Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

Oncogene

Volumn 35, Issue 40, 2016, Pages 5263-5271

  Vellinga, T T ^a   Den Uil, S ^b,c   Rinkes, I H B ^a   Marvin, D ^a   Ponsioen, B ^a   Alvarez Varela, A ^a   Fatrai, S ^a   Scheele, C ^a   Zwijnenburg, D A ^d   Snippert, H ^a   Vermeulen, L ^d   Medema, J P ^d   Stockmann, H B ^c   Koster, J ^d   Fijneman, R J A ^b,e   De Rooij, J ^c   Kranenburg, O ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Infection and Immunology   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; HEPATOCYTE NUCLEAR FACTOR 4; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST1; TRANSCRIPTION FACTOR TWIST2; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; HNF4A PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CELL DIFFERENTIATION; COLON CANCER; EPITHELIAL CANCER CELL LINE; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; HUMAN; MESENCHYME CELL; NONHUMAN; PRIORITY JOURNAL; STROMA; TUMOR INVASION; TUMOR MICROENVIRONMENT; CELL MOTION; CELL PROLIFERATION; COLON TUMOR; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; STROMA CELL; TUMOR CELL LINE;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLLAGEN; COLONIC NEOPLASMS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; STROMAL CELLS; TUMOR MICROENVIRONMENT;

EID: 84961390342     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2016.60     Document Type: Article

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