Fluorescence lifetime imaging of endogenous biomarker of oxidative stress

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Datta, Rupsa ^a   Alfonso Garciá, Alba ^a   Cinco, Rachel ^b   Gratton, Enrico ^a  

^a University of California at Irvine   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; OLEIC ACID; REACTIVE OXYGEN METABOLITE;

CARDIOVASCULAR DISEASE; CHEMISTRY; DIABETES MELLITUS; DRUG EFFECTS; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; HELA CELL LINE; HUMAN; METABOLISM; NEOPLASM; OXIDATIVE STRESS; PATHOLOGY; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; BIOMARKERS; CARDIOVASCULAR DISEASES; DIABETES MELLITUS; HELA CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; NEOPLASMS; OLEIC ACID; OPTICAL IMAGING; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84930212923     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep09848     Document Type: Article

References (34)

1. D'Autreaúx, B. & Toledano, M. B. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat. Rev. Mol. Cell Biol. 8, 813-24 (2007).
2. Finkel, T. Signal transduction by reactive oxygen species. J. Cell Biol. 194, 7-15 (2011).
3. Dröge, W. Free radicals in the physiological control of cell function. Physiol. Rev. 82, 47-95 (2002).
4. Maritim, a C., Sanders, R. a & Watkins, J. B. Diabetes, oxidative stress, and antioxidants: a review. J. Biochem. Mol. Toxicol. 17, 24-38 (2003).
5. Furukawa, S. et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114, 1752-61 (2004).
6. Matsuzawa-Nagata, N. et al. Increased oxidative stress precedes the onset of highfat diet-induced insulin resistance and obesity. Metabolism. 57, 1071-7 (2008).
7. Reuter, S., Gupta, S. C., Chaturvedi, M. M. & Aggarwal, B. B. Oxidative stress, inflammation, and cancer: how are they linked? Free Radic. Biol. Med. 49, 1603-16 (2010).
8. Dhalla, N. S., Temsah, R. M. & Netticadan, T. Role of oxidative stress in cardiovascular diseases. J. Hypertens. 18, 655-73 (2000).
9. Park, H. S., Kim, S. R. & Lee, Y. C. Impact of oxidative stress on lung diseases. Respirology 14, 27-38 (2009).
10. Uttara, B., Singh, A. V, Zamboni, P. & Mahajan, R. T. Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr. Neuropharmacol. 7, 65-74 (2009).
11. Stringari, C., Sierra, R., Donovan, P. J. & Gratton, E. Label-free separation of human embryonic stem cells and their differentiating progenies by phasor fluorescence lifetime microscopy. J. Biomed. Opt. 17, 046012 (2012).
12. Stringari, C. et al. Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue. Proc. Natl. Acad. Sci. U. S. A. 108, 13582-7 (2011).
13. Skala, M. C. et al. In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia. Proc. Natl. Acad. Sci. U. S. A. 104, 19494-9 (2007).
14. Stringari, C., Cinquin, A., Cinquin, O., Donovan, P. & Gratton, E. In Vivo Identification of Changes in Metabolic State as Stem Cells Differentiate, by Phasor Analysis of Fluorescence Lifetime Imaging. Biophys. J. 100, 183a (2011).
15. Digman, M. A, Caiolfa, V. R., Zamai, M. & Gratton, E. The phasor approach to fluorescence lifetime imaging analysis. Biophys. J. 94, L14-6 (2008).
16. Débarre, D. et al. Imaging lipid bodies in cells and tissues using third-harmonic generation microscopy. Nat. Methods 3, 47-53 (2006).
17. Nan, X., Cheng, J.-X. & Xie, X. S. Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopy. J. Lipid Res. 44, 2202-8 (2003).
18. Krafft, C., Dietzek, B. & Popp, J. Raman and CARS microspectroscopy of cells and tissues. Analyst 134, 1046-57 (2009).
19. Fu, D. et al. In vivo metabolic fingerprinting of neutral lipids with hyperspectral stimulated Raman scattering microscopy. J. Am. Chem. Soc. 136, 8820-8 (2014).
20. Yen, K. et al. A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods. PLoS One 5 (2010).
21. Golfetto, O., Hinde, E. & Gratton, E. Laurdan fluorescence lifetime discriminates cholesterol content from changes in fluidity in living cell membranes. Biophys. J. 104, 1238-47 (2013).
22. Rohwedder, A., Zhang, Q., Rudge, S. A., Michael, J. O. & Wakelam, M. J. O. Lipid droplet formation in response to oleic acid in Huh-7 cells is a fatty acid receptor mediated event. Accepted manuscript. J. Cell Sci. 127, 3104-15 (2014).
23. Fujimoto, Y. et al. Long-chain fatty acids induce lipid droplet formation in a cultured human hepatocyte in a manner dependent of Acyl-CoA synthetase. Biol. Pharm. Bull. 29, 2174-2180 (2006).
24. Gremmels, H. et al. Oleic acid increases mitochondrial reactive oxygen species production and decreases endothelial nitric oxide synthase activity in cultured endothelial cells. Eur. J. Pharmacol. (2015) doi:10.1016/j.ejphar.2015.01.005
25. Wojtczak, L. & Schonfeld, P. Effect of fatty acids on energy coupling processes in mitochondria. Biochim. Biophys. Acta-Bioenerg. 1183, 41-57 (1993).
26. Matthaüs, C. et al. Noninvasive imaging of intracellular lipid metabolism in macrophages by Raman microscopy in combination with stable isotopic labeling. Anal. Chem. 84, 8549-56 (2012).
27. Lambert, J. Introduction to organic spectroscopy. (Macmillan, 1987).
28. Katz, M., Eldred, G. & Jr, W. R. Lipofuscin autofluorescence: evidence for vitamin A involvement in the retina. Mech. Ageing Dev. 39 (1987).
29. Sitte, N., Merker, K., Grune, T. & von Zglinicki, T. Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress. Exp. Gerontol. 36, 475-86 (2001).
30. Schweitzer, D. et al. Time-resolved autofluorescence imaging of human donor retina tissue from donors with significant extramacular drusen. Invest. Ophthalmol. Vis. Sci. 53, 3376-86 (2012).
31. Orban, T., Palczewska, G. & Palczewski, K. Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues. J. Biol. Chem. 286, 17248-58 (2011).
32. Blaner, W. S. et al. Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage. Biochim. Biophys. Acta 1791, 467-73 (2009).
33. Failloux, N., Bonnet, I., Baron, M.-H. & Perrier, E. Quantitative Analysis of Vitamin A Degradation by Raman Spectroscopy. Appl. Spectrosc. 57, 1117-1122 (2003).
34. Crosignani, V., Jahid, S., Dvornikov, A. S. & Gratton, E. A deep tissue fluorescence imaging system with enhanced SHG detection capabilities. Microsc. Res. Tech. 77, 368-73 (2014).