Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease

Nature

Volumn 531, Issue 7595, 2016, Pages 508-512

  Roy, Dheeraj S ^a   Arons, Autumn ^a   Mitchell, Teryn I ^a   Pignatelli, Michele ^a   Ryan, Tomás J ^a   Tonegawa, Susumu ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS AND CELL COMPONENTS; CONSOLIDATION; LONG-TERM CHANGE; MEMORY; NERVOUS SYSTEM DISORDER; NUMERICAL MODEL; RODENT; THEORETICAL STUDY;

ALZHEIMER DISEASE; AMNESIA; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL DENSITY; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC SPINE; DENTATE GYRUS; ENGRAM CELL; EPISODIC MEMORY; GRANULE CELL; HIPPOCAMPUS; INFORMATION RETRIEVAL; LOCOMOTION; LONG TERM MEMORY; MEMORY; NERVE CELL; NONHUMAN; OPTOGENETICS; PERFORANT NERVE TRACT; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; AGING; ANIMAL; CYTOLOGY; DISEASE MODEL; EARLY INTERVENTION; GENETICS; HUMAN; LONG TERM POTENTIATION; MALE; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPSE; TRANSGENE; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

AMYLOID PRECURSOR PROTEIN; MAPT PROTEIN, HUMAN; PRESENILIN 1; TAU PROTEIN;

AGING; ALZHEIMER DISEASE; AMNESIA; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DENDRITIC SPINES; DENTATE GYRUS; DISEASE MODELS, ANIMAL; EARLY MEDICAL INTERVENTION; HUMANS; LONG-TERM POTENTIATION; MALE; MEMORY, EPISODIC; MEMORY, LONG-TERM; MICE; MICE, TRANSGENIC; OPTOGENETICS; PLAQUE, AMYLOID; PRESENILIN-1; SYNAPSES; TAU PROTEINS; TRANSGENES;

EID: 84961616024     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17172     Document Type: Article

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