Presence of twist1-positive neoplastic cells in the stroma of chromosome-unstable colorectal tumors

Gastroenterology

Volumn 145, Issue 3, 2013, Pages

  Celesti, Giuseppe ^a   Di Caro, Giuseppe ^a   Bianchi, Paolo ^a   Grizzi, Fabio ^a   Basso, Gianluca ^a   Marchesi, Federica ^a   Doni, Andrea ^a   Marra, Giancarlo ^b   Roncalli, Massimo ^b,c   Mantovani, Alberto ^a,c   Malesci, Alberto ^b,c   Laghi, Luigi ^a,b  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Colon Cancer; Metastasis; MSI; Tumor Invasion

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST 1; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; CANCER CELL CULTURE; CHROMOSOME; CHROMOSOME 20; CHROMOSOME 7; CLINICAL ARTICLE; COLON CARCINOMA; COLORECTAL TUMOR; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FLUORESCENCE IN SITU HYBRIDIZATION; GENE OVEREXPRESSION; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MESENCHYMAL STROMA CELL; MICROSATELLITE INSTABILITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA; TIME; TRISOMY; TUMOR CELL;

EID: 84883192492     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.05.011     Document Type: Article

References (44)

1. D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
2. E.D. Hay The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it Dev Dyn 233 2005 706 720
3. M. Zeisberg, and E.G. Neilson Biomarkers for epithelial-mesenchymal transitions J Clin Invest 119 2009 1429 1437
4. J. Yang, S.A. Mani, and J.L. Donaher Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis Cell 117 2004 927 939
5. I. Gitelman Twist protein in mouse embryogenesis Dev Biol 189 1997 205 214
6. M.A. Eckert, T.M. Lwin, and A.T. Chang Twist1-induced invadopodia formation promotes tumor metastasis Cancer Cell 19 2011 372 386
7. Y. Kang, and J. Massague Epithelial-mesenchymal transitions: twist in development and metastasis Cell 118 2004 277 279
8. G. Moreno-Bueno, H. Peinado, and P. Molina The morphological and molecular features of the epithelial-to-mesenchymal transition Nat Protoc 4 2009 1591 1613
9. H. Peinado, D. Olmeda, and A. Cano Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7 2007 415 428
10. J.P. Thiery, H. Acloque, and R.Y. Huang Epithelial-mesenchymal transitions in development and disease Cell 139 2009 871 890
11. D.S. Micalizzi, S.M. Farabaugh, and H.L. Ford Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression J Mammary Gland Biol Neoplasia 15 2010 117 134
12. O. Schmalhofer, S. Brabletz, and T. Brabletz E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer Cancer Metastasis Rev 28 2009 151 166
13. M.H. Yang, M.Z. Wu, and S.H. Chiou Direct regulation of TWIST by HIF-1alpha promotes metastasis Nat Cell Biol 10 2008 295 305
14. D. Tarin, E.W. Thompson, and D.F. Newgreen The fallacy of epithelial mesenchymal transition in neoplasia Cancer Res 65 2005 5996 6000 discussion 6000-6001
15. J. Zavadil, and E.P. Bottinger TGF-beta and epithelial-to-mesenchymal transitions Oncogene 24 2005 5764 5774
16. K. Hur, Y. Toiyama, and M. Takahashi MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis Gut 2012 Epub ahead of print
17. C. Franci, M. Gallen, and F. Alameda Snail1 protein in the stroma as a new putative prognosis marker for colon tumours PLoS One 4 2009 e5595
18. I. Gomez, C. Pena, and M. Herrera TWIST1 is expressed in colorectal carcinomas and predicts patient survival PLoS One 6 2011 e18023
19. Y. Soini, H. Tuhkanen, and R. Sironen Transcription factors zeb1, twist and snai1 in breast carcinoma BMC Cancer 11 2011 73
20. F. Valdes-Mora, T. Gomez del Pulgar, and E. Bandres TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer Ann Surg Oncol 16 2009 78 87
21. M. Hu, J. Yao, and D.K. Carroll Regulation of in situ to invasive breast carcinoma transition Cancer Cell 13 2008 394 406
22. M. Donigan, B.D. Loh, and L.S. Norcross A metastatic colon cancer model using nonoperative transanal rectal injection Surg Endosc 24 2010 642 647
23. J. Bastid EMT in carcinoma progression and dissemination: facts, unanswered questions, and clinical considerations Cancer Metastasis Rev 31 2012 277 283
24. T. Hasebe, M. Iwasaki, and S. Akashi-Tanaka p53 expression in tumor-stromal fibroblasts forming and not forming fibrotic foci in invasive ductal carcinoma of the breast Mod Pathol 23 2010 662 672
25. A. Patocs, L. Zhang, and Y. Xu Breast-cancer stromal cells with TP53 mutations and nodal metastases N Engl J Med 357 2007 2543 2551
26. K. Ishiguro, T. Yoshida, and H. Yagishita Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas Gut 55 2006 695 702
27. E.T. Liu Stromal effects in breast cancer N Engl J Med 357 2007 2537 2538
28. I. Campbell, K. Polyak, and I. Haviv Clonal mutations in the cancer-associated fibroblasts: the case against genetic coevolution Cancer Res 69 2009 6765 6768 discussion 6769
29. K. Polyak Heterogeneity in breast cancer J Clin Invest 121 2011 3786 3788
30. M. Hoglund, D. Gisselsson, and G.B. Hansen Dissecting karyotypic patterns in colorectal tumors: two distinct but overlapping pathways in the adenoma-carcinoma transition Cancer Res 62 2002 5939 5946
31. A. Nanashima, H. Yamaguchi, and T. Yasutake Gain of chromosome 20 is a frequent aberration in liver metastasis of colorectal cancers Dig Dis Sci 42 1997 1388 1393
32. A. Malesci, L. Laghi, and P. Bianchi Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancer Clin Cancer Res 13 2007 3831 3839
33. M.S. Pino, H. Kikuchi, and M. Zeng Epithelial to mesenchymal transition is impaired in colon cancer cells with microsatellite instability Gastroenterology 138 2010 1406 1417
34. C.B. Diep, K. Kleivi, and F.R. Ribeiro The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes Genes Chromosomes Cancer 45 2006 31 41
35. G. Bardi, B. Johansson, and N. Pandis Trisomy 7 in short-term cultures of colorectal adenocarcinomas Genes Chromosomes Cancer 3 1991 149 152
36. G. Barriere, A. Riouallon, and J. Renaudie Mesenchymal and stemness circulating tumor cells in early breast cancer diagnosis BMC Cancer 12 2012 114
37. O.H. Ocana, R. Corcoles, and A. Fabra Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1 Cancer Cell 22 2012 709 724
38. J.H. Tsai, J.L. Donaher, and D.A. Murphy Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis Cancer Cell 22 2012 725 736
39. H. Ledford Cancer theory faces doubts Nature 472 2011 273
40. B.J. van Denderen, and E.W. Thompson Cancer: the to and fro of tumour spread Nature 493 2013 487 488
41. S.A. Joosse, and K. Pantel Biologic challenges in the detection of circulating tumor cells Cancer Res 73 2013 8 11
42. R. Marais, W. Sellers, and D. Livingston Twenty-fourth Annual Pezcoller Symposium: molecular basis for resistance to targeted agents Cancer Res 73 2013 1046 1049
43. L. Guo, E.K. Lobenhofer, and C. Wang Rat toxicogenomic study reveals analytical consistency across microarray platforms Nat Biotechnol 24 2006 1162 1169
44. W. Huang da, B.T. Sherman, and R.A. Lempicki Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat Protoc 4 2009 44 57