Methylglyoxal induces DNA crosslinks in ECV304 cells via a reactive oxygen species-independent protein carbonylation pathway

Toxicology in Vitro

Volumn 27, Issue 4, 2013, Pages 1211-1219

  Tu, Chih Yu ^a   Chen, Yun Fang ^b,c   Lii, Chong Kuei ^d   Wang, Tsu Shing ^b,c  

^a TIAN SHENG MEMORIAL HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

DNA protein crosslink; ECV304 cells; Methylglyoxal; Protein carbonylation; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; AMINOGUANIDINE; AMINOTHIOL; ASCORBIC ACID; CELL DNA; CURCUMIN; DICHLORODIHYDROFLUORESCEIN DIACETATE; GLUTATHIONE; METHYLGLYOXAL; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID;

20',70' DICHLOROFLUORESCIN DIACETATE ASSAY; ARTICLE; ASSAY; CELL STRAIN; CELL STRAIN ECV304; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CROSS LINKING; HUMAN; HUMAN CELL; PROTEIN CARBONYLATION; PROTEIN DNA INTERACTION; TIME;

ANTIOXIDANTS; CELL LINE; COMET ASSAY; CROSS-LINKING REAGENTS; DNA; DNA DAMAGE; HUMANS; PROTEIN CARBONYLATION; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES;

BOVINAE;

EID: 84875578500     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.02.011     Document Type: Article

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