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Volumn 185, Issue , 2016, Pages 243-254

Increased involvement of Panax notoginseng in the mechanism of decreased hepatotoxicity induced by Tripterygium wilfordii in rats

Author keywords

Mechanism of reducing hepatotoxicity; Metabonomics technology; Panax notoginseng; Pharmacokinetics characteristics; Tripterygium wilfordii; Usage compatibility

Indexed keywords

PANAX NOTOGINSENG EXTRACT; TRIPTOLIDE; PLANT EXTRACT;

EID: 84961878072     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.03.027     Document Type: Article
Times cited : (20)

References (41)
  • 2
    • 0028019267 scopus 로고
    • Tiglylglycine excreted in urine in disorders of isoleucine metabolism and the respiratory chain measured by stable isotope dilution GC-MS
    • M.J. Bennett, S. Powell, D.J. Swartling, and K.M. Gibson Tiglylglycine excreted in urine in disorders of isoleucine metabolism and the respiratory chain measured by stable isotope dilution GC-MS Clin. Chem. 40 1994 1879 1883
    • (1994) Clin. Chem. , vol.40 , pp. 1879-1883
    • Bennett, M.J.1    Powell, S.2    Swartling, D.J.3    Gibson, K.M.4
  • 3
    • 73449132248 scopus 로고    scopus 로고
    • Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis
    • M. Cameron, J.J. Gagnier, C.V. Little, T.J. Parsons, A. Blümle, and S. Chrubasik Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis Phytother. Res. 23 2009 1647 1662
    • (2009) Phytother. Res. , vol.23 , pp. 1647-1662
    • Cameron, M.1    Gagnier, J.J.2    Little, C.V.3    Parsons, T.J.4    Blümle, A.5    Chrubasik, S.6
  • 4
    • 69249140995 scopus 로고    scopus 로고
    • Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations
    • J. Chen, W. Wang, S. Lv, P. Yin, X. Zhao, X. Lu, F. Zhang, and G. Xu Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations Anal. Chim. Acta 650 2009 3 9
    • (2009) Anal. Chim. Acta , vol.650 , pp. 3-9
    • Chen, J.1    Wang, W.2    Lv, S.3    Yin, P.4    Zhao, X.5    Lu, X.6    Zhang, F.7    Xu, G.8
  • 5
    • 0037334146 scopus 로고    scopus 로고
    • A randomized double blind, placebo controlled trial of topical Tripterygium wilfordii in rheumatoid arthritis: Reanalysis using logistic regression analysis
    • J. Cibere, Z. Deng, Y. Lin, R. Ou, Y. He, Z. Wang, A. Thorne, A.J. Lehman, I.K. Tsang, and J.M. Esdaile A randomized double blind, placebo controlled trial of topical Tripterygium wilfordii in rheumatoid arthritis: reanalysis using logistic regression analysis J. Rheumatol. 30 2003 465 467
    • (2003) J. Rheumatol. , vol.30 , pp. 465-467
    • Cibere, J.1    Deng, Z.2    Lin, Y.3    Ou, R.4    He, Y.5    Wang, Z.6    Thorne, A.7    Lehman, A.J.8    Tsang, I.K.9    Esdaile, J.M.10
  • 6
    • 84961900637 scopus 로고    scopus 로고
    • Study on HPLC Fingerprint of Tripterygium wilfordii
    • L.-y. Dong, Q.-w. Zhang, and H.-q. Duan Study on HPLC Fingerprint of Tripterygium wilfordii Chin. Pharm. J. 6 2009 011
    • (2009) Chin. Pharm. J. , vol.6 , pp. 011
    • Dong, L.-Y.1    Zhang, Q.-W.2    Duan, H.-Q.3
  • 7
    • 33746872939 scopus 로고    scopus 로고
    • Gas chromatography/flame ionisation detection mass spectrometry for the detection of endogenous urine metabolites for metabonomic studies and its use as a complementary tool to nuclear magnetic resonance spectroscopy
    • S.A. Fancy, O. Beckonert, G. Darbon, W. Yabsley, R. Walley, D. Baker, G.L. Perkins, F.S. Pullen, and K. Rumpel Gas chromatography/flame ionisation detection mass spectrometry for the detection of endogenous urine metabolites for metabonomic studies and its use as a complementary tool to nuclear magnetic resonance spectroscopy Rapid Commun. Mass Spectrom. 20 2006 2271 2280
    • (2006) Rapid Commun. Mass Spectrom. , vol.20 , pp. 2271-2280
    • Fancy, S.A.1    Beckonert, O.2    Darbon, G.3    Yabsley, W.4    Walley, R.5    Baker, D.6    Perkins, G.L.7    Pullen, F.S.8    Rumpel, K.9
  • 8
    • 84880587577 scopus 로고    scopus 로고
    • Mass spectrum selectivity-based chromatogram baseline-shift elimination and its application in metabonomics of liver toxicity
    • J.-J. Feng, T. Lv, L. Liu, L. Xie, Y.-W. Xing, C.-Y. Min, and H.-P. Xie Mass spectrum selectivity-based chromatogram baseline-shift elimination and its application in metabonomics of liver toxicity Chemom. Intell. Lab. Syst. 127 2013 112 120
    • (2013) Chemom. Intell. Lab. Syst. , vol.127 , pp. 112-120
    • Feng, J.-J.1    Lv, T.2    Liu, L.3    Xie, L.4    Xing, Y.-W.5    Min, C.-Y.6    Xie, H.-P.7
  • 9
    • 0031748093 scopus 로고    scopus 로고
    • The metabolism of homocysteine: Pathways and regulation
    • J. Finkelstein The metabolism of homocysteine: pathways and regulation Eur. J. Pediatr. 157 1998 S40 S44
    • (1998) Eur. J. Pediatr. , vol.157 , pp. S40-S44
    • Finkelstein, J.1
  • 10
    • 42149172676 scopus 로고    scopus 로고
    • Comparison between the characteristics of absorption and pharmacokinetic behavior of ginsenoside Rg1 and ginsenoside Rb, of Panax notoginseng saponins
    • M. Han, S. Fu, and X. Fang Comparison between the characteristics of absorption and pharmacokinetic behavior of ginsenoside Rg1 and ginsenoside Rb, of Panax notoginseng saponins Yao Xue Xue Bao 42 2007 849 853
    • (2007) Yao Xue Xue Bao , vol.42 , pp. 849-853
    • Han, M.1    Fu, S.2    Fang, X.3
  • 11
    • 84922686108 scopus 로고    scopus 로고
    • Effect of notoginseng extracts and their components on lipopolysaccharide and galactosamine mixture-induced impaired hepatic function in mice
    • K.-i. Komatsu, H. Tanaka, D. Nakagawa, and K. Kawashima Effect of notoginseng extracts and their components on lipopolysaccharide and galactosamine mixture-induced impaired hepatic function in mice Yakugaku Zasshi 132 2011 831 836
    • (2011) Yakugaku Zasshi , vol.132 , pp. 831-836
    • Komatsu, K.-I.1    Tanaka, H.2    Nakagawa, D.3    Kawashima, K.4
  • 12
    • 79955685378 scopus 로고    scopus 로고
    • Comparison of toxic reaction of Tripterygium wilfordii multiglycoside in normal and adjuvant arthritic rats
    • J. Li, Y. Lu, C. Xiao, C. Lu, X. Niu, X. He, H. Zhao, Y. Tan, and A. Lu Comparison of toxic reaction of Tripterygium wilfordii multiglycoside in normal and adjuvant arthritic rats J. Ethnopharmacol. 135 2011 270 277
    • (2011) J. Ethnopharmacol. , vol.135 , pp. 270-277
    • Li, J.1    Lu, Y.2    Xiao, C.3    Lu, C.4    Niu, X.5    He, X.6    Zhao, H.7    Tan, Y.8    Lu, A.9
  • 13
    • 84905007521 scopus 로고    scopus 로고
    • Triptolide: Progress on research in pharmacodynamics and toxicology
    • X.-J. Li, Z.-Z. Jiang, and L.-y. Zhang Triptolide: progress on research in pharmacodynamics and toxicology J. Ethnopharmacol. 155 2014 67 79
    • (2014) J. Ethnopharmacol. , vol.155 , pp. 67-79
    • Li, X.-J.1    Jiang, Z.-Z.2    Zhang, L.-Y.3
  • 14
    • 84921649784 scopus 로고    scopus 로고
    • Investigation of the active components in Tripterygium wilfordii leading to its acute hepatotoxicty and nephrotoxicity
    • X.-X. Li, F.-Y. Du, H.-X. Liu, J.-B. Ji, and J. Xing Investigation of the active components in Tripterygium wilfordii leading to its acute hepatotoxicty and nephrotoxicity J. Ethnopharmacol. 162 2015 238 243
    • (2015) J. Ethnopharmacol. , vol.162 , pp. 238-243
    • Li, X.-X.1    Du, F.-Y.2    Liu, H.-X.3    Ji, J.-B.4    Xing, J.5
  • 15
    • 42949144979 scopus 로고    scopus 로고
    • Toxicity attenuation and efficacy potentiation effect of liquorice on treatment of rheumatoid arthritis with Tripterygium wilfordii
    • Y.-S. Li, P.-J. Tong, and H.-Z. Ma Toxicity attenuation and efficacy potentiation effect of liquorice on treatment of rheumatoid arthritis with Tripterygium wilfordii Zhongguo Zhong Xi Yi Jie He Za Zhi 26 2006 1117 1119
    • (2006) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.26 , pp. 1117-1119
    • Li, Y.-S.1    Tong, P.-J.2    Ma, H.-Z.3
  • 16
    • 13544268520 scopus 로고    scopus 로고
    • Anti-inflammatory effects of triptolide loaded poly (D, l-lactic acid) nanoparticles on adjuvant-induced arthritis in rats
    • M. Liu, J. Dong, Y. Yang, X. Yang, and H. Xu Anti-inflammatory effects of triptolide loaded poly (D, l-lactic acid) nanoparticles on adjuvant-induced arthritis in rats J. Ethnopharmacol. 97 2005 219 225
    • (2005) J. Ethnopharmacol. , vol.97 , pp. 219-225
    • Liu, M.1    Dong, J.2    Yang, Y.3    Yang, X.4    Xu, H.5
  • 17
    • 84978400003 scopus 로고    scopus 로고
    • Chemical basis of Tripterygium wilfordii compatibility for attenuation in qingluo tongbi decoction
    • M.Z. Liu, X.L. Zhang, and H.X. Zhu Chemical basis of Tripterygium wilfordii compatibility for attenuation in qingluo tongbi decoction Chin. J. Exp. Tradit. Med. Formulae 7 2014 107 112
    • (2014) Chin. J. Exp. Tradit. Med. Formulae , vol.7 , pp. 107-112
    • Liu, M.Z.1    Zhang, X.L.2    Zhu, H.X.3
  • 18
    • 84882245158 scopus 로고    scopus 로고
    • Urinary metabonomics study on toxicity biomarker discovery in rats treated with Xanthii fructus
    • F. Lu, M. Cao, B. Wu, X.-z. Li, H.-y. Liu, D.-z. Chen, and S.-m. Liu Urinary metabonomics study on toxicity biomarker discovery in rats treated with Xanthii fructus J. Ethnopharmacol. 149 2013 311 320
    • (2013) J. Ethnopharmacol. , vol.149 , pp. 311-320
    • Lu, F.1    Cao, M.2    Wu, B.3    Li, X.-Z.4    Liu, H.-Y.5    Chen, D.-Z.6    Liu, S.-M.7
  • 19
    • 15944406461 scopus 로고    scopus 로고
    • The research on the anti-inflammatory activity and hepatotoxicity of triptolide-loaded solid lipid nanoparticle
    • Z. Mei, X. Li, Q. Wu, S. Hu, and X. Yang The research on the anti-inflammatory activity and hepatotoxicity of triptolide-loaded solid lipid nanoparticle Pharmacol. Res. 51 2005 345 351
    • (2005) Pharmacol. Res. , vol.51 , pp. 345-351
    • Mei, Z.1    Li, X.2    Wu, Q.3    Hu, S.4    Yang, X.5
  • 22
    • 0017665136 scopus 로고
    • The conversion of d-xylose into d-threitol in patients without liver disease and in patients with portal liver cirrhosis
    • E. Pitkänen The conversion of d-xylose into d-threitol in patients without liver disease and in patients with portal liver cirrhosis Clin. Chim. Acta 80 1977 49 54
    • (1977) Clin. Chim. Acta , vol.80 , pp. 49-54
    • Pitkänen, E.1
  • 23
    • 0025612504 scopus 로고
    • Gas chromatographic-mass spectrometric characterisation of unsaturated dicarboxylic acids in urine
    • J. Pitt Gas chromatographic-mass spectrometric characterisation of unsaturated dicarboxylic acids in urine J. Chromatogr. B: Biomed. Sci. Appl. 534 1990 182 189
    • (1990) J. Chromatogr. B: Biomed. Sci. Appl. , vol.534 , pp. 182-189
    • Pitt, J.1
  • 24
    • 0002886643 scopus 로고    scopus 로고
    • Hepatoprotective effects of Panax notoginseng: Ginsenosides-Re and - Rg 1 as its active constituents in d-galactosamine/lipopolysaccharide-induced liver injury
    • J. Prasain, S. Kadota, P. Basnet, K. Hase, and T. Namba Hepatoprotective effects of Panax notoginseng: Ginsenosides-Re and - Rg 1 as its active constituents in d-galactosamine/lipopolysaccharide-induced liver injury Phytomedicine 2 1996 297 303
    • (1996) Phytomedicine , vol.2 , pp. 297-303
    • Prasain, J.1    Kadota, S.2    Basnet, P.3    Hase, K.4    Namba, T.5
  • 25
    • 52649089254 scopus 로고    scopus 로고
    • Advances in studies compatibility applied toattenuation and synergy of Tripterygium wilfordii
    • Y. Rao, H. Wei, Y. Chen, H. Fang, S. Zhu, Y. Wu, and J. Zhang Advances in studies compatibility applied toattenuation and synergy of Tripterygium wilfordii Zhongguo Zhong Yao Za Zhi 33 2008 1658 1661
    • (2008) Zhongguo Zhong Yao Za Zhi , vol.33 , pp. 1658-1661
    • Rao, Y.1    Wei, H.2    Chen, Y.3    Fang, H.4    Zhu, S.5    Wu, Y.6    Zhang, J.7
  • 26
    • 78650907092 scopus 로고    scopus 로고
    • Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
    • A. Roux, D. Lison, C. Junot, and J.-F. Heilier Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: a review Clin. Biochem. 44 2011 119 135
    • (2011) Clin. Biochem. , vol.44 , pp. 119-135
    • Roux, A.1    Lison, D.2    Junot, C.3    Heilier, J.-F.4
  • 27
    • 34147187917 scopus 로고    scopus 로고
    • Pharmacokinetic study of triptolide, a constituent of immunosuppressive Chinese herb medicine, in rats
    • F. Shao, G. Wang, H. Xie, X. Zhu, and J. Sun Pharmacokinetic study of triptolide, a constituent of immunosuppressive Chinese herb medicine, in rats Biol. Pharm. Bull. 30 2007 702 707
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 702-707
    • Shao, F.1    Wang, G.2    Xie, H.3    Zhu, X.4    Sun, J.5
  • 30
    • 31644440532 scopus 로고    scopus 로고
    • Analysis of polyols in urine by liquid chromatography-tandem mass spectrometry: A useful tool for recognition of inborn errors affecting polyol metabolism
    • M. Wamelink, D. Smith, C. Jakobs, and N. Verhoeven Analysis of polyols in urine by liquid chromatography-tandem mass spectrometry: a useful tool for recognition of inborn errors affecting polyol metabolism J. Inherit. Metab. Dis. 28 2005 951 963
    • (2005) J. Inherit. Metab. Dis. , vol.28 , pp. 951-963
    • Wamelink, M.1    Smith, D.2    Jakobs, C.3    Verhoeven, N.4
  • 31
    • 84862821255 scopus 로고    scopus 로고
    • Transdermal microemulsion drug delivery system for impairing male reproductive toxicity and enhancing efficacy of Tripterygium wilfordii Hook f
    • X. Wang, M. Xue, J. Gu, X. Fang, and X. Sha Transdermal microemulsion drug delivery system for impairing male reproductive toxicity and enhancing efficacy of Tripterygium wilfordii Hook f Fitoterapia 83 2012 690 698
    • (2012) Fitoterapia , vol.83 , pp. 690-698
    • Wang, X.1    Xue, M.2    Gu, J.3    Fang, X.4    Sha, X.5
  • 32
    • 68849095597 scopus 로고    scopus 로고
    • Heat shock protein 72 protects kidney proximal tubule cells from injury induced by triptolide by means of activation of the MEK/ERK pathway
    • Z. Wang, H. Jin, C. Li, Y. Hou, Q. Mei, and D. Fan Heat shock protein 72 protects kidney proximal tubule cells from injury induced by triptolide by means of activation of the MEK/ERK pathway Int. J. Toxicol. 28 2009 177 189
    • (2009) Int. J. Toxicol. , vol.28 , pp. 177-189
    • Wang, Z.1    Jin, H.2    Li, C.3    Hou, Y.4    Mei, Q.5    Fan, D.6
  • 33
    • 54949151426 scopus 로고    scopus 로고
    • Anti-tumour and immuno-modulation effects of triptolide-loaded polymeric micelles
    • L. Xu, H. Chen, H. Xu, and X. Yang Anti-tumour and immuno-modulation effects of triptolide-loaded polymeric micelles Eur. J. Pharm. Biopharm. 70 2008 741 748
    • (2008) Eur. J. Pharm. Biopharm. , vol.70 , pp. 741-748
    • Xu, L.1    Chen, H.2    Xu, H.3    Yang, X.4
  • 34
    • 84865236833 scopus 로고    scopus 로고
    • Anti-inflammatory effects and hepatotoxicity of Tripterygium-loaded solid lipid nanoparticles on adjuvant-induced arthritis in rats
    • M. Xue, Z.-z. Jiang, T. Wu, J. Li, L. Zhang, Y. Zhao, X.-j. Li, L.-Y. Zhang, and S.-y. Yang Anti-inflammatory effects and hepatotoxicity of Tripterygium-loaded solid lipid nanoparticles on adjuvant-induced arthritis in rats Phytomedicine 19 2012 998 1006
    • (2012) Phytomedicine , vol.19 , pp. 998-1006
    • Xue, M.1    Jiang, Z.-Z.2    Wu, T.3    Li, J.4    Zhang, L.5    Zhao, Y.6    Li, X.-J.7    Zhang, L.-Y.8    Yang, S.-Y.9
  • 36
    • 73749088747 scopus 로고    scopus 로고
    • Triptolide poisonous side effect-liver hurt and mechanism preliminary study
    • X. Yang, J. Yang, Y. Gao, and C. Wu Triptolide poisonous side effect-liver hurt and mechanism preliminary study Chin. J. Pract. Chin. Modern Med. 19 2006 2832 2833
    • (2006) Chin. J. Pract. Chin. Modern Med. , vol.19 , pp. 2832-2833
    • Yang, X.1    Yang, J.2    Gao, Y.3    Wu, C.4
  • 37
    • 84874433006 scopus 로고    scopus 로고
    • Inhibitory effect of PNS on drug metabolism enzyme CYP3A in rat livers and its kinetic analysis
    • Z. Yang, and X. Yang Inhibitory effect of PNS on drug metabolism enzyme CYP3A in rat livers and its kinetic analysis Zhongguo Zhong Yao Za Zhi 37 2012 3486 3489
    • (2012) Zhongguo Zhong Yao Za Zhi , vol.37 , pp. 3486-3489
    • Yang, Z.1    Yang, X.2
  • 38
    • 73749084404 scopus 로고    scopus 로고
    • Effects of cytochrome P4503A inducer dexamethasone on the metabolism and toxicity of triptolide in rat
    • X. Ye, W. Li, Y. Yan, C. Mao, R. Cai, H. Xu, and X. Yang Effects of cytochrome P4503A inducer dexamethasone on the metabolism and toxicity of triptolide in rat Toxicol. Lett. 192 2010 212 220
    • (2010) Toxicol. Lett. , vol.192 , pp. 212-220
    • Ye, X.1    Li, W.2    Yan, Y.3    Mao, C.4    Cai, R.5    Xu, H.6    Yang, X.7
  • 39
    • 84862324777 scopus 로고    scopus 로고
    • Synergic and attenuated effect of TGP combined with leigongteng on Rheumatoid arthritis
    • L. Zhang, Y.-l Zhou, and W. Liu Synergic and attenuated effect of TGP combined with leigongteng on Rheumatoid arthritis Tianjin J. Tradit. Chin. Med. 3 2005 013
    • (2005) Tianjin J. Tradit. Chin. Med. , vol.3 , pp. 013
    • Zhang, L.1    Zhou, Y.-L.2    Liu, W.3
  • 40
    • 84882245331 scopus 로고    scopus 로고
    • General toxicity of Pinellia ternata (Thunb.) Berit. in rat: A metabonomic method for profiling of serum metabolic changes
    • Z.-H. Zhang, Y.-Y. Zhao, X.-l. Cheng, Z. Dai, C. Zhou, X. Bai, and R.-C. Lin General toxicity of Pinellia ternata (Thunb.) Berit. in rat: a metabonomic method for profiling of serum metabolic changes J. Ethnopharmacol. 149 2013 303 310
    • (2013) J. Ethnopharmacol. , vol.149 , pp. 303-310
    • Zhang, Z.-H.1    Zhao, Y.-Y.2    Cheng, X.-L.3    Dai, Z.4    Zhou, C.5    Bai, X.6    Lin, R.-C.7
  • 41
    • 84861144099 scopus 로고    scopus 로고
    • Triptolide: Structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms
    • Z.-L. Zhou, Y.-X. Yang, J. Ding, Y.-C. Li, and Z.-H. Miao Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms Nat. Prod. Rep. 29 2012 457 475
    • (2012) Nat. Prod. Rep. , vol.29 , pp. 457-475
    • Zhou, Z.-L.1    Yang, Y.-X.2    Ding, J.3    Li, Y.-C.4    Miao, Z.-H.5


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