Oxidative stress and glyoxalase i activity mediate dicarbonyl toxicity in MCF-7 mamma carcinoma cells and a tamoxifen resistant derivative

Biochimica et Biophysica Acta - General Subjects

Volumn 1860, Issue 6, 2016, Pages 1272-1280

  Nass, Norbert ^a   Sel, Saadettin ^b   Ignatov, Atanas ^a   Roessner, Albert ^a   Kalinski, Thomas ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Glyoxal; Glyoxalase; MAP kinase signaling; Methylglyoxal; NF B; Protein kinase B (AKT); Reactive oxygen species (ROS)

Indexed keywords

1,2 DICARBONYL DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIPHENYLIODONIUM SALT; LACTOYLGLUTATHIONE LYASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TAMOXIFEN; ALDEHYDE;

ARTICLE; CANCER SURVIVAL; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; MCF 7 CELL LINE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RESAZURIN ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ALDEHYDES; DRUG RESISTANCE, NEOPLASM; HUMANS; LACTOYLGLUTATHIONE LYASE; MAP KINASE SIGNALING SYSTEM; MCF-7 CELLS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TAMOXIFEN;

EID: 84961775804     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2016.03.006     Document Type: Article

References (50)

1. I. Allaman, M. Bélanger, and P.J. Magistretti Methylglyoxal, the dark side of glycolysis Front. Neurosci. 9 2015 23
2. C. Ott, K. Jacobs, E. Haucke, A. Navarrete Santos, T. Grune, and A. Simm Role of advanced glycation end products in cellular signaling Redox Biol. 2 2014 411 429
3. N. Rabbani, and P.J. Thornalley Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome Amino Acids 42 2012 1133 1142
4. M. Upadhyay, J. Samal, M. Kandpal, O.V. Singh, and P. Vivekanandan The Warburg effect: insights from the past decade Pharmacol. Ther. 2012
5. D.J. Creighton, Z.-B. Zheng, R. Holewinski, D.S. Hamilton, and J.L. Eiseman Glyoxalase I inhibitors in cancer chemotherapy Biochem. Soc. Trans. 31 2003 1378 1382
6. J. Lee, J. Song, K. Kwon, S. Jang, C. Kim, K. Baek, J. Kim, and C. Park Human DJ-1 and its homologs are novel glyoxalases Hum. Mol. Genet. 21 2012 3215 3225
7. D. Li, and E.M. Ellis Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells Toxicol. in Vitro 28 2014 707 714
8. P.J. Thornalley, and N. Rabbani Glyoxalase in tumourigenesis and multidrug resistance Semin. Cell Dev. Biol. 22 2011 318 325
9. R.C. Lyon, D. Li, G. McGarvie, and E.M. Ellis Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells Neurochem. Int. 2012
10. A. Rulli, L. Carli, R. Romani, T. Baroni, E. Giovannini, G. Rosi, and V. Talesa Expression of glyoxalase I and II in normal and breast cancer tissues Breast Cancer Res. Treat. 66 2001 67 72
11. X. Geng, J. Ma, F. Zhang, and C. Xu Glyoxalase I in tumor cell proliferation and survival and as a potential target for anticancer therapy Oncol. Res. Treat. 37 2014 570 574
12. F. Hosoda, Y. Arai, N. Okada, H. Shimizu, M. Miyamoto, N. Kitagawa, H. Katai, H. Taniguchi, K. Yanagihara, I. Imoto, J. Inazawa, M. Ohki, and T. Shibata Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer Oncogene 2014 1196 1206
13. P.J. Thornalley Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy Biochem. Soc. Trans. 31 2003 1372 1377
14. M. Ghosh, D. Talukdar, S. Ghosh, N. Bhattacharyya, M. Ray, and S. Ray In vivo assessment of toxicity and pharmacokinetics of methylglyoxal. Augmentation of the curative effect of methylglyoxal on cancer-bearing mice by ascorbic acid and creatine Toxicol. Appl. Pharmacol. 212 2006 45 58
15. S.K. Chia, and A.C. Wolff With maturity comes confidence: EBCTCG tamoxifen update Lancet 378 2011 747 749
16. M. Droog, K. Beelen, S. Linn, and W. Zwart Tamoxifen resistance: from bench to bedside Eur. J. Pharmacol. 2013 47 57
17. G. Li, J. Zhang, K. Jin, K. He, Y. Zheng, X. Xu, H. Wang, H. Wang, Z. Li, X. Yu, X. Teng, J. Cao, and L. Teng Estrogen receptor-α36 is involved in development of acquired tamoxifen resistance via regulating the growth status switch in breast cancer cells Mol. Oncol. 7 2013 611 624
18. S. Thrane, A.E. Lykkesfeldt, M.S. Larsen, B.S. Sorensen, and C.W. Yde Estrogen receptor α is the major driving factor for growth in tamoxifen-resistant breast cancer and supported by HER/ERK signaling Breast Cancer Res. Treat. 139 2013 71 80
19. P. Fan, F.A. Agboke, H.E. Cunliffe, P. Ramos, and V.C. Jordan A molecular model for the mechanism of acquired tamoxifen resistance in breast cancer Eur. J. Cancer (Oxf.) 1990 50 2014 2866 2876
20. N. Nass, and T. Kalinski Tamoxifen resistance: From cell culture experiments towards novel biomarkers Pathol. Res. Pract. 211 2015 189 197
21. A. Ignatov, T. Ignatov, A. Roessner, S.D. Costa, and T. Kalinski Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells Breast Cancer Res. Treat. 123 2010 87 96
22. N. Nass, H.-J. Brömme, R. Hartig, S. Korkmaz, S. Sel, F. Hirche, A. Ward, A. Simm, S. Wiemann, A.E. Lykkesfeldt, A. Roessner, and T. Kalinski Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells PLoS One 9 2014 e101473
23. T. Pourmotabbed, and D.J. Creighton Substrate specificity of bovine liver formaldehyde dehydrogenase J. Biol. Chem. 261 1986 14240 14244
24. M. Arai, N. Nihonmatsu-Kikuchi, M. Itokawa, N. Rabbani, and P.J. Thornalley Measurement of glyoxalase activities Biochem. Soc. Trans. 42 2014 491 494
25. B. Györffy, A. Lanczky, A.C. Eklund, C. Denkert, J. Budczies, Q. Li, and Z. Szallasi An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients Breast Cancer Res. Treat. 123 2010 725 731
26. H.-J. Brömme, L. Zühlke, R.-E. Silber, and A. Simm DCFH2 interactions with hydroxyl radicals and other oxidants - influence of organic solvents Exp. Gerontol. 43 2008 638 644
27. J. Kim, J.-W. Son, J.-A. Lee, Y.-S. Oh, and S.-H. Shinn Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes J. Korean Med. Sci. 19 2004 95 100
28. C.-Y. Tu, Y.-F. Chen, C.-K. Lii, and T.-S. Wang Methylglyoxal induces DNA crosslinks in ECV304 cells via a reactive oxygen species-independent protein carbonylation pathway Toxicol. Vitro Int. J. Publ. Assoc. BIBRA 27 2013 1211 1219
29. F. Hong, J. Bao, J. Hao, Q. Yu, and J. Liu Methylglyoxal and advanced glycation end-products promote cytokines expression in peritoneal mesothelial cells via MAPK signaling Am. J. Med. Sci. 349 2015 105 109
30. W. Li, R.E. Maloney, M.L. Circu, J.S. Alexander, and T.Y. Aw Acute carbonyl stress induces occludin glycation and brain microvascular endothelial barrier dysfunction: role for glutathione-dependent metabolism of methylglyoxal Free Radic. Biol. Med. 54 2013 51 61
31. A. Dhar, I. Dhar, K.M. Desai, and L. Wu Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose Br. J. Pharmacol. 161 2010 1843 1856
32. N. Shangari, W.R. Bruce, R. Poon, and P.J. O'Brien Toxicity of glyoxals - role of oxidative stress, metabolic detoxification and thiamine deficiency Biochem. Soc. Trans. 31 2003 1390 1393
33. M.P. Wautier, O. Chappey, S. Corda, D.M. Stern, A.M. Schmidt, and J.L. Wautier Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE Am. J. Physiol. Endocrinol. Metab. 280 2001 E685 E694
34. K. Higai, A. Shimamura, and K. Matsumoto Amadori-modified glycated albumin predominantly induces E-selectin expression on human umbilical vein endothelial cells through NADPH oxidase activation Clin. Chim. Acta Int. J. Clin. Chem. 367 2006 137 143
35. G. Basta, G. Lazzerini, S. Del Turco, G.M. Ratto, A.M. Schmidt, and R. De Caterina At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products Arterioscler. Thromb. Vasc. Biol. 25 2005 1401 1407
36. A. Gugliucci, and T. Menini The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease Adv. Exp. Med. Biol. 824 2014 191 208
37. B.-F. Liu, S. Miyata, Y. Hirota, S. Higo, H. Miyazaki, M. Fukunaga, Y. Hamada, S. Ueyama, O. Muramoto, A. Uriuhara, and M. Kasuga Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells Kidney Int. 63 2003 947 957
38. S. Kuntz, C. Kunz, and S. Rudloff Carbonyl compounds methylglyoxal and glyoxal affect interleukin-8 secretion in intestinal cells by superoxide anion generation and activation of MAPK p38 Mol. Nutr. Food Res. 54 2010 1458 1467
39. W.-H. Chan, H.-J. Wu, and N.-H. Shiao Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3, and p21-activated kinase 2 J. Cell. Biochem. 100 2007 1056 1069
40. A.A. Akhand, K. Hossain, H. Mitsui, M. Kato, T. Miyata, R. Inagi, J. Du, K. Takeda, Y. Kawamoto, H. Suzuki, K. Kurokawa, and I. Nakashima Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells Free Radic. Biol. Med. 31 2001 20 30
41. M. Fukunaga, S. Miyata, B.F. Liu, H. Miyazaki, Y. Hirota, S. Higo, Y. Hamada, S. Ueyama, and M. Kasuga Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells Biochem. Biophys. Res. Commun. 320 2004 689 695
42. B. Chiavarina, M.-J. Nokin, F. Durieux, E. Bianchi, A. Turtoi, O. Peulen, P. Peixoto, P. Irigaray, K. Uchida, D. Belpomme, P. Delvenne, V. Castronovo, and A. Bellahcène Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes Oncotarget 5 2014 5472 5482
43. M. Xue, N. Rabbani, H. Momiji, P. Imbasi, M.M. Anwar, N. Kitteringham, B.K. Park, T. Souma, T. Moriguchi, M. Yamamoto, and P.J. Thornalley Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation Biochem. J. 443 2012 213 222
44. R. Schiff, P. Reddy, M. Ahotupa, E. Coronado-Heinsohn, M. Grim, S.G. Hilsenbeck, R. Lawrence, S. Deneke, R. Herrera, G.C. Chamness, S.A. Fuqua, P.H. Brown, and C.K. Osborne Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo J. Natl. Cancer Inst. 92 2000 1926 1934
45. Y.-L. Bai, B. Zhou, X.-Y. Jing, B. Zhang, X.-Q. Huo, C. Ma, and J.-M. He Predictive role of GSTs on the prognosis of breast cancer patients with neoadjuvant chemotherapy Asian Pac. J. Cancer Prev. 13 2012 5019 5022
46. S. Kim, D.H. Kim, W.H. Jung, and J.S. Koo The expression of redox proteins in phyllodes tumor Breast Cancer Res. Treat. 141 2013 365 374
47. S. Tulsyan, P. Chaturvedi, G. Agarwal, P. Lal, S. Agrawal, R.D. Mittal, and B. Mittal Pharmacogenetic influence of GST polymorphisms on anthracycline-based chemotherapy responses and toxicity in breast cancer patients: a multi-analytical approach Mol. Diagn. Ther. 17 2013 371 379
48. R.L. Franco, N.G.M. Schenka, A.A. Schenka, L.F. Rezende, and M.S.C. Gurgel Glutathione S-transferase Pi expression in invasive breast cancer and its relation with the clinical outcome J. Buon. Off. J. Balk. Union Oncol. 17 2012 259 264
49. C.M. Woolston, L. Zhang, S.J. Storr, A. Al-Attar, M. Shehata, I.O. Ellis, S.Y. Chan, and S.G. Martin The prognostic and predictive power of redox protein expression for anthracycline-based chemotherapy response in locally advanced breast cancer Mod. Pathol. Off. J. U. S. Can. Acad. Pathol. Inc. 25 2012 1106 1116
50. B.K. Arun, L.A. Granville, G. Yin, L.P. Middleton, S. Dawood, S.-W. Kau, A. Kamal, L. Hsu, G.N. Hortobagyi, and A.A. Sahin Glutathione-s-transferase-pi expression in early breast cancer: association with outcome and response to chemotherapy Cancer Investig. 28 2010 554 559