Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults

Nature Communications

Volumn 7, Issue , 2016, Pages

  Hasegawa, Koichi ^a   Yasuda, Toru ^b,d   Shiraishi, Chinatsu ^a   Fujiwara, Kazushiro ^a   Przedborski, Serge ^c   Mochizuki, Hideki ^b   Yoshikawa, Kazuaki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; MESSENGER RNA; NECDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADULT; BIOLOGICAL PRODUCTION; DEGRADATION; GENE EXPRESSION; INHIBITION; MITOCHONDRION; NEUROLOGY; RODENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN MITOCHONDRION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOPHAGY; MOTOR COORDINATION; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SUBSTANTIA NIGRA; SUBVENTRICULAR ZONE; WESTERN BLOTTING; ANIMAL; BRAIN CORTEX; CYTOLOGY; DISEASE MODEL; GENETICS; HEK293 CELL LINE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; NERVE CELL; ORGANELLE BIOGENESIS; PARKINSON DISEASE; PARKINSONISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MAMMALIA; MUS;

ANIMALS; BLOTTING, WESTERN; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; DOPAMINERGIC NEURONS; GENE EXPRESSION; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; ORGANELLE BIOGENESIS; PARKINSON DISEASE; PARKINSONIAN DISORDERS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; PROTEIN STABILITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; TRANSCRIPTION FACTORS;

EID: 84961839432     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10943     Document Type: Article

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