Necdin promotes tangential migration of neocortical interneurons from basal forebrain

Journal of Neuroscience

Volumn 30, Issue 10, 2010, Pages 3709-3714

  Kuwajima, Takaaki ^a,b   Hasegawa, Koichi ^a   Yoshikawa, Kazuaki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; NECDIN; NUCLEIC ACID BINDING PROTEIN; PROTEIN DLX2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL MIGRATION; FOREBRAIN; GENE CONTROL; IMMUNOHISTOCHEMISTRY; INTERNEURON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; CELL MOVEMENT; EVOLUTION, MOLECULAR; FEMALE; INTERNEURONS; MALE; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NEOCORTEX; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; ORGAN CULTURE TECHNIQUES; PROSENCEPHALON;

EID: 77949342623     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5797-09.2010     Document Type: Article

References (29)

1. Anderson SA, Qiu M, Bulfone A, Eisenstat DD, Meneses J, Pedersen R, Rubenstein JL (1997a) Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. Neuron 19:27-37.
2. Anderson SA, Eisenstat DD, Shi L, Rubenstein JL (1997b) Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 278:474-476.
3. Barker PA, Salehi A (2002) The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease. J Neurosci Res 67:705-712.
4. Colasante G, Collombat P, Raimondi V, Bonanomi D, Ferrai C, Maira M, Yoshikawa K, Mansouri A, Valtorta F, Rubenstein JL, Broccoli V (2008) Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons. J Neurosci 28:10674 -10686.
5. de Melo J, Zhou QP, Zhang Q, Zhang S, Fonseca M, Wigle JT, Eisenstat DD (2008) Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res 36:872- 884.
6. Descheemaeker MJ, Govers V, Vermeulen P, Fryns JP (2006) Pervasive developmental disorders in Prader-Willi syndrome: the Leuven experience in 59 subjects and controls. Am J Med Genet A 140:1136 -1142.
7. Fan Z, Greenwood R, Fisher A, Pendyal S, PowellCM (2009) Characteristics and frequency of seizure disorder in 56 patients with Prader-Willi syndrome. Am J Med Genet A 149A:1581-1584.
8. Gelman DM, Martini FJ, Nobrega-Pereira S, Pierani A, Kessaris N, Marin O (2009) The embryonic preoptic area is a novel source of cortical GABAergic interneurons. J Neurosci 29:9380 -9389.
9. Gerard M, Hernandez L, Wevrick R, Stewart CL (1999) Disruption of the mouse necdin gene results in early post-natal lethality. Nat Genet 23:199 -202.
10. Givens ML, Rave-Harel N, Goonewardena VD, Kurotani R, Berdy SE, Swan CH, Rubenstein JL, Robert B, Mellon PL (2005) Developmental regulation of gonadotropin-releasing hormone gene expression by theMSXand DLX homeodomain protein families. J Biol Chem 280:19156 -19165.
11. Hasegawa K, Yoshikawa K (2008) Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J Neurosci 28:8772- 8784.
12. Jay P, Rougeulle C, Massacrier A, Moncla A, Mattei MG, Malzac P, Roeckel N, Taviaux S, Lefranc JL, Cau P, Berta P, Lalande M, Muscatelli F (1997) The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region. Nat Genet 17:357-361.
13. Kuwajima T, Taniura H, Nishimura I, Yoshikawa K (2004) Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells. J Biol Chem 279:40484-40493.
14. Kuwajima T, Nishimura I, Yoshikawa K (2006) Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins. J Neurosci 26:5383-5392.
15. Kuwako K, Hosokawa A, Nishimura I, Uetsuki T, Yamada M, Nada S, Okada M, Yoshikawa K (2005) Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival. J Neurosci 25:7090-7099.
16. Lopez-Sanchez N, Gonzalez-Fernandez Z, Niinobe M, Yoshikawa K, Frade JM (2007) Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins. Physiol Genomics 30:156 -171.
17. MacDonald HR, Wevrick R (1997) The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouse. Hum Mol Genet 6:1873-1878.
18. Marin O, Rubenstein JL (2003) Cell migration in the forebrain. Annu Rev Neurosci 26:441- 483.
19. Maruyama K, Usami M, Aizawa T, Yoshikawa K (1991) A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells. Biochem Biophys Res Commun 178:291-296.
20. Miller NL, Wevrick R, Mellon PL (2009) Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development. Hum Mol Genet 18:248 -260.
21. Muscatelli F, Abrous DN, Massacrier A, Boccaccio I, Le Moal M, Cau P, CremerH (2000) Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome. Hum Mol Genet 9:3101-3110.
22. Nakada Y, Taniura H, Uetsuki T, Inazawa J, Yoshikawa K (1998) The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion region. Gene 213:65-72.
23. Niinobe M, Koyama K, Yoshikawa K (2000) Cellular and subcellular localization of necdin in fetal and adult mouse brain. Dev Neurosci 22:310 -319.
24. Polleux F, Whitford KL, Dijkhuizen PA, Vitalis T, Ghosh A (2002) Control of cortical interneuron migration by neurotrophins and PI3-kinase signaling. Development 129:3147-3160.
25. Rapkins RW, Hore T, Smithwick M, Ager E, Pask AJ, Renfree MB, Kohn M, Hameister H, Nicholls RD, Deakin JE, Graves JA (2006) Recent assembly of an imprinted domain from non-imprinted components. PLoS Genet 2:e182.
26. Rubenstein JL, Merzenich MM (2003) Model of autism: increased ratio of excitation/inhibition in key neural systems. Genes Brain Behav 2:255-267.
27. Tennese AA, Gee CB, Wevrick R (2008) Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons. Dev Dyn 237:1935-1943.
28. Tornberg J, Voikar V, Savilahti H, Rauvala H, Airaksinen MS (2005) Behavioural phenotypes of hypomorphic KCC2-deficient mice. Eur J Neurosci 21:1327-1337.
29. Uetsuki T, Takagi K, Sugiura H, Yoshikawa K (1996) Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter. J Biol Chem 271:918 -924.