesaki, K.4
Kobayashi, Y.5
Takei, K.6
-
44
-
-
2342552557
-
3 binding is necessary for WAVE2-induced formation of lamellipodia
-
3 binding is necessary for WAVE2-induced formation of lamellipodia. Nat. Cell Biol. 6:420-426. http://dx.doi.org/10.1038/ncb1125
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 420-426
-
-
Oikawa, T.1
Yamaguchi, H.2
Itoh, T.3
Kato, M.4
Ijuin, T.5
Yamazaki, D.6
Suetsugu, S.7
Takenawa, T.8
-
45
-
-
84866144210
-
Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases
-
Otomo, A., L. Pan, and S. Hadano. 2012. Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases. Neurol. Res. Int. 2012:498428. http://dx.doi.org/10.1155/2012/498428
-
(2012)
Neurol. Res. Int.
, vol.2012
, pp. 498428
-
-
Otomo, A.1
Pan, L.2
Hadano, S.3
-
46
-
-
12344337525
-
A polybasic motif allows N-WASP to act as a sensor of PIP(2) density
-
Papayannopoulos, V., C. Co, K.E. Prehoda, S. Snapper, J. Taunton, and W.A. Lim. 2005. A polybasic motif allows N-WASP to act as a sensor of PIP(2) density. Mol. Cell. 17:181-191. http://dx.doi.org/10.1016/j.molcel.2004.11.054
-
(2005)
Mol. Cell.
, vol.17
, pp. 181-191
-
-
Papayannopoulos, V.1
Co, C.2
Prehoda, K.E.3
Snapper, S.4
Taunton, J.5
Lim, W.A.6
-
47
-
-
79251527516
-
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains
-
Puthenveedu, M.A., B. Lauffer, P. Temkin, R. Vistein, P. Carlton, K. Thorn, J. Taunton, O.D. Weiner, R.G. Parton, and M. von Zastrow. 2010. Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell. 143:761-773. http://dx.doi.org/10.1016/j.cell.2010.10.003
-
(2010)
Cell.
, vol.143
, pp. 761-773
-
-
Puthenveedu, M.A.1
Lauffer, B.2
Temkin, P.3
Vistein, R.4
Carlton, P.5
Thorn, K.6
Taunton, J.7
Weiner, O.D.8
Parton, R.G.9
von Zastrow, M.10
-
48
-
-
0034683746
-
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
-
Rohatgi, R., H.Y. Ho, and M.W. Kirschner. 2000. Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J. Cell Biol. 150:1299-1310. http://dx.doi.org/10.1083/jcb.150.6.1299
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1299-1310
-
-
Rohatgi, R.1
Ho, H.Y.2
Kirschner, M.W.3
-
49
-
-
84899800579
-
Control of MT1-MMP transport by atypical PKC during breast-cancer progression
-
Rossé, C., C. Lodillinsky, L. Fuhrmann, M. Nourieh, P. Monteiro, M. Irondelle, E. Lagoutte, S. Vacher, F. Waharte, P. Paul-Gilloteaux, et al. 2014. Control of MT1-MMP transport by atypical PKC during breast-cancer progression. Proc. Natl. Acad. Sci. USA. 111:E1872-E1879. http://dx.doi.org/10.1073/pnas.1400749111
-
(2014)
Proc. Natl. Acad. Sci. USA.
, vol.111
, pp. E1872-E1879
-
-
Rossé, C.1
Lodillinsky, C.2
Fuhrmann, L.3
Nourieh, M.4
Monteiro, P.5
Irondelle, M.6
Lagoutte, E.7
Vacher, S.8
Waharte, F.9
Paul-Gilloteaux, P.10
-
50
-
-
0346729925
-
Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase
-
Rudge, S.A., D.M. Anderson, and S.D. Emr. 2004. Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol. Biol. Cell. 15:24-36. http://dx.doi.org/10.1091/mbc.E03-05-0297
-
(2004)
Mol. Biol. Cell.
, vol.15
, pp. 24-36
-
-
Rudge, S.A.1
Anderson, D.M.2
Emr, S.D.3
-
51
-
-
33748320774
-
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
-
Rusten, T.E., L.M. Rodahl, K. Pattni, C. Englund, C. Samakovlis, S. Dove, A. Brech, and H. Stenmark. 2006. Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Mol. Biol. Cell. 17:3989-4001. http://dx.doi.org/10.1091/mbc.E06-03-0239
-
(2006)
Mol. Biol. Cell.
, vol.17
, pp. 3989-4001
-
-
Rusten, T.E.1
Rodahl, L.M.2
Pattni, K.3
Englund, C.4
Samakovlis, C.5
Dove, S.6
Brech, A.7
Stenmark, H.8
-
52
-
-
33750485772
-
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
-
Rutherford, A.C., C. Traer, T. Wassmer, K. Pattni, M.V. Bujny, J.G. Carlton, H. Stenmark, and P.J. Cullen. 2006. The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J. Cell Sci. 119:3944-3957. http://dx.doi.org/10.1242/jcs.03153
-
(2006)
J. Cell Sci.
, vol.119
, pp. 3944-3957
-
-
Rutherford, A.C.1
Traer, C.2
Wassmer, T.3
Pattni, K.4
Bujny, M.V.5
Carlton, J.G.6
Stenmark, H.7
Cullen, P.J.8
-
53
-
-
74949100104
-
Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides
-
Saarikangas, J., H. Zhao, and P. Lappalainen. 2010. Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides. Physiol. Rev. 90:259-289. http://dx.doi.org/10.1152/physrev.00036.2009
-
(2010)
Physiol. Rev.
, vol.90
, pp. 259-289
-
-
Saarikangas, J.1
Zhao, H.2
Lappalainen, P.3
-
54
-
-
43249117879
-
PIKfyve: Partners, significance, debates and paradoxes
-
Shisheva, A. 2008. PIKfyve: Partners, significance, debates and paradoxes. Cell Biol. Int. 32:591-604. http://dx.doi.org/10.1016/j.cellbi.2008.01.006
-
(2008)
Cell Biol. Int.
, vol.32
, pp. 591-604
-
-
Shisheva, A.1
-
55
-
-
84155163062
-
Cortactin releases the brakes in actin-based motility by enhancing WASP-VCA detachment from Arp2/3 branches
-
Siton, O., Y. Ideses, S. Albeck, T. Unger, A.D. Bershadsky, N.S. Gov, and A. Bernheim-Groswasser. 2011. Cortactin releases the brakes in actin-based motility by enhancing WASP-VCA detachment from Arp2/3 branches. Curr. Biol. 21:2092-2097. http://dx.doi.org/10.1016/j.cub.2011.11.010
-
(2011)
Curr. Biol.
, vol.21
, pp. 2092-2097
-
-
Siton, O.1
Ideses, Y.2
Albeck, S.3
Unger, T.4
Bershadsky, A.D.5
Gov, N.S.6
Bernheim-Groswasser, A.7
-
56
-
-
33646763140
-
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac
-
Suetsugu, S., S. Kurisu, T. Oikawa, D. Yamazaki, A. Oda, and T. Takenawa. 2006. Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac. J. Cell Biol. 173:571-585. http://dx.doi.org/10.1083/jcb.200509067
-
(2006)
J. Cell Biol.
, vol.173
, pp. 571-585
-
-
Suetsugu, S.1
Kurisu, S.2
Oikawa, T.3
Yamazaki, D.4
Oda, A.5
Takenawa, T.6
-
57
-
-
80052821897
-
Cortactin controls cell motility and lamellipodial dynamics by regulating ECM secretion
-
Sung, B.H., X. Zhu, I. Kaverina, and A.M. Weaver. 2011. Cortactin controls cell motility and lamellipodial dynamics by regulating ECM secretion. Curr. Biol. 21:1460-1469. http://dx.doi.org/10.1016/j.cub.2011.06.065
-
(2011)
Curr. Biol.
, vol.21
, pp. 1460-1469
-
-
Sung, B.H.1
Zhu, X.2
Kaverina, I.3
Weaver, A.M.4
-
58
-
-
84881079933
-
Receptor sorting and actin dynamics at early endosomes
-
Tanabe, K., E. Ohashi, Y. Henmi, and K. Takei. 2011. Receptor sorting and actin dynamics at early endosomes. Commun. Integr. Biol. 4:742-744. http://dx.doi.org/10.4161/cib.17628
-
(2011)
Commun. Integr. Biol.
, vol.4
, pp. 742-744
-
-
Tanabe, K.1
Ohashi, E.2
Henmi, Y.3
Takei, K.4
-
59
-
-
17144399942
-
Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor
-
Timpson, P., D.K. Lynch, D. Schramek, F. Walker, and R.J. Daly. 2005. Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor. Cancer Res. 65:3273-3280.
-
(2005)
Cancer Res.
, vol.65
, pp. 3273-3280
-
-
Timpson, P.1
Lynch, D.K.2
Schramek, D.3
Walker, F.4
Daly, R.J.5
-
60
-
-
0035090317
-
Activation of Arp2/3 complex-mediated actin polymerization by cortactin
-
Uruno, T., J. Liu, P. Zhang, Y. Fan Yx, C. Egile, R. Li, S.C. Mueller, and X. Zhan. 2001. Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat. Cell Biol. 3:259-266. http://dx.doi.org/10.1038/35060051
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 259-266
-
-
Uruno, T.1
Liu, J.2
Zhang, P.3
Fan Yx, Y.4
Egile, C.5
Li, R.6
Mueller, S.C.7
Zhan, X.8
-
61
-
-
0037830419
-
Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation
-
Uruno, T., J. Liu, Y. Li, N. Smith, and X. Zhan. 2003. Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation. J. Biol. Chem. 278:26086-26093. http://dx.doi.org/10.1074/jbc.M301997200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26086-26093
-
-
Uruno, T.1
Liu, J.2
Li, Y.3
Smith, N.4
Zhan, X.5
-
62
-
-
0242580785
-
Alternative splicing of the actin binding domain of human cortactin affects cell migration
-
van Rossum, A.G., J.H. de Graaf, E. Schuuring-Scholtes, P.M. Kluin, Y.X. Fan, X. Zhan, W.H. Moolenaar, and E. Schuuring. 2003. Alternative splicing of the actin binding domain of human cortactin affects cell migration. J. Biol. Chem. 278:45672-45679. http://dx.doi.org/10.1074/jbc.M306688200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45672-45679
-
-
van Rossum, A.G.1
de Graaf, J.H.2
Schuuring-Scholtes, E.3
Kluin, P.M.4
Fan, Y.X.5
Zhan, X.6
Moolenaar, W.H.7
Schuuring, E.8
-
63
-
-
0035814938
-
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
-
Weaver, A.M., A.V. Karginov, A.W. Kinley, S.A. Weed, Y. Li, J.T. Parsons, and J.A. Cooper. 2001. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr. Biol. 11:370-374. http://dx.doi.org/10.1016/S0960-9822(01)00098-7
-
(2001)
Curr. Biol.
, vol.11
, pp. 370-374
-
-
Weaver, A.M.1
Karginov, A.V.2
Kinley, A.W.3
Weed, S.A.4
Li, Y.5
Parsons, J.T.6
Cooper, J.A.7
-
64
-
-
0037031144
-
Interaction of cortactin and N-WASp with Arp2/3 complex
-
Weaver, A.M., J.E. Heuser, A.V. Karginov, W.L. Lee, J.T. Parsons, and J.A. Cooper. 2002. Interaction of cortactin and N-WASp with Arp2/3 complex. Curr. Biol. 12:1270-1278. http://dx.doi.org/10.1016/S0960-9822(02)01035-7
-
(2002)
Curr. Biol.
, vol.12
, pp. 1270-1278
-
-
Weaver, A.M.1
Heuser, J.E.2
Karginov, A.V.3
Lee, W.L.4
Parsons, J.T.5
Cooper, J.A.6
-
65
-
-
0034597092
-
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex
-
Weed, S.A., A.V. Karginov, D.A. Schafer, A.M. Weaver, A.W. Kinley, J.A. Cooper, and J.T. Parsons. 2000. Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J. Cell Biol. 151:29-40.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 29-40
-
-
Weed, S.A.1
Karginov, A.V.2
Schafer, D.A.3
Weaver, A.M.4
Kinley, A.W.5
Cooper, J.A.6
Parsons, J.T.7
-
66
-
-
0025940103
-
Identification and characterization of a novel cytoskeleton-associated pp60src substrate
-
Wu, H., A.B. Reynolds, S.B. Kanner, R.R. Vines, and J.T. Parsons. 1991. Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol. 11:5113-5124.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 5113-5124
-
-
Wu, H.1
Reynolds, A.B.2
Kanner, S.B.3
Vines, R.R.4
Parsons, J.T.5
-
67
-
-
84879309319
-
GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism
-
Ydenberg, C.A., S.B. Padrick, M.O. Sweeney, M. Gandhi, O. Sokolova, and B.L. Goode. 2013. GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism. Curr. Biol. 23:1037-1045. http://dx.doi.org/10.1016/j.cub.2013.04.058
-
(2013)
Curr. Biol.
, vol.23
, pp. 1037-1045
-
-
Ydenberg, C.A.1
Padrick, S.B.2
Sweeney, M.O.3
Gandhi, M.4
Sokolova, O.5
Goode, B.L.6
-
68
-
-
0038311944
-
Phosphoinositide regulation of the actin cytoskeleton
-
Yin, H.L., and P.A. Janmey. 2003. Phosphoinositide regulation of the actin cytoskeleton. Annu. Rev. Physiol. 65:761-789. http://dx.doi.org/10.1146/annurev.physiol.65.092101.142517
-
(2003)
Annu. Rev. Physiol.
, vol.65
, pp. 761-789
-
-
Yin, H.L.1
Janmey, P.A.2
-
69
-
-
84867908738
-
2, which serves as both a signaling lipid and the major precursor for PI5P
-
2, which serves as both a signaling lipid and the major precursor for PI5P. Proc. Natl. Acad. Sci. USA. 109:17472-17477. http://dx.doi.org/10.1073/pnas.1203106109
-
(2012)
Proc. Natl. Acad. Sci. USA.
, vol.109
, pp. 17472-17477
-
-
Zolov, S.N.1
Bridges, D.2
Zhang, Y.3
Lee, W.W.4
Riehle, E.5
Verma, R.6
Lenk, G.M.7
Converso-Baran, K.8
Weide, T.9
Albin, R.L.10
|