HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1

PLoS Pathogens

Volumn 10, Issue 4, 2014, Pages

  Peng, Yanyan ^a   Xu, Ruidan ^a   Zheng, Xiaofeng ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA INTERFERON; HSCARG PROTEIN; I KAPPA B KINASE EPSILON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; OTUB1 PROTEIN; PEPTIDES AND PROTEINS; RETINOIC ACID INDUCIBLE PROTEIN I LIKE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; I KAPPA B KINASE; NMRAL1 PROTEIN, HUMAN; OTUBAIN 1 PROTEIN, HUMAN; TRAF3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; VIRUS RNA;

AMINO ACID SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INNATE IMMUNITY; MUTANT; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; PHOSPHORYLATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; GENE SILENCING; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; RNA VIRUS; RNA VIRUS INFECTION; TUMOR CELL LINE;

CELL LINE, TUMOR; CYSTEINE ENDOPEPTIDASES; DEAD-BOX RNA HELICASES; GENE KNOCKDOWN TECHNIQUES; HUMANS; I-KAPPA B KINASE; IMMUNITY, INNATE; RNA VIRUS INFECTIONS; RNA VIRUSES; RNA, VIRAL; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 3; TRANSCRIPTION FACTORS; UBIQUITINATION;

EID: 84901301160     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004041     Document Type: Article

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