Deciphering μ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells

British Journal of Pharmacology

Volumn 167, Issue 6, 2012, Pages 1259-1270

  Doll, Christian ^a   Pöll, Florian ^a   Peuker, Kenneth ^a   Loktev, Anastasia ^a   Glück, Laura ^a   Schulz, Stefan ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

GRK; internalization; morphine; opioid receptor; phosphatase; phosphorylation

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; G PROTEIN COUPLED RECEPTOR KINASE 5; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 1GAMMA; SERINE; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CATALYSIS; CELL MEMBRANE; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANALGESICS, OPIOID; ANTIBODIES; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; G-PROTEIN-COUPLED RECEPTOR KINASES; HEK293 CELLS; HUMANS; MORPHINE; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; RECEPTORS, OPIOID, MU; RNA, SMALL INTERFERING;

EID: 84867802836     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02080.x     Document Type: Article

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