Comparison of toxic reaction of Tripterygium wilfordii multiglycoside in normal and adjuvant arthritic rats

Journal of Ethnopharmacology

Volumn 135, Issue 2, 2011, Pages 270-277

  Li, Jian ^a,b   Lu, Yongheng ^a   Xiao, Cheng ^c   Lu, Cheng ^a   Niu, Xuyan ^a   He, Xiaojuan ^a   Zhao, Hongyan ^a   Tan, Yong ^a   Lu, Aiping ^a,d  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^d SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Adjuvant arthritis; Rat; Toxicity; Tripterygium wilfordii multiglycoside

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CHENODEOXYCHOLIC ACID; LYSOPHOSPHATIDYLCHOLINE; TRIPTERYGIUM WILFORDII EXTRACT; URSODEOXYCHOLIC ACID;

ACUTE TOXICITY; ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MEGADOSE; LIPID METABOLISM; MALE; NONHUMAN; RAT; RHEUMATOID ARTHRITIS; TOXICITY TESTING; UPREGULATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CHROMATOGRAPHY, LIQUID; GLYCOSIDES; MALE; MASS SPECTROMETRY; RATS; RATS, SPRAGUE-DAWLEY; TRIPTERYGIUM;

ANIMALIA; RATTUS; TRIPTERYGIUM WILFORDII;

EID: 79955685378     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2011.03.007     Document Type: Article

References (23)

1. R. Ambrosio, M.L. Sannino, L. Cortese, C. Nappi, D. Ara, and M. Cioffi Validation and application of an immunofluorimetric assay for detection of serum free triiodothyronine and free thyroxine concentrations in buffalo under various physiological conditions Journal of Veterinary Diagnostic Investigation 21 2009 668 673
2. P.H. Canter, H.S. Lee, and E. Ernst A systermatic review of randomised clinical trials of Tripterygium wilfordii for theumatoid arthritis Phytomedicine 13 2006 371 377 (Pubitemid 44382443)
3. Y. Chen, X.M. Zhang, F.M. Han, P. Du, and Q.S. Xifa Gene expression profile analyses of mice livers injured by Leigongteng World Journal of Gastroenterology 13 2007 3619 3624 (Pubitemid 47162271)
4. M. Chen, Y. Ni, H. Duan, Y. Qiu, C. Guo, Y. Jiao, H. Shi, M. Su, and W. Jia Mass spectrometry-based metabolic profiling of rat urine associated with general toxicity induced by the multiglycoside of Tripterygium wilfordii hook Chemical Research in Toxicology 21 2008 288 294
5. R. Goldbach-Mansky, M. Wilson, R. Fleischmann, N. Olsen, J. Silverfield, P. Kempf, A. Kivitz, Y. Sherrer, F. Pucino, G. Csako, R. Costello, T.H. Pham, C. Snyder, D. van der Heijde, X. Tao, R. Wesley, and P.E. Lipsky Comparison of Tripterygium wilfordii hook F. versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial Annals of Internal Medicine 151 2009 229 240
6. P.N. Huynh, A.P. Hikim, C. Wang, K. Stefonovic, Y.H. Lue, A. Leung, V. Atienza, S. Baravarian, V. Reutrakul, and R.S. Swerdloff Long-term effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats Journal of Andrology 21 2000 689 699
7. Y.H He, J. Zhou, X.F. Chen, Y. Tong, J.C. Tang, A.S. Chan, and A.P. Lu Anti-inflammatory and anti-oxidative effects of cherries on Freund's adjuvant-induced arthritis in rats Scandinavian Journal of Rheumatology 35 2006 356 358 (Pubitemid 44601068)
8. D.P. Jones, J.J. Lemasters, D. Han, U.A. Boelsterli, and N. Kaplowitz Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria Molecular Interventions 10 2010 98 111
9. L. Li, B. Sun, Q. Zhang, J.J. Fang, K. Ma, Y. Li, H. Chen, F. Dong, Y. Gao, F. Li, and X. Yan Metabonomic study on the toxicity of Hei-Shun-Pian, the processed lateral root of Aconitum carmichaelii Debx Journal of Ethnopharmacology 116 2008 561 568 (Pubitemid 351335197)
10. L Liu, Z. Jiang, J. Liu, X. Huang, T. Wang, J. Liu, Y. Zhang, Z. Zhou, J. Guo, L. Yang, Y. Chen, and L. Zhang Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats Toxicology 271 2010 57 63
11. Y. Liu, B. Zhu, and G.M. Guo Retrospective analysis of 178 traditional medicine ADR/ADE reports Chinese Journal of Pharmacovigilance 7 2010 49 51 (in Chinese)
12. T. Matsumoto, T. Kobayashi, and K. Kamata Role of lysophosphatidyl choline (LPC) in atherosclerosis Current Medicinal Chemistry 14 2007 3209 3220
13. J.K. Nicholson Global systems biology, personalized medicine and molecular epidemiology Molecular Systems Biology 2 2006 52
14. J. Nicholson, H. Keun, and T. Ebbels COMET and the challenge of drug safety screening Journal of Proteome Research 6 2007 4098 4099 (Pubitemid 350158488)
15. B. Ni, Z. Jiang, X. Huang, F. Xu, R. Zhang, Z. Zhang, Y. Tian, T. Wang, T. Zhu, J. Liu, and L. Zhang Male reproductive toxicity and toxicokinetics of triptolide in rats Arzneimittel-Forschung 58 2008 673 680
16. D.W. Pyatt, Y. Yang, B. Mehos, A. Le, W. Stillman, and R.D. Irons Hematotoxicity of the Chinese herbal medicine Tripterygium wilfordii hook F. in CD34-positive human bone marrow cells Molecular Pharmacology 57 2000 512 518 (Pubitemid 30140881)
17. C. Schober, J. Schiller, F. Pinker, J.G. Hengstler, and B. Fuchs Lysophosphatidylethanolamine is, in contrast to, choline, generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid Bioorganic Chemistry 37 2009 202 210
18. X. Sun, S.M. Zhang, Ch. Tian, L. Yang, L.M. Wang, and S.L. Li Safety of Tripterygium wilfordii hook F. Chinese Journal of New Drug 10 2001 539 543 (in Chinese)
19. X.L. Tao, J.J. Cush, M. Garret, and P.E. Lipsky A phase I study of ethyl acetate extract of the chinese antirheumatic herb Tripterygium wilfordii hook F. in rheumatoid arthritis The Journal of Rheumatology 28 2001 2160 2167 (Pubitemid 32947856)
20. X. Tao, J. Younger, F.Z. Fan, B. Wang, and P.E. Lipsky Benefit of an extract of Tripterygium wilfordii hook F. in patients with rheumatoid arthritis: a double-blind, placebo-controlled study Arthritis and Rheumatism 46 2002 1735 1743 (Pubitemid 34774504)
21. H. Van Wietmarschen, K. Yuan, C. Lu, P. Gao, J. Wang, C. Xiao, M. Wang, J. Schroën, A. Lu, G. Xu, and J. Van der Greef Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients Journal of Clinical Rheumatology 15 2009 330 337
22. P.Y. Yin, P. Mohemaiti, J. Chen, X.J. Zhao, X. Lu, A. Yimiti, H. Upur, and G. Xu Serum metabolic profiling of abnormal savda by liquid chromatography/mass spectrometry Journal of Chromatography (B) 871 2008 322 327
23. C.X. Zheng, Z.H. Chen, C.H. Zeng, W.S. Qin, L.S. Li, and Z.H. Liu Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro Kidney International 74 2008 596 612