Achieving stable human stem cell engraftment and survival in the CNS: Is the future of regenerative medicine immunodeficient?

Regenerative Medicine

Volumn 6, Issue 3, 2011, Pages 367-406

  Anderson, Aileen J ^a,b   Haus, Daniel L ^a   Hooshmand, Mitra J ^a   Perez, Harvey ^a,c   Sontag, Christopher J ^a   Cummings, Brian J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

clinical translation; engraftment; human stem cells; immunodeficient; mmunosuppression; neurological disease; neurotrauma; regenerative medicine; stereology; transplantation; xenograft

Indexed keywords

CYCLOSPORIN A; TACROLIMUS;

ADAPTIVE IMMUNITY; ALLOGENEIC REJECTION; ANTIGEN PRESENTING CELL; BIOLOGICAL ACTIVITY; BRAIN CONTUSION; CELL DIFFERENTIATION; CELL POPULATION; CELL RENEWAL; CENTRAL NERVOUS SYSTEM DISEASE; DOSAGE SCHEDULE COMPARISON; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG MECHANISM; ENGRAFTMENT; GRAFT FAILURE; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; IMMUNE DEFICIENCY; IMMUNOCOMPETENT CELL; IMMUNOPATHOGENESIS; IMMUNOSUPPRESSIVE TREATMENT; MAJOR HISTOCOMPATIBILITY COMPLEX; MIDDLE CEREBRAL ARTERY OCCLUSION; NEURAL STEM CELL; NONHUMAN; OLFACTORY ENSHEATHING CELL; PARKINSON DISEASE; PATIENT SAFETY; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; SPINAL CORD INJURY; STEM CELL TRANSPLANTATION; STROKE; SURVIVAL TIME; TRAUMATIC BRAIN INJURY; TREATMENT RESPONSE; XENOGENEIC REJECTION; XENOTRANSPLANTATION;

ANIMALS; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; GRAFT REJECTION; GRAFT SURVIVAL; HEMATOPOIESIS; HUMANS; NERVOUS SYSTEM DISEASES; REGENERATIVE MEDICINE; STEM CELL TRANSPLANTATION; STEM CELLS; TRANSPLANTATION, HETEROLOGOUS;

EID: 79955823644     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.11.22     Document Type: Review

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