Role of Src in ligand-specific regulation of δ-opioid receptor desensitization and internalization

Journal of Neurochemistry

Volumn 108, Issue 1, 2009, Pages 102-114

  Hong, Min Hua ^a   Xu, Chi ^a   Wang, Yu Jun ^a   Ji, Jing Li ^a   Tao, Yi Min ^a   Xu, Xue Jun ^a   Chen, Jie ^a   Xie, Xin ^a   Chi, Zhi Qiang ^a   Liu, Jing Gen ^a,b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b Zhangjiang Hi Tech Park   (China)

Author keywords

arrestin; opioid receptor; Desensitization; GRK2; Internalization; Src

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENYLATE CYCLASE; BETA ARRESTIN 1; DELTA OPIATE RECEPTOR; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; G PROTEIN COUPLED RECEPTOR KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MORPHINE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DESENSITIZATION; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE TRANSLOCATION; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANALGESICS, OPIOID; ANIMALS; ARRESTINS; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, D-PENICILLAMINE (2,5)-; FLOW CYTOMETRY; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MITOGEN-ACTIVATED PROTEIN KINASE 3; MORPHINE; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, OPIOID, DELTA; SERINE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TETRAHYDROISOQUINOLINES; TRANSFECTION;

EID: 57249108263     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05740.x     Document Type: Article

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