Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients

Cellular Oncology

Volumn 31, Issue 3, 2009, Pages 169-178

  Mesker, Wilma E ^a   Liefers, Gerrit Jan ^b   Junggeburt, Jan M C ^b   Van Pelt, Gabi W ^b   Alberici, Paola ^a   Kuppen, Peter J K ^b   Miranda, Noel F ^b   Van Leeuwen, Karin A M ^c   Morreau, Hans ^b   Szuhai, Karoly ^a   Tollenaar, Rob A E M ^b   Tanke, Hans J ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RIJNLAND HOSPITAL   (Netherlands)

Author keywords

Colon cancer; High risk patients; Primary tumor; Prognosis; Stroma

Indexed keywords

BETA CATENIN; BIOLOGICAL MARKER; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

AGED; ARTICLE; CANCER CELL; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CELL TRANSFORMATION; COLON CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; DOWN REGULATION; FEMALE; HIGH RISK POPULATION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRA TUMOR STROMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STROMA;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COLONIC NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; SMAD4 PROTEIN; STROMAL CELLS; SURVIVAL ANALYSIS;

EID: 67650248525     PISSN: 15705870     EISSN: None     Source Type: Journal    
DOI: 10.3233/CLO-2009-0478     Document Type: Article

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