Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer

Oncogene

Volumn 34, Issue 9, 2015, Pages 1196-1206

  Hosoda, F ^a   Arai, Y ^a   Okada, N ^a   Shimizu, H ^a   Miyamoto, M ^a   Kitagawa, N ^a   Katai, H ^b   Taniguchi, H ^b   Yanagihara, K ^c   Imoto, I ^d,e   Inazawa, J ^d   Ohki, M ^a   Shibata, T ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL   (Japan)

^c NATIONAL CANCER CENTER   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HYDROXYACYLGLUTATHIONE HYDROLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTOYLGLUTATHIONE LYASE; MESSENGER RNA; S 4 BROMOBENZYL GLUTATHIONE CYCLOPENTYL DIESTER; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; ERBB2 PROTEIN, HUMAN; GLUTATHIONE; S-4-BROMOBENZYLGLUTATHIONE CYCLOPENTYL DIESTER;

AMPLICON; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER PROGNOSIS; CARBON METABOLISM; CHROMOSOME 6P; CHROMOSOME 6P21; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; ENERGY YIELD; FEMALE; GASTRIC CANCER CELL LINE; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENOMICS; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; ONCOGENE; PRIMARY TUMOR; PRIORITY JOURNAL; STOMACH CANCER; STOMACH CARCINOGENESIS; 3T3 CELL LINE; ANALOGS AND DERIVATIVES; ANIMAL; CHROMOSOME 6; GENE DOSAGE; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; STOMACH TUMOR; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 6; COMPARATIVE GENOMIC HYBRIDIZATION; GENE AMPLIFICATION; GENE DOSAGE; GENOMICS; GLUTATHIONE; HEK293 CELLS; HUMANS; LACTOYLGLUTATHIONE LYASE; MICE; NF-KAPPA B; NIH 3T3 CELLS; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANSCRIPTION FACTOR AP-1;

EID: 84928271890     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.57     Document Type: Article

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