Heat shock protein 72 protects kidney proximal tubule cells from injury induced by triptolide by means of activation of the MEK/ERK pathway

International Journal of Toxicology

Volumn 28, Issue 3, 2009, Pages 177-189

  Wang, Zhipeng ^a   Jin, Haifeng ^b   Li, Chen ^b   Hou, Ying ^b   Mei, Qibing ^b   Fan, Daiming ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

ERK1 2; Heat shock protein 72; MEK; Nephrotoxicity; Triptolide

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; HEAT SHOCK PROTEIN 72; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; RAF PROTEIN; SMALL INTERFERING RNA; TRIPTOLIDE; DITERPENE; EPOXIDE; GLUCOSE; PHENANTHRENE DERIVATIVE; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; PROTEIN ANALYSIS; RAT; RENAL PROTECTION; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE BLOOD LEVEL; HEAT SHOCK RESPONSE; KIDNEY DISEASE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BLOOD GLUCOSE; CELL LINE; CELL SURVIVAL; DITERPENES; EPOXY COMPOUNDS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; HEAT-SHOCK RESPONSE; HSP72 HEAT-SHOCK PROTEINS; HUMANS; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHENANTHRENES; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SODIUM-GLUCOSE TRANSPORTER 1; SODIUM-GLUCOSE TRANSPORTER 2;

EID: 68849095597     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581809337418     Document Type: Article

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