N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase

Journal of Neuroscience

Volumn 24, Issue 48, 2004, Pages 10918-10923

  Piccoli, Giuseppe ^a   Rutishauser, Urs ^a   Brusés, Juan L ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cell adhesion; Ciliary ganglion neuron; N cadherin; RhoA GTPase; ROCK; Voltage activated calcium channel

Indexed keywords

ACTIN; GUANOSINE TRIPHOSPHATASE; MYOSIN; NERVE CELL ADHESION MOLECULE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VOLTAGE GATED CALCIUM CHANNEL;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHICKEN; CONTROLLED STUDY; CYTOSKELETON; EMBRYO; ENZYME INHIBITION; MEMBRANE CURRENT; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION;

ADP RIBOSE TRANSFERASES; AMIDES; ANIMALS; BOTULINUM TOXINS; CADHERINS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL ADHESION; CHICK EMBRYO; CHICKENS; GANGLIA, PARASYMPATHETIC; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ION CHANNEL GATING; ION TRANSPORT; NEURONS; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RECOMBINANT FUSION PROTEINS; RHOA GTP-BINDING PROTEIN;

EID: 10044281490     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4020-04.2004     Document Type: Article

References (34)

1. Aktories K, Weller U, Chhatwal GS (1987) Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin. FEBS Lett 212:109-113.
2. Araano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, Kaibuchi K (1996) Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 271:20246-20249.
3. Anastasiadis PZ, Reynolds AB (2000) The p120 catenin family: complex roles in adhesion, signaling and cancer. J Cell Sci 113:1319-1334.
4. Anastasiadis PZ, Moon SY, Thoreson MA, Mariner DJ, Crawford HC, Zheng Y, Reynolds AB (2000) Inhibition of RhoA by p120 catenin. Nat Cell Biol 2:637-644.
5. Baki L, Marambaud P, Efthimiopoulos S, Georgakopoulos A, Wen P, Cui W, Shioi J, Koo E, Ozawa M, Friedrich Jr VL, Robakis NK (2001) Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. Proc Natl Acad Sci USA 98:2381-2386.
6. Bamji SX, Shimazu K, Kimes N, Huelsken J, Birchmeier W, Lu B, Reichardt LF (2003) Role of beta-catenin in synaptic vesicle localization and pre-synaptic assembly. Neuron 40:719-731.
7. Bozdagi O, Shan W, Tanaka H, Benson DL, Huntley GW (2000) Increasing numbers of synaptic puncta during late-phase LTP: N-cadherin is synthesized, recruited to synaptic sites, and required for potentiation. Neuron 28:245-259.
8. Brusés JL (2000) Cadherin-mediated adhesion at the interneuronal synapse. Curr Opin Cell Biol 12:593-597.
9. Catterall WA (1995) Structure and function of voltage-gated ion channels. Annu Rev Biochem 64:493-531.
10. 2+ channels. Annu Rev Cell Dev Biol 16:521-555.
11. Dolphin AC (1998) Mechanisms of modulation of voltage-dependent calcium channels by G proteins. J Physiol (Lond) 506:3-11.
12. Fannon AM, Colman DR (1996) A model for central synaptic functional complex formation based on the differential adhesive specificities of the cadherins. Neuron 17:423-434.
13. Fujita Y, Krause G, Scheffner M, Zechner D, Leddy HE, Behrens J, Sommer T, Birchmeier W (2002) Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol 4:222-231.
14. Gumbiner BM (2000) Regulation of cadherin adhesive activity. J Cell Biol 148:399-404.
15. Hamburger VHH (1951) A series of normal stages in the development of the chick embryo. J Morphol 88:49-93.
16. Hatta K, Nose A, Nagafuchi A, Takeichi M (1988) Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene family. J Cell Biol 106:873-881.
17. Hille B (1994) Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci 17:531-536.
18. Hirose M, Ishizaki T, Watanabe N, Uehata M, Kranenburg O, Moolenaar WH, Matsumura F, Maekawa M, Bito H, Narumiya S (1998) Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol 141:1625-1636.
19. Neely A, Wei X, Olcese R, Birnbaumer L, Stefani E (1993) Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel. Science 262:575-578.
20. Noren NK, Liu BP, Burridge K, Kreft B (2000) p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol 150:567-580.
21. 2+ currents via cofilin-activated depolymerization of F-actin in guinea-pig cardiomyocytes. J Physiol (Lond) 537:363-370.
22. 2+ current enhancement by alpha 2/delta and beta subunits in Xenopus oocytes: contribution of changes in channel gating and alpha 1 protein level. J Physiol (Lond) 489:55-62.
23. Spafford JD, Zamponi GW (2003) Functional interactions between presynaptic calcium channels and the neurotransmitter release machinery. Curr Opin Neurobiol 13:308-314.
24. Takeichi M (1990) Cadherins: a molecular family important in selective cell-cell adhesion. Annu Rev Biochem 59:237-252.
25. Tanaka H, Shan W, Phillips GR, Arndt K, Bozdagi O, Shapiro L, Huntley GW, Benson DL, Colman DR (2000) Molecular modification of N-cadherin in response to synaptic activity. Neuron 25:93-107.
26. Togashi H, Abe K, Mizoguchi A, Takaoka K, Chisaka O, Takeichi M (2002) Cadherin regulates dendritic spine morphogenesis. Neuron 35:77-89.
27. Uchida N, Honjo Y, Johnson KR, Wheelock MJ, Takeichi M (1996) The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones. J Cell Biol 135:767-779.
28. Ward Y, Spinelli B, Quon MJ, Chen H, Ikeda SR, Kelly K (2004) Phosphorylation of critical serine residues in Gem separates cytoskeletal reorganization from down-regulation of calcium channel activity. Mol Cell Biol 24:651-661.
29. West AE, Griffith EC, Greenberg ME (2002) Regulation of transcription factors by neuronal activity. Nat Rev Neurosci 3:921-931.
30. White MG, Crumling MA, Meriney SD (1997) Developmental changes in calcium current pharmacology and somatostatin inhibition in chick parasympathetic neurons. J Neurosci 17:6302-6313.
31. Wilk-Blaszczak MA, Singer WD, Quill T, Miller B, Frost JA, Sternweis PC, Belardetti F (1997) The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin. J Neurosci 17:4094-4100.
32. Yamaguchi H, Hara M, Strobeck M, Fukasawa K, Schwartz A, Varadi G (1998) Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit. J Biol Chem 273:19348-19356.
33. Yap AS, Brieher WM, Gumbiner BM (1997) Molecular and functional analysis of cadherin-based adherens junctions. Annu Rev Cell Dev Biol 13:119-146.
34. Yap AS, Niessen CM, Gumbiner BM (1998) The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J Cell Biol 141:779-789.