메뉴 건너뛰기




Volumn 36, Issue 12, 2016, Pages 3541-3551

Agonist-specific recruitment of arrestin isoforms differentially modify delta opioid receptor function

Author keywords

Arrestin; DRG; GPCR; Pain; Resensitization; Tolerance

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; ARM 390; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; JNJ 20788560; RETINA S ANTIGEN; UNCLASSIFIED DRUG; 4-(ALPHA-(4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL)-N,N-DIETHYLBENZAMIDE; BENZAMIDE DERIVATIVE; ISOPROTEIN; PIPERAZINE DERIVATIVE;

EID: 84961627430     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4124-15.2016     Document Type: Article
Times cited : (55)

References (54)
  • 1
    • 47249147029 scopus 로고    scopus 로고
    • Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins
    • Audet N, Galés C, Archer-Lahlou E, Vallières M, Schiller PW, Bouvier M, Pineyro G (2008) Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins. J Biol Chem 283:15078–15088.
    • (2008) J Biol Chem , vol.283 , pp. 15078-15088
    • Audet, N.1    Galés, C.2    Archer-Lahlou, E.3    Vallières, M.4    Schiller, P.W.5    Bouvier, M.6    Pineyro, G.7
  • 2
    • 84859361248 scopus 로고    scopus 로고
    • Differential association of receptorGbetagamma complexes with beta-arrestin2 determines recycling bias and potential for tolerance of delta opioid receptor agonists
    • Audet N, Charfi I, Mnie-Filali O, Amraei M, Chabot-Doré AJ, Millecamps M, Stone LS, Pineyro G (2012) Differential association of receptorGbetagamma complexes with beta-arrestin2 determines recycling bias and potential for tolerance of delta opioid receptor agonists. J Neurosci 32:4827–4840.
    • (2012) J Neurosci , vol.32 , pp. 4827-4840
    • Audet, N.1    Charfi, I.2    Mnie-Filali, O.3    Amraei, M.4    Chabot-Doré, A.J.5    Millecamps, M.6    Stone, L.S.7    Pineyro, G.8
  • 3
    • 0034619796 scopus 로고    scopus 로고
    • Muopioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence
    • Bohn LM, Gainetdinov RR, Lin FT, Lefkowitz RJ, Caron MG (2000) Muopioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature 408:720–723.
    • (2000) Nature , vol.408 , pp. 720-723
    • Bohn, L.M.1    Gainetdinov, R.R.2    Lin, F.T.3    Lefkowitz, R.J.4    Caron, M.G.5
  • 4
    • 0036895747 scopus 로고    scopus 로고
    • Differential mechanisms of morphine antinociceptive tolerance revealed in (Beta)arrestin-2 knockout mice
    • Bohn LM, Lefkowitz RJ, Caron MG (2002) Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knockout mice. J Neurosci 22:10494–10500.
    • (2002) J Neurosci , vol.22 , pp. 10494-10500
    • Bohn, L.M.1    Lefkowitz, R.J.2    Caron, M.G.3
  • 5
    • 65549153181 scopus 로고    scopus 로고
    • G protein independent phosphorylation and internalization of the delta-opioid receptor
    • Bradbury FA, Zelnik JC, Traynor JR (2009) G protein independent phosphorylation and internalization of the delta-opioid receptor. J Neurochem 109:1526–1535.
    • (2009) J Neurochem , vol.109 , pp. 1526-1535
    • Bradbury, F.A.1    Zelnik, J.C.2    Traynor, J.R.3
  • 9
    • 84920120698 scopus 로고    scopus 로고
    • Identifying ligand-specific signaling within biased responses: Focus on delta opioid receptor (Dop) ligands
    • Charfi I, Audet N, Bagheri Tudashki H, Pineyro G (2015) Identifying ligand-specific signaling within biased responses: focus on delta opioid receptor (Dop) ligands. Br J Pharmacol 172:435–448.
    • (2015) Br J Pharmacol , vol.172 , pp. 435-448
    • Charfi, I.1    Audet, N.2    Bagheri Tudashki, H.3    Pineyro, G.4
  • 10
    • 84961653022 scopus 로고    scopus 로고
    • Beta-arrestin 2 dependence of delta opioid receptor agonists is correlated with alcohol intake
    • Chiang T, Sansuk K, van Rijn RM (2015) Beta-arrestin 2 dependence of delta opioid receptor agonists is correlated with alcohol intake. Br J Pharmacol. In press
    • (2015) Br J Pharmacol
    • Chiang, T.1    Sansuk, K.2    Van Rijn, R.M.3
  • 11
    • 63849100896 scopus 로고    scopus 로고
    • JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence
    • Codd EE, Carson JR, Colburn RW, Stone DJ, Van Besien CR, Zhang SP, Wade PR, Gallantine EL, Meert TF, Molino L, Pullan S, Razler CM, Dax SL, Flores CM (2009) JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. J Pharmacol Exp Ther 329:241–251.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 241-251
    • Codd, E.E.1    Carson, J.R.2    Colburn, R.W.3    Stone, D.J.4    Van Besien, C.R.5    Zhang, S.P.6    Wade, P.R.7    Gallantine, E.L.8    Meert, T.F.9    Molino, L.10    Pullan, S.11    Razler, C.M.12    Dax, S.L.13    Flores, C.M.14
  • 12
    • 84920196160 scopus 로고    scopus 로고
    • Christie MJ (2015) beta-Arrestin-2 knock-out prevents development of cellular mu-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons
    • Connor M, Bagley EE, Chieng BC, Christie MJ (2015) beta-Arrestin-2 knock-out prevents development of cellular mu-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons. Br J Pharmacol 172:492–500.
    • Br J Pharmacol , vol.172 , pp. 492-500
    • Connor, M.1    Bagley, E.E.2    Chieng, B.C.3
  • 13
    • 38549167408 scopus 로고    scopus 로고
    • Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer
    • Coulon V, Audet M, Homburger V, Bockaert J, Fagni L, Bouvier M, Perroy J (2008) Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophys J 94:1001–1009.
    • (2008) Biophys J , vol.94 , pp. 1001-1009
    • Coulon, V.1    Audet, M.2    Homburger, V.3    Bockaert, J.4    Fagni, L.5    Bouvier, M.6    Perroy, J.7
  • 14
    • 84857476249 scopus 로고    scopus 로고
    • Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons
    • Dang VC, Christie MJ (2012) Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons. Br J Pharmacol 165:1704–1716.
    • (2012) Br J Pharmacol , vol.165 , pp. 1704-1716
    • Dang, V.C.1    Christie, M.J.2
  • 15
    • 84867802836 scopus 로고    scopus 로고
    • Deciphering micro-opioid receptor phosphorylation and dephosphorylation in HEK293 cells
    • Doll C, Pöll F, Peuker K, Loktev A, Glück L, Schulz S (2012) Deciphering micro-opioid receptor phosphorylation and dephosphorylation in HEK293 cells. Br J Pharmacol 167:1259–1270.
    • (2012) Br J Pharmacol , vol.167 , pp. 1259-1270
    • Doll, C.1    Pöll, F.2    Peuker, K.3    Loktev, A.4    Glück, L.5    Schulz, S.6
  • 16
    • 34447642715 scopus 로고    scopus 로고
    • The evasive nature of drug efficacy: Implications for drug discovery
    • Galandrin S, Oligny-Longpré G, Bouvier M (2007) The evasive nature of drug efficacy: implications for drug discovery. Trends Pharmacol Sci 28: 423–430.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 423-430
    • Galandrin, S.1    Oligny-Longpré, G.2    Bouvier, M.3
  • 18
    • 84920159838 scopus 로고    scopus 로고
    • Recent advances on the δ opioid receptor: From trafficking to function
    • Gendron L, Mittal N, Beaudry H, Walwyn W (2015) Recent advances on the δ opioid receptor: from trafficking to function. Br J Pharmacol 172:403– 419.
    • (2015) Br J Pharmacol , vol.172 , pp. 403-419
    • Gendron, L.1    Mittal, N.2    Beaudry, H.3    Walwyn, W.4
  • 19
    • 80052416572 scopus 로고    scopus 로고
    • Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation
    • Groer CE, Schmid CL, Jaeger AM, Bohn LM (2011) Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation. J Biol Chem 286:31731–31741.
    • (2011) J Biol Chem , vol.286 , pp. 31731-31741
    • Groer, C.E.1    Schmid, C.L.2    Jaeger, A.M.3    Bohn, L.M.4
  • 20
    • 57649213524 scopus 로고    scopus 로고
    • Agonistselective, receptor-specific interaction of human P2Y receptors with betaarrestin-1 and -2
    • Hoffmann C, Ziegler N, Reiner S, Krasel C, Lohse MJ (2008) Agonistselective, receptor-specific interaction of human P2Y receptors with betaarrestin-1 and -2. J Biol Chem 283:30933–30941.
    • (2008) J Biol Chem , vol.283 , pp. 30933-30941
    • Hoffmann, C.1    Ziegler, N.2    Reiner, S.3    Krasel, C.4    Lohse, M.J.5
  • 23
    • 0043235844 scopus 로고    scopus 로고
    • Ligand-selective receptor conformations revisited: The promise and the problem
    • Kenakin T (2003) Ligand-selective receptor conformations revisited: the promise and the problem. Trends Pharmacol Sci 24:346–354.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 346-354
    • Kenakin, T.1
  • 24
    • 84857497773 scopus 로고    scopus 로고
    • Biased signalling and allosteric machines: New vistas and challenges for drug discovery
    • Kenakin TP (2012) Biased signalling and allosteric machines: new vistas and challenges for drug discovery. Br J Pharmacol 165:1659–1669.
    • (2012) Br J Pharmacol , vol.165 , pp. 1659-1669
    • Kenakin, T.P.1
  • 25
    • 0034711224 scopus 로고    scopus 로고
    • Hierarchical phosphorylation of delta-opioid receptor regulates agonistinduced receptor desensitization and internalization
    • Kouhen OM, Wang G, Solberg J, Erickson LJ, Law PY, Loh HH (2000) Hierarchical phosphorylation of delta-opioid receptor regulates agonistinduced receptor desensitization and internalization. J Biol Chem 275: 36659–36664.
    • (2000) J Biol Chem , vol.275 , pp. 36659-36664
    • Kouhen, O.M.1    Wang, G.2    Solberg, J.3    Erickson, L.J.4    Law, P.Y.5    Loh, H.H.6
  • 26
    • 42149181885 scopus 로고    scopus 로고
    • Structural diversity of G proteincoupled receptors and significance for drug discovery
    • Lagerström MC, Schiöth HB (2008) Structural diversity of G proteincoupled receptors and significance for drug discovery. Nat Rev Drug Discov 7:339–357.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 339-357
    • Lagerström, M.C.1    Schiöth, H.B.2
  • 28
    • 0034644652 scopus 로고    scopus 로고
    • Deltorphin II-induced rapid desensitization of delta-opioid receptor requires both phosphorylation and internalization of the receptor
    • Law PY, Kouhen OM, Solberg J, Wang W, Erickson LJ, Loh HH (2000) Deltorphin II-induced rapid desensitization of delta-opioid receptor requires both phosphorylation and internalization of the receptor. J Biol Chem 275:32057–32065.
    • (2000) J Biol Chem , vol.275 , pp. 32057-32065
    • Law, P.Y.1    Kouhen, O.M.2    Solberg, J.3    Wang, W.4    Erickson, L.J.5    Loh, H.H.6
  • 29
    • 0037013307 scopus 로고    scopus 로고
    • Mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin
    • Lowe JD, Celver JP, Gurevich VV, Chavkin C (2002) mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin. J Biol Chem 277:15729–15735.
    • (2002) J Biol Chem , vol.277 , pp. 15729-15735
    • Lowe, J.D.1    Celver, J.P.2    Gurevich, V.V.3    Chavkin, C.4
  • 30
    • 84896703861 scopus 로고    scopus 로고
    • Minireview: More than just a hammer: Ligand “bias” and pharmaceutical discovery
    • Luttrell LM (2014) Minireview: More than just a hammer: ligand “bias” and pharmaceutical discovery. Mol Endocrinol 28:281–294.
    • (2014) Mol Endocrinol , vol.28 , pp. 281-294
    • Luttrell, L.M.1
  • 32
    • 84920179109 scopus 로고    scopus 로고
    • Prolonged morphine treatment alters delta opioid receptor post-internalization trafficking
    • Ong EW, Xue L, Olmstead MC, Cahill CM (2015) Prolonged morphine treatment alters delta opioid receptor post-internalization trafficking. Br J Pharmacol 172:615–629.
    • (2015) Br J Pharmacol , vol.172 , pp. 615-629
    • Ong, E.W.1    Xue, L.2    Olmstead, M.C.3    Cahill, C.M.4
  • 33
    • 77449116579 scopus 로고    scopus 로고
    • Subcellular dynamic imaging of protein-protein interactions in live cells by bioluminescence resonance energy transfer
    • Perroy J (2010) Subcellular dynamic imaging of protein-protein interactions in live cells by bioluminescence resonance energy transfer. Methods Mol Biol 591:325–333.
    • (2010) Methods Mol Biol , vol.591 , pp. 325-333
    • Perroy, J.1
  • 38
  • 39
    • 34547930932 scopus 로고    scopus 로고
    • Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization
    • Qiu Y, Loh HH, Law PY (2007) Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization. J Biol Chem 282:22315–22323.
    • (2007) J Biol Chem , vol.282 , pp. 22315-22323
    • Qiu, Y.1    Loh, H.H.2    Law, P.Y.3
  • 40
    • 78149500969 scopus 로고    scopus 로고
    • The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics
    • Raehal KM, Bohn LM (2011) The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics. Neuropharmacology 60:58–65.
    • (2011) Neuropharmacology , vol.60 , pp. 58-65
    • Raehal, K.M.1    Bohn, L.M.2
  • 41
    • 77951844975 scopus 로고    scopus 로고
    • Teaching old receptors new tricks: Biasing seven-transmembrane receptors
    • Rajagopal S, Rajagopal K, Lefkowitz RJ (2010) Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nat Rev Drug Discov 9:373–386.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 373-386
    • Rajagopal, S.1    Rajagopal, K.2    Lefkowitz, R.J.3
  • 42
    • 84855901533 scopus 로고    scopus 로고
    • Molecular mechanism of beta-arrestin-biased agonism at seven-transmembrane receptors
    • Reiter E, Ahn S, Shukla AK, Lefkowitz RJ (2012) Molecular mechanism of beta-arrestin-biased agonism at seven-transmembrane receptors. Annu Rev Pharmacol Toxicol 52:179–197.
    • (2012) Annu Rev Pharmacol Toxicol , vol.52 , pp. 179-197
    • Reiter, E.1    Ahn, S.2    Shukla, A.K.3    Lefkowitz, R.J.4
  • 45
    • 84958527704 scopus 로고    scopus 로고
    • Arrestin interaction with E3 ubiquitin ligases and deubiquitinases: Functional and therapeutic implications
    • Shenoy SK (2014) Arrestin interaction with E3 ubiquitin ligases and deubiquitinases: functional and therapeutic implications. Handb Exp Pharmacol 219:187–203.
    • (2014) Handb Exp Pharmacol , vol.219 , pp. 187-203
    • Shenoy, S.K.1
  • 46
    • 80052038573 scopus 로고    scopus 로고
    • Beta-Arrestin-mediated receptor trafficking and signal transduction
    • Shenoy SK, Lefkowitz RJ (2011) beta-Arrestin-mediated receptor trafficking and signal transduction. Trends Pharmacol Sci 32:521–533.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 521-533
    • Shenoy, S.K.1    Lefkowitz, R.J.2
  • 48
    • 84890783779 scopus 로고    scopus 로고
    • Endocytic profiles of delta-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses
    • Tudashki HB, Robertson DN, Schiller PW, Pineyro G (2014) Endocytic profiles of delta-opioid receptor ligands determine the duration of rapid but not sustained cAMP responses. Mol Pharmacol 85:148–161.
    • (2014) Mol Pharmacol , vol.85 , pp. 148-161
    • Tudashki, H.B.1    Robertson, D.N.2    Schiller, P.W.3    Pineyro, G.4
  • 49
    • 84876918645 scopus 로고    scopus 로고
    • Pharmacological traits of delta opioid receptors: Pitfalls or opportunities?
    • van Rijn RM, Defriel JN, Whistler JL (2013) Pharmacological traits of delta opioid receptors: pitfalls or opportunities? Psychopharmacology 228: 1–18.
    • (2013) Psychopharmacology , vol.228 , pp. 1-18
    • Van Rijn, R.M.1    Defriel, J.N.2    Whistler, J.L.3
  • 50
    • 27844524967 scopus 로고    scopus 로고
    • Induction of delta opioid receptor function by up-regulation of membrane receptors in mouse primary afferent neurons
    • Walwyn W, Maidment NT, Sanders M, Evans CJ, Kieffer BL, Hales TG (2005) Induction of delta opioid receptor function by up-regulation of membrane receptors in mouse primary afferent neurons. Mol Pharmacol 68:1688–1698.
    • (2005) Mol Pharmacol , vol.68 , pp. 1688-1698
    • Walwyn, W.1    Maidment, N.T.2    Sanders, M.3    Evans, C.J.4    Kieffer, B.L.5    Hales, T.G.6
  • 52
    • 23944458138 scopus 로고    scopus 로고
    • A general framework for weighted gene coexpression network analysis
    • Zhang B, Horvath S (2005) A general framework for weighted gene coexpression network analysis. Stat Appl Genet Mol Biol 4:Article17.
    • (2005) Stat Appl Genet Mol Biol , vol.4
    • Zhang, B.1    Horvath, S.2
  • 53
    • 25644455241 scopus 로고    scopus 로고
    • Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors
    • Zhang X, Wang F, Chen X, Li J, Xiang B, Zhang YQ, Li BM, Ma L (2005) Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors. J Neurochem 95:169–178.
    • (2005) J Neurochem , vol.95 , pp. 169-178
    • Zhang, X.1    Wang, F.2    Chen, X.3    Li, J.4    Xiang, B.5    Zhang, Y.Q.6    Li, B.M.7    Ma, L.8
  • 54
    • 51649112003 scopus 로고    scopus 로고
    • Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms
    • Zhang X, Wang F, Chen X, Chen Y, Ma L (2008) Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms. J Neurochem 106: 781–792.
    • (2008) J Neurochem , vol.106 , pp. 781-792
    • Zhang, X.1    Wang, F.2    Chen, X.3    Chen, Y.4    Ma, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.