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Volumn 146, Issue 1, 2016, Pages 13-31

Reduced insulin secretion function is associated with pancreatic islet redistribution of cell adhesion molecules (CAMs) in diabetic mice after prolonged high-fat diet

Author keywords

Cell adhesion molecules; Cell cell interactions; High fat diet; Insulin secretion; Pancreatic beta cells; Type 2 diabetes mellitus

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CALCIUM; CELL ADHESION MOLECULE; F ACTIN; INSULIN; NERVE CELL ADHESION MOLECULE; PROTEIN ZO1; UVOMORULIN; VASCULAR ENDOTHELIAL CADHERIN; CADHERIN; CATENIN; TJP1 PROTEIN, MOUSE;

EID: 84961665569     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-016-1428-5     Document Type: Article
Times cited : (25)

References (87)
  • 1
    • 0030000980 scopus 로고    scopus 로고
    • Cadherin-catenin complex: protein interactions and their implications for cadherin function
    • COI: 1:CAS:528:DyaK28Xkt1Wqu74%3D, PID: 8806074
    • Aberle H, Schwartz H, Kemler R (1996) Cadherin-catenin complex: protein interactions and their implications for cadherin function. J Cell Biochem 61(4):514–523
    • (1996) J Cell Biochem , vol.61 , Issue.4 , pp. 514-523
    • Aberle, H.1    Schwartz, H.2    Kemler, R.3
  • 2
    • 84868027191 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass
    • COI: 1:CAS:528:DC%2BC38Xhsl2it7vN, PID: 22961079
    • Agudo J, Ayuso E, Jimenez V, Casellas A, Mallol C, Salavert A, Bosch F (2012) Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass. Diabetes 61(11):2851–2861. doi:10.2337/db12-0134
    • (2012) Diabetes , vol.61 , Issue.11 , pp. 2851-2861
    • Agudo, J.1    Ayuso, E.2    Jimenez, V.3    Casellas, A.4    Mallol, C.5    Salavert, A.6    Bosch, F.7
  • 3
    • 0036785664 scopus 로고    scopus 로고
    • Insufficient islet compensation to insulin resistance versus reduced glucose effectiveness in glucose-intolerant mice
    • PID: 12217891
    • Ahrén B, Pacini G (2002) Insufficient islet compensation to insulin resistance versus reduced glucose effectiveness in glucose-intolerant mice. Am J Physiol Endocrinol Metab 283(4):E738–E744
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , Issue.4 , pp. E738-E744
    • Ahrén, B.1    Pacini, G.2
  • 4
    • 0037462972 scopus 로고    scopus 로고
    • Homoassociation of VE-cadherin follows a mechanism common to “classical” cadherins
    • COI: 1:CAS:528:DC%2BD38XpvVWltrg%3D, PID: 12507476
    • Ahrens T, Lambert M, Pertz O, Sasaki T, Schulthess T, Mège RM, Timpl R, Engel J (2003) Homoassociation of VE-cadherin follows a mechanism common to “classical” cadherins. J Mol Biol 325(4):733–742
    • (2003) J Mol Biol , vol.325 , Issue.4 , pp. 733-742
    • Ahrens, T.1    Lambert, M.2    Pertz, O.3    Sasaki, T.4    Schulthess, T.5    Mège, R.M.6    Timpl, R.7    Engel, J.8
  • 6
    • 0024917106 scopus 로고
    • Electrophysiology of the pancreatic β-cell
    • COI: 1:STN:280:DyaK3M3islGguw%3D%3D, PID: 2484976
    • Ashcroft FM, Rorsman P (1989) Electrophysiology of the pancreatic β-cell. Prog Biophys Mol Biol 54:87–143
    • (1989) Prog Biophys Mol Biol , vol.54 , pp. 87-143
    • Ashcroft, F.M.1    Rorsman, P.2
  • 7
    • 0041810192 scopus 로고    scopus 로고
    • Nuclear functions for plasma membrane associated proteins?
    • COI: 1:CAS:528:DC%2BD3sXlvVyjt7Y%3D, PID: 12839493
    • Benmerah A, Scott M, Poupon V, Marullo S (2003) Nuclear functions for plasma membrane associated proteins? Traffic 4:503–511
    • (2003) Traffic , vol.4 , pp. 503-511
    • Benmerah, A.1    Scott, M.2    Poupon, V.3    Marullo, S.4
  • 8
    • 0034046772 scopus 로고    scopus 로고
    • Pathophysiology of impaired pulsatile insulin release
    • COI: 1:CAS:528:DC%2BD3cXltFWhtLs%3D, PID: 10867718
    • Bergsten P (2000) Pathophysiology of impaired pulsatile insulin release. Diabetes Metab Res Rev 16:179–191
    • (2000) Diabetes Metab Res Rev , vol.16 , pp. 179-191
    • Bergsten, P.1
  • 9
    • 34547459515 scopus 로고    scopus 로고
    • Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity
    • COI: 1:CAS:528:DC%2BD2sXptV2ntLw%3D, PID: 17592017
    • Bosco D, Rouiller DG, Halban PA (2007) Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity. J Endocrinol 194(1):21–29
    • (2007) J Endocrinol , vol.194 , Issue.1 , pp. 21-29
    • Bosco, D.1    Rouiller, D.G.2    Halban, P.A.3
  • 10
    • 0030053824 scopus 로고    scopus 로고
    • Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system
    • COI: 1:CAS:528:DyaK28XkvFSqtQ%3D%3D, PID: 8555485
    • Breier G, Breviario F, Caveda L, Berthier R, Schnurch H, Gotsch U, Vestweber D, Risau W, Dejana E (1996) Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood 87:630–641
    • (1996) Blood , vol.87 , pp. 630-641
    • Breier, G.1    Breviario, F.2    Caveda, L.3    Berthier, R.4    Schnurch, H.5    Gotsch, U.6    Vestweber, D.7    Risau, W.8    Dejana, E.9
  • 11
    • 24344459011 scopus 로고    scopus 로고
    • Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
    • COI: 1:CAS:528:DC%2BD2MXhtVersb3K, PID: 15923354
    • Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, Harlan DM, Powers AC (2005) Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem 53(9):1087–1097
    • (2005) J Histochem Cytochem , vol.53 , Issue.9 , pp. 1087-1097
    • Brissova, M.1    Fowler, M.J.2    Nicholson, W.E.3    Chu, A.4    Hirshberg, B.5    Harlan, D.M.6    Powers, A.C.7
  • 12
    • 0037219411 scopus 로고    scopus 로고
    • Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
    • COI: 1:CAS:528:DC%2BD3sXisVaisA%3D%3D, PID: 12502499
    • Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC (2003) Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52(1):102–110
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 13
    • 1542269065 scopus 로고    scopus 로고
    • Differentiating the effects of Cx36 and E-cadherin for proper insulin secretion of MIN6 cells
    • COI: 1:CAS:528:DC%2BD2cXitFKns7c%3D, PID: 15023528
    • Calabrese A, Caton D, Meda P (2004) Differentiating the effects of Cx36 and E-cadherin for proper insulin secretion of MIN6 cells. Exp Cell Res 294:379–391
    • (2004) Exp Cell Res , vol.294 , pp. 379-391
    • Calabrese, A.1    Caton, D.2    Meda, P.3
  • 14
    • 77951953778 scopus 로고    scopus 로고
    • Epithelial–mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease
    • COI: 1:CAS:528:DC%2BC3cXls1Wgur8%3D, PID: 19903090
    • Cannito S, Novo E, Bonzo LV, Busletta C, Colombatto S, Parola M (2010) Epithelial–mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease. Antioxid Redox Signal 12(12):1383–1430. doi:10.1089/ars.2009.2737
    • (2010) Antioxid Redox Signal , vol.12 , Issue.12 , pp. 1383-1430
    • Cannito, S.1    Novo, E.2    Bonzo, L.V.3    Busletta, C.4    Colombatto, S.5    Parola, M.6
  • 15
    • 33646554465 scopus 로고    scopus 로고
    • Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas
    • PID: 16711161
    • Carvalho CPF, Martins JC, Da Cunha DA, Boschero AC, Collares-Buzato CB (2006) Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas. Ann Anat 188:221–234
    • (2006) Ann Anat , vol.188 , pp. 221-234
    • Carvalho, C.P.F.1    Martins, J.C.2    Da Cunha, D.A.3    Boschero, A.C.4    Collares-Buzato, C.B.5
  • 16
    • 77955653525 scopus 로고    scopus 로고
    • Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets
    • COI: 1:CAS:528:DC%2BC3cXmsFyrsbw%3D, PID: 20361177
    • Carvalho CPF, Barbosa HC, Britan A, Santos-Silva JC, Boschero AC, Meda P, Collares-Buzato CB (2010) Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets. Diabetologia 53(7):1428–1437. doi:10.1007/s00125-010-1726-8
    • (2010) Diabetologia , vol.53 , Issue.7 , pp. 1428-1437
    • Carvalho, C.P.F.1    Barbosa, H.C.2    Britan, A.3    Santos-Silva, J.C.4    Boschero, A.C.5    Meda, P.6    Collares-Buzato, C.B.7
  • 18
    • 34548348146 scopus 로고    scopus 로고
    • E-cadherin interactions regulate beta-cell proliferation in islet-like structures
    • COI: 1:CAS:528:DC%2BD2sXps1SgtLw%3D, PID: 17762188
    • Carvell MJ, Marsh PJ, Persaud SJ, Jones PM (2007) E-cadherin interactions regulate beta-cell proliferation in islet-like structures. Cell Physiol Biochem 20(5):617–626
    • (2007) Cell Physiol Biochem , vol.20 , Issue.5 , pp. 617-626
    • Carvell, M.J.1    Marsh, P.J.2    Persaud, S.J.3    Jones, P.M.4
  • 19
    • 54949157651 scopus 로고    scopus 로고
    • Beta-cell failure as a complication of diabetes
    • COI: 1:CAS:528:DC%2BD1cXht1yrurrI, PID: 18777097
    • Chang-Chen KJ, Mullur R, Bernal-Mizrachi E (2008) Beta-cell failure as a complication of diabetes. Rev Endocr Metab Disord 9(4):329–343. doi:10.1007/s11154-008-9101-5
    • (2008) Rev Endocr Metab Disord , vol.9 , Issue.4 , pp. 329-343
    • Chang-Chen, K.J.1    Mullur, R.2    Bernal-Mizrachi, E.3
  • 20
    • 0031809132 scopus 로고    scopus 로고
    • Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia
    • COI: 1:CAS:528:DyaK1cXktVKltb4%3D, PID: 9696347
    • Collares-Buzato CB, Jepson MA, Simmons NL, Hirst BH (1998) Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia. Eur J Cell Biol 76:85–92
    • (1998) Eur J Cell Biol , vol.76 , pp. 85-92
    • Collares-Buzato, C.B.1    Jepson, M.A.2    Simmons, N.L.3    Hirst, B.H.4
  • 21
    • 16644368082 scopus 로고    scopus 로고
    • Upregulation of the expression of tight and adherens junction-associated proteins during maturation of neonatal pancreatic islets in vitro
    • COI: 1:CAS:528:DC%2BD2MXhsVyrsrc%3D, PID: 15609094
    • Collares-Buzato CB, Carvalho CPF, Furtado AG, Boschero AC (2004) Upregulation of the expression of tight and adherens junction-associated proteins during maturation of neonatal pancreatic islets in vitro. J Mol Histol 35:811–822
    • (2004) J Mol Histol , vol.35 , pp. 811-822
    • Collares-Buzato, C.B.1    Carvalho, C.P.F.2    Furtado, A.G.3    Boschero, A.C.4
  • 22
    • 0036120562 scopus 로고    scopus 로고
    • The cadherin-catenin adhesion system in signaling and cancer
    • COI: 1:CAS:528:DC%2BD38XivFKjs7k%3D, PID: 11956233
    • Conacci-Sorrell M, Zhurinsky J, Ben-Ze’ev A (2002) The cadherin-catenin adhesion system in signaling and cancer. J Clin Invest 109:987–991
    • (2002) J Clin Invest , vol.109 , pp. 987-991
    • Conacci-Sorrell, M.1    Zhurinsky, J.2    Ben-Ze’ev, A.3
  • 25
    • 84891806123 scopus 로고    scopus 로고
    • Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis
    • COI: 1:CAS:528:DC%2BC3sXhvV2itLjO, PID: 23630302
    • Dai C, Brissov M, Reinert RB, Nyman L, Liu EH, Thompson C, Powers AC (2013) Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis. Diabetes 62(12):4144–4153. doi:10.2337/db12-1657
    • (2013) Diabetes , vol.62 , Issue.12 , pp. 4144-4153
    • Dai, C.1    Brissov, M.2    Reinert, R.B.3    Nyman, L.4    Liu, E.H.5    Thompson, C.6    Powers, A.C.7
  • 26
    • 0034912203 scopus 로고    scopus 로고
    • Interendothelial junctions and their role in the control of angiogenesis, vascular permeability and leukocyte transmigration
    • COI: 1:CAS:528:DC%2BD3MXlsVektr8%3D, PID: 11487019
    • Dejana E, Spagnuolo R, Bazzoni G (2001) Interendothelial junctions and their role in the control of angiogenesis, vascular permeability and leukocyte transmigration. Thromb Haemost 86:308–315
    • (2001) Thromb Haemost , vol.86 , pp. 308-315
    • Dejana, E.1    Spagnuolo, R.2    Bazzoni, G.3
  • 27
    • 32644445773 scopus 로고    scopus 로고
    • A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6 J mice
    • COI: 1:CAS:528:DC%2BD28XhsFCqurg%3D, PID: 16487855
    • Drolet MC, Roussel E, Deshaies Y, Couet J, Arsenault M (2006) A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6 J mice. J Am Coll Cardiol 47(4):850–855
    • (2006) J Am Coll Cardiol , vol.47 , Issue.4 , pp. 850-855
    • Drolet, M.C.1    Roussel, E.2    Deshaies, Y.3    Couet, J.4    Arsenault, M.5
  • 28
    • 0036214590 scopus 로고    scopus 로고
    • Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin
    • COI: 1:CAS:528:DC%2BD38XisFGitr8%3D, PID: 11897712
    • Duvillie B, Currie C, Chrones T, Bucchini D, Jami J, Joshi RL, Hill DJ (2002) Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin. Endocrinology 143:1530–1537
    • (2002) Endocrinology , vol.143 , pp. 1530-1537
    • Duvillie, B.1    Currie, C.2    Chrones, T.3    Bucchini, D.4    Jami, J.5    Joshi, R.L.6    Hill, D.J.7
  • 29
    • 40949099049 scopus 로고    scopus 로고
    • Organization of multiprotein complexes at cell-cell junction
    • COI: 1:CAS:528:DC%2BD1cXmtlWitLw%3D, PID: 18365233
    • Ebnet K (2008) Organization of multiprotein complexes at cell-cell junction. Histochem Cell Biol 130:1–20. doi:10.1007/s00418-008-0418-7
    • (2008) Histochem Cell Biol , vol.130 , pp. 1-20
    • Ebnet, K.1
  • 30
    • 0345435966 scopus 로고    scopus 로고
    • Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets
    • COI: 1:CAS:528:DyaK1MXmslyqtA%3D%3D, PID: 9922458
    • Esni F, Täljedal IB, Perl AK, Cremer H, Christofori G, Semb H (1999) Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets. J Cell Biol 144(2):325–337
    • (1999) J Cell Biol , vol.144 , Issue.2 , pp. 325-337
    • Esni, F.1    Täljedal, I.B.2    Perl, A.K.3    Cremer, H.4    Christofori, G.5    Semb, H.6
  • 31
    • 74949116364 scopus 로고    scopus 로고
    • Neonatal growth and regeneration of β-cells are regulated by the Wnt/β-catenin signaling in normal and diabetic rats
    • Figeac FBU, Faro M, Chelali N, Portha B, Movassat J (2009) Neonatal growth and regeneration of β-cells are regulated by the Wnt/β-catenin signaling in normal and diabetic rats. Am J Physiol Endocrinol Metab 298:245–256. doi:10.1152/ajpendo.00538.2009
    • (2009) Am J Physiol Endocrinol Metab , vol.298 , pp. 245-256
    • Figeac, F.B.U.1    Faro, M.2    Chelali, N.3    Portha, B.4    Movassat, J.5
  • 32
    • 0027370161 scopus 로고
    • 2+ as evidenced in single pancreatic islets
    • COI: 1:CAS:528:DyaK3sXlslCmsrc%3D, PID: 8226733
    • 2+ as evidenced in single pancreatic islets. J Biol Chem 268:22265–22268
    • (1993) J Biol Chem , vol.268 , pp. 22265-22268
    • Gilon, P.1    Shepherd, R.M.2    Henquin, J.C.3
  • 33
    • 0025047165 scopus 로고
    • Sequential morphological changes in pancreatic islets of spontaneously diabetic rats
    • COI: 1:STN:280:DyaK3M%2FksFynsA%3D%3D, PID: 1978314
    • Gomez-Dumm CL, Semino MC, Gagliardino JJ (1990) Sequential morphological changes in pancreatic islets of spontaneously diabetic rats. Pancreas 5(5):533–539
    • (1990) Pancreas , vol.5 , Issue.5 , pp. 533-539
    • Gomez-Dumm, C.L.1    Semino, M.C.2    Gagliardino, J.J.3
  • 35
    • 84941417995 scopus 로고    scopus 로고
    • Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells
    • COI: 1:CAS:528:DC%2BC2MXls1OqsA%3D%3D, PID: 25559846
    • Green AD, Vasu S, McClenaghan NH, Flatt PR (2015) Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells. Pflugers Arch 467(10):2219–2228. doi:10.1007/s00424-014-1681-1
    • (2015) Pflugers Arch , vol.467 , Issue.10 , pp. 2219-2228
    • Green, A.D.1    Vasu, S.2    McClenaghan, N.H.3    Flatt, P.R.4
  • 36
    • 77953878405 scopus 로고    scopus 로고
    • Adherens junctions: from molecules to morphogenesis
    • COI: 1:CAS:528:DC%2BC3cXnvVShtb4%3D, PID: 20571587
    • Harris TJ, Tepass U (2010) Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol 11(7):502–514. doi:10.1038/nrm2927
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.7 , pp. 502-514
    • Harris, T.J.1    Tepass, U.2
  • 38
    • 0036089387 scopus 로고    scopus 로고
    • Role of nitric oxide synthase isoforms in glucose-stimulated insulin release
    • Henningsson R, Salehi A, Lundquist I (2002) Role of nitric oxide synthase isoforms in glucose-stimulated insulin release. Am J Physiol Cell Physiol 283:296–304
    • (2002) Am J Physiol Cell Physiol , vol.283 , pp. 296-304
    • Henningsson, R.1    Salehi, A.2    Lundquist, I.3
  • 39
    • 70350315739 scopus 로고    scopus 로고
    • Transgenic and other experimental models of pancreas and islet damage
    • Herrera PL (2009) Transgenic and other experimental models of pancreas and islet damage. Diabetes Obes Metab 11(4):81–86. doi:10.1111/j.1463-1326.2009.01104.x
    • (2009) Diabetes Obes Metab , vol.11 , Issue.4 , pp. 81-86
    • Herrera, P.L.1
  • 40
    • 0035197904 scopus 로고    scopus 로고
    • Effects of acetone, methanol, or paraformaldehyde on cellular structure, visualized by reflection contrast microscopy and transmission and scanning electron microscopy
    • COI: 1:CAS:528:DC%2BD3MXpt1Gqtbs%3D, PID: 11759062
    • Hoetelmans RW, Prins FA, Cornelese-ten Velde I, van der Meer J, van de Velde CJ, van Dierendonck JH (2001) Effects of acetone, methanol, or paraformaldehyde on cellular structure, visualized by reflection contrast microscopy and transmission and scanning electron microscopy. Appl Immunohistochem Mol Morphol 9:346–351
    • (2001) Appl Immunohistochem Mol Morphol , vol.9 , pp. 346-351
    • Hoetelmans, R.W.1    Prins, F.A.2    Cornelese-ten Velde, I.3    van der Meer, J.4    van de Velde, C.J.5    van Dierendonck, J.H.6
  • 41
    • 70350314114 scopus 로고    scopus 로고
    • Cell–cell interactions in the endocrine pancreas
    • COI: 1:CAS:528:DC%2BD1MXhsVOlsb3P, PID: 19817798
    • Jain R, Lammert E (2009) Cell–cell interactions in the endocrine pancreas. Diabetes Obes Metab 11(Suppl. 4):159–167. doi:10.1111/j.1463-1326.2009.01102.x
    • (2009) Diabetes Obes Metab , vol.11 , pp. 159-167
    • Jain, R.1    Lammert, E.2
  • 42
    • 77953510208 scopus 로고    scopus 로고
    • N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover
    • COI: 1:CAS:528:DC%2BC3cXptlWltro%3D, PID: 20533404
    • Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H (2010) N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover. Genesis 48(6):374–381. doi:10.1002/dvg.20628
    • (2010) Genesis , vol.48 , Issue.6 , pp. 374-381
    • Johansson, J.K.1    Voss, U.2    Kesavan, G.3    Kostetskii, I.4    Wierup, N.5    Radice, G.L.6    Semb, H.7
  • 43
    • 0033553462 scopus 로고    scopus 로고
    • Chronic hyperglycemia triggers loss of pancreatic cell differentiation in an animal model of diabetes
    • COI: 1:CAS:528:DyaK1MXjsFWqsL8%3D, PID: 10318828
    • Jonas JC, Sharma A, Hasenkamp W, Ilkova H, Patane G, Laybutt R, Weir GC (1999) Chronic hyperglycemia triggers loss of pancreatic cell differentiation in an animal model of diabetes. J Biol Chem 274(20):14112–14121
    • (1999) J Biol Chem , vol.274 , Issue.20 , pp. 14112-14121
    • Jonas, J.C.1    Sharma, A.2    Hasenkamp, W.3    Ilkova, H.4    Patane, G.5    Laybutt, R.6    Weir, G.C.7
  • 44
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 14:840–846
    • (2006) Nature , vol.14 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 46
    • 81055129681 scopus 로고    scopus 로고
    • Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3MXhsFynurzO, PID: 22102895
    • Kilimnik G, Zhao B, Jo J, Periwal V, Witkowski P, Misawa R, Hara M (2011) Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes. PLoS One 6(11):e27445. doi:10.1371/journal.pone.0027445
    • (2011) PLoS One , vol.6 , Issue.11 , pp. 27445
    • Kilimnik, G.1    Zhao, B.2    Jo, J.3    Periwal, V.4    Witkowski, P.5    Misawa, R.6    Hara, M.7
  • 47
    • 70450124317 scopus 로고    scopus 로고
    • Islet architecture: a comparative study
    • PID: 20606719
    • Kim A, Miller K, Jo J, Kilimnik G, Wojcik P, Hara M (2009) Islet architecture: a comparative study. Islets 1(2):129–136. doi:10.4161/isl.1.2.9480
    • (2009) Islets , vol.1 , Issue.2 , pp. 129-136
    • Kim, A.1    Miller, K.2    Jo, J.3    Kilimnik, G.4    Wojcik, P.5    Hara, M.6
  • 48
    • 67649869804 scopus 로고    scopus 로고
    • Shear stress induces internalization of E-cadherin and invasiveness in metastatic oesophageal cancer cells by a Src-dependent pathway
    • COI: 1:CAS:528:DC%2BD1MXntlSjtbw%3D, PID: 19432901
    • Lawler K, O’Sullivan G, Long A, Kenny D (2009) Shear stress induces internalization of E-cadherin and invasiveness in metastatic oesophageal cancer cells by a Src-dependent pathway. Cancer Sci 100:1082–1087
    • (2009) Cancer Sci , vol.100 , pp. 1082-1087
    • Lawler, K.1    O’Sullivan, G.2    Long, A.3    Kenny, D.4
  • 50
    • 0031029677 scopus 로고    scopus 로고
    • Cross-talk between adherens junctions and desmosomes depends on plakoglobin
    • COI: 1:CAS:528:DyaK2sXhsVejtbk%3D, PID: 9049256
    • Lewis JE, Wah JK 3rd, Sass KM, Jensen PJ, Johnson KR, Wheelock MJ (1997) Cross-talk between adherens junctions and desmosomes depends on plakoglobin. J Cell Biol 136(4):919–934
    • (1997) J Cell Biol , vol.136 , Issue.4 , pp. 919-934
    • Lewis, J.E.1    Wah, J.K.2    Sass, K.M.3    Jensen, P.J.4    Johnson, K.R.5    Wheelock, M.J.6
  • 51
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T) method
    • COI: 1:CAS:528:DC%2BD38XhtFelt7s%3D, PID: 11846609
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-Delta Delta C (T) method. Methods 25(4):402–408
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 52
    • 77349116653 scopus 로고    scopus 로고
    • E-cadherin protects primary hepatocyte spheroids from cell death by a caspase-independent mechanism
    • PID: 20003757
    • Luebke-Wheeler JL, Nedredal G, Yee L, Amiot BP, Nyberg SL (2009) E-cadherin protects primary hepatocyte spheroids from cell death by a caspase-independent mechanism. Cell Transplant 18(12):1281–1287. doi:10.3727/096368909X474258
    • (2009) Cell Transplant , vol.18 , Issue.12 , pp. 1281-1287
    • Luebke-Wheeler, J.L.1    Nedredal, G.2    Yee, L.3    Amiot, B.P.4    Nyberg, S.L.5
  • 53
    • 13844251790 scopus 로고    scopus 로고
    • Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures
    • COI: 1:CAS:528:DC%2BD2MXisVKqsrY%3D, PID: 15479950
    • Luther MJ, Davies E, Muller D, Harrison M, Bone AJ, Persaud SJ, Jones PM (2005) Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures. Am J Physiol Endocrinol Metab 288(3):E502–E509
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , Issue.3 , pp. E502-E509
    • Luther, M.J.1    Davies, E.2    Muller, D.3    Harrison, M.4    Bone, A.J.5    Persaud, S.J.6    Jones, P.M.7
  • 54
    • 84921346137 scopus 로고    scopus 로고
    • Protein-mediated interactions of pancreatic islet cells
    • PID: 24278783
    • Meda P (2013) Protein-mediated interactions of pancreatic islet cells. Scientifica 2013:621249. doi:10.1155/2013/621249
    • (2013) Scientifica , vol.2013 , pp. 621249
    • Meda, P.1
  • 55
    • 35348891428 scopus 로고    scopus 로고
    • Gap junctions: basic structure and functions
    • COI: 1:CAS:528:DC%2BD2sXhtFKisbbO, PID: 17934503
    • Mese G, Richard G, White TW (2007) Gap junctions: basic structure and functions. J Invest Dermatol 127(11):2516–2524
    • (2007) J Invest Dermatol , vol.127 , Issue.11 , pp. 2516-2524
    • Mese, G.1    Richard, G.2    White, T.W.3
  • 56
    • 0141529737 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription
    • COI: 1:CAS:528:DC%2BD3sXotVSru7c%3D, PID: 14517306
    • Miravet S, Piedra J, Castaño J, Raurell I, Francí C, Duñach M, García de Herreros A (2003) Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription. Mol Cell Biol 23(20):7391–7402
    • (2003) Mol Cell Biol , vol.23 , Issue.20 , pp. 7391-7402
    • Miravet, S.1    Piedra, J.2    Castaño, J.3    Raurell, I.4    Francí, C.5    Duñach, M.6    García de Herreros, A.7
  • 57
    • 45849093670 scopus 로고    scopus 로고
    • The what, where, when and how of Wnt/beta-catenin signaling in pancreas development
    • PID: 18953422
    • Murtaugh LC (2008) The what, where, when and how of Wnt/beta-catenin signaling in pancreas development. Organogenesis 4(2):81–86
    • (2008) Organogenesis , vol.4 , Issue.2 , pp. 81-86
    • Murtaugh, L.C.1
  • 58
    • 84876231347 scopus 로고    scopus 로고
    • Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death
    • COI: 1:CAS:528:DC%2BC3sXmvVCktLc%3D, PID: 23613946
    • Ngamjariyawat A, Turpaev K, Vasylovska S, Kozlova EN, Welsh N (2013) Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death. PLoS One 8(4):e61828. doi:10.1371/journal.pone.0061828
    • (2013) PLoS One , vol.8 , Issue.4 , pp. 61828
    • Ngamjariyawat, A.1    Turpaev, K.2    Vasylovska, S.3    Kozlova, E.N.4    Welsh, N.5
  • 60
    • 84991201445 scopus 로고    scopus 로고
    • Influence of gender and time diet exposure on endocrine pancreas remodeling in response to high fat diet-induced metabolic disturbances in mice
    • COI: 1:STN:280:DC%2BC2MnovVSktQ%3D%3D, PID: 25819502
    • Oliveira RB, Maschio DA, Carvalho CPF, Collares-Buzato CB (2015) Influence of gender and time diet exposure on endocrine pancreas remodeling in response to high fat diet-induced metabolic disturbances in mice. Ann Anat 200:88–97. doi:10.1016/j.aanat.2015.01.007
    • (2015) Ann Anat , vol.200 , pp. 88-97
    • Oliveira, R.B.1    Maschio, D.A.2    Carvalho, C.P.F.3    Collares-Buzato, C.B.4
  • 61
    • 0017149270 scopus 로고
    • The microanatomy of the islets of Langerhans
    • COI: 1:STN:280:DyaE2s%2Fjtlyruw%3D%3D, PID: 135911
    • Orci L (1976) The microanatomy of the islets of Langerhans. Metabolism 25:1303–1313
    • (1976) Metabolism , vol.25 , pp. 1303-1313
    • Orci, L.1
  • 63
    • 84928211470 scopus 로고    scopus 로고
    • Cadherin engagement improves insulin secretion of single human β-cells
    • COI: 1:CAS:528:DC%2BC2MXjvFanurw%3D, PID: 25277393
    • Parnaud G, Lavallard V, Bedat B, Matthey-Doret D, Morel P, Berney T, Bosco D (2015) Cadherin engagement improves insulin secretion of single human β-cells. Diabetes 64:887–896. doi:10.2337/db14-0257
    • (2015) Diabetes , vol.64 , pp. 887-896
    • Parnaud, G.1    Lavallard, V.2    Bedat, B.3    Matthey-Doret, D.4    Morel, P.5    Berney, T.6    Bosco, D.7
  • 64
    • 0037459077 scopus 로고    scopus 로고
    • Sticky business: orchestrating cellular signals at adherens junctions
    • COI: 1:CAS:528:DC%2BD3sXhs1SnsLc%3D, PID: 12600316
    • Perez-Moreno M, Jamora C, Fuchs E (2003) Sticky business: orchestrating cellular signals at adherens junctions. Cell 112(4):535–548
    • (2003) Cell , vol.112 , Issue.4 , pp. 535-548
    • Perez-Moreno, M.1    Jamora, C.2    Fuchs, E.3
  • 65
    • 77956373690 scopus 로고    scopus 로고
    • B-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass
    • COI: 1:CAS:528:DC%2BC3cXht12kurbE, PID: 20547980
    • Peyot M-L, Pepin E, Lamontagne J, Latour MG, Zarrouki B, Lussier R, Pineda M, Jetton TL, Madiraju MSR, Joly E, Prentki M (2010) B-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes 59:2178–2187
    • (2010) Diabetes , vol.59 , pp. 2178-2187
    • Peyot, M.-L.1    Pepin, E.2    Lamontagne, J.3    Latour, M.G.4    Zarrouki, B.5    Lussier, R.6    Pineda, M.7    Jetton, T.L.8    Madiraju, M.S.R.9    Joly, E.10    Prentki, M.11
  • 66
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • COI: 1:CAS:528:DC%2BD28XmvV2ltLs%3D, PID: 16823478
    • Prentki M, Nolan CJ (2006) Islet beta cell failure in type 2 diabetes. J Clin Invest 116:1802–1812
    • (2006) J Clin Invest , vol.116 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 67
    • 0037435395 scopus 로고    scopus 로고
    • Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data
    • COI: 1:CAS:528:DC%2BD3sXhs1Kks70%3D, PID: 12618301
    • Ramakers C, Ruijter JM, Deprez RH, Moorman AF (2003) Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci Lett 339(1):62–66
    • (2003) Neurosci Lett , vol.339 , Issue.1 , pp. 62-66
    • Ramakers, C.1    Ruijter, J.M.2    Deprez, R.H.3    Moorman, A.F.4
  • 68
    • 0036360977 scopus 로고    scopus 로고
    • (2+) oscillations and pulsatile insulin secretion in islets from ob/ob mice
    • COI: 1:CAS:528:DC%2BD38Xmt1Shs70%3D, PID: 12189446
    • (2+) oscillations and pulsatile insulin secretion in islets from ob/ob mice. Diabetologia 45(8):1154–1163
    • (2002) Diabetologia , vol.45 , Issue.8 , pp. 1154-1163
    • Ravier, M.A.1    Sehlin, J.2    Henquin, J.C.3
  • 69
    • 70349774453 scopus 로고    scopus 로고
    • The transcriptional response of the islet to pregnancy in mice
    • COI: 1:CAS:528:DC%2BD1MXhtlSitbzE, PID: 19574445
    • Rieck S, White P, Schug J, Fox AJ, Smirnova O, Gao N, Kaestner KH (2009) The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol 23(10):1702–1712. doi:10.1210/me.2009-0144
    • (2009) Mol Endocrinol , vol.23 , Issue.10 , pp. 1702-1712
    • Rieck, S.1    White, P.2    Schug, J.3    Fox, A.J.4    Smirnova, O.5    Gao, N.6    Kaestner, K.H.7
  • 70
    • 35848955929 scopus 로고    scopus 로고
    • E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet
    • COI: 1:CAS:528:DC%2BD2sXht1Cku73O, PID: 17982281
    • Rogers GJ, Hodgkin MN, Squires PE (2007) E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet. Cell Physiol Biochem 20(6):987–994
    • (2007) Cell Physiol Biochem , vol.20 , Issue.6 , pp. 987-994
    • Rogers, G.J.1    Hodgkin, M.N.2    Squires, P.E.3
  • 71
    • 0042767611 scopus 로고    scopus 로고
    • Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity
    • COI: 1:CAS:528:DC%2BD3sXlvFCgt7w%3D, PID: 12882911
    • Rossmeisl M, Rim JS, Koza RA, Kozak LP (2003) Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity. Diabetes 52:1958–1966
    • (2003) Diabetes , vol.52 , pp. 1958-1966
    • Rossmeisl, M.1    Rim, J.S.2    Koza, R.A.3    Kozak, L.P.4
  • 72
    • 23644444151 scopus 로고    scopus 로고
    • Insulin resistance and type 2 diabetes in high-fat–fed mice are linked to high glycotoxin intake
    • COI: 1:CAS:528:DC%2BD2MXnt1ynsbY%3D, PID: 16046296
    • Sandu O, Song K, Cai W, Zheng F, Uribarri J, Vlassara H (2005) Insulin resistance and type 2 diabetes in high-fat–fed mice are linked to high glycotoxin intake. Diabetes 54:2314–2319
    • (2005) Diabetes , vol.54 , pp. 2314-2319
    • Sandu, O.1    Song, K.2    Cai, W.3    Zheng, F.4    Uribarri, J.5    Vlassara, H.6
  • 73
    • 84863692697 scopus 로고    scopus 로고
    • Cell-to-cell contact dependence and junctional protein content are correlated with in vivo maturation of pancreatic beta cells
    • COI: 1:CAS:528:DC%2BC38XpvFGhtLs%3D, PID: 22712703
    • Santos-Silva JC, Carvalho CP, de Oliveira RB, Boschero AC, Collares-Buzato CB (2012) Cell-to-cell contact dependence and junctional protein content are correlated with in vivo maturation of pancreatic beta cells. Can J Physiol Pharmacol 90:837–850. doi:10.1139/y2012-064
    • (2012) Can J Physiol Pharmacol , vol.90 , pp. 837-850
    • Santos-Silva, J.C.1    Carvalho, C.P.2    de Oliveira, R.B.3    Boschero, A.C.4    Collares-Buzato, C.B.5
  • 74
    • 0032763007 scopus 로고    scopus 로고
    • Nutritionally induced insulin resistance and receptor defect leading to beta-cell failure in animal models
    • COI: 1:CAS:528:DC%2BD3cXhsFOnuw%3D%3D, PID: 10842665
    • Shafrir E, Ziv E, Mosthaf L (1999) Nutritionally induced insulin resistance and receptor defect leading to beta-cell failure in animal models. Ann N Y Acad Sci 892:223–246
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 223-246
    • Shafrir, E.1    Ziv, E.2    Mosthaf, L.3
  • 75
    • 84922422539 scopus 로고    scopus 로고
    • Concurrent hypermulticolor monitoring of CD31, CD34, CD45 and CD146 endothelial progenitor cell markers for acute myocardial infarction
    • COI: 1:CAS:528:DC%2BC2cXhvVersLvL, PID: 25467496
    • Shim Y, Nam MH, Hyuk SW, Yoon SY, Song JM (2015) Concurrent hypermulticolor monitoring of CD31, CD34, CD45 and CD146 endothelial progenitor cell markers for acute myocardial infarction. Anal Chim Acta 853:501–507. doi:10.1016/j.aca.2014.10.036
    • (2015) Anal Chim Acta , vol.853 , pp. 501-507
    • Shim, Y.1    Nam, M.H.2    Hyuk, S.W.3    Yoon, S.Y.4    Song, J.M.5
  • 76
    • 79960387066 scopus 로고    scopus 로고
    • Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased β cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes
    • COI: 1:CAS:528:DC%2BC3MXovFCktrw%3D, PID: 21613229
    • Shirakawa J, Amo K, Ohminami H, Orime K, Togashi Y, Ito Y, Terauchi Y (2011) Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased β cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes. J Biol Chem 286(29):25467–25476. doi:10.1074/jbc.M110.217216
    • (2011) J Biol Chem , vol.286 , Issue.29 , pp. 25467-25476
    • Shirakawa, J.1    Amo, K.2    Ohminami, H.3    Orime, K.4    Togashi, Y.5    Ito, Y.6    Terauchi, Y.7
  • 77
    • 70349448435 scopus 로고    scopus 로고
    • PKC-delta binds to E-cadherin and mediates EGF-induced cell scattering
    • COI: 1:CAS:528:DC%2BD1MXht1aisLrM, PID: 19591825
    • Singh R, Lei P, Andreadis ST (2009) PKC-delta binds to E-cadherin and mediates EGF-induced cell scattering. Exp Cell Res 315:2899–2913. doi:10.1016/j.yexcr.2009.07.002
    • (2009) Exp Cell Res , vol.315 , pp. 2899-2913
    • Singh, R.1    Lei, P.2    Andreadis, S.T.3
  • 78
    • 12944320856 scopus 로고    scopus 로고
    • Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice
    • COI: 1:CAS:528:DC%2BD2MXltVamtQ%3D%3D, PID: 15624098
    • Sone H, Kagawa Y (2005) Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice. Diabetologia 48:58–67
    • (2005) Diabetologia , vol.48 , pp. 58-67
    • Sone, H.1    Kagawa, Y.2
  • 79
    • 84861962480 scopus 로고    scopus 로고
    • The control of gene expression and cell proliferation by the epithelial apical junctional complex
    • COI: 1:CAS:528:DC%2BC38Xhs1GiurrM, PID: 22928510
    • Spadaro D, Tapia R, Pulimeno P, Citi S (2012) The control of gene expression and cell proliferation by the epithelial apical junctional complex. Essays Biochem 53:83–93. doi:10.1042/bse0530083
    • (2012) Essays Biochem , vol.53 , pp. 83-93
    • Spadaro, D.1    Tapia, R.2    Pulimeno, P.3    Citi, S.4
  • 80
    • 0024229140 scopus 로고
    • Diet-induced type II diabetes in C57BL/6 J mice
    • COI: 1:CAS:528:DyaL1cXls12gsr0%3D, PID: 3044882
    • Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN (1988) Diet-induced type II diabetes in C57BL/6 J mice. Diabetes 37(9):1163–1167
    • (1988) Diabetes , vol.37 , Issue.9 , pp. 1163-1167
    • Surwit, R.S.1    Kuhn, C.M.2    Cochrane, C.3    McCubbin, J.A.4    Feinglos, M.N.5
  • 81
    • 77956392948 scopus 로고    scopus 로고
    • Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus
    • COI: 1:CAS:528:DC%2BC3cXht1Cjsb%2FL, PID: 20425581
    • Tripathy D, Chavez AO (2010) Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus. Curr Diab Rep 10(3):184–191. doi:10.1007/s11892-010-0115-5
    • (2010) Curr Diab Rep , vol.10 , Issue.3 , pp. 184-191
    • Tripathy, D.1    Chavez, A.O.2
  • 82
    • 84876500922 scopus 로고    scopus 로고
    • Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin
    • COI: 1:CAS:528:DC%2BC3sXjslehsr0%3D, PID: 23354125
    • Wakae-Takada N, Xuan S, Watanabe K, Meda P, Leib RL (2013) Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin. Diabetologia 56(4):856–866. doi:10.1007/s00125-012-2824-6
    • (2013) Diabetologia , vol.56 , Issue.4 , pp. 856-866
    • Wakae-Takada, N.1    Xuan, S.2    Watanabe, K.3    Meda, P.4    Leib, R.L.5
  • 83
    • 3543009434 scopus 로고    scopus 로고
    • The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes
    • Winzell MS, Ahrén B (2004) The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 53(suppl 3):215–219
    • (2004) Diabetes , vol.53 , pp. 215-219
    • Winzell, M.S.1    Ahrén, B.2
  • 84
    • 0037414442 scopus 로고    scopus 로고
    • Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding
    • PID: 12711310
    • Winzell MS, Holm C, Ahrén B (2003) Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding. Biochem Biophys Res Commun 304:273–278
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 273-278
    • Winzell, M.S.1    Holm, C.2    Ahrén, B.3
  • 85
    • 0036091921 scopus 로고    scopus 로고
    • Overexpression of dominant-negative mutant hepatocyte nuclear factor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes
    • COI: 1:CAS:528:DC%2BD38Xlt1eitA%3D%3D, PID: 11756330
    • Yamagata K, Nammo T, Moriwaki M, Ihara A, Iizuka K, Yang Q, Satoh T, Li M, Uenaka R, Okita K, Iwahashi H, Zhu Q, Cao Y, Imagawa A, Tochino Y, Hanafusa T, Miyagawa J, Matsuzawa Y (2002) Overexpression of dominant-negative mutant hepatocyte nuclear factor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes. Diabetes 51(1):114–123
    • (2002) Diabetes , vol.51 , Issue.1 , pp. 114-123
    • Yamagata, K.1    Nammo, T.2    Moriwaki, M.3    Ihara, A.4    Iizuka, K.5    Yang, Q.6    Satoh, T.7    Li, M.8    Uenaka, R.9    Okita, K.10    Iwahashi, H.11    Zhu, Q.12    Cao, Y.13    Imagawa, A.14    Tochino, Y.15    Hanafusa, T.16    Miyagawa, J.17    Matsuzawa, Y.18
  • 86
    • 9244238200 scopus 로고    scopus 로고
    • Regulation of desmosome assembly and adhesion
    • COI: 1:CAS:528:DC%2BD2cXhtVSnt7bI, PID: 15561586
    • Yin T, Green KJ (2004) Regulation of desmosome assembly and adhesion. Semin Cell Dev Biol 15(6):665–677
    • (2004) Semin Cell Dev Biol , vol.15 , Issue.6 , pp. 665-677
    • Yin, T.1    Green, K.J.2
  • 87
    • 38949141680 scopus 로고    scopus 로고
    • From endothelial to beta cells: insights into pancreatic islet microendothelium
    • COI: 1:CAS:528:DC%2BD1cXisVamt7s%3D, PID: 18220689
    • Zanone MM, Favaro E, Camussi G (2008) From endothelial to beta cells: insights into pancreatic islet microendothelium. Curr Diabetes Rev 4(1):1–9
    • (2008) Curr Diabetes Rev , vol.4 , Issue.1 , pp. 1-9
    • Zanone, M.M.1    Favaro, E.2    Camussi, G.3


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