Investigation of the active components in Tripterygium wilfordii leading to its acute hepatotoxicty and nephrotoxicity

Journal of Ethnopharmacology

Volumn 162, Issue , 2015, Pages 238-243

  Li, Xin Xiu ^a   Du, Fu Ying ^a   Liu, Hui Xiang ^a   Ji, Jian Bo ^a   Xing, Jie ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Active components; Hematology; Metabolism; Toxicity; Tripterygium wilfordii

Indexed keywords

ALKALOID DERIVATIVE; EUONINE; GLUTATHIONE; PERITASSINE; TERPENE DERIVATIVE; TRIPTERYGIUM WILFORDII EXTRACT; TRIPTOLIDE; TRIPTONIDE; UNCLASSIFIED DRUG; WILFORGINE; WILFORINE; PLANT EXTRACT;

ACUTE TOXICITY; AEROBIC METABOLISM; ANGELICA SINENSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTRAGALUS MEMBRANACEUS; CONJUGATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DETOXIFICATION; DRUG HYDROLYSIS; DRUG METABOLISM; ELECTROPHILICITY; GLYCYRRHIZA URALENSIS; HYDROLYSIS; HYDROXYLATION; LIQUID CHROMATOGRAPHY; LIVER TOXICITY; MALE; MASS SPECTROMETRY; METABOLIC ACTIVATION; METABOLITE; MOUSE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; TRIPTERYGIUM WILFORDII; ANIMAL; CHEMICAL STRUCTURE; CHEMICALLY INDUCED; CHEMISTRY; KIDNEY DISEASE; METABOLISM; TOXIC HEPATITIS; TRIPTERYGIUM;

MUS; TRIPTERYGIUM WILFORDII;

ANIMALS; DRUG-INDUCED LIVER INJURY; GLUTATHIONE; KIDNEY DISEASES; MICE; MOLECULAR STRUCTURE; PLANT EXTRACTS; TRIPTERYGIUM;

EID: 84921649784     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.01.004     Document Type: Article

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