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Volumn 6, Issue 11, 2011, Pages

Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CADAVER; CELL EXPANSION; CLINICAL ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET DELTA CELL; QUANTITATIVE ANALYSIS; CASE CONTROL STUDY; COMPARATIVE STUDY; CYTOLOGY; ENZYME IMMUNOASSAY; HISTOLOGY; IMAGE PROCESSING; MIDDLE AGED; ORGAN SIZE; PANCREAS; PATHOLOGY;

EID: 81055129681     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027445     Document Type: Article
Times cited : (100)

References (29)
  • 2
    • 0033854620 scopus 로고    scopus 로고
    • Early detection of undiagnosed diabetes mellitus: a US perspective
    • Harris MI, Eastman RC, (2000) Early detection of undiagnosed diabetes mellitus: a US perspective. Diabetes Metab Res Rev 1: 230-236.
    • (2000) Diabetes Metab Res Rev , vol.1 , pp. 230-236
    • Harris, M.I.1    Eastman, R.C.2
  • 3
    • 53549094111 scopus 로고    scopus 로고
    • Relationship between beta-cell mass and diabetes onset
    • Matveyenko AV, Butler PC, (2008) Relationship between beta-cell mass and diabetes onset. Diabetes Obes Metab 10 (Suppl): 23-31.
    • (2008) Diabetes Obes Metab , vol.10 , Issue.SUPPL , pp. 23-31
    • Matveyenko, A.V.1    Butler, P.C.2
  • 5
    • 38149042694 scopus 로고    scopus 로고
    • An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment
    • Marchetti P, Dotta F, Lauro D, Purrello F, (2008) An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment. Regul Pept 146: 4-11.
    • (2008) Regul Pept , vol.146 , pp. 4-11
    • Marchetti, P.1    Dotta, F.2    Lauro, D.3    Purrello, F.4
  • 6
    • 24344459011 scopus 로고    scopus 로고
    • Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
    • Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, et al. (2005) Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem 53: 1087-1097.
    • (2005) J Histochem Cytochem , vol.53 , pp. 1087-1097
    • Brissova, M.1    Fowler, M.J.2    Nicholson, W.E.3    Chu, A.4    Hirshberg, B.5
  • 7
    • 33144467088 scopus 로고    scopus 로고
    • The unique cytoarchitecture of human pancreatic islets has implications for islet cell function
    • Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, et al. (2006) The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A 103: 2334-2339.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2334-2339
    • Cabrera, O.1    Berman, D.M.2    Kenyon, N.S.3    Ricordi, C.4    Berggren, P.O.5
  • 9
    • 70450124317 scopus 로고    scopus 로고
    • Islet architecture - a comparative study
    • Kim A, Miller K, Jo J, Wojcik P, Kilimnik G, et al. (2009) Islet architecture - a comparative study. Islets 1: 129-136.
    • (2009) Islets , vol.1 , pp. 129-136
    • Kim, A.1    Miller, K.2    Jo, J.3    Wojcik, P.4    Kilimnik, G.5
  • 10
    • 77953388365 scopus 로고    scopus 로고
    • Pancreatic islet plasticity: interspecies comparison of islet architecture and composition
    • Steiner DJ, Kim A, Miller K, Hara M, (2010) Pancreatic islet plasticity: interspecies comparison of islet architecture and composition. Islets 2: 135-145.
    • (2010) Islets , vol.2 , pp. 135-145
    • Steiner, D.J.1    Kim, A.2    Miller, K.3    Hara, M.4
  • 11
    • 0028069771 scopus 로고
    • Regulation of pancreatic beta-cell mass in vivo
    • Bonner-Weir S, (1994) Regulation of pancreatic beta-cell mass in vivo. Recent Prog Horm Res 49: 91-104.
    • (1994) Recent Prog Horm Res , vol.49 , pp. 91-104
    • Bonner-Weir, S.1
  • 12
    • 0033867213 scopus 로고    scopus 로고
    • Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy
    • Montanya E, Nacher V, Biarnés M, Soler J, (2000) Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy. Diabetes 49: 1341-1346.
    • (2000) Diabetes , vol.49 , pp. 1341-1346
    • Montanya, E.1    Nacher, V.2    Biarnés, M.3    Soler, J.4
  • 15
    • 80355139522 scopus 로고    scopus 로고
    • Computer-assisted large-scale visualization and quantification of pancreatic islet mass, size distribution and architecture
    • doi:10.3791/2471
    • Kim A, Kilimnik G, Guo C, Sung J, Jo J, et al. (2011) Computer-assisted large-scale visualization and quantification of pancreatic islet mass, size distribution and architecture. J Vis Exp pii 49: 2471 doi:10.3791/2471.
    • (2011) J Vis Exp pii , vol.49 , pp. 2471
    • Kim, A.1    Kilimnik, G.2    Guo, C.3    Sung, J.4    Jo, J.5
  • 16
    • 0038707331 scopus 로고    scopus 로고
    • Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea
    • Yoon KH, Ko SH, Cho JH, Lee JM, Ahn YB, et al. (2003) Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 88: 2300-2308.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2300-2308
    • Yoon, K.H.1    Ko, S.H.2    Cho, J.H.3    Lee, J.M.4    Ahn, Y.B.5
  • 17
    • 77951853210 scopus 로고    scopus 로고
    • Unique arrangement of alpha- and beta-cells in human islets of Langerhans
    • Bosco D, Armanet M, Morel P, Niclauss N, Sgrol A, et al. (2010) Unique arrangement of alpha- and beta-cells in human islets of Langerhans. Diabetes 59: 1202-10.
    • (2010) Diabetes , vol.59 , pp. 1202-1210
    • Bosco, D.1    Armanet, M.2    Morel, P.3    Niclauss, N.4    Sgrol, A.5
  • 18
    • 79959756257 scopus 로고    scopus 로고
    • Pancreatic alpha cell mass in European subjects with type 2 diabetes
    • Henquin JC, Rahier J, (2011) Pancreatic alpha cell mass in European subjects with type 2 diabetes. Diabetologia 54: 1720-1725.
    • (2011) Diabetologia , vol.54 , pp. 1720-1725
    • Henquin, J.C.1    Rahier, J.2
  • 19
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • Prentki M, Nolan CJ, (2006) Islet beta cell failure in type 2 diabetes. J Clin Invest 116: 1802-1812.
    • (2006) J Clin Invest , vol.116 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 20
    • 53549094111 scopus 로고    scopus 로고
    • Relationship between beta-cell mass and diabetes onset
    • Matveyenko AV, Butler PC, (2008) Relationship between beta-cell mass and diabetes onset. Diabetes Obes Metab 10 (Suppl 4): 23-31.
    • (2008) Diabetes Obes Metab , vol.10 , Issue.SUPPL. 4 , pp. 23-31
    • Matveyenko, A.V.1    Butler, P.C.2
  • 21
    • 0020623615 scopus 로고
    • Cellular composition of the human diabetic pancreas
    • Rahier J, Goebbels RM, Henquin JC, (1983) Cellular composition of the human diabetic pancreas. Diabetologia 24: 366-371.
    • (1983) Diabetologia , vol.24 , pp. 366-371
    • Rahier, J.1    Goebbels, R.M.2    Henquin, J.C.3
  • 22
    • 0024213009 scopus 로고
    • Islet amyloid, increased alpha-cells, reduced beta-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes
    • Clark A, Wells CA, Buley ID, Cruickshank JK, Vanhegan RI, et al. (1988) Islet amyloid, increased alpha-cells, reduced beta-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes. Diabetes Research 9: 151-159.
    • (1988) Diabetes Research , vol.9 , pp. 151-159
    • Clark, A.1    Wells, C.A.2    Buley, I.D.3    Cruickshank, J.K.4    Vanhegan, R.I.5
  • 23
    • 0037219411 scopus 로고    scopus 로고
    • Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
    • Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, et al. (2003) Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52: 102-110.
    • (2003) Diabetes , vol.52 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5
  • 24
    • 0038707331 scopus 로고    scopus 로고
    • Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea
    • Yoon KH, Ko SH, Cho JH, Lee JM, Ahn YB, et al. (2003) Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 88: 2300-2308.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2300-2308
    • Yoon, K.H.1    Ko, S.H.2    Cho, J.H.3    Lee, J.M.4    Ahn, Y.B.5
  • 25
    • 12244284000 scopus 로고    scopus 로고
    • Beta- and alpha-cell dysfunction in type 2 diabetes
    • Del Prato S, Marchetti P, (2004) Beta- and alpha-cell dysfunction in type 2 diabetes. Horm Metab Res 36: 775-781.
    • (2004) Horm Metab Res , vol.36 , pp. 775-781
    • Del Prato, S.1    Marchetti, P.2
  • 26
    • 10744222060 scopus 로고    scopus 로고
    • Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects
    • Deng S, Vatamaniuk M, Huang X, Doliba N, Lian MM, et al. (2004) Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects. Diabetes 53: 624-632.
    • (2004) Diabetes , vol.53 , pp. 624-632
    • Deng, S.1    Vatamaniuk, M.2    Huang, X.3    Doliba, N.4    Lian, M.M.5
  • 27
    • 0027161335 scopus 로고
    • Why pancreatic islets burst but single beta cells do not. The heterogeneity hypothesis
    • Smolen P, Rinzel J, Sherman A, (1993) Why pancreatic islets burst but single beta cells do not. The heterogeneity hypothesis. Biophys J 64: 1668-80.
    • (1993) Biophys J , vol.64 , pp. 1668-1680
    • Smolen, P.1    Rinzel, J.2    Sherman, A.3
  • 28
    • 24144463906 scopus 로고    scopus 로고
    • How noise and coupling induce bursting action potentials in pancreatic beta-cells
    • Jo J, Kang H, Choi MY, Koh DS, (2005) How noise and coupling induce bursting action potentials in pancreatic beta-cells. Biophys J 89: 1534-1542.
    • (2005) Biophys J , vol.89 , pp. 1534-1542
    • Jo, J.1    Kang, H.2    Choi, M.Y.3    Koh, D.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.