Cadherin engagement protects human β-cells from apoptosis

Endocrinology

Volumn 152, Issue 12, 2011, Pages 4601-4609

  Parnaud, Géraldine ^a   Gonelle Gispert, Carmen ^a   Morel, Philippe ^a   Giovannoni, Laurianne ^a   Muller, Yannick D ^a   Meier, Raphael ^a   Borot, Sophie ^a   Berney, Thierry ^a   Bosco, Domenico ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; GLASS; IMMUNOGLOBULIN FC FRAGMENT; NERVE CELL ADHESION MOLECULE; P CADHERIN; UVOMORULIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL AGGREGATION; CELL CULTURE; CELL ISOLATION; CELL PROTECTION; CELL SURFACE; CELL VIABILITY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; SYSTEMATIC REVIEW; WESTERN BLOTTING;

ANTIGENS, SURFACE; APOPTOSIS; CADHERINS; CELL ADHESION; CELL SURVIVAL; HUMANS; INSULIN-SECRETING CELLS; PROTECTIVE AGENTS;

EID: 82355190875     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1286     Document Type: Article

References (40)

1. Johnson JD, Luciani DS 2010 Mechanisms of pancreatic β-cell apoptosis in diabetes and its therapies. Adv Exp Med Biol 654:447-462
2. Thomas HE, McKenzie MD, Angstetra E, Campbell PD, Kay TW 2009 β Cell apoptosis in diabetes. Apoptosis 14:1389-1404
3. Emamaullee JA, Shapiro AM 2006 Interventional strategies to prevent β-cell apoptosis in islet transplantation. Diabetes 55:1907-1914 (Pubitemid 44509961)
4. Reffet S, Thivolet C 2006 Immunology of pancreatic islet transplantation. Diabetes Metab 32:523-526 (Pubitemid 44836983)
5. Chiarugi P, Giannoni E 2008 Anoikis: a necessary death program for anchorage-dependent cells. Biochem Pharmacol 76:1352-1364
6. Grossmann J 2002 Molecular mechanisms of "detachment-induced apoptosis-Anoikis." Apoptosis 7:247-260
7. Hammar E, Parnaud G, Bosco D, Perriraz N, Maedler K, Donath M, Rouiller DG, Halban PA 2004 Extracellular matrix protects pancreatic β-cells against apoptosis: role of short- and long-term signaling pathways. Diabetes 53:2034-2041 (Pubitemid 38970752)
8. Pinkse GG, Bouwman WP, Jiawan-Lalai R, Terpstra OT, Bruijn JA, de Heer E 2006 Integrin signaling via RGD peptides and anti-β1 antibodies confers resistance to apoptosis in islets of Langerhans. Diabetes 55:312-317 (Pubitemid 43343258)
9. Ris F, Hammar E, Bosco D, Pilloud C, Maedler K, Donath MY, Oberholzer J, Zeender E, Morel P, Rouiller D, Halban PA 2002 Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human β-cells in vitro. Diabetologia 45:841-850
10. Nlend RN, Michon L, Bavamian S, Boucard N, Caille D, Cancela J, Charollais A, Charpantier E, Klee P, Peyrou M, Populaire C, Zulianello L, Meda P 2006 Connexin36 and pancreatic β-cell functions. Arch Physiol Biochem 112:74-81
11. Kyriakakis E, Philippova M, Joshi MB, Pfaff D, Bochkov V, Afonyushkin T, Erne P, Resink TJ 2010 T-cadherin attenuates the PERK branch of the unfolded protein response and protects vascular endothelial cells from endoplasmic reticulum stress-induced apoptosis. Cell Signal 22:1308-1316
12. Haÿ E, Nouraud A, Marie PJ 2009 N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling. PLoS One 4:e8284
13. Koutsouki E, Beeching CA, Slater SC, Blaschuk OW, Sala-Newby GB, George SJ 2005 N-cadherin-dependent cell-cell contacts promote human saphenous vein smooth muscle cell survival. Arterioscler Thromb Vasc Biol 25:982-988 (Pubitemid 40627843)
14. Li K, He W, Lin N, Wang X, Fan QX 2010 Downregulation of N-cadherin expression inhibits invasiveness, arrests cell cycle and induces cell apoptosis in esophageal squamous cell carcinoma. Cancer Invest 28:479-486
15. Luebke-Wheeler JL, Nedredal G, Yee L, Amiot BP, Nyberg SL 2009 E-cadherin protects primary hepatocyte spheroids from cell death by a caspase-independent mechanism. Cell Transplant 18:1281-1287
16. Pontoriero GF, Smith AN, Miller LA, Radice GL, West-Mays JA, Lang RA 2009 Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Dev Biol 326:403-417
17. Dahl U, Sjødin A, Semb H 1996 Cadherins regulate aggregation of pancreatic β-cells in vivo. Development 122:2895-2902 (Pubitemid 26326520)
18. Yamagata K, Nammo T, Moriwaki M, Ihara A, Iizuka K, Yang Q, Satoh T, Li M, Uenaka R, Okita K, Iwahashi H, Zhu Q, Cao Y, Imagawa A, Tochino Y, Hanafusa T, Miyagawa J, Matsuzawa Y 2002 Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 α in pancreatic β-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced β-cell proliferation, and diabetes. Diabetes 51:114-123 (Pubitemid 34517987)
19. Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, StoffelM 2002 Profound defects in pancreatic β-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1α, and Hnf-3β. Proc Natl Acad Sci USA 99:3818-3823 (Pubitemid 34252189)
20. Bosco D, Rouiller DG, Halban PA 2007 Differential expression of E-cadherin at the surface of rat β-cells as a marker of functional heterogeneity. J Endocrinol 194:21-29 (Pubitemid 47162883)
21. Jaques F, Jousset H, Tomas A, Prost AL, Wollheim CB, Irminger JC, Demaurex N, Halban PA 2008 Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion. Endocrinology 149:2494-2505 (Pubitemid 351574512)
22. Kovacs EM, Ali RG, McCormack AJ, Yap AS 2002 E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts. J Biol Chem 277:6708-6718 (Pubitemid 34968474)
23. Bucher P, Mathe Z, Morel P, Bosco D, Andres A, Kurfuest M, Friedrich O, Raemsch-Guenther N, Buhler LH, Berney T 2005 Assessment of a novel two-component enzyme preparation for human islet isolation and transplantation. Transplantation 79:91-97 (Pubitemid 40140006)
24. Ricordi C, Lacy PE, Scharp DW 1989 Automated islet isolation from human pancreas. Diabetes 38(Suppl 1):140-142 (Pubitemid 19029262)
25. Parnaud G, Bosco D, Berney T, Pattou F, Kerr-Conte J, Donath MY, Bruun C, Mandrup-Poulsen T, Billestrup N, Halban PA 2008 Proliferation of sorted human and rat β cells. Diabetologia 51:91-100 (Pubitemid 50002201)
26. Nose A, Takeichi M 1986 A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos. J Cell Biol 103:2649-2658 (Pubitemid 17008011)
27. Benson DL, Tanaka H 1998 N-cadherin redistribution during synaptogenesis in hippocampal neurons. J Neurosci 18:6892-6904 (Pubitemid 28388019)
28. Cirulli V, Baetens D, Rutishauser U, Halban PA, Orci L, Rouiller DG 1994 Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation. J Cell Sci 107(Pt 6):1429-1436 (Pubitemid 24198462)
29. Bernard-Kargar C, Kassis N, Berthault MF, Pralong W, Ktorza A 2001 Sialylated form of the neural cell adhesion molecule (NCAM): a new tool for the identification and sorting of β-cell subpopulations with different functional activity. Diabetes 50(Suppl 1):S125-S130 (Pubitemid 32148234)
30. Esni F, Täljedal IB, Perl AK, Cremer H, Christofori G, Semb H 1999 Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets. J Cell Biol 144:325-337 (Pubitemid 29066035)
31. Bavamian S, Klee P, Britan A, Populaire C, Caille D, Cancela J, Charollais A, Meda P 2007 Islet-cell-to-cell communication as basis for normal insulin secretion. Diabetes Obes Metab 9(Suppl 2):118-132 (Pubitemid 47543134)
32. Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P 2009 Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression. Hum Mol Genet 18:428-439
33. Sutton VR, Trapani JA 2010 Proteases in lymphocyte killer function: redundancy, polymorphism and questions remaining. Biol Chem 391:873-879
34. Feng Y, Wang D, Yuan R, Parker CM, Farber DL, Hadley GA 2002 CD103 expression is required for destruction of pancreatic islet allografts by CD8(+) T cells. J Exp Med 196:877-886
35. Hirohashi S 1998 Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 153:333-339 (Pubitemid 28373643)
36. Mohamet L, Lea ML, Ward CM 2010 Abrogation of E-cadherin-mediated cellular aggregation allows proliferation of pluripotent mouse embryonic stem cells in shake flask bioreactors. PLoS One 5:e12921
37. Carvell MJ, Marsh PJ, Persaud SJ, Jones PM 2007 E-cadherin interactions regulate β-cell proliferation in islet-like structures. Cell Physiol Biochem 20:617-626 (Pubitemid 47340622)
38. Liu WF, Nelson CM, Pirone DM, Chen CS 2006 E-cadherin engagement stimulates proliferation via Rac1. J Cell Biol 173:431-441
39. Arulanandam R, Vultur A, Cao J, Carefoot E, Elliott BE, Truesdell PF, Larue L, Feracci H, Raptis L 2009 Cadherin-cadherin engagement promotes cell survival via Rac1/Cdc42 and signal transducer and activator of transcription-3. Mol Cancer Res 7:1310-1327
40. Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, Ciliberto G, Moscinski L, Fernández-Luna JL, Nuñez G, Dalton WS, Jove R 1999 Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10:105-115 (Pubitemid 29077388)