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Volumn 7, Issue , 2016, Pages

Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS AND CELL COMPONENTS; NERVOUS SYSTEM; POLYMER; REPLACEMENT; RODENT; THREE-DIMENSIONAL MODELING; TRANSPLANTATION;

EID: 84961789188     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10862     Document Type: Article
Times cited : (107)

References (48)
  • 1
    • 84355166561 scopus 로고    scopus 로고
    • Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
    • Kriks, S. et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480, 547-551 (2011).
    • (2011) Nature , vol.480 , pp. 547-551
    • Kriks, S.1
  • 2
    • 84924196102 scopus 로고    scopus 로고
    • Therapeutic effects of human multilineage-differentiating stress enduring (MUSE) cell transplantation into infarct brain of mice
    • Yamauchi, T. et al. Therapeutic effects of human multilineage-differentiating stress enduring (MUSE) cell transplantation into infarct brain of mice. PLoS ONE 10, e0116009 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0116009
    • Yamauchi, T.1
  • 3
    • 79955823644 scopus 로고    scopus 로고
    • Achieving stable human stem cell engraftment and survival in the CNS: Is the future of regenerative medicine immunodeficient?
    • Anderson, A. J. et al. Achieving stable human stem cell engraftment and survival in the CNS: is the future of regenerative medicine immunodeficient? Regen. Med. 6, 367-406 (2011).
    • (2011) Regen. Med. , vol.6 , pp. 367-406
    • Anderson, A.J.1
  • 4
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos, J. T. et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321, 1218-1221 (2008).
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1
  • 5
    • 79952172335 scopus 로고    scopus 로고
    • LRRK2 mutant iPSC-derived da neurons demonstrate increased susceptibility to oxidative stress
    • Nguyen, H. N. et al. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 8, 267-280 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 267-280
    • Nguyen, H.N.1
  • 6
    • 84871840585 scopus 로고    scopus 로고
    • Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons
    • Tran, N. N., Ladran, I. G., Brennand, K. J. Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons. Schizophr. Bull. 39, 4-10 (2013).
    • (2013) Schizophr. Bull. , vol.39 , pp. 4-10
    • Tran, N.N.1    Ladran, I.G.2    Brennand, K.J.3
  • 7
    • 84866436991 scopus 로고    scopus 로고
    • Human pluripotent stem cells: Applications and challenges in neurological diseases
    • Hibaoui, Y., Feki, A. Human pluripotent stem cells: applications and challenges in neurological diseases. Front. Physiol. 3, 267 (2012).
    • (2012) Front. Physiol. , vol.3 , pp. 267
    • Hibaoui, Y.1    Feki, A.2
  • 8
    • 79952579500 scopus 로고    scopus 로고
    • Stem cells and stroke: Opportunities, challenges and strategies
    • Burns, T. C., Steinberg, G. K. Stem cells and stroke: opportunities, challenges and strategies. Expert. Opin. Biol. Ther. 11, 447-461 (2011).
    • (2011) Expert. Opin. Biol. Ther. , vol.11 , pp. 447-461
    • Burns, T.C.1    Steinberg, G.K.2
  • 9
    • 84862158944 scopus 로고    scopus 로고
    • Ectopic expression of neurogenin 2 alone is sufficient to induce differentiation of embryonic stem cells into mature neurons
    • Thoma, E. C. et al. Ectopic expression of neurogenin 2 alone is sufficient to induce differentiation of embryonic stem cells into mature neurons. PLoS ONE 7, e38651 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e38651
    • Thoma, E.C.1
  • 10
    • 84878849645 scopus 로고    scopus 로고
    • Rapid single-step induction of functional neurons from human pluripotent stem cells
    • Zhang, Y. et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 78, 785-798 (2013).
    • (2013) Neuron , vol.78 , pp. 785-798
    • Zhang, Y.1
  • 11
    • 84924219718 scopus 로고    scopus 로고
    • Generation of induced neuronal cells by the single reprogramming factor ASCL1
    • Chanda, S. et al. Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Rep. 3, 282-296 (2014).
    • (2014) Stem Cell Rep. , vol.3 , pp. 282-296
    • Chanda, S.1
  • 12
    • 79960854285 scopus 로고    scopus 로고
    • Induction of human neuronal cells by defined transcription factors
    • Pang, Z. P. et al. Induction of human neuronal cells by defined transcription factors. Nature 476, 220-223 (2011).
    • (2011) Nature , vol.476 , pp. 220-223
    • Pang, Z.P.1
  • 13
    • 84933671977 scopus 로고    scopus 로고
    • Human induced pluripotent stem cell-derived neurons improve motor asymmetry in a 6-hydroxydopamine-induced rat model of Parkinson's disease
    • Han, F. et al. Human induced pluripotent stem cell-derived neurons improve motor asymmetry in a 6-hydroxydopamine-induced rat model of Parkinson's disease. Cytotherapy 17, 665-679 (2015).
    • (2015) Cytotherapy , vol.17 , pp. 665-679
    • Han, F.1
  • 14
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman, E., Pankov, R., Stevens, D. R., Yamada, K. M. Taking cell-matrix adhesions to the third dimension. Science 294, 1708-1712 (2001).
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 15
    • 61449181308 scopus 로고    scopus 로고
    • One-dimensional topography underlies three-dimensional fibrillar cell migration
    • Doyle, A. D., Wang, F. W., Matsumoto, K., Yamada, K. M. One-dimensional topography underlies three-dimensional fibrillar cell migration. J. Cell Biol. 184, 481-490 (2009).
    • (2009) J. Cell Biol. , vol.184 , pp. 481-490
    • Doyle, A.D.1    Wang, F.W.2    Matsumoto, K.3    Yamada, K.M.4
  • 17
    • 34247213463 scopus 로고    scopus 로고
    • Interaction of embryonic cortical neurons on nanofibrous scaffolds for neural tissue engineering
    • Nisbet, D. R. et al. Interaction of embryonic cortical neurons on nanofibrous scaffolds for neural tissue engineering. J. Neural. Eng. 4, 35-41 (2007).
    • (2007) J. Neural. Eng. , vol.4 , pp. 35-41
    • Nisbet, D.R.1
  • 18
    • 77954421695 scopus 로고    scopus 로고
    • Accelerated neuritogenesis and maturation of primary spinal motor neurons in response to nanofibers
    • Gertz, C. C. et al. Accelerated neuritogenesis and maturation of primary spinal motor neurons in response to nanofibers. Dev. Neurobiol. 70, 589-603 (2010).
    • (2010) Dev. Neurobiol. , vol.70 , pp. 589-603
    • Gertz, C.C.1
  • 19
    • 84871507237 scopus 로고    scopus 로고
    • Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering
    • Cheng, T. Y., Chen, M. H., Chang, W. H., Huang, M. Y., Wang, T. W. Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering. Biomaterials 34, 2005-2016 (2013).
    • (2013) Biomaterials , vol.34 , pp. 2005-2016
    • Cheng, T.Y.1    Chen, M.H.2    Chang, W.H.3    Huang, M.Y.4    Wang, T.W.5
  • 20
    • 84864970897 scopus 로고    scopus 로고
    • Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles
    • Bible, E. et al. Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles. Biomaterials 33, 7435-7446 (2012).
    • (2012) Biomaterials , vol.33 , pp. 7435-7446
    • Bible, E.1
  • 21
    • 76149124841 scopus 로고    scopus 로고
    • Effect of biodegradable fibrin scaffold on survival, migration, and differentiation of transplanted bone marrow stromal cells after cortical injury in rats
    • Yasuda, H. et al. Effect of biodegradable fibrin scaffold on survival, migration, and differentiation of transplanted bone marrow stromal cells after cortical injury in rats. J. Neurosurg. 112, 336-344 (2010).
    • (2010) J. Neurosurg. , vol.112 , pp. 336-344
    • Yasuda, H.1
  • 22
    • 84896776947 scopus 로고    scopus 로고
    • Accelerating proliferation of neural stem/progenitor cells in collagen sponges immobilized with engineered basic fibroblast growth factor for nervous system tissue engineering
    • Ma, F. et al. Accelerating proliferation of neural stem/progenitor cells in collagen sponges immobilized with engineered basic fibroblast growth factor for nervous system tissue engineering. Biomacromolecules 15, 1062-1068 (2014).
    • (2014) Biomacromolecules , vol.15 , pp. 1062-1068
    • Ma, F.1
  • 23
    • 84859871858 scopus 로고    scopus 로고
    • Culture of neonatal rodent microglia, astrocytes, and oligodendrocytes from cortex and spinal cord
    • Skaper, S. D., Argentini, C., Barbierato, M. Culture of neonatal rodent microglia, astrocytes, and oligodendrocytes from cortex and spinal cord. Methods Mol. Biol. 846, 67-77 (2012).
    • (2012) Methods Mol. Biol. , vol.846 , pp. 67-77
    • Skaper, S.D.1    Argentini, C.2    Barbierato, M.3
  • 24
    • 84864762783 scopus 로고    scopus 로고
    • Microfibrous substrate geometry as a critical trigger for organization, self-renewal, and differentiation of human embryonic stem cells within synthetic 3-dimensional microenvironments
    • Carlson, A. L. et al. Microfibrous substrate geometry as a critical trigger for organization, self-renewal, and differentiation of human embryonic stem cells within synthetic 3-dimensional microenvironments. FASEB J 26, 3240-3251 (2012).
    • (2012) FASEB J , vol.26 , pp. 3240-3251
    • Carlson, A.L.1
  • 25
    • 0037466351 scopus 로고    scopus 로고
    • Polymers derived from the amino acid-tyrosine: Polycarbonates, polyarylates and copolymers with poly(ethylene glycol)
    • Bourke, S. L., Kohn, J. Polymers derived from the amino acid-tyrosine: polycarbonates, polyarylates and copolymers with poly(ethylene glycol). Adv. Drug. Deliv. Rev. 55, 447-466 (2003).
    • (2003) Adv. Drug. Deliv. Rev. , vol.55 , pp. 447-466
    • Bourke, S.L.1    Kohn, J.2
  • 26
    • 0032487114 scopus 로고    scopus 로고
    • Comparative histological evaluation of new tyrosine-derived polymers and poly (L-lactic acid) as a function of polymer degradation
    • Hooper, K. A., Macon, N. D., Kohn, J. Comparative histological evaluation of new tyrosine-derived polymers and poly (L-lactic acid) as a function of polymer degradation. J. Biomed. Mater. Res. 41, 443-454 (1998).
    • (1998) J. Biomed. Mater. Res. , vol.41 , pp. 443-454
    • Hooper, K.A.1    MacOn, N.D.2    Kohn, J.3
  • 27
    • 56449118229 scopus 로고    scopus 로고
    • The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation
    • Christopherson, G. T., Song, H., Mao, H.-Q. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials 30, 556-564 (2009).
    • (2009) Biomaterials , vol.30 , pp. 556-564
    • Christopherson, G.T.1    Song, H.2    Mao, H.-Q.3
  • 28
    • 84873282055 scopus 로고    scopus 로고
    • Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo
    • Espuny-Camacho, I. et al. Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron 77, 440-456 (2013).
    • (2013) Neuron , vol.77 , pp. 440-456
    • Espuny-Camacho, I.1
  • 29
    • 84908232279 scopus 로고    scopus 로고
    • Engineered N-cadherin and L1 biomimetic substrates concertedly promote neuronal differentiation, neurite extension and neuroprotection of human neural stem cells
    • Cherry, J. F., Bennett, N. K., Schachner, M., Moghe, P. V. Engineered N-cadherin and L1 biomimetic substrates concertedly promote neuronal differentiation, neurite extension and neuroprotection of human neural stem cells. Acta. Biomater. 10, 4113-4126 (2014).
    • (2014) Acta. Biomater. , vol.10 , pp. 4113-4126
    • Cherry, J.F.1    Bennett, N.K.2    Schachner, M.3    Moghe, P.V.4
  • 30
    • 84931563115 scopus 로고    scopus 로고
    • Carbon nanotube composites as multifunctional substrates for in situ actuation of differentiation of human neural stem cells
    • Landers, J. et al. Carbon nanotube composites as multifunctional substrates for in situ actuation of differentiation of human neural stem cells. Adv. Healthc. Mater. 3, 1745-1752 (2014).
    • (2014) Adv. Healthc. Mater. , vol.3 , pp. 1745-1752
    • Landers, J.1
  • 31
    • 84864091160 scopus 로고    scopus 로고
    • Oriented, multimeric biointerfaces of the L1 cell adhesion molecule: An approach to enhance neuronal and neural stem cell functions on 2-D and 3-D polymer substrates
    • Cherry, J. F. et al. Oriented, multimeric biointerfaces of the L1 cell adhesion molecule: an approach to enhance neuronal and neural stem cell functions on 2-D and 3-D polymer substrates. Biointerphases 7, 22 (2012).
    • (2012) Biointerphases , vol.7 , pp. 22
    • Cherry, J.F.1
  • 32
    • 33747860195 scopus 로고    scopus 로고
    • N-cadherin signaling in synapse formation and neuronal physiology
    • Bruses, J. L. N-cadherin signaling in synapse formation and neuronal physiology. Mol. Neurobiol. 33, 237-252 (2006).
    • (2006) Mol. Neurobiol. , vol.33 , pp. 237-252
    • Bruses, J.L.1
  • 33
    • 77953106906 scopus 로고    scopus 로고
    • N-cadherin-dependent neuron-neuron interaction is required for the maintenance of activity-induced dendrite growth
    • Tan, Z. J., Peng, Y., Song, H. L., Zheng, J. J., Yu, X. N-cadherin-dependent neuron-neuron interaction is required for the maintenance of activity-induced dendrite growth. Proc. Natl Acad. Sci. USA 107, 9873-9878 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 9873-9878
    • Tan, Z.J.1    Peng, Y.2    Song, H.L.3    Zheng, J.J.4    Yu, X.5
  • 34
    • 10044281490 scopus 로고    scopus 로고
    • N-cadherin juxtamembrane domain modulates voltage-gated Ca2\+ current via RhoA GTPase and Rho-associated kinase
    • Piccoli, G., Rutishauser, U., Bruses, J. L. N-cadherin juxtamembrane domain modulates voltage-gated Ca2\+ current via RhoA GTPase and Rho-associated kinase. J. Neurosci. 24, 10918-10923 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 10918-10923
    • Piccoli, G.1    Rutishauser, U.2    Bruses, J.L.3
  • 35
    • 34250206996 scopus 로고    scopus 로고
    • A ROCK inhibitor permits survival of dissociated human embryonic stem cells
    • Watanabe, K. et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotech. 25, 681-686 (2007).
    • (2007) Nat. Biotech. , vol.25 , pp. 681-686
    • Watanabe, K.1
  • 36
    • 77952360137 scopus 로고    scopus 로고
    • Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules
    • Xu, Y. et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc. Natl Acad. Sci. USA 107, 8129-8134 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 8129-8134
    • Xu, Y.1
  • 37
    • 77952991347 scopus 로고    scopus 로고
    • Individual cell movement, asymmetric colony expansion, rho-associated kinase, and E-cadherin impact the clonogenicity of human embryonic stem cells
    • Li, L. et al. Individual cell movement, asymmetric colony expansion, rho-associated kinase, and E-cadherin impact the clonogenicity of human embryonic stem cells. Biophys. J. 98, 2442-2451 (2010).
    • (2010) Biophys. J. , vol.98 , pp. 2442-2451
    • Li, L.1
  • 38
    • 0042123790 scopus 로고    scopus 로고
    • Interference with anoikis-induced cell death of dopamine neurons: Implications for augmenting embryonic graft survival in a rat model of Parkinson's disease
    • Marchionini, D. M. et al. Interference with anoikis-induced cell death of dopamine neurons: implications for augmenting embryonic graft survival in a rat model of Parkinson's disease. J. Comp. Neurol. 464, 172-179 (2003).
    • (2003) J. Comp. Neurol. , vol.464 , pp. 172-179
    • Marchionini, D.M.1
  • 40
    • 0035871386 scopus 로고    scopus 로고
    • Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration
    • Kirik, D., Winkler, C., Bjorklund, A. Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration. J. Neurosci. 21, 2889-2896 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 2889-2896
    • Kirik, D.1    Winkler, C.2    Bjorklund, A.3
  • 41
    • 65849389930 scopus 로고    scopus 로고
    • Microtransplantation of dopaminergic cell suspensions: Further characterization and optimization of grafting parameters
    • Nikkhah, G. et al. Microtransplantation of dopaminergic cell suspensions: further characterization and optimization of grafting parameters. Cell Transplant. 18, 119-133 (2009).
    • (2009) Cell Transplant. , vol.18 , pp. 119-133
    • Nikkhah, G.1
  • 42
    • 0034307725 scopus 로고    scopus 로고
    • Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
    • Studer, L. et al. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J. Neurosci. 20, 7377-7383 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 7377-7383
    • Studer, L.1
  • 43
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer, L., Tabar, V., McKay, R. D. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat. Neurosci. 1, 290-295 (1998).
    • (1998) Nat. Neurosci. , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.3
  • 44
    • 42649130264 scopus 로고    scopus 로고
    • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
    • Wernig, M. et al. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc. Natl Acad. Sci. USA 105, 5856-5861 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 5856-5861
    • Wernig, M.1
  • 45
    • 77649162059 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to functional neurons by defined factors
    • Vierbuchen, T. et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041 (2010).
    • (2010) Nature , vol.463 , pp. 1035-1041
    • Vierbuchen, T.1
  • 46
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1
  • 47
    • 76249131225 scopus 로고    scopus 로고
    • Cytoskeleton-based forecasting of stem cell lineage fates
    • Treiser, M. D. et al. Cytoskeleton-based forecasting of stem cell lineage fates. Proc. Natl Acad. Sci. USA 107, 610-615 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.107 , pp. 610-615
    • Treiser, M.D.1
  • 48
    • 78650049551 scopus 로고    scopus 로고
    • Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression
    • Citri, A. et al. Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. J. Neurosci. 30, 16437-16452 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 16437-16452
    • Citri, A.1


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